Clinical trials: Effects, Longterm
Skeletal Muscle Physiology
Testosterone-induced Muscle Memory and Underlying Mechanisms
The purpose of this project is to investigate underlying mechanisms of testosterone- and resistance training-induced muscle hypertrophy and muscle memory in humans.
- Trial name
- NCT06188767
- Testing
- Testosterone Undecanoate
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
Caries,Dental
Long-term Effects of a Lay Health Advisor Intervention on Immigrant Children's Caries
The aim of this study was to evaluate the long-term effectiveness of a lay health advisor (LHA) intervention on immigrant children's caries and preventive behaviors.This randomized controlled trial included mother-child pairs in…
- Trial name
- NCT04562675
- Testing
- LHA intervention, brochure-only
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
To Assess Long-term Effects of COVID-19 in Patients Who Were Affected With COVID -19
Assessment of Long-term Effects (Complications) of COVID-19 in the Southern Part of Bangladesh - a Retrospective Observational Study.
An outbreak of the novel coronavirus nCoV-19 (SARS-CoV-2), responsible for the coronavirus disease-19 (COVID-19), was first detected in Hubei province, Wuhan, China, on December 31, 2019.
- Trial name
- NCT04987736
- Testing
- RT-PCR
- Where
- Bangladesh
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Sher-E-Bangla Medical College
Cognitive Function, Growth
Long-term Effects of Iron and Zinc Supplementation During Infancy on Cognitive Performance and Growth
The hypotheses of this study are: 1. Compared to children who received a placebo, children who received iron or zinc or iron and zinc combined will perform better on cognitive tests and will have better growth status at ages 8 to…
- Trial name
- FeZn_FU (NCT00824304)
- Where
- Thailand
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Focus on Healthy Infant Growth.
Infant Formula Supplemented With Probiotic Microorganisms and/or Prebiotic.
Evaluation the nutritional suitability of a based milk infant formula supplemented with friendly bacteria (probiotic microorganisms) and or nutritional fibers (prebiotic) to healthy, full term infants compare with an otherwise…
- Trial name
- NCT00836771
- Testing
- Infant Formula
- Where
- Israel
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Materna Laboratories
Urge Urinary Incontinence, Overactive Bladder
Bringing Simple Urge Incontinence Diagnosis & Treatment to Providers (BRIDGES)
Six hundred and thirty-six women diagnosed with urge urinary incontinence (UUI) by a three-item self-administered questionnaire (3IQ) will be randomized to 12 weeks of fesoterodine or matching placebo.
- Trial name
- BRIDGES (NCT00862745)
- Testing
- Fesoterodine
- Where
- 13 sites in United States
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Turner Syndrome, Hypogonadism; Ovarian
Long Term Effects of Oral Versus Transdermal Estrogen Replacement Therapy in Turner Syndrome
This 14-month, phase IV, randomized controlled crossover trial aims to compare the effects of oral versus transdermal estrogen replacement therapy (ERT) in women with Turner syndrome (TS).
- Conditions
- Turner Syndrome, Hypogonadism; Ovarian, Hormone Replacement Therapy, Estrogen Replacement Therapy
- Trial name
- NCT06570460
- Testing
- 17-beta estradiol
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Atopic Diseases
Prevention of Allergic Diseases in Infants
A multi-center, prospective, randomized, controlled, doubleblind intervention clinical Trial is performed to proof the efficiency of hydrolyzed infant formula showing a risk reduction of developing an allergy.
- Trial name
- NCT03489733
- Testing
- Hydrolyzed Formula, Control formula
- Where
- 14 sites in Bulgaria, Czechia and 8 more
- Volunteers
- 1,226 people, healthy volunteers welcome
- Sponsor
- HiPP GmbH & Co. Vertrieb KG
Breast Cancer, Cognitive/Functional Effects
Fatigue Caused by Chemotherapy in Women Who Have Undergone Surgery for Breast Cancer and in Healthy Volunteers
RATIONALE: Gathering information over time from women undergoing chemotherapy for breast cancer may help doctors learn more about mental and physical fatigue caused by treatment.
- Conditions
- Breast Cancer, Cognitive/Functional Effects, Fatigue, Long-term Effects Secondary to Cancer Therapy in Adults
- Trial name
- NCT00909662
- Testing
- assessment of therapy complications, cognitive assessment, fatigue assessment and management
- Where
- 2 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Anemia, Iron Deficiency (Without Anemia)
The Immediate and Long-term Effects of a Novel Marine-based Iron Supplement in Adult Females
The goal of this study is to identify how well a fish-based iron supplement is absorbed and to learn how many, if any, digestive related side effects are caused by ingesting the supplement.
