Clinical trials: Effects, Longterm
Colonic Diverticuar Disease, Defecatory Functions
Effects of Inferior Mesenteric Artery Preservation in Laparoscopic Colorectal Resection for Diverticular Disease.
This is a prospective randomized study aimed to verifying the short and long-term results of inferior mesenteric artery preservation following colorectal resection for diverticular disease
- Conditions
- Colonic Diverticuar Disease, Defecatory Functions, Fecal Incontinence, Constipation
- Trial name
- EIMAP (NCT06506552)
- Testing
- IMA preserving, IMA sectioning
- Volunteers
- 300 people
- Sponsor
- University of Roma La Sapienza
Depression Mild, Depression Moderate
Long-term Effects ReSet Your Mind - Mechanisms
See: ClinicalTrials.gov ID: NCT05402150 Relevant for this Paper: This investigation aims to evaluate the stability of the effectiveness of different two-week online interventions in a four months follow-up regarding reward…
- Trial name
- NCT06072209
- Testing
- Behavioral Activation, Mindfulness and Gratitude, Combination of Behavioral Activation and Mindfulness and Gratitude
- Where
- Germany
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Type 2 Diabetes, Obesity
Effects of Caloric Restriction in Obesity and Type 2 Diabetes
The study investigates whether a long-term 25% caloric restriction can prevent onset and/or progression of renal function deterioration, retinal involvement and cardiovascular complications in overweight/obese type 2 diabetic…
- Trial name
- CRESO2 (NCT01930136)
- Testing
- Calorie restriction (25%), Ad libitum health diet
- Where
- Italy
- Volunteers
- 103 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Limb Injury, Older Adults
Geriatric Trauma Care Program for Living Alone Older Adults With Injuries
To examine the long-term effects of the Geriatric Trauma Care Program (GTCP) regarding pain, functional disability, depression, loneliness, and health-related quality of life among older adults with traumatic injuries who live…
- Conditions
- Limb Injury, Older Adults, Geriatric, Pain
- Trial name
- NCT06902636
- Testing
- Geriatric trauma care program
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Kaohsiung Medical University
Asymptomatic Condition
Long Term Effects of Different Dietary Protocols on Determinants of Health in Patients' Lymphocytes
Food choices and eating habits play an important role in the management of common noncommunicable diseases, i.e. diabetes type II, hypertension, metabolic syndrome and others.
- Trial name
- FTIR (NCT05377164)
- Testing
- food choices
- Where
- Slovenia
- Volunteers
- 12 people
- Sponsor
- University of Primorska
Coronary Artery Disease, Percutaneous Coronary Intervention
Study of the Long-term Effects of P2Y12 Inhibitor Monotherapy and Coagulation Markers After Percutaneous Coronary Angioplasty.
Patients who undergo percutaneous coronary intervention (PCI) are commonly treated with antiplatelet therapy to prevent stent thrombosis and recurrence of events.
- Conditions
- Coronary Artery Disease, Percutaneous Coronary Intervention, Acute Coronary Syndromes, Antiplatelet Therapy
- Trial name
- HI-TECH 2 (NCT07582835)
- Testing
- Clopidogrel, Ticagrelor, Prasugrel
- Where
- Switzerland
- Volunteers
- 355 people
- Sponsor
- Cardiocentro Ticino
COVID-19
Self-Management Interventions for Long COVID-19
The purpose of this study is to investigate and compare the feasibility and efficacy of two group-based interventions (education vs. mindfulness) to help self-manage Long-COVID symptoms.
- Trial name
- NCT05268523
- Testing
- Education and Strategies Intervention, Mindfulness Skills Intervention
- Where
- Canada
- Volunteers
- 270 people
- Sponsor
- Toronto Rehabilitation Institute
Antimicrobial Resistance (AMR), Oral Microbiota
Salivary Microbiota and Antimicrobial Resistance in Relation to Chlorhexidine Use
This study evaluated the ecological effects of 0.06% chlorhexidine toothpaste on the salivary microbiota of healthy individuals, focusing on taxonomic composition, functional shifts, and prevalence of predicted antimicrobial…
- Conditions
- Antimicrobial Resistance (AMR), Oral Microbiota, Oral Microbiome Health, Chlorhexidine
- Trial name
- SMARCH (NCT07570927)
- Testing
- 0.06% Chlorhexidine Digluconate Toothpaste
- Where
- 2 sites in Czechia
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Obstructive Sleep Apnea
CPAP Effect on Vascular Function in Obstructive Sleep Apnea
Obstructive sleep apnea syndrome is responsible of endothelial dysfunction, which is a independent cardio-vascular risk factor. Assessment of pulse wave velocity (PWV) and peripheral arterial tone (PAT) are study measurements of…
- Trial name
- VNI-SOH2 (NCT02623088)
- Testing
- PAP Therapies (CPAP)
- Where
- France
- Volunteers
- 107 people
- Sponsor
- University Hospital, Grenoble
Metabolic Health
Effects of Exercise During Pregnancy on the Long-term Metabolic Health of Mothers and Their Offspring
The aim of this study was to assess the long-term metabolic effects of gestational exercise on overweight and obese women and their offspring 8-10 years post-intervention.
