Clinical trials: Effects, Longterm
Cancer Pain
Long-term Effects of Methadone for Cancer Pain
The methadone is an useful opioid for the cancer pain treatment, mostly used in second or last line during the opioid rotation. The Methadone had an anti-MNDA effect, and clinicians agree that the methadone could have an effect…
- Trial name
- NCT02856399
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
Radiation-Induced Xerostomia, Head and Neck Cancer
Trial of Acupuncture for Radiation-Induced Xerostomia in Head and Neck Cancer
This study is being done to find out what effects, good and/or bad, acupuncture has on participants and their xerostomia caused by radiation therapy for the treatment of the cancer.
- Conditions
- Radiation-Induced Xerostomia, Head and Neck Cancer, Radiation Toxicity, Oral Complications of Chemotherapy and Head/Neck Radiation
- Trial name
- ACUPUNCTURE (NCT02589938)
- Testing
- Standard Oral Hygiene, Standard Oral Hygiene + True Acupuncture
- Where
- 36 sites in United States
- Volunteers
- 258 people
- Sponsor
- Wake Forest University Health Sciences
Premature Births
Long-term Effect of The Mother Infant Transaction Program (MITP)
The purpose of this study is to investigate if a cost and time effective intervention in a previous RCT for preterm infants and their parents can reduce the parents experience of concern and stress, and improve the childrens…
- Trial name
- 2007/2/0150 (NCT00903149)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Ullevaal University Hospital
Obesity, Diabetes
Fibre and Appetite Regulation Trial (FART)
High intake of cereal fibre has been shown to be associated with reduced weight gain and improved insulin sensitivity. We hypothesize these effects are due to the short chain fatty acids derived from the bacterial fermentation…
- Trial name
- NCT00247455
- Testing
- Low fibre breakfast cereal (puffed rice/cornflakes), High fibre cereal (All Bran/Bran Flakes)
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Fabry Disease
Open-Label Extension Study of the Long-Term Effects of Migalastat HCL in Patients With Fabry Disease
This is an open-label extension study intended to provide continued treatment with migalastat hydrochloride (HCl) for participants with Fabry disease who completed treatment of a previous migalastat HCl study.
- Trial name
- NCT02194985
- Testing
- migalastat HCl 150 mg
- Where
- 28 sites in United States, Argentina and 13 more
- Volunteers
- 84 people
- Sponsor
- Amicus Therapeutics
Postoperative Residual Curarization
Muscle Relaxants and Post-Anesthesia Complications
This Germany-wide, multi-center, epidemiologic study is designed to evaluate the incidence of post-operative/anesthesia effects of muscle relaxants (i.e.
- Trial name
- PORC (NCT00753389)
- Testing
- None (anesthesia)
- Where
- Germany
- Volunteers
- 20,000 people
- Sponsor
- Technical University of Munich
Chronic Obstructive Pulmonary Disease
Long-term Effects of Non-invasive Ventilation in Hypercapnic Chronic Obstructive Pulmonary Disease (COPD) Patients
In this multicenter study the comparison of the mass flow distribution and redistribution versus the relative blood flow per lobe (as a surrogate for Ventilation/ Perfusion (V/Q) matching) with functional respiratory imaging…
- Trial name
- NCT01592656
- Testing
- Functional Respiratory Imaging, Lung compliance measurement, Non-invasive ventilation (Respironics)
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 40 people
- Sponsor
- FLUIDDA nv
Bariatric Surgery Candidate, Weight Loss
Long Term Effect of Bariatric Surgery on Pelvic Floor Disorders
Bariatric surgery is increasingly practiced, as it is the most efficient treatment for morbid obesity. More than eighty percent of the operated patients are women.
- Trial name
- ICONES (NCT04575987)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 709 people
- Sponsor
- Poitiers University Hospital
Myelofibrosis
A Long-Term Study of the Effects of Orally Administered SAR302503 in Patients With Myelofibrosis
The purpose of this study is to evaluate the long-term effects of orally administered SAR302503 (TG101348) in patients with myelofibrosis who have completed the MF-TG101348-001 study.
- Trial name
- NCT00724334
- Testing
- SAR302503 (TG101348)
- Where
- 6 sites in United States
- Volunteers
- 43 people
- Sponsor
- Bristol-Myers Squibb
Multidirectional Instability, Hypermobility Spectrum Disorder
Impact of Neuromuscular Control With and Without Electrical Stimulation and Long-term Effect of Kinetic Chain Exercises in Multidirectional Shoulder Instability Patients
Background: Shoulder instability is commonly observed in adolescents and young females, ranging from asymptomatic multidirectional instability (MDI) to symptomatic conditions.
