Clinical trials: Early Intervention, Educational
Visual Impairment, Cerebral Visual Impairment
VIPPSTAR-G1 Digital Early Intervention for Visual Impairment
Visual impairment in infancy is associated with significant risks for neurodevelopmental impairment. Early intervention based on enriched visual and multisensory experiences may promote neuroplasticity and improve developmental…
- Conditions
- Visual Impairment, Cerebral Visual Impairment, Neurodevelopmental Disorders, Prematurity
- Trial name
- VIPPSTAR-G1 (NCT07717671)
- Testing
- VIPPSTAR Digital Early Intervention, Standard Clinical Care
- Where
- 5 sites in Belgium, Italy and 1 more
- Volunteers
- 150 people
- Sponsor
- Università degli Studi di Brescia
Myelodysplastic Syndromes
Early and Low Dose Deferasirox (3.5 mg/kg FCT) to Suppress NTBI and LPI as Early Intervention to Prevent Tissue Iron Overload in Lower Risk MDS
The scientific rationale for this study is the evolving understanding that iron-induced tissue damage is not only a process of progressive bulking of organs through high-volumes iron deposition, but also a reactive iron species…
- Trial name
- NCT03920657
- Testing
- Deferasirox
- Where
- 10 sites in Italy
- Volunteers
- 11 people
- Sponsor
- Fondazione Italiana Sindromi Mielodisplastiche-ETS
Colorectal Cancer, Peritoneal Metastases
ctDNA as a Assisted Diagnosis, Early Intervention and Prognostic Marker for Peritoneal Metastases From Colorectal Cancer
This is a prospective, open-label, randomized controlled clinical trial, by monitoring the serum ctDNA mutational profile using NGS, aiming to elucidate the correlation between the postoperative ctDNA status and the assisted…
- Trial name
- NCT04752930
- Testing
- ctDNA monitoring, Imageology
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Atrial Fibrillation
PULSed Field Ablation for Atrial Fibrillation Using a Balloon for Early Intervention - Study
This study is a prospective, multicenter, randomized, open-label, blinded end-point, controlled clinical trial to investigate the impact of first line pulsed field ablation during 12 months follow-up in patients with early-stage…
- Trial name
- PULSE (NCT07621003)
- Testing
- Ablation of atrial fibrillation (AF)
- Where
- 10 sites in Germany
- Volunteers
- 264 people
- Sponsor
- Asklepios proresearch
Cerebral Palsy, Speech Function
The Relationship of Speech Function and Quality of Life in Children With Cerebral Palsy: A Longitudinal Study
Cerebral palsy (CP) encompass a group of non-progressive, non-contagious motor conditions that cause physical disability in human development.
- Conditions
- Cerebral Palsy, Speech Function, Quality of Life
- Trial name
- NCT01948154
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Substance Use Disorders, Adolescent Behavior
The Canadian Underage Substance Use Prevention Trial
Despite having made some strides with respect to reducing adolescent drinking rates, illicit substance use and substance use disorders (SUDs) remain significantly above national targets for health promotion and disease prevention…
- Conditions
- Substance Use Disorders, Adolescent Behavior, Adolescent Development
- Trial name
- CUSP (NCT04198974)
- Testing
- PreVenture Training (PTtT), PreVenture Training+Implementation Facilitation
- Where
- 4 sites in Canada
- Volunteers
- 12,500 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Alcohol Use
Project Guard: Reducing Alcohol Misuse/Abuse in the National Guard
The overall goal for the study is to test the efficacy of a smartphone app which includes an alcohol brief intervention (SP-BI) versus an Enhanced Usual Care (EUC) condition for National Guard members in the State of Ohio who…
- Trial name
- NCT02860442
- Testing
- Smartphone brief intervention (SP-BI), Enhanced Usual Care (EUC)
- Where
- 2 sites in United States
- Volunteers
- 850 people
- Sponsor
- Keming Gao
Posttraumatic Stress Disorder, Depression
Controlled Trial of Early Intervention With Children and Adolescents Exposed to Nonrelational Traumatic Events
Background: International studies have shown that a substantial number of children and adolescents are exposed to potentially traumatic events.
- Conditions
- Posttraumatic Stress Disorder, Depression, Anxiety
- Trial name
- NCT02299583
- Testing
- Preventive intervention trauma-informed early intervention
- Where
- Denmark
- Volunteers
- 684 people
- Sponsor
- Carolina Magdalene Maier
Obesity
Prevention of Childhood Obesity
This study is conducting preliminary testing to find out whether a particular educational program can alter parental overcontrol of their children's eating.
