Clinical trials: Elder
Breast Cancer Metastatic, Breast Cancer Survival
21-gene in Elder Breast Cancer Patients With Lymph Node Metastasis
This study is a single-center, bidirectional cohort study. It aims to include 35 elderly (≥65 years old) Luminal A type breast cancer patients with axillary lymph node metastasis after surgery as the research subjects.
- Trial name
- QiluElderHope (NCT06891651)
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Qilu Hospital of Shandong University
Depression
Mental Health Intervention for Elderly Abuse Victims
There is no current elder abuse service that systematically assesses and provides services to address the mental health needs of older adult abuse victims.
- Trial name
- PROTECT (NCT02283385)
- Testing
- PROTECT
- Where
- 2 sites in United States
- Volunteers
- 63 people
- Sponsor
- Weill Medical College of Cornell University
Postoperative Confusion
Effects of Dexmedetomidine on Postoperative Cognitive Dysfunction During One-lung Ventilation in Elder Patients
This study is to explore the effects of dexmedetomidine on postoperative cognitive dysfunction during one-lung ventilation in elder patients.
- Trial name
- NCT02134093
- Testing
- Induction of anesthesia,midazolam ,sufentanil,etomidate and rocuronium, Dexmedetomidine, Normal saline
- Volunteers
- 120 people
- Sponsor
- Tang-Du Hospital
Dementia
PLAN: Dementia Literacy Education and Navigation for Korean Elders With Probable Dementia and Their Caregivers
Early detection of dementia allows for a transition to early dementia care that may delay or slow deterioration of cognitive functions and functional disabilities and enable families to adequately plan for the potential…
- Trial name
- PLAN (NCT03909347)
- Testing
- PLAN, Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 574 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Congestive Heart Failure
Empowering Elders Through Technology
Telehomecare is a technology that individuals use in their homes to communicate with health providers electronically. This technology can help them function at a higher level and avoid undesirable hospitalizations by making…
- Trial name
- NCT00261664
- Testing
- telehomecare
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- Robert Wood Johnson Foundation
Osteoporosis, Bone Loss
Zoledronic Acid for Osteoporosis in the Elderly
This trial will examine the safety, efficacy and feasibility of a single dose of intravenous zoledronic acid in the maintenance of skeletal integrity for frail, institutionalized women, who are most at risk for the deleterious…
- Conditions
- Osteoporosis, Bone Loss, Fragility Fractures
- Trial name
- ZEST (NCT00558012)
- Testing
- Intravenous zoledronic acid, Vitamin D 800 IU/daily, Calcium 1200 mg/daily
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- University of Pittsburgh
Multimodal Intervention, Fragility
Effectiveness of a Multi-component Physical Training in Hyper-fragile Elders: A Randomized Clinical Trial
Objective: To compare short-term and medium-term effectiveness of a multimodal program that integrates a program of therapeutic exercise, medication review, adequacy of diet and health education, compared with standard medical…
- Conditions
- Multimodal Intervention, Fragility, Other Metabolic Diseases, Physical Activity
- Trial name
- PowerA-01 (NCT02772952)
- Testing
- Control Intervention, Multimodal Intervention
- Where
- Spain
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Malaga
Depression, Dementia
Home-delivered Intervention for Depressed, Cognitively Impaired Elders
Among older adults the combination of depression, cognitive impairment (memory problems), and disability contribute to a worsening of physical and mental health and to poor treatment outcomes.
- Conditions
- Depression, Dementia, Geriatrics
- Trial name
- NCT01350349
- Testing
- Problem Adaptation Therapy (PATH), Supportive Therapy
- Where
- 2 sites in United States
- Volunteers
- 134 people
- Sponsor
- Weill Medical College of Cornell University
Type 2 Diabetes
The Benefits of Intensive Glycemic Control in Elderly Patients With Type 2 Diabetes
Aims/hypothesis: Populations worldwide are aging and type 2 diabetes is common in individuals aged >80 years. The important issue that needs to be considered is whether tight glycemic control is benefits for elderly patients with…
- Trial name
- NCT00850798
- Testing
- Intensive glycemic control, Conservative glycemic control
- Where
- Taiwan
- Volunteers
- 208 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Post Operative Cognitive Dysfunction
Elder Surgery - Functional Recovery Following Beta Blockade
This study proposes a prospective randomized study of elders undergoing elective major abdominal surgery to assess recovery following a unique anesthetic regimen incorporating a adrenergic receptor antagonist.
- Trial name
- NCT00507663
- Testing
- Atenolol
- Where
- 3 sites in United States
- Volunteers
- 359 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Chronic Obstructive Pulmonary Disease
Warm Homes for Elder New Zealanders
Aim The purpose of this study is to evaluate whether fuel subsidies reduce exacerbations of COPD among people aged over 55, and therefore whether providing such subsidies is a cost-beneficial policy initiative.
