Clinical trials: Early Cancer Detection
Breast Cancer Female, Colorectal Cancer
Increasing Colorectal and Breast Cancer Screening in Women
This study compares the efficacy (adherence and stage) of four interventions to promote colorectal (CRC) and breast cancer (BC) screenings among women ages 50 to 75. They are: 1. usual care; 2.
- Trial name
- COBRA (NCT03279198)
- Testing
- TIWeb, CSC, UC
- Volunteers
- 1,196 people, healthy volunteers welcome
- Sponsor
- Indiana University
Genital Human Papilloma Virus Infection
A Model for Implementation of Cervical Cancer Screening and HPV Vaccination the Emergency Department: a Pilot Study
In this pilot study, we intend to demonstrate that a great portion of women at high risk (inadequate screening, HPV 16/18 and/or cytology) are presenting to the ED, cytology/ HPV testing via ThinPrep®Pap testTM and surveillance.
- Trial name
- NCT01133509
- Testing
- Gardasil
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Colonoscopy, Colorectal Cancer Screening
Robotic Colonoscopy Using the Triton 4.0 System in Adults for Screening, Surveillance, and Diagnosis of Lower Gastrointestinal Conditions
This study is a prospective, single-arm, non-randomized, single site first-in-human study and will be conducted in two phases, where Phase A will serve to evaluate the safety of the Triton 4.0 System to perform screening…
- Conditions
- Colonoscopy, Colorectal Cancer Screening, Colorectal Neoplasms, Gastrointestinal Endoscopy
- Trial name
- CARE I (NCT06935734)
- Testing
- Diagnostic Colonoscopy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Neptune Medical
Colorectal Neoplasms, Intestinal Neoplasms
Usefulness of GI-GENIUS in FIT-based Colorectal Cancer Screening Program.
Deep learning technology has an increasing role in medical image applications and, recently, an artificial intelligence device has been developed and commercialized by Medtronic for identification of polyps during colonoscopy…
- Conditions
- Colorectal Neoplasms, Intestinal Neoplasms, Gastrointestinal Neoplasms, Colonic Polyp
- Trial name
- CADILLAC (NCT04673136)
- Testing
- GI-GENIUS Medtronic, Colonoscopy
- Where
- 6 sites in Spain
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- Asociación Española de Gastroenterología
Colorectal Cancer
Effectiveness of Tel and SMS Reminder on Compliance With CRC Screening
Colorectal cancer (CRC) is one of the major global health challenges. CRC is currently the third most common cancer in men and the second common in women worldwide, accounting for approximately 10% of all cancers.
- Trial name
- NCT02815436
- Testing
- Telephone reminder, SMS reminder
- Where
- Hong Kong
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Mammography, Breast Cancer
Searching for Masses and Calcifications at the Same Time in Breast Cancer Screening
Brief Summary A task like breast cancer screening (mammography) can be described as a "hybrid search" task. In basic visual search tasks, observers search for a target among distractors that are not the target.
- Conditions
- Mammography, Breast Cancer, Radiology
- Trial name
- NCT05975736
- Testing
- Search only for masses, Search only for calcifications, Search for both together
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Cancer
Multi-Cancer Early Detection (MCED) of Firefighters
This study is an an observational prospective cohort research study to explore the performance of new blood and urine tests for the early detection of cancer among firefighters.
- Trial name
- NCT05780957
- Testing
- MCED
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Vincere Cancer Center
Colorectal Cancer
Comparing Interventions to Increase Colorectal Cancer Screening
The purpose of this study is to test different approaches to help people understand the purpose of colorectal cancer (CRC) screening, two screening test options available, and the barriers to screening so they can make informed…
- Trial name
- NCT03200366
- Testing
- Tailored DVD, Patient Navigation
- Where
- 2 sites in United States
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- Indiana University
Eating Behavior
Healthy Online Parental Education Project to Increase Fruit and Vegetable Intake and Active Playtime Among Toddlers
The research proposal will be an 8-week randomized control trial (RCT) to examine the efficacy of an eHealth intervention, namely Healthy Parental Online Education (HOPE), on fruit and vegetable intake and active playtime among…
- Trial name
- HOPE (NCT05085041)
- Testing
- Multi-Component eHealth Intervention, namely Healthy Online Parental Education (HOPE)
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Lung Cancer
Early Stage Lung Cancer Screening With Low-dose Computed Tomographic
The present study is a randomized controlled trial of LDCT screening for lung cancer versus usual care. 6000 high-risk subjects (age 45-70) were recruited and randomized to the Active arm (Baseline + 2 biennial repeated LDCT…
- Trial name
- NCT02898441
- Testing
- Low Dose Computed Tomography
- Where
- China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Chest Hospital
Healthy Volunteers
Comparison of Explicit, Implicit and no Values Clarification Decision Aids for Men Considering Prostate Cancer Screening
The investigators aim at comparing the perceived clarity of personal values in men considering PSA screening using decision aids with no VCM versus an implicit VCM versus an explicit VCM.