- Conditions
- Anemia, Iron Deficiency (Without Anemia), Iron Absorption
- Trial name
- NCT07199244
- Testing
- marine-based heme iron
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
Oxidative Stress, Muscle Strength
The Long-term Effects of Oceanix™ on Resistance Training Adaptations
This study will examine the effects of Oceanix™, an antioxidant supplement, on muscle performance, immune and endocrine function, recovery and safety in participants undergoing resistance training.
- Conditions
- Oxidative Stress, Muscle Strength, Resistance Training, Body Composition
- Trial name
- NCT04136821
- Testing
- Oceanix, Resistance Training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Relation, Mother-Child, Family Conflict
Children's Learning Centers Group FNI
The purpose of this study is to compare the effects of Family Nurture Intervention in a mother-child group setting with a Standard Children's Learning Center (CLC) Program for preschool-aged children (ages 2-4.5).
- Conditions
- Relation, Mother-Child, Family Conflict, Emotional Disturbances, Behavior Problem
- Trial name
- NCT03908268
- Testing
- Family Nurture Intervention (FNI), Standard Children's Learning Center (CLC) Program
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Columbia University
Low Back Pain, Mechanical, Chronic Pain
The Long Term Effects of Online Therapeutic Neuroscience Education in Patients With Chronic Low Back Pain
This study aims to evaluate the effects of online Therapeutic Neuroscience Education (TNE) combined with a 6-week conventional physiotherapy program on pain, disability, kinesiophobia, functionality, treatment expectations, and…
- Trial name
- NCT06847763
- Testing
- Therapeutic Neuroscience Education, Conventional Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Aging
CALERIE: Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy
The purpose of this study is to test the hypothesis that two years of sustained 25% caloric restriction (CR) in men age 21-50 (inclusive) and women age 21-47 (inclusive) will slow aging and protect against age-related disease…
- Trial name
- NCT00427193
- Testing
- Caloric Restriction (CR), Control
- Where
- 3 sites in United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Duke University
Parkinson Disease
Is Long-term Use of Amantadine Effective in PD?
The investigator aims to assess whether long-term use of amantadine is effective in patients with Parkinson's disease.
- Trial name
- NCT04260581
- Testing
- Determination of drug effects through amantadine cessation
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Frail Elderly
Long-term Effects of Interventional Strategies to Prevent Cognitive Decline in Elderly.
The MAPT PLUS study is a two-year extension of follow-up of the patients included in the MAPT preventive study, after completion of the interventions. Subjects in the four groups of the MAPT study will be prospectively followed.
- Trial name
- MAPT-PLUS (NCT01513252)
- Testing
- Gröber and Buschke test
- Where
- 13 sites in France, Monaco
- Volunteers
- 1,028 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Endothelial Dysfunction, Biochemical Markers
Acute Effects of E-Cigarette Aerosol Inhalation
This study comprises a portion of a larger study designed to compare results of vascular function in non-smokers to vascular function in healthy smokers chronically exposed to nicotinized electronic cigarette aerosol versus…
- Trial name
- NCT03479203
- Testing
- Electronic Cigarette Aerosol
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Hyperlipidemia, Cardiovascular Diseases
The Effect of Strawberries in a Cholesterol-Lowering Dietary Portfolio
The purpose of this study is to determine whether addition of strawberries to a dietary portfolio of cholesterol-lowering foods will improve compliance and so increase the effectiveness of the dietary portfolio in lowering…
- Conditions
- Hyperlipidemia, Cardiovascular Diseases, Hypercholesterolemia
- Trial name
- NCT00345722
- Testing
- strawberry dietary intervention
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Bundle-Branch Block, Heart Septal Defects, Ventricular
Right Bundle Branch Block After Surgical Closure of Ventricular Septal Defect
The most common congenital heart disease is the ventricular septal defect, and after surgical closure of a such defect, an arrythmia called the right bundle branch block, is very frequent.
- Trial name
- NCT01480908
- Testing
- Echocardiography at rest, Echocardiography during exercise, MRI at rest
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Skin Pigmentation Over Contour Deformities of Face, Trauma, Rhomberg Disease
Long Term Effects on Skin Hyper Pigmentation With and Without Mesenchymal Stem Cell Enriched Adipose Tissue Grafting for "Contour Deformities With Pigmentary Changes on Face"
MSCs one injected along with fat, regulate pigmentation over the contour defects of face
- Trial name
- MSCs (NCT03564808)
- Testing
- MSC
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- King Edward Medical University