- Trial name
- WHEZ (NCT01627418)
- Testing
- Energy Voucher, No intervention : control arm
- Where
- 3 sites in New Zealand
- Volunteers
- 522 people
- Sponsor
- University of Otago
The Upper Esophageal Sphincter Contraction Strength
ERAS Swallowing Rehabilitation in Elder Patients
The investigators studied that swallowing function of patients receiving the Early Recovery Accelerated Swallowing (ERAS-W program) training will recover fast than that of patients in the control group.
- Trial name
- NCT05999786
- Testing
- early rehabiliation swallowing program, not receiving early rehabilitation swallowing program
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Elder Mistreatment, Elder Abuse
Knowledge and Interpersonal Skills to Develop Enhanced Relationships (KINDER)
The Knowledge and Interpersonal Skills to Develop Enhanced Relationships (KINDER) intervention was developed to prevent psychological elder abuse (EA) and promote high-quality caregiving by lowering relationship strain and…
- Conditions
- Elder Mistreatment, Elder Abuse, Quality of Care, Dementia
- Trial name
- KINDER (NCT07216950)
- Testing
- Knowledge and Interpersonal Skills to Develop Enhanced Relationships, Healthy Living for the Caregiver
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Mood Disorders, Depression
Promoting Widowed Elders Lifestyle After Loss
This study is for adults 60 years and older who are grieving the recent loss of a spouse or partner. Bereavement is one of the most distressing transitions faced by older adults and triggers dramatic changes to older adults'…
- Conditions
- Mood Disorders, Depression, Anxiety, Grief
- Trial name
- NCT02631291
- Testing
- Behavioral self-monitoring, Behavioral self-monitoring + Motivational interviewing
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Denture, Removable Partial Denture
Effectiveness of an Ultrasonic Denture Hygiene Intervention Program Among Community-dwelling Elders
Objectives: The objective of this study was to assess prospectively the effectiveness of ultrasonic denture hygiene interventions in improving denture cleanliness among community-dwelling elders.
- Conditions
- Denture, Removable Partial Denture, Denture Cleansers, Cetylpyridinium Chloride
- Trial name
- NCT03522272
- Testing
- Ultrasonic cleaning, Conventional denture hygiene
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Elderly, Exercise Training
The Effect of an Online Exercise Course on the Increase of Elders' Regular Exercise Intention
The effect of an online exercise course on the increase of elders' regular exercise intention.
- Trial name
- NCT05445739
- Testing
- The effect of an online exercise course on the increase of elders' regular exercise intention
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cancer
Comprehensive Geriatric Assessment and Management for Canadian Elders With Cancer
A multicentre two-group parallel single-blind (outcome assessor) randomized controlled trial (RCT). A cost effectiveness study alongside a clinical trial using a payer and societal perspective to study the cost-effectiveness of…
- Trial name
- NCT03154671
- Testing
- Geriatric assessment and management
- Where
- 2 sites in Canada
- Volunteers
- 351 people
- Sponsor
- University of Toronto
Influenza
A Clinical Trial With Influenza A/H1N1 Vaccines
A single center, stratified, randomized and double-blind phase IV clinical trial is to be conducted in healthy elders (equal to or more than 61 years), adults (18-60 years), adolescents (12-17 years) and children (3-11 years) to…
- Trial name
- NCT00956111
- Testing
- split-virion, adjuvanted H1N1 vaccine of 7.5 μg per dose, split-virion, adjuvanted H1N1 vaccine of 15 μg per dose, split-virion, non-adjuvanted H1N1 vaccine of 15 μg per dose
- Where
- China
- Volunteers
- 1,614 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
Fall, Healthy Aging
Validity and Reliability of a Depth Camera-based Automated Physical Function and Fall Risk Assessments
Falls significantly reduce physical function as well as quality of life which leads to failure of successful aging among elders.
- Trial name
- NCT06519864
- Testing
- Azure Kinect-based Tandem Stance Test (ATST) and Physical Therapist's Measurements of Tandem Stance Test (PTST), Azure Kinect-based Five Times Sit-to-Stand Test (AFTSS) and Physical Therapist's Measurements of Five Times Sit-to-Stand Test (PFTSS), Azure Kinect-based Timed Up and Go Test (ATUG) and Physical Therapist's Measurements of Timed Up and Go Test (PTUG)
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sahmyook University
Balance; Distorted
PNFand Perturbations Based Exercises on Balance Training in Elder Population
To compare the effects of proprioceptive neuromuscular facilitation techniques and perturbation-based balance training on risk of falls and quality of life in elderly population.65 to 85 years old age both male and female…
- Trial name
- NCT05086211
- Testing
- proprioceptive neuromuscular facilitation, pertubation based balance training
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University