Clinical trials: Early Cancer Detection
Neoplasm
Cancer in the Small Developing Island States of the Eastern Caribbean
Caribbean studies examining overseas cancer care were lacking patient-level data. Investigators will collect data from patients by establishing a cohort of survivors across six small island developing states (SIDS) (Antigua…
- Trial name
- CaSIDEC (NCT07695116)
- Testing
- Overeseas travel for care
- Where
- 6 sites in Antigua and Barbuda, Dominica and 4 more
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Vaughan A. Lewis Institute for Research and Innovation
Breast Carcinoma
Breast Cancer Screening Adherence for Women at Moderate Risk for Breast Cancer
This study assesses breast cancer screening adherence for women at moderately increased risk for developing breast cancer based on gene mutation status or empiric risk model estimates.
- Trial name
- NCT07076147
- Testing
- Non-Interventional Study
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Breast Neoplasms
The Tomosynthesis Trial in Bergen - Part 2
The aim of the study is to compare early performance measures and economic aspects of organized breast cancer screening for women screened using digital breast tomosynthesis+synthetic mammography (DBT+SM) to women with a prior…
- Trial name
- To-Be 2 (NCT03669926)
- Testing
- Digital Breast Tomosynthesis+synthetic mammography
- Where
- Norway
- Volunteers
- 31,082 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Cervical Cancer
Cervical Cancer Screening Among Hispanic Women
In this study, 400 Hispanic women will be recruited and randomized to one of three interventions: 1. Control (no change); 2. A low-intensity information program, consisting of a video approach educating women on the importance of…
- Trial name
- NCT01525433
- Testing
- DVD, Promotora
- Where
- United States
- Volunteers
- 451 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Fecal Immunochemical Test
Efficacy of Fecal Immunochemical Test Using Digital Rectal Exam
This study will investigate the use of digital rectal exam (DRE) to obtain stool samples for the fecal immunochemical test (FIT) in patients due for screening colonoscopy and in pre-operative patients with known colorectal…
- Trial name
- FIT-DRE (NCT03013855)
- Testing
- FIT-SOC, FIT-DRE
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
The Aim of the Study Was to Screen Prevalence of Periodic Limb Movements Among Chronic Kidney Disease Patients
Periodic Limb Movements Among Dialysis and Non-dialysis Chronic Kidney Disease Patients
Periodic leg movement disorder is defined as periodic episodes of repetitive limb movements during sleep that mainly occur in the lower limb, including the hips, knees and toes and sometimes affects the upper limb.
- Trial name
- NCT05153616
- Testing
- Polysomnography
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aswan University Hospital
Brain Tumor, Brain Edema
The Accuracy of Brain Biological Electrical Impedance Tomography Screen for Supratentorial Tumors
Compared with MRI or CT, brain biological electrical impedance tomography were performed on patients with supratentorial tumors and healthy people .
- Trial name
- ABST (NCT04490954)
- Testing
- brain biological electrical impedance tomography, MRI/CT
- Where
- China
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Colorectal Neoplasms
Interventions to Improve Colorectal Cancer Screening
We will evaluate if we can increase colorectal cancer screening rates by directly sending screening tests to patients rather than waiting for them to come to clinic visits.
