Clinical trials: Effectiveness
Dental Caries
Impact of Detecting Initial and Active Caries Lesions in Primary Teeth
The present study aims to evaluate the impact of detecting active initial caries lesions in primary teeth regarding effectiveness, cost-effectiveness, applicability (acceptability and satisfaction) and quality of life.
- Trial name
- NCT02473107
- Testing
- Advanced caries lesions detection (no activity assessment), All caries lesions detection (+activity assessment)
- Where
- Brazil
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Chronic Fatigue Syndrome., Muscular Diseases.
Clinical Trial to Evaluate the Effectiveness of Acupuncture as a Treatment in Patients Diagnosed With CFS.
background: The Chronic Fatigue Syndrome (CFS) presents many disturbances multidimensional affect holistically to people who have the disease and current management of fatigue, pain, anxiety, depression and sleep disturbances…
- Conditions
- Chronic Fatigue Syndrome., Muscular Diseases., Cognitive Impairment, Sleep Disturbances
- Trial name
- AV/AS (NCT01907711)
- Testing
- Acupuncture.
- Where
- 2 sites in Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Vall d'Hebron
To Evaluate the Impact of the Vaginal Ph and Acidification of Vaginal Misoprostol on Its Efficacy in Facilitating Induction of Mid-trimester Abortion.
Study of Effect of Vaginal ph and Acidification of Vaginal Misoprostol on Its Efficacy for Induction of Midtrimester Abortion
To evaluate the impact of the vaginal Ph and acidification of vaginal misoprostol on its efficacy in facilitating induction of midtrimester abortion.
- Trial name
- NCT01241045
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Jellyfish Stings
Effective Treatments for Jellyfish Stings
The purpose of the study is to attempt to determine which treatment from commonly used treatments is the best at reducing pain and redness of the skin after a sting from a Portuguese Man of War, Chrysaora chinensis, or Chrysaora…
- Trial name
- NCT02015195
- Testing
- Acetic Acid (5%), Sodium Bicarbonate Slurry (50%), Papain Slurry (70%)
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Stanford University
Primary Dysmenorrhea
A Trial for Evaluation of Clinical Efficacy and Safety of Healing Stone Navel Belt in Patients With Primary Dysmenorrhea
The purpose of this study is to determine whether Healing stone navel belt is safe and effective in the treatment of Primary Dysmenorrhea.
- Trial name
- Healingstone (NCT00842881)
- Testing
- Healingstone navel belt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Healingstone Co., Ltd.
Cystic Fibrosis, Biomarkers
New Markers of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Function in Sweat
The aim of the study is to identify new biomarkers of CFTR function in sweat and in sweat gland.
- Trial name
- NCT03993600
- Testing
- Sweat test (Macroduct Sweat Collection System) and skin biopsy (Punch Biopsy)
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Malaria
Study of Safety and Effectiveness of Intravenous Immunization With PfSPZ Vaccine in Healthy African Adults
Background: Malaria is caused by small germs carried by mosquitoes. People can get malaria if an infected mosquito bites them. Malaria destroys red blood cells and reduces oxygen in the blood.
- Trial name
- NCT01988636
- Testing
- PfSPZ Vaccine
- Where
- Mali
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Opioid Consumption, Postoperative, ESPB
Evaluation of the Postoperative Efficacy of Bilateral Lumbar Erector Spinae Plane Block (ESPB) in Patients Undergoing Lumbar Disc Herniation Repair Surgery
This prospective observational study aims to evaluate the efficacy of bilateral lumbar erector spinae plane (ESP) block in providing effective postoperative analgesia and its potential impact on early mobilization and length of…
- Conditions
- Opioid Consumption, Postoperative, ESPB, Postoperative Pain, Plane Blocks
- Trial name
- NCT07403734
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Abdominal Obesity, Abdominal Obesity-Metabolic Syndrome
Metabolic Effectiveness of Extracorporeal Shockwave on Abdominal Adiposity
Egyptian Ministry of Health and Population's Preventive Sector, have named obesity as one of the top contributors to the national mortality and morbidity.