- Trial name
- NCT07435857
- Testing
- exercise
- Where
- China
- Volunteers
- 221 people
- Sponsor
- Peking University First Hospital
Age-Related Macular Degeneration, Retinal Function
Ranibizumab Short- and Log-term Effects on Retinal Function in wAMD
Multifocal-electroretinoram (ERG) and microperimetry are objective criteria to asses retinal function. No information besides visual acuity exist for the development of retinal function during the course of wet AMD during therapy…
- Trial name
- LucERG (NCT01269151)
- Testing
- Lucentis (Ranibizumab)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Luebeck
Chronic Pelvic Pain Syndrome, Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Effects of Pelvic Floor Training in Male Chronic Pelvic Pain, Correlation Between Subjective and Objective Outcomes
The goal of this randomized controlled study is to establish the long-term effect of pelvic floor re-education using biofeedback and home training for men with chronic pelvic pain.
- Conditions
- Chronic Pelvic Pain Syndrome, Chronic Prostatitis With Chronic Pelvic Pain Syndrome, Chronic Prostatitis, Pelvic Floor; Relaxation
- Trial name
- NCT06115083
- Testing
- Pelvic floor re-education using bio-feedback and home training
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Region Stockholm
Obesity, Weight Loss
Long-Term Effect of 10 mg Versus 20 mg Rimonabant in Overweight or Obese Patients
The primary objective of this study is to assess, over a period of 12 months, the effect on weight loss and weight maintenance of rimonabant 10 mg in comparison with rimonabant 20 mg in overweight/obese patients after an initial…
- Trial name
- MODERATO (NCT00678483)
- Testing
- rimonabant (SR141716)
- Where
- 5 sites in Croatia, Finland and 3 more
- Volunteers
- 331 people
- Sponsor
- Sanofi
Covid19
Long-term Effects of COVID-19: a Comparative Cohort Study
This study is a longitudinal cohort study which investigates the effect of COVID-19 in ambulatory care. This study aims to assess the effect of COVID-19 beyond the acute phase, i.e.
- Trial name
- CoCo (NCT05002205)
- Testing
- Questionnaires, spirometry, ECG
- Volunteers
- 180 people
- Sponsor
- KU Leuven
Hamstring Tightness
IASTM vs. Static Stretching for Hamstring Tightness: Short- and Long-Term Effects
This study compares two treatments for people with tight hamstring muscles (the muscles at the back of the thigh): instrument-assisted soft tissue mobilization (IASTM) and static stretching.
- Trial name
- IASTM-HT (NCT07838844)
- Testing
- Instrument-Assisted Soft Tissue Mobilization, Static Stretching
- Volunteers
- 46 people
- Sponsor
- GÖKHAN MARAŞ
Osteoporosis, Post-Menopausal
Long Term Effects of Raloxifene Treatment on Bone Quality
This is a cross-sectional study to determine, via iliac crest bone biopsies, the effect of long-term treatment with raloxifene on histomorphometry and bone quality in patients who participated in the Continuing Outcomes Relevant…
- Trial name
- NCT00532428
- Testing
- Raloxifene
- Where
- 7 sites in United States, Mexico and 2 more
- Volunteers
- 31 people
- Sponsor
- Eli Lilly and Company
Pain, Postoperative
US-guided Ilioinguinal Blocks Versus Local Infiltration
Injection of local anesthetic drugs is an effective way to freeze (block) nerves to achieve loss of sensation during surgery and satisfactory pain control afterwards.
- Trial name
- NCT01871181
- Testing
- Ilioinguinal block, Local infiltration
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Parkinson's Disease
A Study of AP-CD/LD in Fluctuating Parkinson's Disease Patients Who Completed IN 11 004
The purpose of this study is to allow evaluation of long-term clinical effect and safety outcome of treatment with AP-CD/LD, as well as to allow patients to benefit from extended treatment duration with AP-CD/LD after they have…
- Trial name
- NCT02615873
- Testing
- Accordion Pill™ Carbidopa/Levodopa
- Where
- 85 sites in United States, Bulgaria and 8 more
- Volunteers
- 460 people
- Sponsor
- Intec Pharma Ltd.
Disorder of Circulatory System, Metabolic Disease
Investigation of Long-term Effects of CarelessTM on Microcirculation
Aim of the study is to investigate long-term effects of CarelessTM, a Mangifera indica fruit powder on microcirculation and endothelial function after supplementation of 4 weeks.
- Trial name
- NCT02588313
- Testing
- Mango fruit powder
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Vital Solutions Swiss AG
Knee Osteoarthritis
The Combination Effect of Platelet-rich Plasma and Hyaluronic Acid for Knee Osteoarthritis
Although platelet rich plasma (PRP) and Hyaluronic acid (HA) are beneficial for osteoarthritis of knee (OA knee), the combined effect of PRP with HA was not clear so far.
- Trial name
- NCT03290365
- Testing
- platelet rich plasma + Hyaluronic acid, platelet rich plasma + normal saline
- Where
- Taiwan
- Volunteers
- 46 people
- Sponsor
- Tri-Service General Hospital (TSGH)