- Trial name
- NCT00692211
- Testing
- Mailed fecal occult blood tests, Mailed fecal immunochemical tests
- Where
- United States
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Cervical Cancer Screening
Addressing Stigma in Screening and Diagnostic Delay for Cervical Cancer
This study aims to 1) implement a culturally and contextually rooted innovative multifoci, social marketing intervention involving societal focused media campaign elements to break down the barriers and facilitate timely and…
- Trial name
- NCT01287871
- Testing
- supportive care
- Where
- United States
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Lung Cancer Screening
Community-Based Engagement to Improve Lung Cancer Screening and Outcomes: The "Our Lungs Our Health" Study
The main goal of this pilot study is to understand the impact of a mobile lung cancer screening clinics in individuals from neighborhoods and communities with less access to resources in Boston, Massachusetts who are at high risk…
- Trial name
- NCT06909981
- Testing
- Low-Dose Computed Tomography Scan
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Screening Mammogram
Increasing Breast Cancer Screening in Chinese Immigrants
The long-term goal of this research is to increase breast cancer screening rates in NYC Chinese immigrants. The researchers plan to accomplish this objective by developing and testing a culturally- and linguistically-adapted…
- Trial name
- NCT05089292
- Testing
- Narrative breast health education
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cancer
LEVANTIS-0093A: GAGomes for Multi-Cancer Early Detection in High-Risk Adults (LEV93A)
LEVANTIS-0093A (LEV93A) is a prospective cohort observational clinical study to validate the plasma free GAGome MCED test in adults at high risk of developing cancer ("high-risk adults"), specifically in 55-80-year-old adults…
- Trial name
- LEV93A (NCT05295017)
- Where
- United Kingdom
- Volunteers
- 1,235 people, healthy volunteers welcome
- Sponsor
- Elypta
Artificial Intelligence, Deep Learning
Artificial Intelligence System for Assessment of Tumor Risk and Diagnosis and Treatment
To improve the accuracy of risk prediction, screening and treatment outcome of cancer, we aim to establish a medical database that includes standardized and structured clinical diagnosis and treatment information, image features…
- Conditions
- Artificial Intelligence, Deep Learning, Lung Cancer, Lung; Node
- Trial name
- NCT05426135
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Breast Cancer
Assessment of Feasibility and Acceptability of Personalized Breast Cancer Screening
The overall objective is to assess the acceptability and feasibility of offering personalized breast cancer (BC) screening. The specific objectives are: 1) To design an information system; 2) To evaluate the barriers and…
- Trial name
- DECIDO (NCT03791008)
- Testing
- Risk based screening
- Where
- Spain
- Volunteers
- 387 people, healthy volunteers welcome
- Sponsor
- Institut de Recerca Biomèdica de Lleida
Breast Carcinoma
MammoScreen Breast Cancer Risk Assessment and Decision Aid for Breast Cancer Screening and Referrals
This study collects information to implement MammoScreen for Breast Cancer Screening and Referrals. MammoScreen is a risk assessment questionnaire that identifies individuals at average and increased risk for breast cancer and…
- Trial name
- NCT04996316
- Testing
- Electronic Health Record Review, Interview, Media Intervention
- Where
- United States
- Volunteers
- 1,141 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Asymptomatic
Abbreviated Breast MRI and Digital Tomosynthesis Mammography in Screening Women With Dense Breasts
This randomized phase II trial studies how well abbreviated breast magnetic resonance imaging (MRI) and digital tomosynthesis mammography work in detecting cancer in women with dense breasts.
- Trial name
- NCT02933489
- Testing
- Contrast-enhanced Magnetic Resonance Imaging, Digital Tomosynthesis Mammography, Quality-of-Life Assessment
- Where
- 68 sites in United States, Germany
- Volunteers
- 1,516 people, healthy volunteers welcome
- Sponsor
- ECOG-ACRIN Cancer Research Group
Syndrome
Comprehensive Validation of Frailty Assessment Tools in Older Adults in Different Clinical and Social Settings
There is a proved strong evidence of the usefulness of frailty as a predictive factor of relevant and desired outcomes in populations of older adults.
- Trial name
- FRAILTOOLS (NCT02637518)
- Testing
- Assessment of frailty tools in elderly people
- Where
- Spain
- Volunteers
- 1,940 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Getafe
Sleep, Circadian Rhythm
SCREENS: Sleep, Circadian Rhythms, and Electronics in the EveNing Study
The proposed project aims to disentangle the impact of evening light exposure emitted from tablet devices from the impact of arousing media content on children's sleep regulation, circadian physiology and next-day emotion…
- Conditions
- Sleep, Circadian Rhythm, Executive Function, Emotion Regulation
- Trial name
- SCREENS (NCT06192745)
- Testing
- no screen control with dim light and calming activities, unfiltered Bright tablet screen, Filtered dim tablet screen
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Prostate Cancer
Prostate Cancer Awareness and Initiative for Screening in the European Union
PRAISE-U was initiated on the 1st of April 2023 and is set to last for three years. This collaborative effort involves 25 institutions across 12 countries, all driven by a shared objective: to rationalize prostate cancer…
- Trial name
- PRAISE-U (NCT06424275)
- Testing
- Risk-based screening algorithm
- Where
- 5 sites in Ireland, Lithuania and 2 more
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- European Association of Urology Research Foundation
Health Information Avoidance
Interventions to Decrease Health Information Avoidance
Health information avoidance is an overlooked threat to the reach and effectiveness of health communication. To fully realize the benefits of our sizeable investments in health messaging, it is necessary to identify strategies…
- Trial name
- NCT06972667
- Testing
- Video to promote colonoscopy, Video to promote screening for colorectal cancer with home tests
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
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