Clinical trials: EUS
Pancreatic Cancer
PurIST Classification-Guided Adaptive Neoadjuvant Chemotherapy by RNA Expression Profiling of EUS Aspiration Samples
This is an open-label, phase II study in patients with resectable and borderline resectable pancreatic cancer.
- Trial name
- PANCREAS (NCT04683315)
- Testing
- mFOLFIRINOX Treatment Regimen, Gemcitabine/Nab-paclitaxel Treatment Regimen
- Where
- 2 sites in United States
- Volunteers
- 84 people
- Sponsor
- Medical College of Wisconsin
Cancer of Pancreas, Pancreatic Neoplasms
EUS-Coeliac Plexus Block Versus Radiofrequency Ablation in Pain Relief of Patients With Malignancy
Many cancer patients suffer from intractable pain and which is often suboptimally controlled by even strong opioid analgesics. Coeliac plexus neurolysis (CPN) is procedure which intended to permanently destroy the nociceptive…
- Conditions
- Cancer of Pancreas, Pancreatic Neoplasms, Pain, Cancer-Associated Pain
- Trial name
- NCT04809935
- Testing
- 98% dehydrated alcohol, 19G EUSRA needle, Taewoong Medical, Korea
- Where
- Hong Kong
- Volunteers
- 54 people
- Sponsor
- The University of Hong Kong
Pancreatic Cancer
EUS-CPN With and Without Bupivacaine
Endoscopic ultrasound (EUS) allows EUS-guided trans gastric injection of absolute alcohol around the base of the celiac plexus (celiac plexus neurolysis (EUS-CPN)), to help alleviate pain associated with pancreatic cancer.
- Trial name
- EUS-NB (NCT04951804)
- Testing
- EUS-CPN without bupivacaine, EUS-CPN with bupivacaine
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Pancreatic Cancer
EUS-CPN: A Retrospective Review
The purpose of this retrospective study is to measure the safety of EUS-CPN in patients that have undergone this procedure in the last decade.
- Trial name
- NCT00577564
- Where
- United States
- Sponsor
- Indiana University
Pancreas Mass Diagnosis
Comparing Methods to Biopsy Pancreas Mass
This study will examine whether there is any difference in number of passes needed to diagnose pancreatic masses during endoscopic ultrasound-guided biopsies using 2 different types of needles.
- Trial name
- NCT01663493
- Testing
- FNB
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Brigham and Women's Hospital
Efficacy, Safety
EUS-guided Ethanol-lipiodol Ablation of Pancreatic Neuroendocrine Tumor: a Prospective Study
The present study evaluate the safety and efficacy of EUS-guided ethanol-lipiodol ablation for the treatment of pancreatic NET
- Conditions
- Efficacy, Safety, Feasibility
- Trial name
- EUS (NCT01902238)
- Testing
- EUS-guided ethanol-lipiodol mixture ablation
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Asan Medical Center
Liver Diseases
Safety and Efficacy of Endoscopic Ultrasound-Guided Portal Pressure Gradient Measurement
The purpose of this study is to evaluate the efficacy, safety, and adequacy of Endoscopic Ultrasound (EUS) Portal Pressure Gradient Measurement (PPGM) in patients undergoing EUS-guided liver biopsies.
- Trial name
- NCT06336850
- Testing
- Endoscopic Ultrasound-Guided Portal Pressure Gradient Measurement
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Methodist Health System
Early Rectal Cancer
The Diagnosis of Invasive Depth of Early Rectal Cancer
The purpose of this clinical study is to compare the accuracy of linear endoscopic ultrasonography and magnified narrowband endoscopy in the diagnosis of invasive depth of early rectal cancer, and to provide more powerful…
- Trial name
- NCT04222530
- Testing
- Linear EUS first, ME-NBI first
- Volunteers
- 81 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Obesity, Non-Alcoholic Steatohepatitis
EUS Guided Core Liver Biopsy and IGB Placement for the Diagnosis and Management of NASH and Obesity
This study is designed to investigate the impact of weight loss achieved with the IGB on NASH with early fibrosis in a select cohort of patients with obesity preselected to have a high pre-test probability of having NASH with…
- Trial name
- NCT02880189
- Testing
- Orbera Intragastric Balloon, Endoscopic Ultrasound Guided Core Liver Biopsy
- Volunteers
- 21 people
- Sponsor
- Mayo Clinic
Sarcoidosis, Pulmonary
Endobronchial Ultrasound Strain Elastography in Sarcoidosis
Strain elastography (SE) is an imaging method used for the measurement of relative tissue elasticity through qualitative (color pattern) or semi-quantitative methods (strain ratio or strain histogram).
- Trial name
- NCT04895111
- Testing
- Endobronchial ultrasound strain elastography
- Where
- Italy
- Volunteers
- 701 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Malignant Biliary Obstruction
EUS-guided Hepatico-gastrostomy With Hot Giobor
Endoscopic ultrasonography-guided hepaticogastrostomy (EUS-HGS) is a method of obtaining biliary drainage in patients with failed or difficult endoscopic retrograde cholangiopancreatography (ERCP).
