Clinical trials: EUS
IPMN, Pancreatic
A Long-term Follow-up Cohort Study in Patients With Intraductal Papillary Mucinous Neoplasm
Study objective: To establish a long-term follow-up cohort of patients with IPMN, study the follow-up, clinical outcomes and prognostic factors of patients with IPMN, and provide a basis for clinical decisions and guidelines.
- Trial name
- NCT05593393
- Testing
- Endoscopic ultrasound
- Volunteers
- 1,500 people
- Sponsor
- Peking Union Medical College Hospital
Pancreatic Adenocarcinoma, Lymph Node Metastasis
EUS Role in Non-metastatic Pancreatic Adenocarcinoma Lymph Nodes Staging
Aim of the study will be to investigate if Endoscopic Ultrasound (EUS) with elastography can be purposed between the routine staging examinations in patients with pancreatic adenocarcinoma without distant metastasis for the…
- Trial name
- NCT06341725
- Testing
- malignant lymph nodes
- Where
- Italy
- Volunteers
- 2 people
- Sponsor
- Paolo Giorgio Arcidiacono, MD
Pancreatic Cyst
EUS-guided Through-the-needle Microforceps Biopsy Outcomes
INTRODUCTION: The diagnosis of pancreatic cystic lesions (PCLs) is increasing due to improvements of cross-sectional imaging. It is mandatory, for appropriate management, to make an accurate diagnosis and risk stratification…
- Trial name
- NCT04140435
- Testing
- EUS-guided through-the-needle microbiopsy forceps (Moray)
- Where
- Argentina
- Volunteers
- 50 people
- Sponsor
- Institute of Gastroenterology and Advance Endoscopy
Gastric Cancer
"Mechanisms and Biomarkers of Response and Resistance to Current Targeted Therapies in Gastric Cancer" (THERRES)
The main aim was to assess the tumor vascular perfusion pattern in gastric cancer (GC). The investigators used dynamic contrast harmonic imaging endoscopic ultrasound (CHI-EUS) and the results were compared with the…
- Trial name
- THERRES (NCT05051423)
- Testing
- Endoscopic ultrasound
- Where
- Romania
- Volunteers
- 40 people
- Sponsor
- University of Medicine and Pharmacy Craiova
E01.370.350.850.280, I02.399
Global Assessment of Endoscopic Ultrasound Performance Skills
Endoscopic ultrasound (EUS) is a mini-invasive diagnostic procedure in the work-up of various suspicious malignancies. The learning curve of EUS is regarded long but so far the literature of this topic is minimal.
- Conditions
- E01.370.350.850.280, I02.399, J01.897.608, N06.850.135.060.075.399
- Trial name
- NCT02455570
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Sahlgrenska University Hospital
Pancreatic Neuroendocrine Tumor
ATRX/DAXX in EUS-FNB Specimens of Pan-NETs
P-NENs are classified as functional (F-) or non-functional (NF-) depending on the presence or absence of a clinical hormonal hypersecretion syndrome.
- Trial name
- FORESEE (NCT06406387)
- Testing
- ATRX/DAXX immunohistochemistry
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Pancreatitis Acute Biliary
Early Endoscopic Ultrasound - Based Sphincterotomy or Conservative Treatment in Severe Biliary Pancreatitis
The primary purpose of this trial is to determine whether an early Early Endoscopic Ultrasound (EUS) immediately followed by an endoscopic sphincterotomy (ES) in case of bile duct stones may improve outcomes in patients with…
- Trial name
- EEPAB2 (NCT00987428)
- Testing
- ultrasonography with or not sphincterotomy, Usual procedure
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Liver Graft Dysfunction
Utility of Combined EUS and ERCP Procedures in the Evaluation of Liver Graft Dysfunction
The purpose of this investigator-initiated study is to determine whether a single-step session that combines endoscopic ultrasound (which may further include liver biopsy and needle-guided cholangiography) with endoscopic…
- Trial name
- NCT04841278
- Testing
- EUS/ERCP
- Sponsor
- Loma Linda University
Autoimmune Pancreatitis, Pancreatic Cancer
To Differentiate Focal Autoimmune Pancreatitis From Pancreatic Cancer by Endoscopic Ultrasound
Autoimmune pancreatitis (AIP) is a special type of chronic pancreatitis mediated by autoimmunity. The classic manifestation of AIP is diffuse pancreatic enlargement, some of which are characterized by focal enlargement.
- Trial name
- NCT04834505
- Testing
- Diagnostic imaging modalities for validation sample, EUS for derivation sample
- Where
- China
- Volunteers
- 286 people
- Sponsor
- Peking Union Medical College Hospital
EUS-FNA, Rectal Cancer
TRUS-FNA For The Prediction Of pCR After Neoadjuvant Treatment In Rectal Cancer
Colorectal cancer is one of the most malignancies worldwide. The dominant clinical research strategy of LARC includes neoadjuvant chemoradiotherapy before radical surgery followed combined with adjuvant treatment.
- Conditions
- EUS-FNA, Rectal Cancer, Pathological Complete Remission
- Trial name
- NCT04939103
- Testing
- TRUS-FNA
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Pancreatic Neoplasms
EUS-FNB With MOSE vs EUS-FNA With ROSE
Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is an indispensable tool for tissue acquisition for pancreatic lesions.
