Clinical trials: Effectiveness
Chronic Low-back Pain
Effectiveness of Cat-Cow Yoga in Managing Chronic Low Back Pain
A randomized control trial is planned to investigate the effectiveness of Cat-Cow yoga as a treatment for chronic low back pain CLBP.
- Trial name
- NCT04723225
- Testing
- Cat-Cow Yoga
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Karachi
Rheumatoid Arthritis
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Tofacitinib vs Abatacept
This study aims to evaluate the comparative risk of dementia/Alzheimer's disease onset between patients treated with medications that target specific metabolic pathways and patients treated with alternative medications for the…
- Trial name
- DREAM (NCT04529876)
- Testing
- Tofacitinib, Abatacept
- Where
- United States
- Volunteers
- 29,464 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Hyperlipidemias, Obesity
Xian-Hua-Cha for Relieving Hyperlipidemia With Obesity
In the past decades, lipid and body fat disorders become a serious global healthcare issue, especially among the obese population.
- Conditions
- Hyperlipidemias, Obesity, Body Fat Disorder
- Trial name
- NCT05632068
- Testing
- Xian-Hua-Cha
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Postoperative Pain, Acute
Effectiveness of Fentanyl-Added TAP Block in Laparoscopic Cholecystectomy
The aim of this study is to evaluate the effectiveness of adding fentanyl to the TAP block in laparoscopic cholecystectomy cases.
- Trial name
- NCT06778668
- Testing
- TAP block with bupivacaine only, TAP block with bupivacaine and fentanyl
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Uludag University
Diabetes Mellitus, Type 2
Comparative Effectiveness of POC-A1c vs the Current Standard Based on OGTT for Early Detection DM2 in Colombia
Evaluate the impact of conducting a screening questionnaire (FINDRISC) and the implementation of a point-of-care HBA1c test for those with identified risk to suffer Diabetes in ten years, to improve the proportion of patients…
- Trial name
- EDDIT-1 (NCT05440968)
- Testing
- Point of Care - Glycated Hemoglobin (A1c), Oral Glucose Tolerance Test
- Where
- Colombia
- Volunteers
- 902 people, healthy volunteers welcome
- Sponsor
- Humberto Reynales MD MSc PhD
Adherence to the Mediterranean Diet
Nutritional Status Assessment and Dietary Recommendations Program (VENREDI)
Introduction: The Mediterranean diet has been related to beneficial effects in the prevention of cardiovascular diseases and other chronic pathologies related to diet, including some types of cancer.
- Trial name
- NCT06361550
- Testing
- VENREDI group, Health education
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Facial Plane Blocks
Comparison of the Efficacy of One Level and Tow Level of Bilateral Thoracic Erector Spinae Plane Block Combined With General Anesthesia in Laparoscopic Bariatric Surgery for Obese Patients: Randomized Controlled Trial
comparison of the feasibility and efficacy of the one-level and two-level thoracic ESP block and their effect on intraoperative and postoperative analgesia in bariatric surgeries.
- Trial name
- NCT06811493
- Testing
- bilateral thoracic erector spinae plane block combined with general anesthesia in laparoscopic bariatric surgery in obese patients
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Suicide Prevention
Efficacy-Implementation Study for PC CARES in Rural Alaska
This participatory, pragmatic efficacy-implementation trial evaluates the impact of Promoting Community Conversations About Research to End Suicide (PC CARES) to evaluate Learning Circle (LC) participant outcomes (AIM#1)…
- Trial name
- NCT06658808
- Testing
- Promoting Community Conversations About Research to End Suicide
- Where
- 2 sites in United States
- Volunteers
- 1,075 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Smoking Cessation
A Video-led Smoking Cessation Intervention in Helping Male Smokers Whose Partners Got Pregnant to Quit Smoking
This study aims to use a three arms randomized clinical trial study to evaluate the effectiveness of a video-led intervention in helping male smokers whose partner got pregnant in Mainland China to quit smoking.
- Trial name
- NCT03236025
- Testing
- Video+brief smoking cessation+pamphlet, Text-message+brief smoking cessation+pamphlet, brief smoking cessation+pamphlet
- Where
- Hong Kong
- Volunteers
- 1,023 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Post Traumatic Stress Disorder
Department of Defense PTSD Adaptive Platform Trial - Intervention C - Daridorexant
This is a Phase 2 randomized, double-blinded, placebo-controlled study that will evaluate multiple potential pharmacotherapeutic interventions for PTSD utilizing an adaptive platform trial design.
