Clinical trials: Elderly Exercise
Physical Conditioning, Human, Cognition
Effects of Aerobic Exercise on Cognitive Function and Brain-derived Neurotrophic Factor in Young Adults
The present study will investigate the effects of aerobic exercise on cognition and growth factors including brain-derived neurotrophic factor (BDNF) in young adults aged 15-21 years.
- Trial name
- NCT02075944
- Testing
- High intensity aerobic exercise, Low intensity aerobic exercise
- Where
- Denmark
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Nutritional Intervention
The Effect of Ingesting a Novel Algae Protein Source on Rested and Exercised Muscle Protein Synthesis Rates in Older Adults.
To assess the rested and postexercise muscle protein synthetic response following the ingestion of a flavourless algae protein source compared with whey protein in older adults.
- Trial name
- CALM (NCT06852547)
- Testing
- protein
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Old Age; Debility
Effectiveness of 8 Week Multicomponent Exercise Program in Older Adults With Frailty and Cognitive Impairment
Multicomponent exercise program in a frail population. It is analyzed whether there is an improvement in different parameters of the daily life of the study subjects, analyzing the variables of: physical condition, fragility…
- Trial name
- GERYPHYSIO (NCT06440733)
- Testing
- Multicomponent exercise program focused in elderly.
- Where
- Spain
- Volunteers
- 17 people
- Sponsor
- University of Malaga
Sedentary Behavior, Aging
Oral 'Breath Test' to Measure Anabolic Sensitivity in Young and Older Adults at Different Activity Levels
Recent work in the investigators laboratory has examined the ability of a non-invasive 13CO2 breath-test to assess differences in amino acid oxidation rates and net balance in young healthy males following protein feeding and…
- Conditions
- Sedentary Behavior, Aging, Sarcopenia, Amino Acids
- Trial name
- ARBT (NCT05216809)
- Testing
- Habitual Physical Activity, Step-Reduction
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Old Age; Debility
Multicomponent Exercises in Functional Performance and Cognitive Ability of Hospitalized Elderly
Older patients spend most of their time in situations of muscle disuse during acute hospitalization. Physical inactivity is a key factor for the development of adverse events caused by hospitalization, known as iatrogenic…
- Trial name
- NCT05317338
- Testing
- Group-based exercise training during hospitalization
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Sedentary Lifestyle
Reducing Sedentary Behavior vs. Increasing Physical Activity in Older Adults
This study is a randomized trial that will compare the effects of two, 12-week activity interventions on patterns of physical activity, physical health, and quality of life measures in 40 older adults who are able to walk for…
- Trial name
- RISE (NCT02146001)
- Testing
- Reducing sedentary behavior group, Moderate-to-vigorous activity group
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Exercise, Physical Activity
Companion: Sensor-based Two-way Communication for Physical Activity in Older Adults
This pilot study is a small sample (N=46) 16-week clinical trial with a follow-up after 24-weeks among sedentary adults >60 y with a BMI >25 kg/m2 to tests the impact of a hybrid artificial intelligence behavior change system…
- Trial name
- NCT04827212
- Testing
- Companion
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Movement Disorders, Aging
Effects of Exercise Poles on Older Adults During Exercise Walking
This study uses a patented type of exercise poles, developed to assist runners rehabilitating from lower body injuries. These poles may offer older adults improved stability, reduced fear of falling, and lessened lower body pain…
- Trial name
- NCT00037167
- Testing
- Exercise poles
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Older Adults (65 Years and Older), Hispanic Americans
Physical and Cognitive Aging Study in Older Adults
Hispanic Americans are the fastest growing older adult group in the United States, disproportionally increasing the risk of an Alzheimer's disease and related dementias diagnosis.
- Conditions
- Older Adults (65 Years and Older), Hispanic Americans, Cognitive Aging, Aging, Healthy
- Trial name
- PASOS (NCT06726616)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Florida
Frail Elderly
Multicomponent Exercise and Comprehensive Geriatric Assessment Program (FRAIL+AP) for Frail Older Adults in Primary Care
Frailty is a multidimensional clinical syndrome associated with increased vulnerability to adverse health outcomes in older adults.
- Trial name
- FRAIL+AP (NCT07643064)
- Testing
- FRAIL+AP Program, Usual Care
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Alberto Bermejo Franco
Geriatric Disorder, Sarcopenia
Feasibility and Benefits of Group Based Exercise in Residential Aged Care Adults
This study is a pilot study (feasibility and acceptability study), which will compare feasibility and efficacy outcomes between a 12-week Exercise Program and control group in RAC residents.
- Trial name
- NCT02640963
- Testing
- Exercise, Control
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Bond University
Osteoarthritis, Knee
Blood Flow Restriction Exercise Study
This pilot study will investigate the effects of blood flow restriction (BFR) exercise for up to 4-6 weeks prior to total knee arthroplasty (TKA) surgery in older patients to measure clinical outcomes such as strength, lower…
- Trial name
- BFR (NCT02868021)
- Testing
- Strength testing, Short Physical Performance Battery (SPPB), Six-minute walk (SMW)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Florida
Older Adults, Exercise
A Technology-based Exercise Program for Older Adults
This intervention aimed to collect relevant information for the development of a technology-based exercise application. This information-collection is based on the opinions of older adults (65+ years) as well as experts from the…
- Conditions
- Older Adults, Exercise, Mobile Application
- Trial name
- Work-Oud (NCT05650515)
- Testing
- Co-creation
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- PXL University College
Sleep Quality, Cognitive Function
Effects of Walking Exercise on Sleep Quality in Older Adults
This study aims to explore whether increasing physical activity can improve sleep quality in older adults, particularly those with poor sleep, and whether such improvements positively influence cognitive functions such as memory…
- Trial name
- NCT07027176
- Testing
- walking exercise
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yea-Ru Yang
Iron Deficiency
Improving Iron Levels in Female Endurance, Intermittent, and Power/Strength Athletes Aged 16-35
The goal of this clinical trial is to learn if different types and doses of oral iron supplements can improve iron levels, athletic performance, and gut health in young female athletes with low iron stores.
- Trial name
- FeSc2 (NCT06942208)
- Testing
- Low-dose iron (ferrous sulfate), Yeast-bound iron (ferrous sulfate), High-dose iron (ferrous sulfate)
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Obesity, Cardiovascular Risk Factor
The Pitt Retiree Study: A Diabetes Prevention Program for Medicare Eligible Older Adults
The Pitt Retiree Study (PRS) disseminates a novel, yet practical, diabetes prevention program among Medicare eligible adults in Western Pennsylvania.
- Conditions
- Obesity, Cardiovascular Risk Factor, Eating Behavior, Diet Modification
- Trial name
- PRS (NCT03192475)
- Testing
- GLB plus phone contacts, GLB plus newsletter contacts
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Older Adults, Muscle Protein Synthetic Response to Protein
Influence of Reduced Daily Step Count and Anabolic Interventions on Muscle Protein Metabolism in Older Persons
As the loss of muscle mass with aging is associated with a dysregulation of muscle protein synthesis (MPS) that is generally characterized by an 'anabolic resistance' to nutrients, the primary outcome of the trial is to…
- Conditions
- Older Adults, Muscle Protein Synthetic Response to Protein, Reduced Physical Activity
- Trial name
- NCT02347137
- Testing
- step-reduction, step-reduction plus resistance exercise
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McMaster University
Aging, Nutrition
Sustainable Insect-based Protein Supplement in the Elderly: a Pilot Study
This pilot randomized, double-blind, controlled trial evaluated the effects of a Tenebrio molitor-enriched protein biscuit combined with a structured physical activity program on cardiometabolic health in older adults.
- Conditions
- Aging, Nutrition, Sustainable Diets, Cardiometabolic Health
- Trial name
- SIPSE (NCT07456319)
- Testing
- INSECT - Protein suplement based on edible insect flour, Control
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitat Oberta de Catalunya
Middle Aged
A Text- and Audio-based Intervention to Promote Physical Activity in Midlife
This is a randomized, controlled pilot trial (N=30) to examine the feasibility, acceptability, and preliminary efficacy of the Move with Meaning program, an 8- week, text message- and audio-based intervention to promote physical…
- Trial name
- NCT06172933
- Testing
- Move with Meaning
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Knee Osteoarthritis
Mobility Optimization Through Velocity Exercise
Knee Osteoarthritis (OA) accounts for a significant proportion of mobility limitations and is one of the most disabling problems facing the growing population of older adults.
- Trial name
- MOVE (NCT00844558)
- Testing
- Gait Training, Control
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of Iowa
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