Clinical trials: Effects, Longterm
Osteoporosis
Calcium and Bone Mass in Young Females
We originally suggested that calcium in the diet is important in determining the amount of bone (bone mass) that builds up in young adults. We are testing the effect of calcium on bone mass in 354 Caucasian (white) girls.
- Trial name
- NCT00000402
- Testing
- Calcium
- Where
- United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Obesity, Overweight
Long-term Effects of Arabinoxylans on Intestinal Barrier Function
The higher prevalence of overweight and obesity among the population contributes to increased incidences of chronic metabolic diseases.
- Trial name
- NCT01877044
- Testing
- NAXUS
- Where
- Netherlands
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Parkinson Disease
Is Long-term Use of Amantadine Effective in PD?
The investigator aims to assess whether long-term use of amantadine is effective in patients with Parkinson's disease.
- Trial name
- NCT04260581
- Testing
- Determination of drug effects through amantadine cessation
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Obesity & Overweight
Long Term Effect of VLCKD on Body Composition and 24-hour Energy Metabolism
evaluation of body weight in patients with obesity after VLCKD
- Trial name
- VLCKDFU (NCT07418281)
- Testing
- follow up after very low calorie ketogenic diet
- Where
- Italy
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Postprandial Hyperglycemia
Investigation of Milk Peptides on Postprandial Blood Glucose Profile
Aim of the study is to investigate the effect of two different dosages of milk peptides on postprandial blood glucose profile in prediabetic subjects compared to placebo.
- Trial name
- NCT03932695
- Testing
- Low dose milk peptide, High Dose milk peptide
- Where
- Germany
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Ingredia S.A.
Quality of Life, Cognitive Impairment
Long Term Implications of Rare Brain Tumours'
Patients diagnosed with oligodendroglioma with a specific molecular profile represent rare tumour groups (about 10% of adult gliomas) with relatively favourable prognosis (median survival between 8 and 12 years).
- Conditions
- Quality of Life, Cognitive Impairment, WHO Grade II Oligodendroglial Tumor, WHO Grade III Oligodendroglial Tumor
- Trial name
- NCT04708548
- Testing
- Health-related Quality of Life, Psychological Distress, Fatigue
- Where
- 2 sites in Netherlands, United Kingdom
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Galina Velikova
Respiratory Function
Acute and Long-Term Effects of Integrated Myofascial Release Therapy on Respiratory Function in Healthy Adults
This study will investigate the immediate and longer-term effects of integrated myofascial release therapy on breathing-related outcomes in healthy adults.
- Trial name
- EMGT-RESP (NCT07822139)
- Testing
- Other
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Nutrition, Healthy
Acute and Long-term Health Effects of Various Carbohydrates on Blood Glucose Management in Humans
Dietary fibre, especially soluble fibre, has several health benefits such as lowering the risks for cardiovascular disease, stroke, diabetes, obesity, and gastrointestinal diseases.
- Trial name
- NCT06554002
- Testing
- Control, Treatment
- Where
- Singapore
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
eHealth, Dietary Modification
One Year Home Monitoring and Treatment of IBS Patients
The purpose of this study Is to evaluate if a 4 weeks probiotic VSL#3 treatment and a strict LFD for 4 weeks are equally good in treating IBS symptoms in IBS patients with diarrhoea or mixed predominance and further evaluate the…
- Conditions
- eHealth, Dietary Modification, Probiotics, Microbiome
- Trial name
- NCT03586622
- Testing
- Low FODMAP diet (LFD), VSL#3®
- Where
- Denmark
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Adrenal Hyperplasia, Congenital
Determining the Long-Term Effects of Prenatal Dexamethasone Treatment in Children With 21-Hydroxylase Deficiency and Their Mothers
Congenital adrenal hyperplasia (CAH) is a genetic disorder that affects the amount of steroids that the body forms. The most common form of CAH is 21-hydroxylase deficiency (21OHD), which leads to cortisol deficiency and causes…
- Trial name
- NCT00617292
- Where
- 4 sites in United States, Brazil and 1 more
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Office of Rare Diseases (ORD)
Carpal Tunnel Syndrome
Platelet Rich Plasma and Hydrodissection for Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy with involving compression of the median nerve in the carpal tunnel.
- Trial name
- NCT02986828
- Testing
- platelet rich plasma, Normal saline, Ultrasound
- Where
- Taiwan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Hyperlipidemia, Cardiovascular Diseases
Effects of a Long Term Dietary Portfolio and of Sequential Removal of Food Components From the Diet
The purpose of this study is to evaluate the long term effectiveness of the dietary portfolio, consisting of viscous fibers, soy products, nuts and plant sterols, as well as the effects of removing single food components from the…
- Conditions
- Hyperlipidemia, Cardiovascular Diseases, Hypercholesterolemia
- Trial name
- NCT00438893
- Testing
- Dietary portfolio of cholesterol-lowering foods
- Where
- Canada
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Toronto
HIV Infections, HIV Seronegativity
Long-Term Effects of HIV Exposure and Infection in Children
As new drugs and vaccines are developed to prevent HIV disease progression and prolong survival of HIV infected patients, the short-term safety and effectiveness of these treatments are evaluated in research studies.
- Trial name
- NCT00006304
- Where
- 92 sites in United States, Puerto Rico
- Volunteers
- 4,150 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Baacterial Colonization, Urinary Tract Infections
The Effect of Surface Acoustic Waves on the Prevention of Colonization in Longterm Indwelling Urinary Caatheters
This is a double blinded rct to evaluate the effect of the UroShield SAW transducer on preventing bacterial colonization in longterm indwelling catheters. The duration of the trial is 30 days.
- Trial name
- NCT03090373
- Testing
- UroShield
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Rosenblum, Jonathan I., DPM
Covid19, MIS-C Associated With COVID-19
Pediatric COVID Outcomes Study (PECOS)
This is a multisite prospective observational study to evaluate the clinical sequelae of symptomatic and asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the pediatric population, including…
- Conditions
- Covid19, MIS-C Associated With COVID-19, MIS-C Multisystem Inflammatory Syndrome in Children, SARS-CoV2 Infection
- Trial name
- NCT04830852
- Where
- 2 sites in United States
- Volunteers
- 1,097 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Endothelial Dysfunction, Biochemical Markers
Acute Effects of E-Cigarette Aerosol Inhalation
This study comprises a portion of a larger study designed to compare results of vascular function in non-smokers to vascular function in healthy smokers chronically exposed to nicotinized electronic cigarette aerosol versus…
- Trial name
- NCT03479203
- Testing
- Electronic Cigarette Aerosol
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Atopic Diseases
Prevention of Allergic Diseases in Infants
A multi-center, prospective, randomized, controlled, doubleblind intervention clinical Trial is performed to proof the efficiency of hydrolyzed infant formula showing a risk reduction of developing an allergy.
- Trial name
- NCT03489733
- Testing
- Hydrolyzed Formula, Control formula
- Where
- 14 sites in Bulgaria, Czechia and 8 more
- Volunteers
- 1,226 people, healthy volunteers welcome
- Sponsor
- HiPP GmbH & Co. Vertrieb KG
Parenting, Parent-Child Relations
Middle School Success Over Stress
It is clear that the COVID-19 pandemic has impacted families adversely in multiple ways, including economic stressors, mental health-related functioning, social/familial functioning, as well as responses to mandated safety…
- Conditions
- Parenting, Parent-Child Relations, Depression, Self-regulation
- Trial name
- MSSOS (NCT05117099)
- Testing
- Family Check-Up
- Where
- United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Frail Elderly
Long-term Effects of Interventional Strategies to Prevent Cognitive Decline in Elderly.
The MAPT PLUS study is a two-year extension of follow-up of the patients included in the MAPT preventive study, after completion of the interventions. Subjects in the four groups of the MAPT study will be prospectively followed.
- Trial name
- MAPT-PLUS (NCT01513252)
- Testing
- Gröber and Buschke test
- Where
- 13 sites in France, Monaco
- Volunteers
- 1,028 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Lateral Epicondylitis
Immediate and Longterm Effects of Mulligan Mobilization With and Without Myofascial Release on Pain,Grip Strength and Function in Patients With Lateral Epicondylitis
This study will help to determine the immediate and long term effects of Mulligan mobilization with and without myofascial release on pain, grip strength and function in patients with lateral epicondylitis
- Trial name
- NCT05566418
- Testing
- mulligan mobilization, myofascial release
- Where
- Pakistan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Lahore