- Conditions
- Multidirectional Instability, Hypermobility Spectrum Disorder, Electrical Stimulation, Neuromuscular Control
- Trial name
- NCT07611006
- Testing
- neuromuscular eletrical stimulation, neuromuscular control training
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Sepsis
A Study on How the Immune System Responds to Sepsis and Its Long-term Effects
Sepsis occurs when an infection, caused by bacteria, a virus, or a fungus, enters the body and throws the immune system out of balance.
- Trial name
- HEAL-SEPSIS (NCT07273344)
- Testing
- blood sampling
- Where
- Netherlands
- Volunteers
- 400 people
- Sponsor
- Radboud University Medical Center
Metaverse, Virtual Reality
Metaverse- and VR-Supported Education in a Digital Breastfeeding Museum: Long-Term Effects on Breastfeeding Process, Self-Efficacy, and Motivation
This randomized controlled prospective study aimed to evaluate the long-term effects of Metaverse- and virtual reality (VR)-supported education provided in a digital breastfeeding museum on the breastfeeding process…
- Conditions
- Metaverse, Virtual Reality, Digital Museum, Breastfeeding Education
- Trial name
- NCT07516041
- Testing
- Training Supported by Metaverse and Virtual Reality (VR) in the Digital Breastfeeding Museum Group, Virtual Reality Headset (Meta Quest 2)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Uludag University
Breast Neoplasms
Breast Cancer Long-term Outcome of Cardiac Dysfunction
The purpose of this study is to assess the prevalence of cardiac dysfunction and (undiagnosed) heart failure in women registered in general practice with a history of breast cancer who received chemotherapy and / or radiotherapy…
- Trial name
- BLOC (NCT01904331)
- Where
- Netherlands
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Coronary Artery Disease
Effect of Cranberry Juice on Endothelial Function
A pilot study of 15 subjects will be completed to determine whether acute consumption of cranberry juice has an effect on endothelial function.
- Trial name
- NCT00553904
- Testing
- Cranberry juice
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Boston University
Dental Biofilm pH
In Vivo Study of Sucrose and Liquid Oral Pediatric Medicines of Long-term Effect on Dental Biofilm pH
The aims of this study were to determine the sucrose and liquid oral pediatric medicines of long-term effect on dental biofilm pH to evaluate the cariogenic potential in vivo.
- Trial name
- SPMedicines (NCT01819350)
- Testing
- G1, G2 and G3, G4 and G5
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Respiratory Tract Infections
Long Term Effect of General Practitioner Education on Antibiotic Prescribing
Respiratory tract infections are the most common indication for antibiotic prescribing in primary care. Several studies have shown a strong relationship between antibiotic use and bacterial resistance.
- Trial name
- PAAIR2 (NCT01107223)
- Testing
- Experimental: Training to antibiotic prescription, No education on antibiotic prescription rules.
- Where
- France
- Volunteers
- 170 people
- Sponsor
- Henri Mondor University Hospital
Malaria
Early Childhood Malaria Prevention With Maloprim in The Gambia
A trial was conducted in the 1980s to compare two strategies for control of malaria in young children aged 3-59 months: treatment with chloroquine versus treatment combined with fortnightly chemoprophylaxis with Maloprim.
- Trial name
- NCT00294580
- Testing
- Maloprim
- Where
- The Gambia
- Volunteers
- 2,253 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Preterm Infants
Food Habit Programming: Influence of Genetics and Early Nutrition in a Population of Preterm Infants
Influence of neonatal nutrition and growth on psychomotor development of 2 years preterm infants.-Joint influence of environmental factor (early nutrition) and genetics factors on feeding behaviour setting- up in a particular…
- Trial name
- Polynuca (NCT00663572)
- Where
- France
- Volunteers
- 234 people
- Sponsor
- Nantes University Hospital
Hypertrophic Cardiomyopathy, Left Ventricular Hypertrophy
Long Term Effects of Enalapril and Losartan on Genetic Heart Disease
The human heart is divided into four chambers. One of the four chambers, the left ventricle, is the chamber mainly responsible for pumping blood out of the heart into circulation.
- Conditions
- Hypertrophic Cardiomyopathy, Left Ventricular Hypertrophy, Myocardial Ischemia
- Trial name
- NCT00001534
- Testing
- Losartan
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Long-term Effects Secondary to Cancer Therapy in Adults, Lymphoma
Observation in Patients With Diffuse Large B-Cell Non-Hodgkin's Lymphoma Treated on Clinical Trial CAN-NCIC-LY9
RATIONALE: Treatment for diffuse large B-cell non-Hodgkin's lymphoma may cause side effects and secondary cancers later in life.
- Trial name
- NCT00400907
- Testing
- clinical observation, management of therapy complications
- Volunteers
- 667 people
- Sponsor
- German High-Grade Non-Hodgkin's Lymphoma Study Group