Clinical trials: Effect Neonatal
Effect Neonatal
Using Dexmedetomidine Prior to Intubation in Neonates
Neonatal intubations are performed routinely in a NICU. Most intubations are still performed without the administration of medications (awake intubations).
- Trial name
- NCT05304598
- Testing
- Dexmedetomidine, Usual Care
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maimonides Medical Center
Cleft Lip and Palate
Effect of Novel Nasoalveolar Molding Techniques on Parents' Satisfaction and Short Term Treatment Outcomes in Unilateral Cleft Lip and Palate Infants: A Randomized Controlled Trial
The aim of this trial is to figure out the efficiency of modified Grayson NAM on parents' satisfaction, nasal esthetics, interlabial gap and maxillary arch changes.
- Trial name
- NCT02845193
- Testing
- Modified Nasoalveolar molding, Taping, CAD/NAM
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cairo University
Researcher-Subject Relations
Growth and Development of Children With Congenital Heart Disease (CHD)
The Effect of Individualized Nutrition Training Given to the Families of Children with Congenital Heart Disease (CHD) in the Post-Operative Period on their Growth and Development This study was conducted experimentally to…
- Trial name
- CHD (NCT04903964)
- Testing
- family-centered nutrition education
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Kidney Calculi
Effects of Potassium Citrate in Urine of Children With Elevated Calcium in Urine and Kidney Stones
High amounts of calcium in the urine (hypercalciuria) can cause development of kidney stones in children. Treatment for these children includes plenty of fluids, a low-salt diet and medications such as potassium citrate.
- Trial name
- NCT00120731
- Testing
- Potassium Citrate, Acetazolamide, Diet low in oxalate and purines
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Molar Incisor Hypomineralization, Oral Health
Prevalence, Etiology and Effects on Oral Health and Life Quality of Molar Incisor Hypomineralization
Molar incisor hypomineralization (MIH) can lead to many clinical conditions and affect oral health-related quality of life (OHRQoL).
- Conditions
- Molar Incisor Hypomineralization, Oral Health, Child, Only, Pediatric ALL
- Trial name
- NCT05779332
- Testing
- survey application
- Where
- Turkey (Türkiye)
- Volunteers
- 655 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Vitamin D Deficiency
Effect of Oral Daily Supplementation With 400 IU Vs 200 IU of Vitamin D in Term Healthy Neonates
The purpose of the study is to evaluate the effect of daily oral supplementation with vitamin D on serum Vitamin D levels in term healthy newborns.
- Trial name
- NCT02186028
- Testing
- Vitamin D
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Lady Hardinge Medical College
Hip; Anomaly
Examining the Effects of a Mobilization With Movement and a Dynamic Stretch With Over Pressure on Hip Flexion.
The purpose of this study is to compare the effects of a mobilization with movement (MWM) technique performed by a physical therapist with those of a dynamic stretch with over pressure on active hip flexion range of motion (ROM)…
- Trial name
- NCT04762212
- Testing
- Mobilization with movement and stretching, stretching or control
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Molar Incisor Hypomineralisation
The Effect of Salvadora Persica (Miswak) Compared to Fluoridated Toothpaste on Children's Teeth Diagnosed With Molar-Incisor Hypomineralization (MIH): A Randomized Clinical Trial
Molar-Incisor Hypo mineralization (MIH) was first described in 2001 as a developmental enamel defect . It is a condition in which the enamel of at least one first primary molar is affected with a qualitative defect causing…
- Trial name
- NCT07355465
- Testing
- Salvadora persica (miswak), Fluoridated Toothpaste
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Gaucher Disease
A Study of the Effects of Renal Impairment on the Pharmacokinetics and Tolerability of Eliglustat Tartrate
Primary Objective: To study the effect of mild, moderate, and severe renal impairment on the pharmacokinetics (PK) of eliglustat.
- Trial name
- NCT02536937
- Testing
- eliglustat
- Where
- 3 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sanofi
Ketosis, Resistance Exercise
Acute Effects of Ketone Monoester Co-Ingestion With Dietary Protein on Whole-Body Phenylalanine Oxidation, Phenylalanine Retention, and Myofibrillar Protein Breakdown Following Resistance Exercise in Older Males
The goal of this trial is to determine if ketone monoester supplementation in conjunction with protein supplementation in the post exercise period can augment whole-body protein metabolism following resistance exercise in older…
- Conditions
- Ketosis, Resistance Exercise, Dietary Protein, Aging
- Trial name
- KET-OLD-M (NCT07884513)
- Testing
- Ketone Monoester + Dietary Protein (KET+PRO), Dietary Protein (PRO), Resistance Exercise
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- McGill University
Skin Care
The Effect of Almond and Extra Virgin Olive Oils on Maintaining Skin Integrity in Neonates
This study aimed to evaluate the effects of extra virgin olive and almond oils on maintaining skin integrity in neonates admitted to the neonatal intensive care unit.
