Clinical trials: Effect of Sleep Deprivation
Sleep Deprivation
Age-related Changes in Sleep-wake Regulation
A sleep deprivation protocol combined with state-of-the-art, simultaneous positron emission tomography and magnetic resonance spectroscopy imaging will be employed to investigate the effects of sleep deprivation and aging on…
- Trial name
- NCT03813082
- Testing
- Prolonged wakefulness
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Sleep Deprivation
Effect of Sleep Restriction on Decision Making and Inflammation
hypothesis: sleep restriction in healthy subject trigger alteration of decision making associated with immuno-inflammatory changes inclusion criterias: healthy subjects, men, under 35 years, BMI<26, no sleep troubles…
- Trial name
- NCT01989741
- Testing
- Sleep restriction
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche Biomedicale des Armees
Healthy
Effects of Donepezil and Memantine on Cognitive Functions After a Sleep Deprivation Challenge in Healthy Volunteers
The aim of this study is to assess the utility of sleep deprivation as a potential model for prediction of clinical efficacy using a combination of cognitive physiological endpoints.
- Trial name
- NCT01461174
- Testing
- Modafinil, Donepezil, Memantine
- Where
- 2 sites in France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Qualissima
Sleep Deprivation
The Effects of Night Call on Intellectual Performance
The purpose of the current proposal will be to examine the clinical performance of both physicians in training as well as experienced faculty in pre and post call situations.
- Trial name
- NCT02697266
- Testing
- No intervention
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Haleh Saadat
Sleep Deprivation, Menstrual Cycle
The Effects of Night Shift Work on Health Across the Menstrual Cycle
The study aims to investigate the effects of sleep deprivation on women's health across different phases of the menstrual cycle.
- Conditions
- Sleep Deprivation, Menstrual Cycle, Brain Health, Metabolism
- Trial name
- MENSLEEP (NCT06683248)
- Testing
- Investigate sleep deprivation
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Sleep Deprivation
Cardiovascular Effects of Partial Sleep Deprivation
Background: Sleep curtailment is common and is associated with increased mortality due to cardiovascular causes. However, the mechanisms are not completely understood.We hypothesized that partial sleep deprivation caused however…
- Trial name
- NCT00669513
- Testing
- Partial sleep deprivation
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Sleep Deprivation, Mental Competency
Transcranial Electrical Stimulation (TES) at Slow Oscillation (SO) Frequency During NREM Sleep
The purpose of this study is to determine if the enhancement of electroencephalographic (EEG) slow-wave activity using transcranial electrical stimulation (TES) at Slow Oscillation (SO) frequency, during a restricted period of…
- Trial name
- NCT02945501
- Testing
- NeuroConn DC Stimulator PLUS
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Sleep, Sleep Deprivation
Effects of Sleep Deprivation on Blood Hormones and Inflammatory Status After Exercise Induced-muscle Damage
The aims of this study are examine the effects of sleep deprivation in muscle recovery after a maximum eccentric resistance exercise session performed on an isokinetic dynamometer (24 series of 10 repetitions).
- Trial name
- NCT02082600
- Testing
- Sleep deprivation, Normal sleep
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Delayed-onset Muscle Soreness, Sleep
Sleep and Delayed-onset Muscle Soreness
There is a need for further experimental research in order to gain a more in-depth understanding of this vicious cycle of pain and sleep disorders.
- Conditions
- Delayed-onset Muscle Soreness, Sleep, Pain
- Trial name
- NCT06699186
- Testing
- Sleep, Non-sleep
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Sleep Deprivation
Combined Effects of Acute Sleep Restriction and Moderate Acceleration (+Gz) on Physiological and Behavioral Responses to High Mental Workload
Fighter pilots have to perform tasks requiring high mental workload during moderate-intensity acceleration phases (2 to 3G) that can last several minutes.
