Clinical trials: Effect Increased
Healthy
Effect of Fruit and Vegetable Intake on Markers of Fruit and Vegetable Consumption
This study will examine what contribution of 'markers' of fruit and vegetable (FV) intake in blood and urine is most closely related to FV intake.
- Trial name
- BIOFAV (NCT01591057)
- Testing
- 2 portions of fruit and vegetables per day, 5 portions of fruit and vegetables per day, 8 portions of fruit and vegetables per day
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Poor Semen Quality
Effects of Plant Extracts on Semen Quality
this is a prospective randomized placebo-controlled double-blinded trial investigating the effect of plant extracts from Alpinia galanga and Punica granatum on human semen quality.
- Trial name
- NCT01357044
- Testing
- Extracts of Punica granatum and Alpinia galanga
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Horsens Hospital
Healthy Adult Participants
Geko® T3 One vs Two Study
The primary objective of this study to assess the haemodynamic effects of unilateral and bilateral geko® T3 stimulation on lower-limb circulation, measured by femoral artery and vein blood flow.
- Trial name
- NCT07849257
- Testing
- NMES
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Kieron.Day
Chronic Pain, Arthritis Hand
Effects of the Nottingham Augmented Reality (AR) App for Arthritis Hand Joint Pain
The aim of this run-in design, feasibility study is to assess outcomes (including opioid-use, pain intensity, emotional function, and general physical function) for an augmented reality illusion therapy in participants with…
- Conditions
- Chronic Pain, Arthritis Hand, Opioid Use
- Trial name
- NCT05634291
- Testing
- Standard of care, Nottingham AR smartphone app with active intervention
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- VRx Medical Inc
Healthy
Effect of Food and Increased Gastric pH Value on Bioavailability of a Single Dose of BI 207127 in Healthy Caucasian and Japanese Subjects
The purpose of this trial is to investigate the effect of food with different fat content and of gastric pH increase (mediated by multiple dosing of omeprazole) on the relative bioavailability of deleobuvir.
- Trial name
- NCT01983566
- Testing
- BI 207127 high fat, BI 207127 with Omeprazole, BI 207127
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Sedentary Lifestyle, Blood Pressure
Blueberry Enhances Activity and Cognition Through Increased Vascular Efficiency
Recent evidence suggests that increased berry intake results in a variety of health benefits, across multiple health domains. This 3-month randomized, double-blind, placebo-controlled trial assess the effects of combining daily…
- Conditions
- Sedentary Lifestyle, Blood Pressure, Arterial Stiffness, Overweight and Obesity
- Trial name
- BEACTIVE (NCT04049162)
- Testing
- Blueberry Plus Exercise (BB-EX)
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Duke University
Healthy
Green Tea and Ultraviolet Light-induced Skin Damage
The purpose of this study is to investigate whether topically applied constituents of green tea [caffeine or (-)-epigallocatechin gallate; EGCG] have a protective effect on skin exposed to ultraviolet light (UV).
- Trial name
- NCT00134381
- Testing
- Green Tea
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Healthy Subjects
Effects of Increased Muscle Mass on Resting Metabolic Rate
Healthy males are randomized to isometric exercise for three months with either extra protein or extra calories in the form of a fast food meal/day in order to study if increase in muscle mass increases resting metabolic rate and…
- Trial name
- NCT01325038
- Testing
- Isometric exercise
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Pain, Postoperative
Does IVPCA Increase Opioid Consumption and Side Effects in Fast Track Orthopedic Procedures?
The study aims to compare the use of intravenous patient controlled analgesia (IVPCA) versus the delivery of pain relief (per oral and intravenous (IV) medications as rescues analgesia) on an as needed basis within a well defined…
- Trial name
- NCT02880800
- Testing
- Morphine as IVPCA, Hydromorphone as IVPCA, Morphine
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Anxiety, Pain
Effect of Augmented Reality on Dental Anxiety and Pain Perception in Children
The aim of this study is to reduce dental anxiety in children by using augmented reality (AG) with a special content and innovative interactive methods, to determine the level of stress experienced by patients during dental…
- Trial name
- NCT06530654
- Testing
- Distraction by dentist, Distraction by cartoon movie, AG-active distraction group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Nonalcoholic Fatty Liver Disease, Type 2 Diabetes
Weight Gain After Smoking Cessation and NAFLD
Nonalcoholic fatty liver disease (NAFLD) is rapidly becoming the most common chronic liver disease. Considering that there are no approved pharmacological treatments, lifestyle modification is necessary and challenging to reduce…
- Trial name
- NCT05550688
- Where
- China
- Volunteers
- 12,941 people, healthy volunteers welcome
- Sponsor
- Ningbo No. 1 Hospital
Healthy Women, Osteocalcin
Jarlsberg Cheese Compared to Camembert Cheese
The study objective consists of the following three aims: 1. To compare the effect of daily intake of Jarlsberg cheese and Camembert cheese in change of the Osteocalcin level in healthy women after 6 weeks. 2.
