Clinical trials: Early Cancer Detection
Breast Cancer
Inpatient Screening Mammography for Non-adherent and High Risk Women
The investigators propose to pilot a program that will evaluate the feasibility of an inpatient screening mammography for non-adherent and high risk hospitalized women age 52-74 admitted to the medicine services at Johns Hopkins…
- Trial name
- NCT04164251
- Testing
- Screening mammography
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Colorectal Cancer Screening
An Interactive Preventive Health Record to Increase Colorectal Cancer Screening
This study involves 3 phases that modifies current Interactive Preventative Health Record-Colorectal Cancer Screening (IPHR-CRCS) modules to address each patient's individual colorectal cancer screening (CRCS) knowledge…
- Trial name
- MyCRCS (NCT01885351)
- Testing
- MyCRCS+Prefs, MyCRCS+Prefs+Barriers
- Where
- 2 sites in United States
- Volunteers
- 683 people, healthy volunteers welcome
- Sponsor
- Temple University
Colorectal Carcinoma
Educational Intervention - Improving Knowledge and Screening Rates for Colorectal Cancer
This clinical trial studies how well educational intervention works in improving knowledge and screening rates of colorectal cancer.
- Trial name
- NCT03287453
- Testing
- Educational Intervention, Survey Administration
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cervix Cancer, Screen HPV-positive
Uniting Trusted Community Messengers to Improve Access to Cervical Cancer Screening in Rural North Carolina
The purpose of this study is to test the feasibility and acceptability of a multi-level, community-engaged intervention to increase access to cervical cancer screening using human papillomavirus (HPV) self-collection (HPVSC)…
- Trial name
- NCT07294066
- Testing
- Human papilloma virus screening
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Pancreatic Cancer, Chronic Pancreatitis
Biospecimens for Identification of Diseases of the Pancreas.
This proposed project is designed to collect data and specimens from patients/subjects presenting to the University of Michigan with a disease affecting the pancreas (or specific control populations).
- Conditions
- Pancreatic Cancer, Chronic Pancreatitis, Type II Diabetes, Pancreatic Cysts
- Trial name
- SPORE-PANC (NCT01392027)
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 712 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Prostate Cancer
Combined Prostate-specific Antigen, Multi-parametric MRI and Targeted Prostate Biopsy for Prostate Cancer Screening
The study aims to investigate the incidence of prostate cancer among males in Nanjing and whether a combination of PSA, multi-parametric MRI and targeted biopsy is a feasible approach for screening prostate cancer in China.
- Trial name
- NCT04322045
- Testing
- multi-parametric MRI
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Breast Neoplasms, Early Detection of Cancer
Breast Ultrasound Screening in Elderly Women: A Multicenter Cluster Randomized Trial
This multicenter, cluster randomized trial will evaluate whether community-based breast ultrasound screening improves the early detection of breast cancer in women aged 65 to 80 years, compared with routine health management.
- Trial name
- NCT07698366
- Testing
- Standardized Breast Ultrasound Screening
- Where
- 2 sites in China
- Volunteers
- 80,000 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Health Behavior
Digital Detox Study: A Randomized Controlled Trial
The aim of the present RCT is to investigate the effect of smartphone screen time reduction on mental health indicators in healthy, 18-29 yo Austrian students.
- Trial name
- NCT06353451
- Testing
- Digital Detox
- Where
- Austria
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Danube University Krems
Hepatocellular Carcinoma
Refinement and Validation of a Diagnostic Model (GAMAD) for Early Detection of Hepatocellular Carcinoma
Most hepatocellular carcinoma (HCC) cases were at advanced stage when diagnosis established. This study is intended to establish a clinical diagnostic model GAMAD for early-stage HCC and evaluate the diagnostic efficiency the…
- Trial name
- NCT05626985
- Testing
- GAMAD
- Where
- 3 sites in China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Singlera Genomics Inc.
Colorectal Cancer, Colorectal Neoplasms
Evaluation of a Model for the Early Diagnosis of Colorectal Cancer by the Detection of 5-hydroxymethylcytosine (5-hmC) in Plasma Cell-free DNA to the Community Colorectal Cancer Screening Program
The incidence rate and mortality of colorectal cancer are increasing year by year. Most colorectal cancer develops from colorectal adenoma and is a disease that can be prevented and controlled.