- Trial name
- CogPhyAero (NCT06017882)
- Testing
- Partial sleep deprivation
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Sleep Deprivation
Study of Single Doses of HBS-104 in Acutely Sleep-deprived Healthy Participants
This is a study to evaluate the pharmacodynamic effects, safety, tolerability, and pharmacokinetics of HBS-104 in acutely sleep-deprived healthy adult participants.
- Trial name
- NCT07848659
- Testing
- HBS-104
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Harmony Biosciences Management, Inc.
Shift-Work Related Sleep Disturbance, Sleep Deprivation
Light Intervention for Adaptation to Night Work
The project will contribute with new knowledge concerning how aspects of the physical work environment (lighting conditions) can be arranged to facilitate the workers' adaptation to night work.
- Conditions
- Shift-Work Related Sleep Disturbance, Sleep Deprivation, Sleep
- Trial name
- NCT03203538
- Testing
- LED-light, 1000 lux, LED-light, 100 lux, LED-light, 7000 K
- Where
- Norway
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Sleep Deprivation
Effect of Sleep Deprivation on Sensory Integration of Balance, Fall Risk and Postural Stability
Sleepiness caused by sleep deprivation may increase the risk of injuries and damages during physical activity. Individual data so far indicates worsening of postural stability and control with females exhibiting better static…
- Trial name
- NCT05170191
- Testing
- Sleep Deprivation
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Sleep Deprivation
The Effects of Sleep Deprivation on Physiological and Perceptual Responses During Exercise
Sleep deprivation has been found to impact exercise performance. The effects of both partial (several hours) and full (24+ hours) sleep deprivation on exercise performance has shown effects on rating of perceived exertion, rate…
- Trial name
- NCT05313932
- Testing
- Sleep deprivation
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Prostatic Neoplasms
The Effects of Castration on the Pharmacokinetics of Zolpidem After Single Dose Administration In Men With Prostate Cancer Undergoing Androgen Deprivation Therapy Compared to Normal Healthy Females
Background: Insomnia is associated with difficulty sleeping. The drug zolpidem is widely prescribed for insomnia. Women have reported worse effects from the drug than men.
- Trial name
- NCT03436745
- Testing
- Zolpidem, ECG
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Sleep Deprivation
Physiologic Effects of Sleep Restriction
Evidence suggests a relationship between sleep deprivation and cardiovascular disease. The investigators wish to determine whether 9 nights of modest sleep restriction results in activation of cardiovascular disease mechanisms…
- Trial name
- NCT01433315
- Testing
- sleep restriction
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
We Investigated the Effect of Sleep Deprivation on the Tear Film and Ocular Surface.
Sleep Deprivation Reduces Tear Secretion and Impairs the Tear Film
Tear film consists of three layers including outer lipid layer, aqueous layer and inner mucin layer.1,2 Lipid layer protects the aqueous layer of tear film from evaporation and mucin layer adhere the tear film to ocular surface.
- Trial name
- NCT02026986
- Testing
- sleep deprivation
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hallym University Medical Center
Depression, Unipolar
Neural Mechanisms Underlying the Antidepressant Effects of Sleep Deprivation
From 40 to 60% of patients with depression experience a rapid and significant improvement of mood with one night of sleep deprivation (SD). The neural mechanisms underlying this effect have not been elucidated.
- Trial name
- NCT03169543
- Testing
- Sleep deprivation
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Sleep, Diet
Effect of CBT Intervention to Improve Sleep on Wellbeing, Dietary Intake and Food Preference
The study aims to investigate the effects of Cognitive Behavioural therapy intervention on sleep and it's effects on well-being, dietary intake and food preferences during COVID-19.
- Conditions
- Sleep, Diet, Well Being
- Trial name
- NCT04576260
- Testing
- Cognitive Behavioural Therapy for Insomnia
- Where
- 2 sites in United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Caffeine, Placebo
Caffeinate Chewing Gum on Ice Hockey Performance
The purpose of this study was to examine the impact of caffeinated chewing gum on the physical performance of elite ice hockey players in a partial sleep deprivation state.
- Trial name
- NCT06557655
- Testing
- caffeinate chewing gum
- Where
- Taiwan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University