Clinical trials: Echocardiography
Ultrasound
Live Stream of Ultrasound in Prehospital Medical Care
Prehospital emergency ultrasound (PEU) is being increasingly used in different preclinical emergency systems across the world. Ultrasound examinations in emergency situations, however, remain challenging even in the hospital…
- Trial name
- NCT04612816
- Testing
- Prehospital ultrasound
- Where
- Austria
- Volunteers
- 25 people
- Sponsor
- Medical University of Vienna
Transesophageal Echocardiography Contrast Agents
Agitated Saline, Albumin, or Propofol-albumin Mixture for Enhanced Contrast in TEE Examinations
This is a prospective, randomized, controlled study to determine if albumin and propofol or albumin only will provide superior qualitative contrast enhancement during TEE bubble studies compared to agitated saline.
- Trial name
- NCT02613052
- Testing
- normal saline, human albumin, human albumin and propofol
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of California, San Diego
Ischemic Heart Disease
DSE vs. FFR in SCAD and BYSTANDER Lesions
Enrollment: Patients with stable coronary artery disease (SCAD) and moderate coronary artery stenoses (30-70 %) Patients with acute myocardial infarction and moderate stenosis of non-culprit arteries (NCL; BYSTANDER LESION) Aims…
- Trial name
- DSE-vs-FFR (NCT03383718)
- Testing
- Revascularisation, Optimal Medical Treatment/OMT
- Volunteers
- 200 people
- Sponsor
- Bajcsy-Zsilinszky Hospital
Acute Coronary Syndrome
Screening for Abdominal Aortic Aneurysm Using a Portable Transthoracic Echocardiography Among Patients With Acute Coronary Syndrome
The prevalence of Abdominal Aortic Aneurysm among 65 years old individuals worldwide is 1-2%. when diagnosis is confirmed by abdominal Ultrasound the prevalence is 5.5% in men and 1% in women.
- Trial name
- NCT01863524
- Where
- 2 sites in Israel
- Volunteers
- 90 people
- Sponsor
- HaEmek Medical Center, Israel
Multi-modality Echocardiography, Primary Electrical Disease
Multi-modality Echocardiography for Cardiac Assessment in Primary Electrical Disease
From 2020 to 2023, patients with primary electrical disease (idiopathic ventricular fibrillation, long QT syndrome, Andersen-Tawil syndrome type I, Brugada syndrome, early repolarization syndrome, CPVT, and short QT syndrome)…
- Trial name
- NCT06172842
- Testing
- Echocardiography
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Heart Failure，Congestive
Serum Catestatin Expression and Cardiometabolic Parameters in Patients With Congestive Heart Failure
The congestive heart failure (HF) is a condition associated with substantial morbidity, mortality, and high healthcare expenditures.
- Trial name
- CATSTAT-HF (NCT03389386)
- Testing
- Blood withdrawal for laboratory analysis, Standard-of-care treatment, Transthoracic echocardiography (TTE)
- Where
- Croatia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Josko Bozic
Pulmonary Embolism
Tenecteplase Pulmonary Embolism Italian Study
To assess the efficacy and safety of Tenecteplase versus Placebo in normotensive patients with sub-massive Pulmonary Embolism and Right Ventricular Dysfunction (RVD) all receiving unfractionated heparin (UFH)
- Trial name
- NCT00222651
- Testing
- tenecteplase
- Where
- 30 sites in Italy
- Volunteers
- 180 people
- Sponsor
- University Of Perugia
Bicuspid Aortic Valve
A Multicentre Retrospective Study on Bicuspid Aortic Valve
Bicuspid Aortic Valve (BAV) is a common congenital heart disease with an incidence ranging from 0.16% in Asians to 2% in Westerners.
- Trial name
- NCT05818722
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Shock
Effects of Hemodynamic Monitoring Using the ImaCor Single Use Transesophageal Echocardiography Probe in Critically Ill Patients
Hemodynamic management of critically ill patients is a constant challenge in the intensive care unit (ICU). Commonly used monitoring parameters to guide hemodynamic management generally consist of measurements of pressures…
- Trial name
- ImaCor II (NCT02048566)
- Testing
- ImaCor PM, ImaCor SM, Control PM
- Where
- Switzerland
- Volunteers
- 550 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Heart Failure, Systolic, Ketonemia
Ketones in Heart Failure - Effects on Cardiac Efficiency
Ketones may have beneficial effects on myocardial metabolism and hemodynamics. In the present study, healthy test subjects and patients with heart failure with reduced ejections fraction will be investigated in a randomized…
- Trial name
- NCT03073356
- Testing
- Infusion of 3-OHB
- Where
- Denmark
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Acute Coronary Syndrome
Differential Effect of Ticagrelor Versus Prasugrel on the Adenosine-induced Coronary Vasodilatory Responses in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention
This is a prospective, randomized, single-blind, investigator-initiated, crossover study. Patients with Acute Coronary Syndrome (ACS) subjected to percutaneous coronary intervention (PCI), are randomized after informed consent…
- Trial name
- NCT01642966
- Testing
- Prasugrel, Ticagrelor
- Where
- Greece
- Volunteers
- 56 people
- Sponsor
- University of Patras
Speckle Tracking, Fetus Fetus
Speckle Tracking Echocardiography in Infants, Prenatally and Postnatally
Comparison of prenatal and postnatal cardiac function assessed by echocardiography using pulsed wave Doppler, Tissue Doppler and speckle tracking (strain and strain rate) between foetuses/neonates with a structural heart disease…
- Conditions
- Speckle Tracking, Fetus Fetus, Neonate, Structural Heart Disease
- Trial name
- STIPP (NCT05601375)
- Testing
- Echocardiography
- Where
- Netherlands
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Critical Illness, Elevated Left Atrial Pressure
The Use of Single-Beat TE-e' in Evaluation of Left Atrial Pressure in Critically Ill Patients: The TELAP-ICU Trial
This study evaluates a new single-beat echocardiographic technique (TE-e', the time difference between the onset of the mitral inflow E wave and the septal e' wave on tissue Doppler imaging) for estimating left atrial pressure…
- Conditions
- Critical Illness, Elevated Left Atrial Pressure, Left Ventricular Diastolic Dysfunction, Echocardiography
- Trial name
- TELAP-ICU (NCT07820319)
- Testing
- Echocardiography
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Queen Mary Hospital, Hong Kong
Atrial Fibrillation, Stroke
Transesophageal Echocardiography to Identify pAtients With Low Risk of Stroke in Atrial Fibrillation - TIARA Pilot Study
In this multi centre pilot study we will perform TEE in patients with AF who are eligible for VKA treatment. TTE will be used as pre-screening: if TTE shows left atrial abnormalities or aortic plaque, patients will be excluded…
- Trial name
- TIARA (NCT00224757)
- Testing
- Transoesophageal echocardiography
- Where
- 10 sites in Netherlands
- Volunteers
- 227 people
- Sponsor
- The Interuniversity Cardiology Institute of the Netherlands
Hypertension, Left Ventricular Hypertrophy
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)
Studying the causal roles of components of the renin-angiotensin-aldosterone system (including angiotensin-(1-7) (Ang-(1-7)), angiotensin-converting enzyme 2 (ACE2), Ang II, and ACE), uric acid, and klotho in pediatric…
- Conditions
- Hypertension, Left Ventricular Hypertrophy, Left Ventricular Dysfunction, Left Atrial Dilatation
- Trial name
- PHRASE (NCT04752293)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Patent Ductus Arteriosus
Echocardiographically Guided Versus Standard Ibuprofen Treatment for Patent Ductus Arteriosus
Patent ductus arteriosus (PDA) is a very common condition in immature newborn babies and it has been associated to morbidity and mortality.
- Trial name
- NCT01593163
- Testing
- Ibuprofen EchoG, Standard ibuprofen treatment
- Where
- Spain
- Volunteers
- 49 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario la Paz
Ventricular Dysfunction, Cardiotoxicity
Optimising Screening for the Cardiotoxic Effects of Cancer Therapy
Cancer is a major worldwide health problem, with around 330.000 new annual cases only in the UK. Improved survival rates due to better treatments have lead to an increase in the prevalence of chemotherapy related cardiac disease…
- Conditions
- Ventricular Dysfunction, Cardiotoxicity, Chemotherapeutic Toxicity
- Trial name
- NCT06817044
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Barts & The London NHS Trust
Trauma Chest
Transesophageal Echocardiography To Diagnose Blunt Traumatic Aortic Injury Traumatic Aortic Injury
To determine test performance of transesophageal echocardiography performed by emergency physician ultrasound for the identification of blunt traumatic aortic injury in chest trauma.
- Trial name
- NCT05226858
- Testing
- Transesophageal echocardiography (TEE)
- Where
- 6 sites in Malaysia
- Volunteers
- 56 people
- Sponsor
- Hospital Raja Permaisuri Bainun
Patent Foramen Ovale, Cryptogenic Stroke
Comparison of Lower vs Upper Extremity Injection Agitated Saline to Identify Patent Foramen Ovale With Echocardiography
Study Title LOwer vs upper extremity injection agitated saline for identifiCation of pATent foramen ovalE (LOCATE) Pilot study to determine safety of lower extremity injection of agitated saline for echocardiography of the heart.
- Conditions
- Patent Foramen Ovale, Cryptogenic Stroke, Embolic Infarction
- Trial name
- LOCATE (NCT07009678)
- Testing
- intravenous access in greater saphenous vein compared to upper extremity site.
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- St. John's Hospital
Pregnancy Related
The Right Heart During and After Pregnancy - an Echocardiographic Study
The main goal is to establish echocardiographic reference values of the right heart for pregnant women, assuming they differ significantly from those of non pregnant women of same age.
- Trial name
- EVA (NCT03402971)
- Testing
- echocardiography
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Gero Bunniger