- Trial name
- MORE (NCT03766659)
- Testing
- MOSE, ROSE
- Where
- Hong Kong
- Volunteers
- 340 people
- Sponsor
- Chinese University of Hong Kong
Chronic Liver Disease (CLD), Liver Transplantation
Patient Reported Outcomes In Liver Biopsy (EUS vs. Percutaneous)
Patient Experience in Endohepatology Liver biopsy is a crucial procedure for the diagnosis and/or staging of liver diseases. Common indications for non-targeted biopsies include unexplained elevated liver function tests (LFTs)…
- Conditions
- Chronic Liver Disease (CLD), Liver Transplantation, Cirrhosis
- Trial name
- PRO-LIVER (NCT07506642)
- Testing
- EUS Liver Biopsy, Percutaneous Liver Biopsy
- Where
- Germany
- Volunteers
- 102 people
- Sponsor
- University Hospital Muenster
Malignant Biliary Obstruction
EUS - Guided Choledocho-duodenostomy Versus ERCP With Covered Metallic Stents in Patients With Unresectable Malignant Distal Common Bile Duct Strictures
EUS - guided choledocho-duodenostomy (ECDS) is an established option for bile duct drainage in unresectable malignant distal CBD strictures when endoscopic retrograde cholangiopancreatography (ERCP) fails.
- Trial name
- DRAMBO (NCT03000855)
- Testing
- EUS-guided choledocho-duodenostomy, Endoscopic retrograde cholangiopancreatography with covered metallic stent
- Where
- 6 sites in Australia, Belgium and 3 more
- Volunteers
- 77 people
- Sponsor
- Chinese University of Hong Kong
Adenocarcinoma Pancreas, Chronic Pancreatitis
Contrast Enhanced Harmonic Endoscopic Ultrasound (CEH-EUS) in Focal Pancreatic Masses
The aim of the study is to assess the accuracy of real-time perfusion imaging pattern of pancreatic focal lesions visualized by contrast-enhanced harmonic endoscopic ultrasound (CEH-EUS) for the differential diagnosis between…
- Trial name
- NCT01315548
- Where
- 14 sites in Denmark, France and 6 more
- Volunteers
- 210 people
- Sponsor
- University of Medicine and Pharmacy Craiova
Acute Cholecystitis
EUS-guided Gallbladder Drainage Instead of Laparoscopic Cholecystectomy for Acute Cholecystitis. A Feasibility Study.
To evaluate the feasibility of performing EGBD as a treatment of acute calculous cholecystitis in patients that are indicated for laparoscopic cholecystectomy.
- Trial name
- EGDB (NCT04197908)
- Testing
- EUS-guided gallbladder drainage (EGBD)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Chinese University of Hong Kong
Non-Alcoholic Fatty Liver Disease, Non-alcoholic Steatohepatitis
Endoscopic Ultrasound Shear Wave Elastography in Patients With Non-alcoholic Fatty Liver Disease
The goal of this observation study is to assess whether endoscopic ultrasound shear wave elastography (EUS-SWE) may be a useful tool for liver fibrosis screening in patients with elevated body mass index and non alcoholic fatty…
- Conditions
- Non-Alcoholic Fatty Liver Disease, Non-alcoholic Steatohepatitis, Obesity
- Trial name
- NCT05728697
- Testing
- Endoscopic ultrasound shear wave elastography
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Brigham and Women's Hospital
Competency Based Education
Rapid Assessment of Trainee Endoscopy Skills (RATES) Study Two
The establishment of a number of training programs in therapeutic endoscopy, standardization of the performance of endoscopic ultrasound (EUS) and endoscopy retrograde cholangiopancreatography (ERCP) and definition of competence…
- Trial name
- RATES 2 (NCT02509416)
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Hilar Cholangiocarcinoma, Intrahepatic Cholangiocarcinoma
Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma
The goal of this observational cohort study is to assess the yield of preoperative endoscopic ultrasound focussed on lymph nodes in patients with presumed resectable perihilar (pCCA), intrahepatic (iCCA) or mid-common bile duct…
- Conditions
- Hilar Cholangiocarcinoma, Intrahepatic Cholangiocarcinoma, Common Bile Duct Neoplasms, Cholangiocarcinoma
- Trial name
- POELH-II (NCT05678218)
- Testing
- Endoscopic Ultrasound registration
- Where
- 7 sites in Belgium, Netherlands
- Volunteers
- 245 people
- Sponsor
- Erasmus Medical Center
Pancreatitis, Chronic
Prospective Study on Endoscopic Ultrasound (EUS) Celiac Bloc Efficacy in Chronic Pancreatitis
The purpose of this study is to determine if celiac bloc (with injection of steroid and local anesthetic) is superior to a sham procedure for pain control and quality of life improvement in patient with chronic pancreatitis and…
- Trial name
- NCT01318590
- Testing
- EUS procedure with drug injection, EUS procedure
- Where
- 2 sites in Belgium, Canada
- Volunteers
- 2 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Pancreatic Masses
The Use of a New Core Needle in the Endoscopic Ultrasound Assisted Tissue Sampling for Pancreatic Solid Masses
Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNA) is a reliable, safe, and effective technique for obtaining samples from pancreatic masses.
- Trial name
- NCT02946840
- Testing
- FNA with 25 G Beacon needle
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Istituto Clinico Humanitas