- Trial name
- NCT04189796
- Testing
- Cheese
- Where
- Norway
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Prof Stig Larsen
Cognitive Impairment, Aging
Influence of Overground Walking on Biomarkers, Cognitive Function, and Quality of Life in Elderly With Mild Cognitive Impairment
The purpose of this research is to investigate the impact of overground walking as a part of a rehabilitation program on the increase in Brain-derived neurotrophic factor (BDNF) levels, decrease in IL-6 levels, decrease in hs-CRP…
- Trial name
- NCT06029920
- Testing
- Overground Walking
- Where
- Indonesia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Atrial Fibrillation (AF)
Effects of a Health Belief Model-Based Community Educational Program to Increase the Awareness of Atrial Fibrillation Among Older Adults: a Randomized Controlled Trial
The goal of this study is to evaluate the effects of a theory-based community educational program among older adults in the community on atrial fibrillation (AF) knowledge.
- Trial name
- NCT06582823
- Testing
- Health belief model-based community educational program, Control
- Where
- Hong Kong
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Water Consumption, Drinking Behavior
Effects of a School-based Intervention to Increase the Water Consumption in Elementary School Children
The purpose of this controlled intervention study is to evaluate the effectiveness of a school-based intervention aiming at increasing the water consumption in elementary school children.
- Trial name
- H2NOE (NCT03852173)
- Testing
- Wasserschulen
- Where
- Austria
- Volunteers
- 1,485 people, healthy volunteers welcome
- Sponsor
- Danube University Krems
Aging, Exercise
The Effect of Exercise on Myokine Production in Aging Persons
The incidence of age-related diseases, such as cancer and cardiovascular diseases, rapidly rises. These days, age-related diseases cause the majority of all healthcare expenses.
- Trial name
- EXI-AGE (NCT05571709)
- Testing
- Exercise training, Questionnaire, Percutaneous muscle biopsy
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Systemic Lupus Erythematosus, Arthritic Psoriasis
A Study to Evaluate BMS-986165 Tablet Formulation Relative to BMS-986165 Capsule Formulation and the Effect of a High-Fat/ High-Calorie Meal and Increased Gastric pH on the BMS-986165 Tablet Formulation
The purpose of this study is to evaluate BMS-986165 tablet formulation versus BMS-986165 capsule formulation. This study will also evaluate the effect of a high-fat/ high-calorie meal and increased gastric pH on the BMS-986165…
- Conditions
- Systemic Lupus Erythematosus, Arthritic Psoriasis, Psoriasis, Inflammatory Bowel Diseases
- Trial name
- NCT03254784
- Testing
- BMS-986165 Capsule, BMS-986165 Tablet
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Children
Effects of Propofol and Ketofol on Core Body Temperature in MRI
Investigators researched the effect of two different types of drugs on core body temperature during magnetic resonance imaging. The hypothesis is in ketamine group, thermo disregulation is not as distinct as in propofol group…
- Trial name
- NCT02931786
- Testing
- propofol, Ketamine propofol mixture
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Lipids
Effects of a Large Increase in Dietary Fats and Cholesterol on HDL Composition and Function in Healthy Subjects
In this study the investigators aimed at measuring the effect of a two-week high-fat/high-cholesterol (HFHC) normocaloric diet on HDL particles biochemical composition and HDL function compared to a two-week…
- Trial name
- NCT02549144
- Testing
- Low fat/cholesterol diet, High fat/cholesterol diet
- Where
- Italy
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Healthy
A Study to Investigate the Effect of Increased Gastric pH on the Oral Bioavailability of the Orexin-2 Receptor Antagonist JNJ-42847922 in Healthy Participants
The purpose of this study is to assess the effects of daily administration of rabeprazole on the single-dose pharmacokinetics of JNJ-42847922 in healthy participants.
- Trial name
- NCT02475161
- Testing
- JNJ-42847922, Rabeprazole
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC