Clinical trials: Effect Increased
Sunburn
A Randomized Controlled Trial to Test the Effects Oxytocin and Vibration Have on Heat Pain Threshold After UV-B Burn
This study aims to answer the question: Does oxytocin increase the pain threshold on thermal heat pain in the presence of vibration on an area of skin exposed to a mild sunburn?
- Trial name
- NCT06651476
- Testing
- oxytocin
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Cognitive Impairment, Aging
Influence of Overground Walking on Biomarkers, Cognitive Function, and Quality of Life in Elderly With Mild Cognitive Impairment
The purpose of this research is to investigate the impact of overground walking as a part of a rehabilitation program on the increase in Brain-derived neurotrophic factor (BDNF) levels, decrease in IL-6 levels, decrease in hs-CRP…
- Trial name
- NCT06029920
- Testing
- Overground Walking
- Where
- Indonesia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Soy Isoflavone Effect, Bone Density, Low
Effects of Soy Isoflavone on Bone Health Among Saudi Female Students Imam Abdulrahman Bin Faisal University.
Low bone mineral density (BMD) has recently increased among young women. Soy Isoflavone as a food supplement, has been found to have potent effect on bone health in postmenopausal women.
- Conditions
- Soy Isoflavone Effect, Bone Density, Low, Bone Density Increased
- Trial name
- NCT04547010
- Testing
- Soy Isoflavone supplement
- Where
- Saudi Arabia
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Intracranial Pressure Increase
Effect of Tourniquet Application on Optic Nerve Sheath Diameter
The aim of the study to investigate the effect of tourniquet application on optic nerve sheath diameter (ONSD) and cerebral oxygenation during lower extremity surgery.
- Trial name
- NCT04758091
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Cryotherapy Effect
Cooling Induces Motor Facilitation With Sympathetic Activation
Cryotherapy has beneficial effects such as motor facilitation, increase isometric force generation, and reduce spasticity. It is known that the muscle spindle has sympathetic innervation.
- Trial name
- NCT05832970
- Testing
- Brief skin cooling
- Where
- Turkey (Türkiye)
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Cardiovascular Diseases, Type 2 Diabetes Mellitus
A Series of Pilot Studies to Evaluate the haemoDynamic and mEtabolic Effects oF apelIn aNd rElaxin
Type two diabetes mellitus (T2DM) is a common, long term metabolic disorder characterised by hyperglycaemia (high blood glucose) resulting from insulin resistance and relative insulin insufficiency.
- Trial name
- DEFINE (NCT03449251)
- Testing
- Apelin, Relaxin, Normal saline
- Where
- United Kingdom
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Risk Reduction, Breast Cancer
Phase IIB Trial of Bazedoxifene Plus Conjugated Estrogens
Women at risk for development of breast cancer and experiencing vasomotor menopausal symptoms (hot flashes) will be randomized to bazedoxifene (BZA) plus conjugated estrogens (CE) for 6 months versus a wait list control.
- Trial name
- NCT04821141
- Testing
- Bazedoxifene and Conjugated Estrogens
- Where
- 6 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Osteoporosis
Brief Osteoporosis Education to Increase Awareness in Middle Aged and Elderly.
Osteoporosis is a growing global concern, particularly as the population of middle-aged and elderly individuals continues to rise within communities.
- Trial name
- BOEIAMAE (NCT05936177)
- Testing
- Patient education
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Selkin Yılmaz Muluk
Dehydration, Cognitive Change
The Effects of Hydration on Gut Health and Thinking
The central hypothesis is that improving hydration through increased water consumption will change the relative abundance of mucolytic bacteria found in the stool.
- Conditions
- Dehydration, Cognitive Change, Gastrointestinal Microbiota
- Trial name
- WatUP (NCT05315531)
- Testing
- Water Intake
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Hamstring Contractures, Muscle Tightness
Immediate and 24-hour Effects of HyperVolt, Body Tempering, and Cupping Compared to Stretching on Hamstring Flexibility
The purpose of this study is to compare the effects of the HyperVolt percussive massage device, body tempering, and dry cupping to static stretching of the hamstrings of healthy adults aged 18-39 years on the active knee…
- Trial name
- NCT05793242
- Testing
- Hypervolt, Body Tempering, Dry cupping
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Schizophrenia
Pharmacologically-augmented Cognitive Therapies (PACTs) for Schizophrenia.
This application seeks renewed support for MH59803, "Dopaminergic substrates of startle gating across species," to extend a clear path of "bench-to-bedside" progress towards a critical paradigm shift in therapeutic models for…
- Trial name
- NCT02634684
- Testing
- Dextroamphetamine
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Childhood Obesity
Brief Physical Activity Program to Increase Physical Fitness in Elementary School Children
The investigators hypothesized that the addition of 6 minutes of exercise during the school day would increase physical fitness in elementary school students as demonstrated by longer distances run in 2 minutes and a decrease in…
- Trial name
- NCT02087774
- Testing
- 6 minutes activity
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Marshall University
Sports Performance
The Effects of Increased vs. Traditional Squat Stance Width on Performance Indices in Elite Rugby League Players
The back squat is a commonly utilized resistance training exercise for the promotion of both performance and musculoskeletal health.
- Trial name
- NCT05505786
- Testing
- Normal stance width, Wide stance width
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Central Lancashire
Growth Disorders, Dietary Exposure
Evaluating the Effects of an Oral Protein Supplement on Children's Growth Patterns
This single-center, randomized controlled pilot study aims to evaluate the efficacy of TruHeight Growth Protein Shake on improving growth patterns in children aged 4-17 years.
- Conditions
- Growth Disorders, Dietary Exposure, Child Development, Bone Development Abnormal
- Trial name
- NCT06329388
- Testing
- TruHeight Growth Protein Shake
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- TruHeight Vitamins
Healthy, Coronary Artery Bypass Graft
Cardioprotective Effects of Increased Endogenous Erythropoietin After Normobaric Oxygen Breathing
Tissue hypoxia is the only accepted trigger for erythropoietin (EPO) production. However, in healthy subjects EPO concentrations have also increased after oxygen breathing. The aim of our study is to confirm these observations.
- Trial name
- NCT00824759
- Testing
- pure oxygen breathing versus air
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Focus of Study is Healthy Women at Risk for Breast Cancer
Pilot Study of Effects of Duavee® on Imaging and Blood Biomarkers In Women With Menopausal Symptoms
Pilot study to test feasibility of 6 months of Duavee® vs wait-list control in post-menopausal women symptomatic for hot flashes.
- Trial name
- NCT04379024
- Testing
- DUAVEE 0.45Mg-20Mg Tablet
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Carol Fabian, MD
Bone Density Increased, Body Height
Milk Supplementation and Bone Health in Children
Objectives: to examine the effects of a Yili child formula milk and regular milk on bone health and growth in young children. Study design: cluster randomized controlled trial.
- Trial name
- NCT05074836
- Testing
- Formula milk, Regular milk, Control foods
- Where
- China
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Virtual Reality, Augmented Reality
VR/AR Educational Module on Oral Care Practices for Home Care Worker
This study is to evaluate the effect of the elderly oral care knowledge, attitude ,self-efficacy ,oral care behavior between the home care workers(HCW) in VR(Virtual reality)/AR(Augmented reality)group and control group after…
- Conditions
- Virtual Reality, Augmented Reality, Oral Care Performance
- Trial name
- NCT05436132
- Testing
- VR and AR oral healthcare curriculum training, traditional teaching methods oral healthcare curriculum
- Where
- Taiwan
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Hereditary Angioedema
Safety and Pharmacokinetics of GNR-038 in Healthy Volunteers
It is an open-label dose-escalating study in sequential cohorts to assess safety and pharmacokinetics of GNR-038.
- Trial name
- NCT04557319
- Testing
- GNR-038, 25 МЕ/kg, GNR-038, 50 МЕ/kg, GNR-038, 100 МЕ/kg
- Where
- Russia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- AO GENERIUM
Physical Activity
Mobile Supportive Teams for Reinforcing Increased Daily Exercise Study
The goal of this research is to examine the addition of a digitally delivered social support training approach to an existing digital program designed to promote a physically active lifestyle among self-selected teams of adults…
- Trial name
- STRIDES (NCT06662292)
- Testing
- Mobile STRIDES app (psychoeducation features), Mobile STRIDES app (self-regulation features), Mobile STRIDES app (social support training features)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of South Carolina