Clinical trials: Edema
Impacted Third Molar Tooth
Assessment of the Relationship Between Edema Measurement Methods After Impacted Mandibular Third Molar Surgery.
The aim of this study is to evaluate the correlation between two point distance measurements performed by surgeon on patients face with foldable ruler, which is the most commonly used method, and the subjective scoring will be…
- Trial name
- NCT03747237
- Testing
- Edema measurement methods
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Macular Edema, Uveitis
PeriOcular and INTravitreal Corticosteroids for Uveitic Macular Edema Trial
To evaluate the relative efficacy of three commonly utilized regional corticosteroids for the regional treatment of uveitic macular edema: periocular triamcinolone acetonide; intravitreal triamcinolone acetonide; intravitreal…
- Trial name
- POINT (NCT02374060)
- Testing
- Periocular triamcinolone 40 mg, Intravitreal triamcinolone 4 mg, Dexamethasone intravitreal implant
- Where
- 26 sites in United States, Australia and 2 more
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- JHSPH Center for Clinical Trials
Edema Face
Tacrolimus for Malar Edema
Elective lower eyelid surgery is a common cosmetic procedure. Facial swelling is a common complication. Studies suggest that this facial swelling is part of a complex inflammatory process.
- Trial name
- NCT03715387
- Testing
- Tacrolimus Topical 0.1% Topical Ointment, Polysporin Ointment
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pain, Postoperative, Edema
Effectiveness of Light-emitting Diode (LED) Photobiomodulation in the Extraction of Retained Lower Third Molars
In dentistry, one of the most common surgical procedures is the removal of included third molars. This surgery generates great morbidity to patients for causing pain, edema and trismus due to surgical trauma.
- Conditions
- Pain, Postoperative, Edema, Trismus, Quality of Life
- Trial name
- NCT03442166
- Testing
- LED group
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Pain
Evaluation of the Effectiveness of the Use of the Therapeutic Bandage Method in Third Molar Surgery
Extraction of lower third molars semi-included or included is one of the most performed procedures in oral surgery, and inherent to the procedure there is a postoperative inflammatory response.
- Trial name
- NCT03393533
- Testing
- Group I, Group II
- Where
- Brazil
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Macular Edema, Epiretinal Membrane
Intravitreal Dexamethasone Implant for Persistent Macular Thickening and Edema After Vitrectomy for Epiretinal Membrane
This study seeks to evaluate the effect of the intravitreal 0.7mg dexamethasone implant on central macular thickness and visual acuity in those patients with persistent macular edema after pars plana vitrectomy for epiretinal…
- Conditions
- Macular Edema, Epiretinal Membrane, Vitrectomy
- Trial name
- DEMO (NCT02995746)
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Oedema, Pulmonary
A First Time in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Healthy Subjects and Stable Heart Failure Patients
This study is the first administration of GSK2798745 in humans. This will be a sponsor un-blinded, placebo-controlled study to investigate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of GSK2798745…
- Trial name
- NCT02119260
- Testing
- GSK2798745 solution, GSK2798745 suspension, GSK2798745 capsule
- Where
- 2 sites in United Kingdom
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
CYSTOID MACULAR EDEMA
Acute Pseudophakic Cystoid Macular Edema Treatment Trial: Intravitreal Ranibizumab Versus Triamcinolone Acetonide
This is an open-label, Phase I/II study evaluating intravitreal ranibizumab (R) vs. intravitreal Triesence (triamcinolone acetonide) (T) in subjects with acute pseudophakic cystoid macular edema (CME).
- Trial name
- NCT02294656
- Testing
- Ranibizumab,, Triamcinolone acetonide
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Soll Eye
Bone Marrow Edema
Study for the Treatment of the Bone Marrow Edema:Core Decompression VS Bone Marrow Concentrate (BMC) VS Bone Substitute
Randomized, controlled, three-arm, double-blind study : control group, treated with core decompression technique VS subchondral plasty by injecting i-FactorTM VS injections of autologous BMC.
- Trial name
- BME-TARGET (NCT03112122)
- Testing
- autologous bone marrow concentrate, bone substitute i-FactorTM, core decompression
- Where
- Italy
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Edema Leg
The Effect of Compression Stockings on Edema and Discomfort During Short Haul Flights
Compression stockings have beneficial effects on the development of venous thromboembolic complications and oedema during long- haul flights.