- Trial name
- NCT05948540
- Testing
- Intervention C Daridorexant
- Where
- 9 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Global Coalition for Adaptive Research
Influenza Vaccine Effectiveness
A Case Control Study of the Effectiveness of Q/LAIV Versus Inactivated Influenza Vaccine and No Vaccine in Subjects 2-17 Years of Age
This is a post-marketing case-controlled study of the effectiveness of a quadrivalent live attenuated influenza vaccine (Q/LAIV/FluMist® Quadrivalent) versus Inactivated Influenza Vaccine (IIV) and No Vaccine in subjects 2-17…
- Trial name
- ICICLE (NCT01997450)
- Where
- 12 sites in United States, United Kingdom
- Volunteers
- 4,121 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Hemorrhage, Coagulation Delay
Evaluation of Novel Point of Care Coagulation System in Pregnant Women
In this study the investigators will evaluate a new point of care Quantra Hemostasis Analyzer system to assess coagulation rapidly with ease.
- Trial name
- CCPW (NCT04301193)
- Testing
- Quantra Analyzer
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Sudden Infant Death Syndrome, Shaken Baby Syndrome
The Impact of the Nurse-Led "My Baby is Safe" Educational Program
The aim of this study is to determine the effect of the My Baby is Safe Educational Program on mothers' knowledge, skills, and self-efficacy levels.The objectives of the study are to ensure that mothers acquire sufficient…
- Trial name
- NCT07037914
- Testing
- Education and Counseling, Leaflet
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Amasya University
Healthy Infants
Starter Infant Formula With Synbiotics
This randomized, double-blind, controlled intervention trial aims to evaluate the safety and efficacy of a starter infant formula supplemented with an HMO blend and a probiotic, and will provide evidence on the safety and…
- Trial name
- NCT06073652
- Testing
- Control 1st age starter infant formula, Experimental 1st age starter infant formula
- Where
- 3 sites in Philippines
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Rehabilitation, Biofeedback
Rehabilitation With Biofeedback in Neurology
The research will aim to evaluate biofeedback rehabilitation and optical oximetry assessment in neurological patients and the influence of blood parameters on the effect of the rehabilitation carried out.
- Conditions
- Rehabilitation, Biofeedback, Neurological Diseases
- Trial name
- NCT05486052
- Testing
- Evaluation of reliability, repeatability and validity of devices among healthy subjects, Biofeedback method and Health-resort based rehabilitation Health-resort based treatments supplemented with biofeedback training, Health-resort based rehabilitation Control group - health-resort based treatments, without biofeedback training.
- Where
- Poland
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Rzeszow
Tourette Syndrome
Washed Microbiota Transplantation for Tourette's Syndrome
This study aimed to evaluate the efficacy of washed microbiota transplantation in the treatment of Tourette's syndrome (TS).
- Trial name
- WMT (NCT03764748)
- Testing
- Washed Microbiota Transplantation
- Where
- 2 sites in China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Nanjing Medical University
Efficacy of Drugs in Pain Management
Dexamethasone Versus Dexmedetomidine in IPACK Block to Reduce Pain Post Arthroscopic Knee Surgeries
The investigators will test the effects of dexamethasone versus dexmedetomidine as adjuvant to bupivacaine in IPACK Block and it's direct effect in decreasing pain post operative following Arthroscopic knee surgeries
- Trial name
- NCT07024043
- Testing
- Dexamethasone versus Dexmedetomidine in IPACK Block to reduce pain post Arthroscopic knee surgeries, IPACK and multi-modal analgesic regimen
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Schizophrenia, Schizoaffective Disorder
Efficacy and Safety Study of Escitalopram Augmentation in Treatment Resistant Schizophrenia
A primary hypothesis to be explored here is that, given its pharmacodynamic profile and hypothesized mechanisms associated with schizophrenia, escitalopram will, in comparison to placebo, be effective when added to risperidone or…
- Trial name
- NCT00231335
- Testing
- escitalopram
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Emory University
Suicide, Attempted, Suicide, Fatal
Implementation of Suicide Risk Models in Health Systems
The goal of this clinical trial is to evaluate a suicide risk model in patients receiving behavioral health care treatment. The main question it aims to answer is: Does the implementation of the suicide risk model reduce suicide…
- Trial name
- NCT06060535
- Testing
- Suicide Attempt Risk Model Care Pathway
- Where
- 3 sites in United States
- Volunteers
- 394,000 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
COVID-19, Vaccine-Preventable Diseases
The Efficacy of the 2023-2024 Updated COVID-19 Vaccines Against COVID-19 Infection
The purpose of this research study is to find out how well two different 2023-2024 updated COVID-19 vaccines protect people from COVID-19 (the disease caused by the SARS-CoV-2 virus), and to determine if getting a 2023-2024…
- Conditions
- COVID-19, Vaccine-Preventable Diseases, SARS CoV 2 Infection, Upper Respiratory Tract Infection
- Trial name
- BEEHIVE (NCT06065176)
- Testing
- Novavax COVID-19 vaccine (2023-2024 formula XBB containing), Pfizer COVID-19 mRNA vaccine (2023-2024 formula XBB containing)
- Where
- United States
- Volunteers
- 1,188 people, healthy volunteers welcome
- Sponsor
- Sarang K. Yoon, DO, MOH
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