Clinical trials: Early Childhood
Early Life Adversity, Chronic Stress
Health Experiences & Early Life Disadvantages
Growing up in a low-income household has been shown to increase risk for, and susceptibility to many illnesses.The purpose of the study is to test an affective intervention for reversing biological risk factors, as related to…
- Trial name
- HEELD (NCT02400593)
- Testing
- Meditation Workshop
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Mental Health, Child Development
Caregiver Mental Health and Early Childhood Development in Conflict-Affected Settings
The goal of this clinical trial is to learn if a community-based psychosocial program can improve caregivers' mental health and support the healthy development of young children in communities affected by conflict and forced…
- Conditions
- Mental Health, Child Development, Relationships, Father-Child
- Trial name
- NCT07148531
- Testing
- Seeds for Attachment (translated version)
- Where
- 12 sites in Colombia
- Volunteers
- 2,348 people, healthy volunteers welcome
- Sponsor
- University of Los Andes, Columbia
Violence, Gender-Based, Violence, Domestic
Responsible Engaged and Loving (REAL) Fathers Intervention Evaluation
The goal of this stepped-wedge cluster randomized control trial is to assess whether a Ugandan community-based intervention for young fathers (ages 18-25 years) of children ages 0-3 years impacts fathers' knowledge, attitudes…
- Conditions
- Violence, Gender-Based, Violence, Domestic, Violence, Sexual, Violence, Physical
- Trial name
- NCT06100679
- Testing
- Responsible Engaged and Loving (REAL) Fathers Initiative
- Where
- 4 sites in Uganda
- Volunteers
- 4,728 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
IUGR, Fetal Growth Retardation
Cardiac Displacement From Third Trimester to Early Childhood
The aim is to increase awareness of the relationship between (IUGR) and cardiac function in the foetus, the development of cardiac function over time after delivery and what significance a possible early disturbed myocardial…
- Conditions
- IUGR, Fetal Growth Retardation, Intrauterine Growth Restriction
- Trial name
- CADETTE (NCT02583763)
- Testing
- Echocardiography, Blood sample
- Where
- 2 sites in Sweden
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Healthy
FoodStep - a Sustainable Model for Food Services and Early Childhood Education and Care
Transformation towards a more climate-friendly and healthy sustainable diet will require major changes in the food system: increase in consumption of plant-based foods and only moderate consumption of animal-based foods.
- Trial name
- NCT05249946
- Testing
- FoodStep - a sustainable health-promoting model for food services and early childhood education and care
- Where
- Finland
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Suvi Virtanen
Early Child Development and Growth
The Pakistan Early Childhood Development Scale Up Trial
The purpose of this study is to evaluate whether the integration of an early child 'stimulation and care for development' intervention, either alone or in combination with an 'enhanced care for nutrition' intervention, delivered…
- Trial name
- PEDS (NCT00715936)
- Testing
- Control, ECD, Enhanced Nutrition
- Where
- Pakistan
- Volunteers
- 1,489 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Cognitive Developmental Delay
Neurocognitive Follow-Up (FU) Study
This is a follow-up study of a recently completed trial (17.14.INF) evaluating the growth of pre-term infants. Enrolled children will undergo neurocognitive assessments at 18- and 24-months of corrected age (CA).
- Trial name
- NCT04962035
- Testing
- Neurocognitive Follow-up
- Where
- 3 sites in Poland, Slovakia
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Cognitive Change
COgnitive Dynamics in Early Childhood
The goal of this accelerated longitudinal observational cohort study is to advance our understanding of cognitive variability in children aged 7 to 10 at first measurement.
- Trial name
- CODEC (NCT06330090)
- Where
- Netherlands
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
ECC, LBW Children
Association Between Early Childhood Caries, Low Birth Weight and Nutritional Risk Factors: (Cohort Study)
The aim of this study is to assess the ECC experience in children aged from 12 to 36 month with low birth weight children in comparison to normal birth weight.
