Clinical trials: Ejaculatory Dysfunction
Premature Ejaculation
The Impact and Benefit of Physical Activity on Premature Ejaculation
The purpose of this study is to investigate the relationship between physical activity and PE, and determine whether moderate physical activity might delay ejaculation time or be an alternative treatment for PE.
- Trial name
- PE (NCT02844998)
- Testing
- physical activity, dapoxetine 30 mg on demand
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara Training and Research Hospital
Premature Ejaculation
Brain Activity During Sexual Behavior in Patients With Primary Premature Ejaculation a Clinical Trial
This is a controlled study of patients with and without primary premature ejaculation. It is based on near-infrared spectroscopy (NIRS) functional brain imaging to detect and compare changes in brain activity in resting and task…
- Trial name
- NCT06570135
- Testing
- Detecting Brain Activity with Functional Near Infrared Spectroscopy
- Where
- 2 sites in China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Premature Ejaculation, Cognitive-Behavior Treatment
Efficacy of a New Behavioral Treatment for Premature Ejaculation Using a Masturbation Aid Device: Star-Stop 3.0
The present study included 57 patients ≥18 years who met diagnostic criteria for PE including intravaginal ejaculatory latency time (IELT) of ≤2 minutes and had a Premature Ejaculation Diagnostic Tool (PEDT) score ≥11.
- Conditions
- Premature Ejaculation, Cognitive-Behavior Treatment, Masturbation Aid Device
- Trial name
- NCT03304808
- Testing
- Exercise Programme +device+ lubricant, Exercise Programme + lubricant
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Instituto Sexológico Murciano
Ejaculatory Dysfunction, Premature Ejaculation
Ejaculatory and Orgasmic Dysfunction Registry
The goal of this observational study is to evaluate the safety and efficacy of various therapies used to treat ejaculatory and/or orgasmic dysfunctions in men.
- Conditions
- Ejaculatory Dysfunction, Premature Ejaculation, Delayed Ejaculation, Anorgasmia
- Trial name
- NCT06605469
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Charitable Union for the Research and Education of Peyronie's Disease
Ejaculation Delayed
A Clinical Investigation to Assess the Effectiveness of Benzocaine Condoms in Healthy Adult Men
This investigation is designed to evaluate the effectiveness of two NRL condoms with Benzocaine paste compared with a standard NRL control.
- Trial name
- NCT05255770
- Testing
- Test condom A (NRL condom with 5% benzocaine paste), Test condom B (NRL condom with 3% benzocaine paste), Control NRL condom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Premature Ejaculation
Evaluation of the Safety and Effectiveness of the vPatch Device
Multi-center, international, prospective, randomized, double-blind, two-arms, sham-controlled, first-in-human clinical investigation.
- Trial name
- NCT03942367
- Testing
- Active Device (vPatch)
- Where
- 3 sites in Israel, Italy
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Virility Medical Ltd.
Obstetric Labour, Premature, Premature Ejaculation
A First Time in Human Study in Healthy Male Volunteers for Compound GSK557296.
A study conducted on healthy volunteers to determine the safety, tolerability and affect on the human body by experimental drug GSK557296.
- Trial name
- NCT00549211
- Testing
- GSK557296
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Premature Ejaculation, Ejaculation
Effect of Prostatic Urethra and Seminal Vesicle Morphometry on Ejaculation
The goal of this observational study is to learn whether the size and shape of the prostatic urethra and seminal vesicles - measured on multiparametric prostate MRI (mpMRI) - are related to premature ejaculation (PE) severity in…
- Trial name
- NCT07614854
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Premature Ejaculation
A New Treatment for Premature Ejaculation?
The aim of study is to determine if they can produce increases in the IELT using a masturbator in subjects with premature ejaculation, producing improvements in the quality and satisfaction of the sexuality of the patient.
