Clinical trials: Effectivity
Enhanced Recovery After Surgery (ERAS) Protocol, Colorectal Surgery
Effects of Implementing an ERAS Protocol
Introduction: Successful colorectal surgery is determined based on postoperative mortality and morbidity rates, complication rates, and cost-effectiveness.
- Conditions
- Enhanced Recovery After Surgery (ERAS) Protocol, Colorectal Surgery, Effectivity, Colorectal Neoplasms
- Trial name
- NCT06010225
- Where
- Indonesia
- Volunteers
- 84 people
- Sponsor
- Ridho Ardhi Syaiful
Efficacy, Toxicity
Apatinib for Advanced Sarcoma: Results From Multiple Institutions' Off-label Use
Anti-angiogenesis Tyrosine kinase inhibitors (TKIs) have been proved to show promising effects on prolonging progression-free survival (PFS) for advanced sarcoma after failure of standard multimodal Therapy.
- Trial name
- NCT03491371
- Testing
- Methylsulfonic apatinib
- Where
- 2 sites in China
- Volunteers
- 56 people
- Sponsor
- Peking University People's Hospital
Effectivity of RIPC in Outcomes of TAVI Procedure
Cardioprotective Effect of RIPC in Patients Undergoing TAVI
We aim to investigate whether RIPC (remote ischemic preconditioning) is effective in the TAVI setting to reduce post-procedural myocardial damage and improve patient outcome.
- Trial name
- CARE-TAVI (NCT02283398)
- Testing
- without RIPC, RIPC
- Where
- 3 sites in Germany
- Sponsor
- Institut für Pharmakologie und Präventive Medizin
Cesarean
Effects of Norepinephrine-ephedrine Combination on Maternal Hemodynamics
The aim of this study is to investigate the effect of combined use of Ephedrine and Norepinephrine on maternal hemodynamics in patients undergoing cesarean delivery under spinal anesthesia.
- Trial name
- NCT03672071
- Testing
- Ephedrine, Noradrenaline ,ephedrine+Noradrenaline)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Yuzuncu Yil University
Refractory Neoplasms
Effectivity and Safety of Irreversible Electroporation for Refractory Neoplasms in Liver and Pancreas
The pupose of this study is to evaluate the safety and efficacy of irreversible electroporation (IRE) for refractory neoplasms in liver and pancreas, the investigators used preoperative and postoperative US/CEUS/CT/MRI to assess…
- Trial name
- NCT02822066
- Testing
- Electroporation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Type2 Diabetes Mellitus
The Effectivity and Safety Study of rExenatide-4 in Chinese Type 2 Diabetes Mellitus
This research is a randomized, double-blind,controlled trial. 456 Chinese subjects with Type 2 Diabetes Mellitus will be enrolled in the trial.
- Trial name
- NCT03239119
- Testing
- rE-4 5 mcg, rE-4 10 mcg
- Volunteers
- 456 people
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Adult Acute Lymphocytic Leukemia T-cell, Lymphoma, Lymphoblastic
Treatment of Relapsed T-cell Acute Lymphoblastic Leukemia or T-lymphoblastic Lymphoma With MabCampath
This study tests the effectivity and tolerability of treatment with alemtuzumab (MabCampath) in patients with relapsed or refractory T-cell acute lymphoblastic leukemia (T-ALL) or T-lymphoblastic lymphoma.
- Trial name
- NCT00199030
- Testing
- Alemtuzumab (MabCampath), Cladribine
- Where
- Germany
- Volunteers
- 8 people
- Sponsor
- Goethe University
Cytokine Release Syndrome, CAR-T
Extracorporeal Cytokine Adsorption as Additive Treatment of CAR-T Associated Cytokine Release Syndrome (CRS)
Patients with severe CAR-T cell associated cytokine release syndrome (CRS) (defined as vasopressor dependent) will be treated with standard of care (SOC) + cytokine adsorption (6hourly for 24 hrs).
- Trial name
- CYTORELEASE (NCT04048434)
- Testing
- Cytosorb
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 34 people
- Sponsor
- Hannover Medical School
Hepatocellular Carcinoma Non-resectable, Transarterial Chemoembolization
Microwave Ablation Combined With TACE in the Treatment of Unresectable Huge Hepatocellular Carcinoma Huge
The purpose of this study was to prospectively evaluate the efficacy and safety of TACE combined with MWA in patients with huge unresectable hepatocellular carcinoma.
- Conditions
- Hepatocellular Carcinoma Non-resectable, Transarterial Chemoembolization, Microwave Ablation
- Trial name
- NCT03277716
- Testing
- TACE, MWA, MWA system
- Where
- 10 sites in China
- Volunteers
- 100 people
- Sponsor
- Fan Weijun
Lower Urinary Tract Symptoms
Voiding Class Study for Symptom Reduction and Quality of Life in Children With LUTS
Lower urinary tract dysfunction (LUTD) is a common pathology within children and shows a wide spectrum of lower urinary tract symptoms (LUTS). These symptoms have a significant impact on a child's well-being.