- Trial name
- METHOD-3 (NCT05638243)
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Fudan University
Intracranial Tumors
AssesSment of Early deteCtion basEd oN liquiD Biopsy in Intracranial Tumors
ASCEND-BRAIN is a prospective, observational study aimed at early-detection of intracranial tumors by combined assays of cfDNA methylation and other biomarkers.
- Trial name
- ASCEND-BRAIN (NCT05679089)
- Testing
- early detection test
- Where
- China
- Volunteers
- 358 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Colon Cancer Screening, Healthy Person
PROgastrine COlon DEpistage
Dosage of progastrin in asymptomatic person participating in colon cancer screening
- Trial name
- NCT03775473
- Testing
- progastrin
- Where
- France
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- ECS-Progastrin SA
Depression
Validating the Patient Health Questionnaire in Pregnant and Post-partum Migrant Women
The objective of this study is to validate the Patient Health Questionnaire-9 (PHQ-9) and the Refugee Health Screener-15 (RHS-15) screening tools for depression in pregnant and post-partum migrant women on the Thai-Myanmar border.
- Trial name
- NCT02790905
- Where
- Thailand
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Lung Cancer Prevention
Mobile Lung Cancer Screening
Lung cancer screening using low-dose CT (LDCT) has been shown to reduce mortality in high-risk populations. In 2022, the French National Cancer Institute (INCa) issued guidelines recommending screening for individuals aged 50-74…
- Trial name
- MobILYAD (NCT07015151)
- Testing
- Low-dose Chest CT Screening, Spirometry, Cardiovascular Risk Assessment
- Where
- 2 sites in France
- Volunteers
- 4,312 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Cancer, Early Detection of Cancer
Caris Biorepository Research Protocol
The Biorepository for Caris Life Sciences is designed for the purpose of making quality biospecimens and associated clinical data available for research studies related to advancing precision medicine and improving care for…
- Conditions
- Cancer, Early Detection of Cancer, Minimal Residual Disease
- Trial name
- NCT01499394
- Where
- 38 sites in United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Caris Science, Inc.
Diabetic Neuropathies, Diabetic Foot
Thermal Screening for Early Diabetic Peripheral Neuropathy (DPN)
The goal of this research is to develop better tools for diagnosing illness of the feet and legs of people who have diabetes. Investigators will use thermal videos of the foot to aid in the refinement of a system designed to…
- Conditions
- Diabetic Neuropathies, Diabetic Foot, Diabetic Retinopathy
- Trial name
- NCT03069729
- Testing
- no intervention
- Where
- United States
- Volunteers
- 331 people, healthy volunteers welcome
- Sponsor
- VisionQuest Biomedical LLC
Breast Cancer Screening, Colon Cancer Screening
Evaluating the Shared Decision Making Process Scale in Cancer Screening Decisions
The purpose of this retrospective observational study is to evaluate the performance of the Shared Decision Making Process scale in a sample of patients who have received a decision aid about the decision to screen or not screen…
- Conditions
- Breast Cancer Screening, Colon Cancer Screening, Prostate Cancer Screening
- Trial name
- NCT04601272
- Testing
- Decision aid
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Smoking, Smoking, Cigarette
The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study
Mobile health (mHealth) will be used for early detection of oral cancer and pre-cancer lesions, and to improve awareness of oral cancer among the population and knowledge of oral cancer diagnosis among frontline health providers.
- Conditions
- Smoking, Smoking, Cigarette, Smoking, Tobacco, Betel Chewer's Mucosa
- Trial name
- NCT06535867
- Testing
- mHealth
- Where
- United States
- Volunteers
- 5,122 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cancer, Lung Cancer
The SUMMIT Study: A Cancer Screening Study
The SUMMIT Study will enrol 13,000 participants in order to investigate how cancer screening can be improved and delivered. The SUMMIT Study has two main aims: the first is to clinically validate a blood test for detecting…
- Trial name
- SUMMIT (NCT03934866)
- Testing
- Low Dose CT scan
- Where
- United Kingdom
- Volunteers
- 13,035 people, healthy volunteers welcome
- Sponsor
- University College, London
Hepatitis C Virus Infection, Colorectal Cancer
CARES-HCV: Promoting Screening Uptake Among Diverse Baby Boomers
The purpose of the study is to examine the efficacy of educational materials to promote hepatitis C virus (HCV) screening and colorectal cancer (CRC) screening uptake among adults born between 1945-1965.
- Trial name
- NCT04980157
- Testing
- CARES-HCV
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
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