Clinical trials: Effects of Vibration, active
Stroke (CVA) or TIA
Functional Electrical Stimulation Versus Whole-Body Vibration in Post-Stroke Rehabilitation
This study will compare the effects of Functional Electrical Stimulation (FES) and Whole Body Vibration Training (WBVT) on lower limb motor control, balance, and physical performance in post-stroke patients.
- Trial name
- NCT07629882
- Testing
- Functional Electrical Stimulation, Whole Body Vibration Training
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Vibration on Patellofemoral Joint Pain After ACLR
Anterior cruciate ligament (ACL) injury is a prevailing problem among sports participants, especially in non-contact sports. Studies have reported that 70-84% of ACL injuries are non-contact in nature, and movements like changing…
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Patellofemoral Pain
- Trial name
- NCT05501210
- Testing
- WBV, PEMF
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Pulmonary Arterial Hypertension
Spironolactone for Pulmonary Arterial Hypertension
Background: High blood pressure in the lungs, known as pulmonary arterial hypertension (PAH), is a rare disorder. In spite of recent advances in treatment, the death rate remains unacceptably high.
- Trial name
- NCT01712620
- Testing
- Spironolactone
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Stroke, Ischemic
Evaluation and Prediction of the Effect of EECP on HR-NICE Patients
Stroke is one of the most threatening causes of mortality and disability worldwide. High risk non-disabling ischemic cerebrovascular events (HR-NICE), defined by mild stroke complicating with greater than 50% atherosclerotic…
- Trial name
- NCT05718622
- Testing
- real EECP
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Heart Failure, AV Block
Synchrony in Cardiac Conduction: Assessing the Effects of Pacing on Cardiac Performance Through Magnetic Resonance Imaging and Advanced ECG-imaging
Rationale Right ventricular pacing (RVP) is an established and effective therapy for patients with atrioventricular (AV) block. However, frequent RVP has been associated with left ventricular (LV) dyssynchrony and may progess…
- Trial name
- HARMONY (NCT06843135)
- Testing
- Ventricular pacing
- Volunteers
- 88 people
- Sponsor
- Amsterdam UMC, location VUmc
Chronic Non Specific Low Back Pain
Effects of Whole-Body Vibration and Pilates on Pain, Dynamic Balance, and Functional Performance in Chronic Non-Specific Low Back Pain
Chronic non-specific low back pain (CNSLBP) affects pain, balance, and functional ability. This randomized clinical trial aims to compare the effects of whole-body vibration (WBV) and Pilates, both combined with conventional…
- Trial name
- NCT07719699
- Testing
- Whole body vibration, Pilates
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Postpartum Pelvic Girdle Pain
Hypopressive-Core Stabilization With and Without Whole-Body Vibration in Postpartum Pelvic Girdle Pain
Pregnancy-related pelvic girdle pain is one of the most frequent musculoskeletal complications of pregnancy and the postpartum period.
- Trial name
- NCT07920406
- Testing
- Hypopressive-core stabilization exercises combined with whole-body vibration, hypopressive and core stabilization
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Management and Technology Lahore
Irritable Bowel Syndrome
Pilot Study of the Physiological Effects of an Integrative Medicine Approach in Irritable Bowel Syndrome
Although underutilized, what is emerging as one of the best ways of evaluating inflammation in the body, particularly in difficult to observe regions, is through the use of Fluorodeoxyglucose (FDG) positron emission tomography…
- Trial name
- IBS (NCT03370614)
- Testing
- IBS Group, Healthy Control Group
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
fMRI Research, Transcranial Magnetic Stimilation
The Relationships Between Neural Correlates of Effort Perception and Physical Activity Engagement
Objectives and research hypothesis Physical inactivity is a major health concern that has been linked to a variety of chronic diseases, including obesity, diabetes, cancer, cardiovascular diseases, and mental disorders.
- Conditions
- fMRI Research, Transcranial Magnetic Stimilation, EEG Brain Oscillations, Motor Task
- Trial name
- EffortLESS (NCT06691490)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Metabolic Abnormalities, Obesity & Overweight
Effects of Sequential Therapy With Mexidol® (Intravenous) and Mexidol® FORTE 250 (Oral) on Functional Brain Activity Assessed by Functional Magnetic Resonance Imaging and Biochemical Parameters in Patients With Chronic Cerebral Ischemia: A Comparison of Patients With and Without Metabolic Disorders
We aim to elucidate the metabolic and neuroactive properties of sequential Mexidol therapy in patients with and without cerebrometabolic disorders using blood biomarkers, anthropometry and brain functional MRI (task- and rest).