- Trial name
- NCT06286813
- Testing
- Plant (natural) oils
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Marmara University
Irritable Bowel Syndrome
A Phase 1, Randomized, Placebo-Controlled, Ascending Cohort, Dose Escalation Study in Normal Healthy Volunteers
GSK3179106 is a potent and relatively selective inhibitor of RET kinase which has been designed to be a safe and effective therapy for irritable bowel syndrome (IBS) patients .
- Trial name
- NCT02727283
- Testing
- GSK3179106
- Where
- Australia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Procedural Pain, Neonatal Hyperbilirubinemia
The Effect of Kangaroo Care on Pain in Infants Receiving Phototherapy
This study aims to evaluate and compare the effects of two different kangaroo care (KC) models on pain management in neonates undergoing phototherapy.
- Trial name
- NCT07761689
- Testing
- Kangaroo Care, Routine Care
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Marmara University
Premature Loss of Primary Teeth
Effect of Fixed and Removable Space Maintainer on Some Salivary Parameters: An In-Vivo Study
The aim of this study is to evaluate and compare the effect of lower lingual holding arch space maintainer versus removable partial denture space maintainer on some salivary parameters (salivary flow rate, pH, viscosity and…
- Trial name
- NCT06147609
- Testing
- lower lingual holding arch space maintainer, Removable partial denture space maintainer
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Long QT Syndrome, Cardiac Repolarization
Effect of Beta-blocker Therapy on QTc Response in Exercise and Recovery in Normal Subjects
Background. In congenital long QT syndrome type 1 (LQT1), episodes of ventricular tachycardia are usually triggered by exercise and can be prevented in most patients by beta-blocker therapy.
- Trial name
- NCT00588965
- Testing
- Propranolol LA
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Aspiration of Blood in Newborn
Simulation-Based Training Program Effect on Pediatric Nurses Regarding Heel-Prick Screening Test
This study aimed to assess the impact of simulation-based training on pediatric nurses' knowledge and performance regarding the heel-prick technique used during newborn blood screening tests in select hospitals in Saudi Arabia…
- Trial name
- NCT06685471
- Testing
- Screeing test
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Abeer Abd Elwahed Almowafy
Barth Syndrome
Resistance Exercise in Barth Syndrome
Barth syndrome (BTHS) is a disorder that is characterized by heart failure, exercise intolerance and skeletal muscle weakness. Preliminary evidence demonstrates that endurance exercise training does not significantly improve…
- Trial name
- NCT01629459
- Testing
- Resistance exercise and protein supplementation
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Skin Laxity
Bipolar RF Microneedling for Improved Laxity and Lift of the Submental and Neck Tissue and Effect on Elastin
This study is being conducted to evaluate the safety and efficacy of bipolar fractional radiofrequency treatment via use of the Profound System to achieve lift in lax submental (beneath the chin) and neck tissue
- Trial name
- NCT04245696
- Testing
- Dermal Handpiece / SubQ Handpiece
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Candela Corporation
Romano-Ward Syndrome, Long QT Syndrome
Evaluation of the Effects of KCNQ1 Mutation on Insulin Tolerance and Obsessive Compulsive Features in Long QT Romano-Ward Syndrome Patients.
The objectives of the study are to investigate if KCNQ1 mutation in Romano-Ward long QT patients can be associated with changes in insulin regulation and with psychological features of compulsivity, impulsivity and behavioural…
- Conditions
- Romano-Ward Syndrome, Long QT Syndrome, Compulsive Behavior, Healthy Individuals
- Trial name
- PRIME (NCT04715256)
- Testing
- Cognitive assessment of obsessive-compulsive and impulsive behaviours, Genomic analysis, Glucoregulation assessment
- Where
- 2 sites in France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Biotrial
Interventions Pain
The Effects on Pain of Acupressure and Foot Reflexology Before Heel Lancing in Newborns
This study aimed to determine the effects of foot reflexology and acupressure on the KI3 and St36 points on pain during interventions when these procedures were administered before heel lancing in term newborns.
- Trial name
- NCT04643730
- Testing
- Acupressure methods, Foot Reflexology Methods, Control Grup
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
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