- Trial name
- NCT02297152
- Testing
- FLIP HOLE
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Instituto Sexológico Murciano
Delayed Ejaculation
Penile Nerve Stimulation for Treatment of Delayed Ejaculation
The aim of this clinical trial is to test the safety and feasibility of using transcutaneous electrical nerve stimulation (TENS) of the penile nerves to reduce intra-vaginal ejaculatory latency time in men with delayed…
- Trial name
- NCT04115540
- Testing
- TENS penile nerve stimulation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Stanford University
Ejaculation Delayed
A Clinical Investigation to Assess the Effectiveness of Benzocaine in NRL Condoms in Healthy Adult Men Who Feel They Ejaculate Too Quickly During Vaginal Sex
The investigation is to evaluate the effectiveness of benzocaine in two NRL condoms compared with a standard NRL control without benzocaine in prolonging time to ejaculation in healthy adult men who feel they ejaculate too…
- Trial name
- NRL (NCT05840172)
- Testing
- Test condom A (NRL condom with 5% benzocaine paste), Test condom B (NRL condom with 3% benzocaine paste), Control NRL condom
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Premature Ejaculation
Study to Evaluate Efficacy and Safety in Male Subjects With Premature Ejaculation
The purpose of this clinical trial is to test an experimental drug therapy called Tramadol Hydrochloride (HCl) Orally Disintegrating Tablets (ODT) ("Tramadol HCl ODT" or the "study drug").
- Trial name
- NCT00983736
- Testing
- Tramadol Hydrochloride
- Where
- 48 sites in Bulgaria, Czechia and 3 more
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Ejaculatory Dysfunction
Exploration of eJaculatory Anatomy Concept Study (EJAC Study)
Ejaculatory dysfunctions (ED) are an important cause of postoperative dissatisfaction, which lead to a decrease in the intensity of orgasms in 50% of patients.
- Trial name
- NCT05650853
- Testing
- Transrectal ultrasound, Urethroscopy
- Where
- France
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Clinique Pasteur
Premature Ejaculation
Safety and Efficacy of Escitalopram in the Treatment of Premature Ejaculation
Escitalopram has been claimed to have the highest selectivity for the human serotonin transporter relative to the noradrenaline or dopamine transporters. This might be associated with greater clinical efficacy.
- Trial name
- NCT00656552
- Testing
- Escitalopram
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Premature Ejaculation
Vagus Nerve Stimulation in Premature Ejaculation
Introduction: Premature ejaculation (PE), one of the most common sexual dysfunctions in men, negatively affects sexual function and quality of life.
- Trial name
- NCT07300774
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Vitamin D, Vitamin B12 and Folic Acid Among Patients With Premature Ejaculation
Assessment of Serum Levels of Vitamin D, Vitamin B12 and Folic Acid Among Patients With Lifelong Premature Ejaculation and Non-responding to Dapoxetine Treatment.
Therefore, this study will aim to assess serum levels of vitamin D, vitamin B12 and folic acid among patients with lifelong PE and non-responding to dapoxetine treatment.
- Trial name
- PE (NCT04355949)
- Testing
- Serum vitamin D, vitamin B12, folic acid
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Sexual Behavior, Erectile Dysfunction
Male Reproductive Health of Floating Population: a Large-Scale Survey in Dongguan
To determine the prevalence of sexual problems particularly premature ejaculation and erectile dysfunction among men working in factories of Dongguan city, using the self-rating scales like International Index of Erectile…
- Conditions
- Sexual Behavior, Erectile Dysfunction, Premature Ejaculation
- Trial name
- NCT01901029
- Where
- China
- Volunteers
- 3,100 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Premature Ejaculation
A Safety and Tolerability of PSD502 (a Topical Anesthetic) in the Treatment of Premature Ejaculation
A phase I, single-center, double-blind, randomized, placebo-controlled, safety and pharmacokinetic study to evaluate systemic and local vaginal exposure to lidocaine and prilocaine and the metabolites, 2,6-dimethylaniline…
- Trial name
- NCT01184105
- Testing
- Intervention A, Intervention B
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Plethora Solutions Ltd
Premature Ejaculation
THE IMPACT OF VITAMIN B12 TREATMENT ON EJACULATORY FUNCTIONS IN MEN: SYMPTOMATIC RELIEF AND IMPROVED OUTCOMES
Aim: To investigate whether intramuscular B12 treatment has an effect on ejaculation in male patients with B12 deficiency. Methods: Male patients who were diagnosed with vitamin B12 deficiency in the internal medicine outpatient…
- Trial name
- VITAMIN B12 (NCT07036497)
- Testing
- Vitamin B12
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- OZGUR EKICI
Premature Ejaculation
Chronotype and Premature Ejaculation
Chronotype (or circadian preference) has previously been shown to be associated with sexual attitudes and behaviors and is an important factor affecting sexual satisfaction.
- Trial name
- NCT04841395
- Testing
- Intravaginal ejaculatory latency time (IELT), Arabic Index of Premature Ejaculation (AIPE), Morningness-Eveningness Questionnaire (MEQ)
- Where
- Turkey (Türkiye)
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital