Clinical trials: EUS-FNA
Solid Pancreatic Mass Lesions, Malignant Neoplasm of Pancreas
Comparison of a Novel 22-gauge Core Biopsy Needle
The goal of this clinical research study is to compare the performance of a newly available needle with reverse bevel design (called the EchoTip® Procore™ needle) with standard needles to see which needle gives better diagnostic…
- Trial name
- NCT01598194
- Testing
- Novel 22-gauge Core Biopsy Needle + Standard Biopsy Needle
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- M.D. Anderson Cancer Center
Pancreatic Diseases
The 22G Trident Needle Combined With Different Aspiration Techniques for Endoscopic Ultrasound-guided Fine-needle Biopsy
The goal of this clinical study is to compare the tissue adequacy, cellularity, blood contamination, accuracy, sensitivity, specificity of the 22G Trident needle combined with three different aspiration techniques (dry-suction…
- Trial name
- NCT07023562
- Testing
- ABC suction sequence, ACB suction sequence, BAC suction sequence
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Changhai Hospital
Pancreaticobiliary Cancers, Jaundice
Endoscopic Ultrasound Versus Endoscopic Retrograde Cholangiopancreatography (ERCP) Tissue Sampling for the Diagnosis of Suspected Pancreatico-Biliary Cancer
The two most commonly used methods to biopsy suspected pancreaticobiliary masses are (1) endoscopic ultrasound guided fine-needle aspiration (EUS-FNA) and (2) cytology brush biopsies obtained during endoscopic retrograde…
- Conditions
- Pancreaticobiliary Cancers, Jaundice, Bile Duct Obstruction
- Trial name
- NCT01356030
- Testing
- ERCP, EUS FNA
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- California Pacific Medical Center Research Institute
Pancreatic Tumor
Evaluation of EUS-Guided 22 Gauge Core Biopsy Versus Fine-needle Aspiration for Suspected Pancreatic Neoplasms
We aim to compare the efficacy (diagnostic yield), ease of use, and technical success rates of EUS guided 22 gauge fine needle aspiration to core biopsy in the evaluation of pancreatic tumors.
- Trial name
- NCT01673334
- Testing
- Fine Needle Aspiration (FNA) and Core biopsy (FNB)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Virginia
Klatskin Tumor, Cholangiocarcinoma
Diagnostic Efficacy of EUS-FNA/B Versus ERCP With or Without POCS-TB in Patients With Suspected Hilar Cholangiocarcinoma
This is an observational study with a prospective cohort design. This study enrolled patients with suspected hilar cholangiocarcinoma on imaging.
- Conditions
- Klatskin Tumor, Cholangiocarcinoma, Biopsy, Fine-Needle, Endoscopic Retrograde Cholangiopancreatography
- Trial name
- NCT05993429
- Testing
- The sampling method selected in patients with suspected hilar cholangiocarcinoma
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Qilu Hospital of Shandong University
Solid Tumor
MOSE to Improve the Diagnostic Accuracy During EUS-guided FNA Using a 19-gauge Needle for Solid Lesions
The technique of macroscopic on-site evaluation (MOSE) has recently been advocated for estimating the adequacy of a core specimen for histological diagnosis during EUS-FNA using a 19-gauge needle.
- Trial name
- NCT03130140
- Testing
- Macroscopic on-site evaluation, Control
- Where
- Hong Kong
- Volunteers
- 244 people
- Sponsor
- Chinese University of Hong Kong
Fibrosis
Comparison of EUS-Guided Liver Biopsy With Percutaneous Liver Biopsy
There are several ways to perform liver biopsies, including the percutaneous route (historical gold standard) and via endoscopic ultrasound (EUS) guidance.
- Trial name
- NCT02947516
- Testing
- Endoscopic ultrasound-guided liver biopsy, Percutaneous liver biopsy
- Sponsor
- Brigham and Women's Hospital
Autoimmune Pancreatitis
Diagnostic Yield of FNA Needle and FNB Needle for Autoimmune Pancreatitis
The aim of this study is to compare the diagnostic accuracy of two EUS-guided tissue acquisition devices; the 19G Echotip Ultra Fine Needle Aspiration (FNA) device and the 20G Echotip ProCore Fine Needle Biopsy (FNB) device for…
- Trial name
- NCT03753815
- Testing
- 19G FNA needle, 20G FNB needle
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Peking Union Medical College Hospital
Fine Needle Aspiration, Pancreatic Mass
EUS FNB Versus FNA With On-Site Cytopathology in Solid Pancreatic Masses
The objective of this paired cohort study is to evaluate the diagnostic accuracy of Endoscopic Ultrasound-fine needle aspiration (EUS-FNA) with rapid onsite evaluation (ROSE) compared to EUS-fine needle biopsy (EUS-FNB) without…
- Trial name
- NCT03485924
- Testing
- EUS-FNA with ROSE, EUS-FNB without ROSE
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Johns Hopkins University
GI Cancer
Macroscopic on Cite Evaluation of EUS-FNA Specimen With 22 G Needle
In order for the diagnosis of digestive system tumors and their appropriate treatment afterward, the type of these tumors should be determined by the pathologist.
- Trial name
- NCT04774679
- Testing
- Endosonographic fine needle aspiration biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kocaeli University
Pancreatic Cysts
Registry and Fluid Banking of Pancreatic Cystic Lesions
The purpose of this study is to follow patients, who have small mucinous cysts in the pancreas, prospectively over a 5-year period.
- Trial name
- NCT01769534
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Efficacy, Self
Diagnostic Efficacy Of 3 EUS-FNB Techniques
Endoscopic ultrasound (EUS) is a widely recognized tool for over 30 years for diagnosing intra-abdominal lesions and gastrointestinal cancers, especially pancreatic neoplasia.
- Trial name
- NCT05825729
- Testing
- Dry suction technique (A), Slow-pull technique (B), Wet suction technique (C)
- Where
- 2 sites in Spain
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Insular Gran Canaria
Cancer, Infection
Comparison of "Wet Suction" Technique to Contemporary "Dry Suction" Technique Using a 22 Gauge Needle for EUS FNA
ROLE OF SUCTION IN EUS-FNA: Current suction technique involves suctioning the aspirate into the needle that has an air column. The needle is not flushed with any liquid prior to passing into the desired solid lesion.
- Conditions
- Cancer, Infection, Inflammation, Tumor
- Trial name
- NCT01720745
- Where
- 2 sites in United States
- Volunteers
- 128 people
- Sponsor
- University of Minnesota
Biopsy, Fine-needle, Pancreatic Neoplasm
EUS-FNB for Solid Pancreatic Lesions: Side-fenestrated Vs Fork-tip Needle
Rationale: Until now there are no prospective studies comparing the 22 gauge and 25 gauge side-fenestrated and fork-tip needles.
- Trial name
- NCT03622229
- Testing
- Histologic evaluation
- Where
- 2 sites in Italy
- Volunteers
- 192 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
EUS-FNA, Rectal Cancer
TRUS-FNA For The Prediction Of pCR After Neoadjuvant Treatment In Rectal Cancer
Colorectal cancer is one of the most malignancies worldwide. The dominant clinical research strategy of LARC includes neoadjuvant chemoradiotherapy before radical surgery followed combined with adjuvant treatment.
- Conditions
- EUS-FNA, Rectal Cancer, Pathological Complete Remission
- Trial name
- NCT04939103
- Testing
- TRUS-FNA
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Pancreatic Tumor, Fine Needle Aspiration
Comparison of Two Needles (ProCore vs EchoTip) for the Diagnosis of Pancreatic Solid Mass Under EUS
The negative predictive value of fine needle aspiration under ultrasound endoscopy (EUS) for the diagnostic of solid pancreatic masses is 70% on average in the current literature with 22 gauge needles.
- Conditions
- Pancreatic Tumor, Fine Needle Aspiration, Endoscopic Ultrasonography
- Trial name
- PICORE (NCT01479803)
- Testing
- Puncture with fine needle aspiration under endoscopic ultrasonographic control
- Where
- France
- Volunteers
- 80 people
- Sponsor
- VANBIERVLIET
Pancreas Neoplasms
Comparing of a 22G EUS Procore Fine Needle Biopsy Device and a 20G EUS Procore Fine Needle Biopsy Device
The purpose of this study is to compare the diagnosis accuracy of 22G EUS Procore fine needle biopsy （FNB）device and 20G EUS Procore fine needle biopsy device for solid pancreatic lesions.
- Trial name
- NCT03803930
- Testing
- Using 22G FNB, the first pass is SP, Using 22G FNB, the first pass is MWST, Using 20G FNB, the first pass is SP
- Where
- China
- Volunteers
- 1,224 people
- Sponsor
- Huazhong University of Science and Technology
Pancreatic Cancer
Evaluating the Number of Passes Required for Diagnostic Cell Block During EUS-FNA of Solid Pancreatic Mass Lesions
This study will test the amount of tissue, called "cell block", obtained from your pancreas. Patients who are asked to participate in this study have a growth (mass) in the pancreas that needs a biopsy so a diagnosis can be made.
- Trial name
- NCT01809028
- Testing
- EUS FNA with 2 passes, EUS FNA with 4 passes
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- AdventHealth
Pancreas Adenocarcinoma
Establishment of Pancreas Cancer and Cancer-associated Fibroblast Using EUS-guided Biopsy Samples
Organoid has emerged as the novel platform for preclinical anticancer drug testing in pancreatic ductal adenocarcinoma (PDA). However, most organoid models are not reconstituted with a tumor microenvironment.
- Trial name
- NCT05571956
- Testing
- Pancreatic ductal adenocarcinoma organoids and cancer-associated fibroblasts establishment group
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Ajou University School of Medicine
Pancreatic Neoplasms
Comparative Study of 22 and 25 Gauge ProCore EUS-guided Biopsy in Pancreatic Mass
Background: EUS-guided fine needle aspiration (FNA) is a major diagnostic tool in the patient with pancreatic mass with high specificity, specificity and accuracy.
- Trial name
- NCT01727921
- Testing
- 22 gauge ProCore needle biopsy, 25 gauge ProCore needle biopsy
- Where
- South Korea
- Volunteers
- 219 people
- Sponsor
- Samsung Medical Center