- Trial name
- NCT03546725
- Testing
- Compression stocking
- Where
- Denmark
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Cystoid Macular Edema After Phacoemulsification
Prophylactic Effect of Ketorolac Tromethamine on the Cystoid Macular Edema After Phacoemulsification in Diabetic Patients
The aim of the study is determining the prophylactic effect of ketorolac tromethamine drop 0.5% eye drop on the functional and anatomical ocular characteristics of the diabetic patients after the phacoemulsification surgery.
- Trial name
- NCT03551808
- Testing
- using of Ketorolac Tromethamine Eye Drop
- Where
- Iran
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Tooth Extraction, Molar, Third
Acupuncture on Anxiety and Inflammatory Events Following Surgery of Mandibular Third Molars
The aim of this study was to compare the effect of acupuncture and placebo acupuncture for the control of pain, edema, and trismus following the extraction of third molars and control of preoperative anxiety.
- Conditions
- Tooth Extraction, Molar, Third, Pain, Postoperative, Trismus
- Trial name
- NCT03545022
- Testing
- Acupuncture
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Retinal Vein Occlusion With Macular Edema
Comparison of Therapeutic Effects Between Intravitreal Injection of Bevacizumab With Intravitreal Injection of Bevacizumab and Targeted Laser Photocoagulation of Non Perfused Areas of Retina in Patients With Acute Retinal Vein Occlusion
Patients with new onset retinal vein occlusion in less than 3 month whom has visual acuity less than 20/40 and central macular thickness more than 250micrometer and non perfused areas of retina more than 10 DD are included in…
- Trial name
- bevacizumab (NCT03353324)
- Testing
- intravitreal injection of bevacizumab, intravitreal injection of bevacizumab+ targeted laser
- Where
- Iran
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Macular Edema Following Cataract Surgery
Trientine Hydrochloride for the Prevention of Macular Edema After Cataract Surgery in Patients With Type 2 Diabetes Mellitus
The primary purpose of the protocol is to evaluate whether Trientine Hydrochloride, a copper chelator which is an agent that binds with and removes copper, will be effective in minimizing macular edema after cataract surgery in…
- Trial name
- NCT01295073
- Testing
- Trientine Hydrochloride, For Arm B there is no therapeutic intervention other than standard of care, which is cataract surgery.
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
Impacted Third Molar Tooth
Topical Hydrocortisone for Pain and Edema Control After Third Molar Surgery
The investigators set out to develop a clinical trial in order to test the topical use of hydrocortisone as a intraoperative irrigant solution.
- Trial name
- NCT03179813
- Testing
- Hydrocortisone, Control
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Edematous, Synovitis
Double-Blinded Clinical Trial Using Apatone®B for Symptomatic Postoperative Total Joint Replacements
This research study is being conducted to determine if taking oral (by mouth in pill form) Apatone®B (a combination of Vitamins C and K3) will reduce chronic joint discomfort and improve function of non-infected symptomatic…
- Conditions
- Edematous, Synovitis, Foreign Body Reaction, Osteolysis
- Trial name
- Apatone-B (NCT01272830)
- Testing
- Apatone®B
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- IC-MedTech Corporation
Edema
Bioequivalency Study of Torsemide Tablets Under Fasting Conditions
The objective of this study was the bioequivalence of a Roxane Laboratories' Torsemide Tablets, 20 mg, to Demadex® Tablets, 20 mg (Roche) under fasting conditions using a single-dose, 2-treatment, 2-period, crossover design.
- Trial name
- NCT00602303
- Testing
- Torsemide
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Edema
Bioequivalency Study of Torsemide Tablets Under Fed Conditions
The objective of this study was the bioequivalence of a Roxane Laboratories' Torsemide Tablets, 20 mg, to Demadex® Tablets, 20 mg (Roche) under fed conditions using a single-dose, 2-treatment, 2-period, crossover design.
- Trial name
- NCT00602615
- Testing
- Torsemide
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Tendinopathy
Mechanisms Behind Development of Tendinopathy
There has been an increasing amount of musculoskeletal injuries the past decades and overused tendons represents a major problem both for leisure and occupational activities.
- Trial name
- TESINaC (NCT02797925)
- Testing
- Training
- Where
- Denmark
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Epiretinal Membrane, Pseudophakic Cystoid Macular Edema
"Cataract Surgery in Eyes With Epiretinal Membrane"
The purpose of the study is to evaluate retinal thickness change and the occurrence of central structural retinal changes after uneventful small-incision cataract surgery in eyes with asymptomatic early stages of epiretinal…
- Conditions
- Epiretinal Membrane, Pseudophakic Cystoid Macular Edema, Irvine-Gass Syndrome, Cataract
- Trial name
- NCT03404323
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- St John of God Hospital, Vienna