Clinical trials: Early Childhood
Aging
Development and Content Validation of the Childhood Early Oral Aging Syndrome (CEOAS) Index for the Deciduous Dentition
Premature, non-physiological tooth wear in childhood has numerous repercussions for oral health. This is a growing problem with multifactorial causes and associated with the current lifestyle.
- Trial name
- NCT06378385
- Testing
- Childhood Early Oral Aging Syndrome index
- Where
- Brazil
- Volunteers
- 6 people
- Sponsor
- University of Nove de Julho
Typical Development
Promoting Motor Development in Infants and Toddlers Through Education and Early Detection
The "Little Movers" study promotes healthy motor development in early childhood by providing education to caregivers and professionals in the child's environment and by implementing early detection strategies for motor delays.
- Trial name
- Little-Movers (NCT07091474)
- Testing
- Educational Workshops for Parents and Early Educators, Motor Development Assessment in Children 0-36 Months
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Early Childhood Caries
A Clinical Trial of Silver Diamine Fluoride to Arrest Early Childhood Caries in Young Children
Silver diamine fluoride (SDF) is an antibiotic liquid that has the potential to arrest Early Childhood Caries in young children and delay treatment until children can be seen in outpatient settings.
- Trial name
- NCT04054635
- Testing
- Silver diamine fluoride
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- University of Manitoba
Adverse Childhood Experience, Endothelial Function (FMD)
Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity
Adverse childhood experiences (ACEs) represent highly stressful events in the first 18 years of life that include abuse, neglect, and household and community-level dysfunction.
- Conditions
- Adverse Childhood Experience, Endothelial Function (FMD), Endothelial Injury, Mitochondrial Function
- Trial name
- PROMISE (NCT07244809)
- Testing
- Mitoquinone mesylate (MitoQ)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Early Childhood Development (ECD)
Combined Nutrition and Parenting Study
This study aims to evaluate whether early childhood development is improved by a bundled set of interventions that promote responsive stimulation and improved nutrition by the provision of eggs and dried fish (nutrient-dense…
- Trial name
- BUNDLE (NCT07490899)
- Testing
- Responsive stimulation, female and male caregivers, Food provision and nutrition education
- Where
- 4 sites in Liberia
- Volunteers
- 2,240 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Teen Parenthood
Building Healthy Children
This study will evaluate the effectiveness of providing a combination of evidence-based behavioral health treatments for mothers who gave birth to their first child prior to the age of 21 and who meet eligibility requirements and…
- Trial name
- BHC (NCT01888809)
- Testing
- Comprehensive preventive services, Screening and referral
- Where
- United States
- Volunteers
- 1,852 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Severe Early Childhood Caries, Dental Caries
Salivary Antimicrobial Peptides and Severe Early Childhood Caries in Turkish Children
This observational study aims to evaluate the relationship between salivary antimicrobial peptides and severe early childhood caries (S-ECC) in Turkish children.
- Trial name
- NCT07414030
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Stress, Psychological, Stress, Physiological
Mindfulness Intervention for Early Childhood Educators
This is a randomized trial of the 'Cultivating Healthy, intentional, Mindful Educators' (CHIME) intervention designed for early childhood educators.
- Trial name
- CHIME (NCT04815252)
- Testing
- CHIME
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Nebraska Lincoln
Bipolar Disorder
Early Family-Focused Treatment for Youth at Risk for Bipolar Disorder
This study will test a family-based therapy aimed at preventing or reducing the symptoms of bipolar disorder in at-risk children.
- Trial name
- NCT00943085
- Testing
- Family-focused therapy, Brief educational treatment
- Where
- 2 sites in United States
- Volunteers
- 52 people
- Sponsor
- University of California, Los Angeles
Oral Health, Dental Caries
WhatsApp Messages to Improve Mothers' Oral Health Knowledge and Children's Toothbrushing
Tooth decay is one of the most common health problems in young children in Saudi Arabia. Brushing twice a day with fluoride toothpaste is one of the most effective ways to prevent it, but preschool children cannot do this…
- Conditions
- Oral Health, Dental Caries, Health Behavior, Oral Hygiene
- Trial name
- NCT07765654
- Testing
- Standardized Face-to-Face Oral Health Education, WhatsApp-Based Oral Health Messages
- Volunteers
- 106 people
- Sponsor
- King Abdulaziz University
Vegetable Acceptance in Early Childhood, Vegetable Intake
Evaluating the Implementation and Impact of an Enhanced SNAP-Ed Delivered Curriculum in Low-income Preschools
This evaluation project aims to assess the impact of the Penn State Child Health Research Center's final year of SNAP-Ed funded nutrition education program in low-income preschool classrooms in Pennsylvania.