- Trial name
- NCT05146258
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- University Hospital, Ghent
Pediatric ALL
Propofol to Reduce the Incidence of Postanesthetic Emergence Agitation in Pediatric Patients Under General Anesthesia
This study aimed to know the effectivity of 0.5 mg/kg propofol in the end of anesthesia to reduce the incidence of postanesthetic emergence agitation in pediatric patients under general inhalation anesthesia
- Trial name
- NCT03528954
- Testing
- Propofol
- Where
- Indonesia
- Volunteers
- 54 people
- Sponsor
- Universitas Indonesia
Postoperative Cognitive Functions
Comparison of Remifentanil With Dexmedetomidine or Midazolam in Regards of Sedation Effectivity and Postoperative Cognitive Functions in Cystoscopies
The aim of the study was to compare the effects of remifentanil-dexmedetomidine and remifentanil-midazolam with mini-mental state examination (MMSE) in monitored anesthesia care (MAC) patients undergoing cystoscopy.
- Trial name
- NCT01491009
- Testing
- Remifentanil, Midazolam
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gazi University
Refractory Neoplasms
Effectivity and Safety of Endoscopic Ultrasonography-guided Laser Ablation for Refractory Neoplasms
The purpose of this study is to evaluate the safety and efficacy of endoscopic ultrasonography (EUS) guided laser ablation liver, pancreas, and retroperitoneal tumors, the investigators used preoperative and postoperative…
- Trial name
- NCT02816944
- Testing
- EUS-guided laser ablation for refractory neoplasms
- Where
- China
- Volunteers
- 80 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Sedoanalgesia
Effectivity of Bispectral Index Monitoring in Cases of Endoscopic Retrograde Cholangiopancreatography
The bispectral index (BIS) monitoring is an EEG-based method that uses electroencephalogram analysis and a complex algorithm to generate a numerical scoring 0-100 (0 flat line EEG, 100, wide awake) BIS monitoring allows…
- Trial name
- NCT03114774
- Testing
- The bispectral index (BIS) monitoring, Ramsay Sedation Scale (RSS) Score monitoring
- Volunteers
- 60 people
- Sponsor
- Istanbul Medeniyet University
Healthy Volunteers, Persons With no Known Significant Health Problems
Effectivity of Slackline-Training in Physiotherapy
Slacklines have been established in the last few years as a training equipment in sports such as climbing, skiing and others to increase postural control.
- Trial name
- NCT02218086
- Testing
- Slackline, Wobbling Board, Pre-training
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- THIM - die internationale Hochschule für Physiotherapie
Wet Age-related Macular Degeneration (wAMD)
Long-term Follow-up Study of AL-001 Ophthalmic Injection in Subjects with WAMD
This study is designed to evaluate long-term safety and efficacy of AL-001 ophthalmic injection following suprachoroidal space(SCS) administration in subjects with wAMD.
- Trial name
- NCT06718816
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Beijing Anlong Biopharmaceutical Co., Ltd.
Chronic Obstructive Pulmonary Disease
Effectivity of Inspiratory Muscle Trainer in the Chronic Obstructive Pulmonary Disease Rehabilitation Program
This study aimed to reveal the role of inspiratory muscles exercise using Inspiratory Muscle Trainer (IMT), which is a form of weight training.
- Trial name
- NCT03739879
- Testing
- Inspiratory Muscle Trainer Philips Respironics
- Where
- Indonesia
- Volunteers
- 15 people
- Sponsor
- Universitas Indonesia
The Upper Esophageal Sphincter Contraction Strength
ERAS Swallowing Rehabilitation in Elder Patients
The investigators studied that swallowing function of patients receiving the Early Recovery Accelerated Swallowing (ERAS-W program) training will recover fast than that of patients in the control group.
- Trial name
- NCT05999786
- Testing
- early rehabiliation swallowing program, not receiving early rehabilitation swallowing program
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Hepatocellular Carcinoma
Transarterial Chemoembolization (TACE) Therapy of Hepatocellular Carcinoma (HCC) With Blocking Tumor Blood Temporarily and Enhancing Perfusion
According to radiology imaging, the patients of HCC are divided into two groups(hypovascular tumor group and moderately vascular tumor group).
- Trial name
- NCT00826384
- Testing
- balloon catheter
- Where
- China
- Volunteers
- 352 people
- Sponsor
- Eastern Hepatobiliary Surgery Hospital
Pregestational Obesity (BMI > 27kg/m2), History of Polycystic Ovary Syndrome
Medical Nutrition Therapy Plus Transgestational Metformin For Preventing Gestational Diabetes In High Risk Mexican Women
Gestational diabetes mellitus is one of the most frequent complications of pregnancy, that affect between 1 to 14% of population around the world.
- Trial name
- NCT01675310
- Testing
- medical nutrition therapy + metformin, Medical nutrition therapy
- Where
- Mexico
- Volunteers
- 90 people
- Sponsor
- Instituto Nacional de Perinatologia Isidro Espinosa de los Reyes