Clinical trials: Early Intervention
Metabolic Disease, Mental Health Wellness 1
Healthy Early Life Moments in Singapore
This study aims to assess whether an integrated continuum of care from the preconception period, across maternity until the first 18 months of life, can promote maternal metabolic and mental health, as well as offspring health…
- Conditions
- Metabolic Disease, Mental Health Wellness 1, Lifestyle Risk Reduction, Maternal Obesity
- Trial name
- HELMS (NCT05207059)
- Testing
- HELMS Lifestyle Intervention
- Where
- Singapore
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
ST Elevation (STEMI) Myocardial Infarction
LA Strain in Predicting Early Complication in STEMI After PPCI
The goal of this observational study To evaluate the predictive value of left atrial strain for in-hospital outcomes in patients with ST-segment elevation myocardial infarction undergoing PPCI.
- Trial name
- NCT07263282
- Testing
- 2D echocardiography
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Assiut University
ADHD, Language Disorders
Clinical Evaluation and Intervention of Developmental Behavioral Diseases Based on Multicenter Cohort Study(CEIDBDBMCS)
Diagnosis of Language Disorder and Attention Deficit Hyperactivity Disorder (ADHD) is difficult for several reasons. This study aims to establish a Chinese multi-center cohort for the early diagnosis of language disorder and ADHD…
- Trial name
- CEIDBDBMCS (NCT06025890)
- Testing
- Functional Training., Observe.
- Where
- China
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Chen Li
Pediatric Obesity
Healthy Start to Increase Physical Activity and Improve Healthy Eating in Early Childcare Centres
Childhood obesity is one of the greatest challenges facing public health and recent evidence shows it begins in preschool aged children.
- Trial name
- NCT02375490
- Testing
- Healthy Start
- Where
- 2 sites in Canada
- Volunteers
- 897 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Pediatric Sleep Problems, Sleep Hygiene
Storybook App vs Cognitive Behavioral Therapy for Child Sleep and Attachment
This completed randomized controlled trial compared two caregiver-delivered interventions for sleep in young children: a multimodal mobile health intervention delivered through the Storybook mobile application and a face-to-face…
- Conditions
- Pediatric Sleep Problems, Sleep Hygiene, Parent-Child Attachment
- Trial name
- STORYBOOK-RCT (NCT07668609)
- Testing
- CBT-Based Psychoeducational Intervention, Storybook Mobile Application Intervention
- Where
- Ecuador
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Católica de Cuenca
Unilateral Cerebral Palsy
Multi Sensory Stimulation And Priming (MuSSAP) in Infants at Risk of Unilateral Cerebral Palsy
A pilot randomized clinical trial exploring the effect of a Multi Sensory Stimulation And Priming (MuSSAP) training on improving manual ability in infants at risk of developing unilateral Cerebral Palsy.
- Trial name
- MuSSAP (NCT05533476)
- Testing
- Multi Sensory Stimulation and Priming, Intensive Usual Care (Upper Limb)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sint Maartenskliniek
Ectopic Tooth Eruption, Palatal Expansion Technique
The Effectiveness of Early Intervention to Correct the Position of PDC:s
Approximately 2-3% of children will have problems with one or both of their permanent or 'adult' canine teeth in the upper jaw. These canine teeth sometimes fail to erupt properly, because they are displaced into the roof of the…
- Conditions
- Ectopic Tooth Eruption, Palatal Expansion Technique, Randomized Clinical Trial
- Trial name
- PDC (NCT06267989)
- Testing
- Extraction of the primary canine teeth, Expansion
- Where
- 3 sites in Germany, Sweden and 1 more
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Breast Self-Examination, Breast Cancer
Experimental Study With Pretest/Posttest Groups Which the Intervention Group Have the System Which Sends Reminder Notifications Directing Them to the Website Containing BSE Training Along With the Illustrations Created for the Practice Prepared by the Researcher on the Determined Ideal Day
H0: Among the intervention and control groups of reminder notifications relating to self-examination H01: Average breast cancer fear score and H02: There is no difference in the average score of breast cancer health beliefs.
- Conditions
- Breast Self-Examination, Breast Cancer, Nursing Caries, Cancer
- Trial name
- BreastSelfExam (NCT05995483)
- Testing
- Early Diagnosis on BSE
- Where
- Cyprus
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Nausea, Vomiting
Placebo in Acupuncture
Placebo control in acupuncture research is challenging and difficult. The primary objective of the study is to explore a study design comparing stimulation by real acupuncture needle, sham acupuncture needle and laser.
- Trial name
- NCT01054495
- Testing
- Acupuncture, Laser acupuncture
- Where
- 2 sites in Norway
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Research Centre of Complementary and Alternative Medicine, Norway
Child Development, Executive Functions (EF)
Sharing Tales That Teach: Shared Picturebook Reading for Early Childhood Emotional and Cognitive Development
Sharing Tales That Teach is a randomised study of a shared picturebook reading programme for 4- to 5-year-old children and their primary caregivers.
- Conditions
- Child Development, Executive Functions (EF), Emotion Regulation
- Trial name
- STTT (NCT07666802)
- Testing
- Emotion-Focused Shared Picturebook Reading, Standard Dialogic Picturebook Reading
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Greenwich
Prostate Cancer (Diagnosis)
Early Diagnosis of PROstate CANcer for Black Men
PROCAN-B+ is a mixed-methods, two-arm, multi-centre randomised controlled trial evaluating a co-designed, peer-led intervention to encourage informed help-seeking and engagement with prostate cancer health checks and Prostate…
- Trial name
- PROCAN-B+ (NCT07620717)
- Testing
- The intervention is a two-hour workshop that includes multiple components to encourage Black men to request prostate cancer diagnosis tests., Waitlist
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Sunderland
Diet, Growth
The prEgnanCy and eArly Childhood nutrItion triaL (ECAIL)
The purpose of this study is to conduct a randomized controlled trial among 800 socially disadvantaged pregnant women and their families to test the effectiveness of a multi-component home visitation nutrition program, compared…
- Conditions
- Diet, Growth, Infant, Physical Activity
- Trial name
- ECAIL (NCT03003117)
- Testing
- Experimental: Intervention Program, Active comparator: Usual Care
- Where
- 2 sites in France
- Volunteers
- 607 people, healthy volunteers welcome
- Sponsor
- French Red Cross
Infant Nutrition Disorders, Feeding Patterns
Effectiveness of a Dietary Counseling to Prevent Early Consumption of Added Sugar and Ultra-processed Foods
The purpose of the study is to prevent the early introduction of added sugar and ultra-processed foods and evaluate the impact on breastfeeding duration, complementary feeding quality, growth and prevalence of caries during the…
- Conditions
- Infant Nutrition Disorders, Feeding Patterns, Health Knowledge, Attitudes, Practice
- Trial name
- NCT03841123
- Testing
- Dietary Counseling
- Where
- Brazil
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
Healthy
The Effect of Dairy on Bone Mass and Body Composition in 4th-8th Grade Boys and Girls
Building stronger bones during pubertal growth could reduce lifelong fracture risk. This project is an 18 month dairy intervention study for overweight and healthy weight 4th-8th grade boys and girls.
- Trial name
- B3 (NCT00635583)
- Testing
- Increased Dairy Consumption
- Where
- 2 sites in United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Purdue University
Adolescent Mental Health, Physical Inactivity
Active Families, Healthy Minds: A Family-Centered School Physical Activity Program for Early Adolescents
This study evaluates the effectiveness of a family-centered school physical activity program, titled "Active Families, Healthy Minds," designed to improve mental health among early adolescents (ages 10-14) in China.
- Conditions
- Adolescent Mental Health, Physical Inactivity, Mental Well-being, Sedentary Behavior
- Trial name
- AFHM (NCT07380750)
- Testing
- Family-Supported PA Program, School-Only PA Program, Standard Physical Education
- Where
- China
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Jinan University Guangzhou
Psychosis
Culturally Adapted Psychosocial Interventions for Early Psychosis in a Low-resource Setting
Primary Aims: To determine the clinical efficacy of Culturally adapted Cognitive Behavioral Therapy (CaCBT) and Culturally adapted Family Intervention (CulFI) compared to Treatment As Usual (TAU) on reducing overall symptoms of…
- Trial name
- CaPSI (NCT05814913)
- Testing
- CaCBT for psychosis, Culturally adapted Family Intervention (CulFI) for psychosis
- Where
- Pakistan
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Living and Learning
Colorectal Cancer
Low-Literacy Physician-Patient Intervention Promoting Colorectal Cancer Screening
The purpose of this study is to evaluate the effectiveness of a low literacy, physician and patient-directed intervention to promote colorectal cancer (CRC) screening among the medically underserved.
- Trial name
- NCT01103479
- Testing
- Physician Intervention, Physician and Patient Intervention
- Where
- 2 sites in United States
- Volunteers
- 569 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Math Learning Disability, Learning Disabilities
Intervention on Mathematical Problem-Solving Skills
The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing and remediating weaknesses in arithmetic skills in children, including those with mathematical learning…
- Conditions
- Math Learning Disability, Learning Disabilities, Learning Disabilities, Child, Dyscalculia
- Trial name
- NCT07778706
- Testing
- Speeded practice training, Arithmetic strategy training
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Stanford University
Depressive Symptoms, Generalized Anxiety, or Psychological Stress
Mobile Intervention for Mental Health of Family Caregivers in Thailand
The primary objective of this study is to evaluate the effectiveness of the CAMMA intervention in reducing psychological distress among family caregivers of adults with chronic conditions in Thailand.
- Trial name
- NCT06722287
- Testing
- Caregiver Mental Health Mobile Application (CAMMA) Intervention, Usual Care Group
- Where
- Thailand
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Math Learning Disability, Child Development
Interventions in Mathematics and Cognitive Skills
The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing, and remediating weaknesses in, numerical skills in children, including those with mathematical learning…
- Conditions
- Math Learning Disability, Child Development, Developmental Disability, Learning Disabilities
- Trial name
- NCT05201534
- Testing
- Interventions in Mathematics and Cognitive Skills - Experimental, Interventions in Mathematics and Cognitive Skills - Active Comparator
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Stanford University