- Conditions
- Vegetable Acceptance in Early Childhood, Vegetable Intake, Knowledge
- Trial name
- NCT07366437
- Testing
- Rainbow Veggie Club
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Penn State University
Pregnancy Related, Neurodevelopmental Disorders
Prenatal Iodine Supplementation and Early Childhood Neurodevelopment
A randomized controlled trial to determine the effect of reducing iodine from vitamin and mineral supplements for pregnant women who have adequate iodine intakes (>165 μg/d from food alone) on cognitive development of children at…
- Conditions
- Pregnancy Related, Neurodevelopmental Disorders, Nutrition Disorder, Fetal
- Trial name
- PoppiE (NCT04586348)
- Testing
- Low Iodine Supplement, Standard Iodine Supplement
- Where
- Australia
- Volunteers
- 794 people, healthy volunteers welcome
- Sponsor
- South Australian Health and Medical Research Institute
Skeletal Disorder
Bone and Muscle Health in Kids
Vitamin D deficiency in childhood leads to poor bone growth and muscle weakness, yet it is unknown if the amount of vitamin D a woman consumes during her pregnancy affects her child's bone and muscle development.
- Trial name
- BONUSKids (NCT03537443)
- Testing
- Cholecalciferol (vitamin D3)
- Where
- Bangladesh
- Volunteers
- 642 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Breast Feeding, Exclusive, Breastfeeding
Social Transfers for Exclusive Breastfeeding
The goal of this study is to assess the effectiveness of social transfers on exclusive breastfeeding rates in Lao PDR. The main questions it aims to answer are: 1.
- Conditions
- Breast Feeding, Exclusive, Breastfeeding, Development, Child, Development, Infant
- Trial name
- STEB (NCT05665049)
- Testing
- Social Transfer
- Where
- Laos
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Swiss Tropical & Public Health Institute
Oral Health in Pregnancy and Early Childhood, Early Childhood Caries (ECC)
Midwives' Perspectives on Oral Health in Pregnancy and Early Childhood: A Cross-Sectional Online Survey
This study aims to explore how midwives in Germany perceive their professional role in the context of oral health of pregnant women and young children.
- Conditions
- Oral Health in Pregnancy and Early Childhood, Early Childhood Caries (ECC), Health Promotion by Midwives
- Trial name
- NCT07572799
- Volunteers
- 200 people
- Sponsor
- University Medical Center Goettingen
Depression - Major Depressive Disorder, Childhood Traumas
Resolving Early Life Stress: Psychotherapy Outcomes and Neurobiology in Complex Depression
The RESPOND trial explores the link between early life adversity and later life depressive symptoms. The investigators have designed a new psychological therapy tailored to address the symptoms that can be caused by difficult…
- Trial name
- RESPOND (NCT07250893)
- Testing
- Psychotherapy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Home Injury
Early Childhood, Home Injuries, Mothers ' Knowledge, Mothers' Attitude
Home-Related Injuries among Early Childhood: Rural Mothers' Knowledge, Attitudes and Practice regarding First Aid in Matrouh Governorate, Egypt Keywords: Home injuries, Early childhood, Rural mothers, First aid, Matrouh…
- Trial name
- NCT05984836
- Testing
- Implement health education
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Matrouh University
Childhood Obesity
Preventing Childhood Obesity Through Early Guidance
The goal of this study is to compare the effectiveness of structured CHW- provided home visits, using an intervention created through community-based participatory research, to standard care received through WIC office visits in…
- Trial name
- NCT01905072
- Testing
- Education Home Visits
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- Arizona State University
Child Development
Examining the Role of Pain in the Link Between Early Childhood Adversity and Psychopathology
The goal of this study is to investigate the role of physical pain in the link between childhood adversity and later psychopathology.
- Trial name
- NCT06445712
- Testing
- Parental Support Cold Pressor Task
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Washington University School of Medicine
Families Experiencing Homelessness With Children Under 48 Months of Age
Collaboration to Promote Early Childhood Well Being in Families Experiencing Homelessness
The purpose of this study is to help us learn what are the best services to promote young children's healthy development for families who are experiencing homelessness. Participants may participate in three programs: 1.
- Trial name
- NCT03530137
- Testing
- Healthy Home, Attachment and Biobehavioral Catch-up Infant (6-24 months) and Toddler (24-48 months)., HealthySteps
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Duke University