- Trial name
- NCT00788203
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Stanford University
Dysphagia, Head and Neck Cancer
Feasibility of Early Swallowing and Speech Intervention for Head and Neck Cancer Patients Treated SURGically
Oral cavity cancer (OCC) is one of the most common cancers worldwide, with tongue cancer being one of the most common subtypes. Patients with oral cancers can experience painful swallowing, swallowing difficulty (dysphagia), and…
- Trial name
- ESSI-SURG (NCT06192771)
- Testing
- ESSI-SURG, Standard-of-Care
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Math Learning Disability, Learning Disabilities
Intervention on Mathematical Problem-Solving Skills
The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing and remediating weaknesses in arithmetic skills in children, including those with mathematical learning…
- Conditions
- Math Learning Disability, Learning Disabilities, Learning Disabilities, Child, Dyscalculia
- Trial name
- NCT07778706
- Testing
- Speeded practice training, Arithmetic strategy training
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Stanford University
Eating Disorders
Study of the Effectiveness of a Systematic Minimal Early Intervention on Care Engagement in Adults With Eating Disorders Requesting Specialized Treatment.
Eating disorders (EDs) are complex psychiatric conditions-such as anorexia nervosa and bulimia nervosa-often emerging in young adulthood and associated with high morbidity and mortality.
- Trial name
- AGIS-TCA (NCT07411807)
- Testing
- Program (Systematic Minimal Early Intervention for Eating Disorders)
- Where
- France
- Volunteers
- 215 people
- Sponsor
- Centre Hospitalier St Anne
Autism
Interventions for Communication in Autism Network
The goal of this project is to compare the efficacy of two interventions for improving spoken language and reducing symptoms of autism.
- Trial name
- ICAN (NCT01018407)
- Testing
- Discrete Trial Training, Interpersonal Developmental Approach
- Where
- 3 sites in United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Coronavirus Infection
Early Intervention in COVID-19: Favipiravir Verses Standard Care
Currently we do not know how best to treat patients infected with COVID-19. This study is looking at whether randomising participants to either favipiravir or to usual care, can help patients with suspected or proven COVID-19…
- Trial name
- PIONEER (NCT04373733)
- Testing
- Favipiravir, Standard of care management
- Where
- 6 sites in Brazil, Mexico and 1 more
- Volunteers
- 502 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Executive Function
Brain Games to Improve Executive Function in São Paulo, Brazil
A growing body of research has highlighted the critical importance of children's self-regulation and executive function skills for their school performance as well as for their later life outcomes.
- Trial name
- NCT03491488
- Testing
- Brain Games
- Where
- Brazil
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Infant Development, Temperament
Turkish Version of Infant Movement Motivation Questionnaire
Purpose: It is the examination of the Infant Movement Motivation Questionnaire of the validity and reliability of Turkish. Pretest: Participants were informed about the aims of the study and fill in a consent form.
- Conditions
- Infant Development, Temperament, Early Intervention, Infant Behavior
- Trial name
- NCT04384796
- Where
- Turkey (Türkiye)
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Obesity
Obesity in Children and Adolescents: Associated Risks and Early Intervention
The investigators hypothesize that Metformin decreases weight, normalizes lipid profile and increases insulin sensitivity; the study team hope to get better effect of weight decrease and metabolic processes repair in the…
- Trial name
- OCA (NCT01677923)
- Testing
- Metformin
- Where
- Lithuania
- Volunteers
- 182 people
- Sponsor
- Lithuanian University of Health Sciences
Postpartum Period, Maternal Mental Health
Brief Psycho-educational Intervention to Enhance Maternal Reflective Functioning in the Early Postpartum Among Primiparous: Pilot Study
This randomized pilot trial tests a brief psycho-educational group program designed to enhance maternal reflective functioning (RF)-the capacity to understand one's own and the baby's behavior in terms of thoughts and…
- Conditions
- Postpartum Period, Maternal Mental Health, Parenting / Maternal Behavior, Primiparity (First-Time Mothers)
- Trial name
- NCT07318168
- Testing
- Thinking Emotions - Postpartum RF Group
- Where
- Israel
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Cerebral Palsy
CareToy Early Intervention in Infants at Risk for Cerebral Palsy
Cerebral Palsy (CP), due to pre-perinatal brain lesions, is a main cause of childhood disabilities with high cost for individuals and society.
- Trial name
- NCT03234959
- Testing
- CareToy intervention, Infant Massage
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- IRCCS Fondazione Stella Maris
Bipolar Disorder, Major Depressive Disorder
Early Intervention for Youth at Risk for Bipolar Disorder
Children or teens with mood swings or depression who have a parent with bipolar disorder are at high risk for developing bipolar disorder themselves.
- Trial name
- NCT01483391
- Testing
- Enhanced Care, Family-Focused Treatment
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of California, Los Angeles