- Conditions
- Metabolic Abnormalities, Obesity & Overweight, Cerebral Atherosclerosis, Cerebrovascular Disease
- Trial name
- MIF (NCT07923240)
- Testing
- Mexidol sequential therapy
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Research Center of Neurology, Russia
Diabetes Mellitus, Type 2
Effects of Vibration-Assisted Physical Activity in Type-2 Diabetes
The World Health Organization ranks Saudi Arabia as having the 7th highest rate of type-2 diabetes in the world. This therefore makes diabetes the most challenging health problem facing Saudi Arabia.
- Trial name
- VIBRANT-KSA (NCT07350473)
- Testing
- Localized vibration, Usual care
- Volunteers
- 305 people
- Sponsor
- University of Central Lancashire
Multiple Sclerosis, Relapsing-Remitting
Investigating the Effect of Ocrelizumab in African Americans and Caucasians With Relapsing Multiple Sclerosis
The investigators intend to examine the effects of ocrelizumab use in African American multiple sclerosis disease course compared to Caucasian disease course utilizing imaging measures with magnetic resonance imaging (MRI) and…
- Trial name
- NCT04458688
- Testing
- Observation of Ocrelizumab as Treatment in RRMS Patients
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Wayne State University
Stroke
Task-Oriented Upper Limb Training With Focal Vibration in Stroke
This study aims to investigate the effects of task-oriented upper limb training combined with focal vibration on hand function, proprioception, and muscle tone in patients with stroke.
- Trial name
- NCT07558876
- Testing
- Task-oriented upper limb training combined with focal vibration, Active Comparator: Task-Oriented Upper Limb Training Alone
- Where
- 2 sites in South Korea
- Volunteers
- 38 people
- Sponsor
- Jisu Kim
Schizophrenia
The Effects of Auditory Stimulation During Sleep on Brain Networks in Schizophrenia
In this research study the investigators will use sleep headbands to measure brain rhythms and to improve their coordination across brain regions. The headbands will be worn at home for multiple nights.
- Trial name
- NCT06386588
- Testing
- Closed loop auditory stimulation during sleep
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
MRI-related Anxiety, MRI Completion Rate
Effect of IE Glasses on MRI Patient Outcomes
Examine the effect of immersive entertainment glasses (IEG) on patients' claustrophobia-associated anxiety levels during magnetic resonance imaging (MRI).
- Trial name
- NCT07660952
- Testing
- Immersive entertainment glasses, Standard of Care: Anesthesia, Standard of Care: Sedative
- Volunteers
- 300 people
- Sponsor
- Baptist Health South Florida
Schizophrenia;Schizoaffective
The Effects of Non-invasive Brain Stimulation on Treatment Adherence in Schizophrenia
This study seeks to explore the effects of transcranial direct current stimulation (tDCS), a non-invasive method of brain stimulation, as an adjunctive treatment to improve antipsychotic medication adherence in patients with…
- Trial name
- NCT04033679
- Testing
- Active TDCS
- Where
- Canada
- Volunteers
- 106 people
- Sponsor
- Centre for Addiction and Mental Health
Subacromial Pain Syndrome
Effects of Corrective External Support and Regional Vibration Applications in Subacromial Pain Syndrome
Sixty three individuals with chronic subacromial pain syndrome will be included in our study. In the evaluations to be made to the participants; Pain intensity will be measured with the Visual Analogue Scale (VAS), joint movement…
- Trial name
- NCT06409442
- Testing
- Standard Physiotherapy Program, Kinesio Taping, Local Vibration Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Dokuz Eylul University
Cerebral Palsy (CP)
Local Vibration for Drooling in Children With Cerebral Palsy
This randomized-controlled trial evaluates local vibration therapy for drooling and orofacial muscle biomechanics in children with cerebral palsy.
- Trial name
- NCT07626424
- Testing
- Local Vibration Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Bitlis Eren University
Stroke, Healthy
Effects of Vibration on Motor Function of Survivors of Chronic Stroke
The aim of this study is to evaluate how vibration of the tendons enhances arm and hand training in survivors of chronic stroke.
- Trial name
- NCT06663501
- Testing
- Assisted Motion with Enhanced Sensation training
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Transcranial Direct Current Stimulation, Post-Concussion Syndrome
Effects of tDCS for Enhancing Cognitive Function in Individuals With Persistent Post-Concussion Syndrome
Globally, 10 million new traumatic brain injury (TBI) cases are estimated annually, with mild traumatic brain injury (mTBI) accounting for 75-90% of all TBI cases.
- Conditions
- Transcranial Direct Current Stimulation, Post-Concussion Syndrome, Functional Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy
- Trial name
- NCT06376500
- Testing
- tDCS with cognitive training programme
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The Hong Kong Polytechnic University