- Trial name
- NCT04344366
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Evaluation of a Brief Tailored Motivational Intervention to Prevent Early Childhood Caries
The Detroit Dental Health Project (DDHP)aims to promote oral health and reduce disparities within the community of low-income African-American children (0-5 years) and their main caregivers (14+ years), living in the City of…
- Trial name
- NCT01123330
- Testing
- Motivational Interviewing
- Where
- United States
- Volunteers
- 2,042 people, healthy volunteers welcome
- Sponsor
- Temple University
Child Abuse, Parenting
Malezi Na Kilimo Bora - Skilful Parenting and Agribusiness Child Abuse Prevention Study
The Malezi ne Kilimo Bora ("Good Parenting and Farming" in Kiswahili) Skilful Parenting and Agribusiness Child Abuse Prevention Study is a collaboration between the University of Oxford, University of Glasgow, and the Tanzania…
- Trial name
- SPACAPS (NCT02633319)
- Testing
- Skilful Parenting, Agrics
- Where
- Tanzania
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Intimate Partner Violence (IPV)
Familia Imara: A Parenting Program to Reduce Family Violence in Tanzania
This cluster-randomized controlled trial will evaluate the effectiveness, implementation, and scalability of Familia Imara, a group-based, couples-focused, community health worker (CHW)-delivered parenting program, on reducing…
- Trial name
- NCT07574567
- Testing
- Familia Imara
- Where
- Tanzania
- Volunteers
- 6,216 people, healthy volunteers welcome
- Sponsor
- Saini Das
Child Development Disorder
Craniosacral Test and Primitive Reflexes in Infant Neurodevelopment
Question(s): Can active primitive reflexes (APR) and cranial blocks (CB) in healthy children interfere with neurological balance causing psycho-behavioral and cognitive dysfunctions? Design: Cross-sectional and descriptive study…
- Trial name
- NCT05190029
- Testing
- Series of questions to parents of children in a virtual form., Intervention by teachers, Physiotherapeutic evaluation
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Clinica Gema Leon
Vitamin D Deficiency
Prevalence of Early Childhood Caries in Egyptian Children With Serum Vitamin D Deficiency.
To detect the effect of vitamin D deficiency in the development of early childhood caries (ECC) among Egyptian children.
- Trial name
- NCT03158155
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Nancy Ahmed El Salmawy
Problem Behavior, Developmental Delay
Problem Behavior Assessment and Intervention in IDEA Part C Services
The purpose of this study is to evaluate the effect of function-based assessment and intervention to reduce problem behavior in children with developmental disability or delay in the context of IDEA Part C services.
- Conditions
- Problem Behavior, Developmental Delay, Developmental Disability
- Trial name
- NCT06771284
- Testing
- Function-based assessment and intervention
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Sars-CoV2, Covid-19
COPE - COVID-19 in Pregnancy and Early Childhood
Purpose: The emergence of a new coronavirus SARS-CoV-2 causing a novel infection in the human race resulting in a world-spanning pandemic came as a surprise and at a tremendous cost both for individual human lives as well as for…
- Conditions
- Sars-CoV2, Covid-19, Pregnancy Complications, Pregnancy Preterm
- Trial name
- COPE (NCT04433364)
- Testing
- biological samples, questionnaires and interviews
- Where
- 27 sites in Sweden
- Volunteers
- 3,834 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Rare Genetic Disorders, Quality of Life
The Relationship Between Functional Independence and Family Well-being in Children With Rare Genetic Disorders
This study aims to examine the psychological status and quality of life of families with children who have rare genetic disorders.
- Conditions
- Rare Genetic Disorders, Quality of Life, Functional Impairment
- Trial name
- NCT07348926
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Dyslipidemias, Children, Only
The Effect of Childhood Dyslipidemia on Endothelial and Renal Function
The aim of the study is to assess if abnormal lipid levels in childhood could cause early damage of the inner layer of the vessels, the endothelium.
- Conditions
- Dyslipidemias, Children, Only, Endothelial Dysfunction, Renal Dysfunction
- Trial name
- NCT03856476
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Ioannina
Coronavirus Infections, Gut Microbiome
The Association of Gut Microbiota With COVID 19 Infection in Children
Although COVID-19 infects gastrointestinal tissues, little is known about the roles of gut commensal microbes in susceptibility to and severity of infection.
- Conditions
- Coronavirus Infections, Gut Microbiome, Childhood ALL
- Trial name
- NCT05303155
- Testing
- 16S rRNA sequencing
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Picky Eaters, Feeding Interaction, Good Enough Parenting, Family Meals, Emotional Eating Prevention
"Improved Mother Infant Feeding Interaction (MI-FI) at 12 Months With Very Early Parent Training"
Rise in childhood obesity and poor eating habits and eating problems is apparent over the last decades. Parents are at lose what the correct way to tackle these problems may be.
- Trial name
- MI-FI (NCT03086811)
- Testing
- Mother Infant Feeding Interaction very early training
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus