Clinical trials: Elderly Cancer Patients
Leukemia
CMA-676 in Treating Older Patients With Acute Myeloid Leukemia in First Relapse
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of CMA-676 in treating older patients who have acute…
- Trial name
- NCT00003673
- Testing
- chemotherapy, gemtuzumab ozogamicin
- Where
- 10 sites in United States
- Volunteers
- 55 people
- Sponsor
- Pfizer
Colorectal Cancer, Fatigue
Physical Activity Intervention for Older Patients During Chemotherapy for Colorectal Cancer
This study will see if patient who undergo a physical activity intervention called Walk With Ease report experiencing less fatigue and a higher quality of life during chemotherapy for colorectal cancer than those who do not…
- Trial name
- NCT02191969
- Testing
- Walk With Ease
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Metastatic Renal Cell Carcinoma
Sorafenib in Elderly Patients With Metastatic Renal Cell Carcinoma
Study Design This is a multicenter, open label, first line phase II study in elderly (≥ 65 years old) metastatic Renal Cell Carcinoma (mRCC) patients not suitable for any other currently approved treatment (bevacizumab+INF…
- Trial name
- SERCC (NCT01342627)
- Testing
- Sorafenib
- Where
- Italy
- Volunteers
- 4 people
- Sponsor
- Centro di Riferimento Oncologico - Aviano
Vascular Access Complication
Effectiveness of the Rapid Intravascular Start (RIVS) System Versus Conventional Catheter
The study will test a hypothesis that the RIVS system will have a higher rate of successful first PIV placement compared to conventional catheter without a significant increase in complications and time of procedure.
- Trial name
- NCT00914069
- Testing
- RIVS vascular access, Conventional vascular access
- Where
- 3 sites in United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- C. R. Bard
Lung Cancer Patients
Global, Regional, and National Burdens and Trends of Tracheal, Bronchial, and Lung Cancer in Individuals Aged 70 Years and Older from 1990 to 2021
Despite the increasing health burden of tracheal, bronchial, and lung (TBL) cancer patients aged ≥ 70 years worldwide, data on its burden and trends are limited.
- Trial name
- GDBlung70 (NCT06694194)
- Volunteers
- 111,627 people
- Sponsor
- Hongquan Xing
Oncology, Aging
Geriatric Oncology Follow-up in the Alpine Valley
As the french population is ageing, the question of medical care in elderly cancer patients is fundamental. A third of all cancer patients are 70 years or older.
- Trial name
- SONGAlp (NCT03349229)
- Where
- France
- Volunteers
- 4,000 people
- Sponsor
- University Hospital, Grenoble
Breast Cancer
Optimal Surgical Approach for Early-Stage Breast Cancer in Chinese Patients Aged ≤ 40 Years: a Cohort Study
The optimal surgical treatment option (BCS+RT versus MAST) for young patients with early-stage breast cancer remains debated. The present study aims to explore trends in surgical management and compare survival outcomes between…
- Trial name
- NCT06603805
- Testing
- MAST group, breast-conserving surgery plus adjuvant radiotherapy
- Volunteers
- 974 people
- Sponsor
- West China Hospital
High Risk Acute Myeloid Leukemia
Phase III Study of CPX-351 Versus 7+3 in Patients 60-75 Years Old With Untreated High Risk (Secondary) Acute Myeloid Leukemia
To confirm the efficacy of CPX-351 compared to 7+3 as first line therapy in elderly patients (60-75 yrs) with high risk (secondary) Acute Myeloid Leukemia. The primary efficacy endpoint will be overall survival.
- Trial name
- 301 (NCT01696084)
- Testing
- CPX-351, 7+3 (cytarabine and daunorubicin)
- Where
- 43 sites in United States, Canada
- Volunteers
- 309 people
- Sponsor
- Jazz Pharmaceuticals
Ovarian Cancer, Epithelial Ovarian Cancer
Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT
The purpose of this study is to see whether participants who are assigned to a multimodal prehabilitation intervention during chemotherapy are able to adhere with exercise and nutrition program to prepare for their cancer surgery.
- Conditions
- Ovarian Cancer, Epithelial Ovarian Cancer, Pancreatic Adenocarcinoma
- Trial name
- NCT06412510
- Testing
- Prehabilitation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Case Comprehensive Cancer Center
Acute Myeloid Leukemia
Gemtuzumab Ozogamicin+Cytarabine vs Idarubicin+Cytarabine in Elderly Patients With AML.Mylofrance 4
Purpose : The main objective of this study is to assess the efficacy and tolerance of the addition of repeated doses of low doses (3mg/m2) of Gemtuzumab Ozogamicin (GO) in addition with standard doses of Ara-C in previously…
- Trial name
- ALFA1401 (NCT02473146)
- Testing
- Gemtuzumab ozogamicin (GO)
- Where
- 21 sites in France
- Volunteers
- 225 people
- Sponsor
- Versailles Hospital
Diffuse Large B-cell Lymphoma
Trial of R-GemOx Regimen in Previously Untreated Elderly Patients With DLBCL.
The purpose of this study is to investigate efficacy and safety of GemOx(Gemcitabine and Oxaliplatin) combination with rituximab(R) as first-line treatment of elderly patients with DLBCL
- Trial name
- NCT01670370
- Testing
- R-GemOx
- Volunteers
- 60 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Acute Myeloid Leukemia
A Patient-Centered Communication Tool (UR-GOAL) Versus Usual Care for Older Patients With Acute Myeloid Leukemia, Their Caregivers, and Their Oncologists
The objective of this study is to evaluate the preliminary efficacy of the UR-GOAL tool in improving shared decision making and communication between older patients with AML and their oncologists in a pilot randomized trial.
- Trial name
- UR-GOAL 2 (NCT05335369)
- Testing
- UR-GOAL
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- University of Rochester
Octogenarian Patients With Non-metastatic Resectable Colorectal Cancer
SGA-OCRC: Prediction of 90-Day Major Adverse Postoperative Outcomes in Octogenarians With Resectable Colorectal Cancer
Octogenarian patients with colorectal cancer are a growing population with substantial heterogeneity in frailty, functional reserve, nutritional status, and comorbidity.
- Trial name
- NCT07903129
- Volunteers
- 1,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Colorectal Neoplasms, Prostatic Neoplasms
Determinants of Quality Of Life in AGEd Cancer Patients
Patients face multiple stresses and challenges in the aftermath of cancer diagnosis. Despite needs perceived by elderly patients might differ from those of younger patients, there is a paucity of published data assessing the…
- Trial name
- DEQOLAGE (NCT02672657)
- Where
- 3 sites in France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Esophageal Cancer
Chemoradiation Plus Iparomlimab Consolidation in Older With ESCC
This study was conducted in elderly (≥70 years old) patients with locally advanced esophageal squamous cell carcinoma (ESCC). Aim to evaluate the efficacy and safety of Iparomlimab consolidation therapy following concurrent…
- Trial name
- NCT07038629
- Testing
- S1, Iparomlimab, Radiation
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Acute Myeloid Leukemia
Optimizing Induction Chemotherapy Regimens for ND Elderly AML Patients Who Are Eligible for Intense Chemotherapy
The optimal induction chemotherapy regimen for newly diagnosed elderly AML patients who are eligible for intense chemotherapy is currently not well defined.
- Trial name
- NCT06066242
- Testing
- Different induction chemotherapy regimens
- Where
- China
- Volunteers
- 113 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Quality of Life, Primary Patient Caregiver
Perceived Burden and Quality of Life of Primary Caregivers of Cancer Patients Aged 70 and Older After 5 Years of Management
Cancer is a disease that requires long-term management, especially now that medical advances have transformed most cancers from an acute to a chronic condition.
- Conditions
- Quality of Life, Primary Patient Caregiver, Cancer
- Trial name
- FARAPPAC (NCT04478903)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Acute Myeloid Leukemia
Study of Low-Dose Intravenous Decitabine in Patients Aged > 60 Years With Acute Myeloid Leukemia
This study is an open-label phase II trial to investigate the efficacy and toxicity of low-dose decitabine (5-aza-2'-deoxycytidine) in elderly patients with acute myeloid leukemia (AML) not eligible for aggressive induction…
- Trial name
- NCT00866073
- Testing
- Decitabine 15 mg/m2 i.v.
- Where
- 8 sites in Germany, Netherlands
- Volunteers
- 238 people
- Sponsor
- University Hospital Freiburg
Breast Cancer, Colorectal Cancer
Assessment of Outpatient Digital Follow-up of Patients Over 70 Years of Age Undergoing Chemotherapy Treatment
adherence of digital follow-up in a population of elderly patients.
- Conditions
- Breast Cancer, Colorectal Cancer, Lung Cancer
- Trial name
- E-SN@P PROJECT (NCT03959774)
- Testing
- IPC NET
- Where
- 4 sites in France
- Volunteers
- 119 people
- Sponsor
- Institut Paoli-Calmettes
Cancer, Geriatric
The Effect of Walking on Fatigue After Chemotherapy in Patients 65 and Older
This study will look at the impact of a self-directed walking program on post-chemotherapy survivors experiencing fatigue. It is hypothesized that the walking program will help lessen fatigue.
- Conditions
- Cancer, Geriatric, Fatigue
- Trial name
- S-PACT (NCT02191982)
- Testing
- Walk With Ease
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.