- Trial name
- NCT05804201
- Testing
- EUS-guided hepatico-gastrostomy would be performed with Niti-S HOT Giob
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- Chinese University of Hong Kong
Liver Cirrhosis
Comparing a Direct Versus an Indirect Approach to Measuring the Portalsytemic Pressure Gradients
The objective of this study is to evaluate the correlation of the calculated portosystemic pressure gradient (PPG) obtained by direct portal and hepatic pressure measurements with the EchoTip® Insight™ and indirect portal vein…
- Trial name
- NCT04987034
- Testing
- EchoTip® Insight™
- Where
- 3 sites in Belgium, Netherlands and 1 more
- Volunteers
- 35 people
- Sponsor
- Cook Research Incorporated
Esophageal Cancer
Endobronchial Ultrasound (EBUS) for Nodal Staging in Esophageal Cancer
The purpose of this study is determine if performing endobronchial ultrasound (EBUS) in addition to standard endoscopic ultrasound (EUS) can increase the precision and accuracy of staging esophageal cancer in comparison to EUS…
- Trial name
- CT0003 (NCT01038544)
- Testing
- Endoscopic Ultrasound (EUS), Endobronchial Ultrasound (EBUS)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Endoscopic Ultrasound
High Flow Nasal Cannula Compared to Standard Oxygen for Endoscopic Ultrasound
The purpose of the study is to evaluate the use of high flow nasal cannula versus standard oxygen therapy for high-risk patients undergoing endoscopy procedures.
- Trial name
- NCT06704867
- Testing
- High flow nasal cannula
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mayo Clinic
Pancreatic Cancer
Comparison Between Base and Cover Slide From Endoscopic Ultrasound Guided Fine Needle Aspiration for Pancreatic Cancer
The purpose of this study is to determine whether there is a difference of diagnostic accuracy between cover slides and base slides from EUS-FNA cytopathologic sample in patients who were previously suspected of pancreatic cancer…
- Trial name
- EUS-FNA (NCT02190071)
- Where
- South Korea
- Volunteers
- 73 people
- Sponsor
- Seoul National University Hospital
Acute Cholecystitis
Endoscopic Ultrasonography (EUS) Guided Gallbladder Drainage With Two Months Stent Removal for Acute Cholecystitis: a Prospective Study
Acute cholecystitis (AC) is defined as an acute inflammatory disease of the gallbladder consequently to the presence of sludge or stones. AC accounts for 3-10% of all cases of abdominal pain.
- Trial name
- AC LAMS (NCT05272007)
- Testing
- EUS-biliary drainage
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto Clinico Humanitas Mater Domini
Therapeutic Endoscopic Ultrasound, Advanced Endoscopy
Therapeutic Endoscopic Ultrasound for Gastrointestinal Disorders: A Multicenter Registry Study
The purpose of this retrospective chart-review registry study is to evaluate the safety profile, efficacy profile and cost-effectiveness of the various therapeutic endoscopic ultrasound (EUS) procedures (for benign and malignant…
- Conditions
- Therapeutic Endoscopic Ultrasound, Advanced Endoscopy, Therapeutic Endoscopy, Interventional Endoscopy
- Trial name
- TEUS Registry (NCT05051358)
- Testing
- Therapeutic Endoscopic Ultrasound
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Advanced Endoscopy Research, Robert Wood Johnson Medical School Rutgers University
Fundal Gastric Varices, Endoscopic Ultrasound (EUS)-Guided Coil Deployment
Clip and Coil in Fundal Gastric Varices With a Large Shunt
Endoscopic ultrasound (EUS)-guided coil deployment is a promising technique for the endoscopic management of gastric varices. However, coil migration may occur in patients with large drainage collaterals.
- Conditions
- Fundal Gastric Varices, Endoscopic Ultrasound (EUS)-Guided Coil Deployment, Titanium Clips, Ectopic Embolization
- Trial name
- NCT07263503
- Where
- China
- Volunteers
- 31 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Obstructive Jaundice, Pancreatic Cancer
Endoscopic Ultrasound-guided Biliary Drainage for Malignant Biliary Obstruction After Failed ERCP
In this study the investigators retrospectively report outcomes of direct transluminal EUS-BD in a series of patients with malignant biliary obstruction after failed ERCP as the experience of a single Italian center
- Trial name
- (EUS-BD) (NCT03510754)
- Testing
- Eus guided biliary drainage
- Volunteers
- 36 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Pancreatic Pseudocyst, Pancreatic Necrosis
EUS-guided Transenteric Drainage With a Novel Lumen-apposing Metal Stent
To evaluate clinical efficacy and safety of a novel lumen-apposing FCSEMS for EUS-guided transenteric drainage of PFC or of biliary tree including GB
- Conditions
- Pancreatic Pseudocyst, Pancreatic Necrosis, Biliary Obstruction, Acute Cholecystitis
- Trial name
- NCT03002051
- Testing
- EUS-guided drainage
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Chinese University of Hong Kong