- Trial name
- NCT03988673
- Testing
- Decision aid with implicit values clarification method (booklet or website), Decision aid with explicit values clarification method (booklet or website)
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Cervical Intraepithelial Neoplasia, Cervical Cancer (Early Detection)
Cervical Intraepithelial Neoplasia Screening Using Liquid-Based Pap Smear Among Egyptian Women
This observational study aims to screen Egyptian women aged 25-60 for cervical intraepithelial neoplasia (CIN) using liquid-based Pap smear during routine gynecological visits at Kasr Al-Aini outpatient clinics.
- Trial name
- NCT07250841
- Testing
- Liquid-Based Pap Smear (LBC)
- Where
- Egypt
- Volunteers
- 984 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Human Papillomavirus 16, Human Papillomavirus 18
Integrated Cervical Cancer Screening in Mayuge District Uganda (ASPIRE Mayuge)
The purpose of this pragmatic cluster randomized control trial is to test the effectiveness of cervical cancer screening follow-up completion using two implementation approaches for self-collected HPV testing in a rural…
- Conditions
- Human Papillomavirus 16, Human Papillomavirus 18, Papillomavirus Infections, Cervical Cancer
- Trial name
- ASPIRE (NCT04000503)
- Testing
- Self-collected HPV testing for cervical cancer screening
- Where
- Uganda
- Volunteers
- 2,019 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Childhood Obesity
Physical Activity and Screen-Time Regulations in Childcare Centers - Aim 1
The goal of this project is to examine the physical activity and screen-time environment of licensed childcare centers before and after the enactment of new state regulations.
- Trial name
- Pause and Play (NCT02751788)
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Colorectal Carcinoma
A Multilevel Approach for Improvement in Screening of Colorectal Cancer in Rural Communities, The Screen to Save Trial
This clinical trial determines the feasibility of a multilevel approach to improve colorectal cancer screening within two rural regions of the Fred Hutchinson Cancer Research Center/University of Washington Consortium catchment…
- Trial name
- NCT05291988
- Testing
- Educational Intervention, Fecal Immunochemical Test, Questionnaire Administration
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Lung Cancer, Chronic Obstructive Airway Disease
Early Detection of Lung Tumors by Sniffer Dogs - Evaluation of Sensitivity and Specificity
Some groups reported that sniffer dogs can be applied to detect lung cancer in the exhaled breath of patients. Therefore, breath samples (BS) of patients are collected.
- Trial name
- NCT01141842
- Testing
- exhalation analysis of breath sample
- Where
- 2 sites in Germany
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Schillerhoehe Hospital
Cancer, Healthy Participants
Prospective Study for the Development, Validation and Confirmation of a Multi-Cancer Early Detection Platform Through Whole-Genome Sequencing Analysis of Circulating DNA in Cancer and Non-Cancer Subjects
This is a prospective, multi-center clinical study of Multi-Cancer Early Detection (MCED) testing in cancer patients and healthy volunteers.
- Trial name
- NCT07598747
- Where
- South Korea
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Chang Gon Kim
Cervical Cancer Screening
Breast Cancer-Related Approach for Increasing Cervical Cancer Screening
The primary objective of this clinical trial is to assess cervical cancer screening participation among under-screened women invited through organized breast cancer screening programs in Switzerland.
- Trial name
- BRAICS (NCT07171658)
- Testing
- Sensitization to Cervical Cancer (CC) screening, Home-based HPV self-sampling
- Where
- Switzerland
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Jessica Di Vincenzo Sormani
Colorectal Neoplasm, Colonic Polyps
Clinical Study of Real Time Colorectal Polyp Diagnosis During Colonoscopy - the VALID Colonoscopy Study
The investigators hypothesize that high definition colonoscopy with close focus narrow band imaging features has a high diagnostic accuracy for colorectal polyp histology, and can replace formal pathologic assessment in cases of…
- Trial name
- VALID (NCT01288833)
- Testing
- Close focus HD NBI Colonoscopy System
- Where
- 2 sites in United States
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Colorectal Cancer Screening
Pilot Testing of a Colorectal Cancer Education Program
The primary objective of this study is to assess the feasibility, acceptability, and preliminary efficacy of a culturally and linguistically targeted, colorectal cancer (CRC) education program to improve CRC screening completion.
- Trial name
- NCT07361614
- Testing
- Educational Program
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
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