- Conditions
- Abdominal Obesity, Abdominal Obesity-Metabolic Syndrome, Abdominal Obesity in Young and Middle Aged Adults
- Trial name
- NCT07686601
- Testing
- conventional balanced, low-calorie diet 1500 k/cal for 12 weeks, aerobic training program, extracorporeal shockwave therapy
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Rhinosinusitis (Diagnosis)
Silver Nanoparticle Investigation for Treating Chronic Sinusitis
Chronic rhinosinusitis is a highly prevalent disease resulting in high economic burden. Effective therapeutic options are needed. Rhinosinusitis-related biofilms are a likely contributor to recalcitrant disease.
- Trial name
- SNITCH (NCT03243201)
- Testing
- Colloidal silver nanoparticles, Purified Water
- Volunteers
- healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Alcohol Abuse
Effects of Motivational Interviewing in Prison
Motivational Interviewing (MI) is a communication style demonstrated to decrease drug and alcohol use. A five session MI intervention (BSF) was implemented in the Swedish correctional system.
- Trial name
- NCT01184612
- Testing
- Motivational Interviewing; MI
- Where
- Sweden
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
COVID-19, SARS-CoV-2
Treatment for COVID-19 in High-Risk Adult Outpatients
This is a randomized trial for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in high-risk adults not requiring hospital admission.The overarching goal of this study is to assess the…
- Trial name
- NCT04354428
- Testing
- Ascorbic Acid, Hydroxychloroquine Sulfate, Azithromycin
- Where
- 6 sites in United States
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- University of Washington
Postpartum Hemorrhage
Four Different Methods of Performing External Aortic Compression After Caesarean Section
After childbirth, bleeding from the uterus occurs, which can quickly become very profuse if the uterus does not contract. Annually, around 80000 women die because profuse bleeding associated with childbirth, mainly in low -and…
- Trial name
- KEXAC (NCT06157307)
- Testing
- Aortic compression
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Sedentary Time, Overweight and Obesity
Exercise-snacks at Work: Impact on Cardiometabolic Parameters
The main objective is to measure the effects of intense brief exercise program in the workplace of administrative staff on the cardio-metabolic health
- Conditions
- Sedentary Time, Overweight and Obesity, Work-Related Condition
- Trial name
- NCT05942144
- Testing
- Exercise-snacks program
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Avignon
Schizophrenia, Nicotine Dependence
Effects of Smoking Cues on Tobacco Craving Responses and the Reinforcing Efficacy of Cigarettes in Smokers With and Without Schizophrenia
In this study, we will compare cue-reactivity in smokers with and without schizophrenia and the influence of smoking cues on responding for cigarette puffs under a PR schedule of reinforcement.
- Trial name
- NCT00770237
- Testing
- Smoking Cues, Neutral Cues
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Gingival Recession, Gingival Recession, Localized
Free Gingival Graft Versus Connective Tissue Graft
This study wil compare FGG and CTG for recession coverage in the anterior mandibula.
- Trial name
- NCT05563428
- Testing
- Free gingival graft, Connective tissue graft
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Cervix Uteri Dilation
Effectiveness and Safety Evaluation of Aqueduct -100 Device
Evaluation of efficacy and safety of using Aqueduct -100 - Cervical Dilator Device
- Trial name
- NCT02941211
- Testing
- Aqueduct -100
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aqueduct Medical Ltd
Adolescent Idiopathic Scoliosis
Safety and Efficacy Study of Spinal Tethering
This study is an opportunity to gather long term safety and efficacy information from patients who have had their scoliosis treated via anterior vertebral body tethering (VBT).
- Trial name
- NCT02897453
- Testing
- The Spinal Tethering System
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Heat Acclimation and Thermotolerance
Chronic Exercise With Overdressing
The purpose of this study is to determine if five training sessions of exercise with overdressing can induce heat acclimation.
- Trial name
- Chronic-XO (NCT07099872)
- Testing
- Control, Overdressing
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Clinical Safety of a PBM Program
The German Patient Blood Management Network
This epidemiological trial will determine whether the implementation of a PBM program is safe and effective in terms of clinical outcome compared to a pre-implementation cohort Primary endpoint is a composite outcome comprising…
- Trial name
- NCT02147795
- Where
- 2 sites in Germany
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
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