Clinical trials: Elderly Patients (>65 Years)
Diabetes Type 1
Transition of T1DM Patients Aged Over 65 Years Into AHCL (780G) Insulin Pump
Older people with diabetes have a higher risk for cognitive impairment and for physical disability whether this may be effected by an improvement in glucose indices is unknown.
- Trial name
- 780G65+ (NCT06207838)
- Testing
- MiniMed 780G system
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Jagiellonian University
Aged, Aged, 80 and Over
An Individualized Physical Activity Program in Patients Over 65 Years With Hematologic Malignancies
Older people with cancer differ from younger patients due to the combined effects of aging, comorbidities and cancer treatments on their health.
- Conditions
- Aged, Aged, 80 and Over, Leukemia, Myeloid, Acute, Lymphoma, Non-Hodgkin
- Trial name
- OCAPI (NCT04052126)
- Testing
- Individualized physical activity program
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Centre Leon Berard
Malnutrition
Acceptability Study of Nutritional Supplements in Hospitalized Elderly Patients
Malnutrition is a major health problem with serious consequences for the quality of life of elderly people: it increases the number of hospitalizations and lengths of stay, worsens functional dependency and increases morbidity…
- Trial name
- CNO Evaluation (NCT02810470)
- Testing
- Fortimel Compact Protein, Fortimel Cream
- Volunteers
- 107 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Rheumatoid Arthritis
Prospective Study of Patients With Rheumatoid Arthritis After the Age of 65
Rheumatoid arthritis (RA) is associated with a higher prevalence of infections, malignancies, osteoporotic fractures and cardiovascular diseases.
- Trial name
- PRESAGE (NCT02686320)
- Where
- France
- Volunteers
- 176 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fraility, COPD (Chronic Obstructive Pulmonary Disease)
Respiratory Exercises in Frail Elderly COPD Patients
Purpose: This study evaluated the impact of a structured intervention on frailty, lung function, physical capacity, and dyspnea in elderly COPD patients.
- Conditions
- Fraility, COPD (Chronic Obstructive Pulmonary Disease), Older Adults (65 Years and Older)
- Trial name
- NCT07472530
- Testing
- breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Aggressive Non-Hodgkin Lymphoma
Metronomic Chemotherapy in Elderly Non-fit Patients With Aggressive B-Cell Lymphomas
This is a phase II study of metronomic chemotherapy in elderly non-fit patients (>65 years) with aggressive B-Cell lymphomas
- Trial name
- NCT03161054
- Testing
- Prednisone, Vinorelbine, Etoposide
- Where
- 10 sites in Italy
- Volunteers
- 21 people
- Sponsor
- Fondazione Italiana Linfomi - ETS
Primary Hyperparathyroidism
Surgery for Primary Hyperparathyroidism (pHPT) in Patients Older Than 65 Years Compared With Follow-up
General consensus and contemporary guidelines, recommend surgery for primary hyperparathyroidism (pHPT)for all patients below the age of 50, for patients with pronounced hypercalcemia and for patients with organ complications to…
- Trial name
- NCT01087619
- Testing
- Parathyroid surgery
- Where
- Sweden
- Volunteers
- 102 people
- Sponsor
- Region Skane
Older Adults (65 Years and Older)
Quantifying the Attentive Behaviors of Older Adults During Over-the-counter Drug Selection
Per-capita consumption of medication is higher in older adults than any other sector of the population. In fact, it has been estimated that although older adults comprise 13% of the population they take 34% of all prescriptions…
- Trial name
- NCT02188134
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Vasculitis, Wegener's Granulomatosis
Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years
The aim of this trial is to lower the morbidity rate in elderly patients affected with systemic necrotizing vasculitides, by reducing mortality and improving global outcome.
- Conditions
- Vasculitis, Wegener's Granulomatosis, Microscopic Polyangiitis, Churg-Strauss Syndrome
- Trial name
- CORTAGE (NCT00307671)
- Testing
- prednisone, methylprednisolone,cyclophosphamides, Cyclophosphamide, Azathioprine,prednisone,methylprednisolone, Mycophenolate mofetil,methotrexate
- Where
- France
- Volunteers
- 108 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Metastatic Breast Cancer
Prospective Observational Study in Patients With Metastatic Breast Cancer Treated With Anthracyclines
This is an open, multicentre, prospective observational (non-interventional) study, performed in Belgium. Principal objectives: 1.
- Trial name
- NCT01555944
- Where
- 24 sites in Belgium
- Volunteers
- 60 people
- Sponsor
- Teva Pharma
Hemodynamic Instability
Hemodynamic Effects of Continuous Spinal Anesthesia in Patient Aged Over 65 Years
Compared to single-dose spinal anesthesia, continuous spinal anesthesia using small titrated doses of local anesthetic, was safe, efficient and provided better hemodynamic profile in elderly patients.
- Trial name
- NCT03195166
- Testing
- FloTrac sensor/Vigileo
- Where
- Tunisia
- Volunteers
- 20 people
- Sponsor
- University Tunis El Manar
Relapsed Follicular Lymphoma
A Phase III Multicenter, Randomized Study Comparing RIT Vs ASCT in Patients With Relapsed/Refractory (FL)
This is a Phase III, multicenter, open-label, randomized and controlled study to compare the efficacy of a consolidation therapy with RIT versus ASCT in patients with FL in CR or PR after second or third line chemotherapy…
- Trial name
- NCT01827605
- Testing
- ZEVALIN, BEAM
- Where
- 38 sites in Italy
- Volunteers
- 159 people
- Sponsor
- Fondazione Italiana Linfomi - ETS
Sever Aplastic Anaemia, Elderly (People Aged 65 or More)
Dose-attenuated IST and Hetrombopag in Elderly (≥65 Years) Patients With Severe Aplastic Anemia
This is a prospetive,Single-Center, Single-Arm, Phase IIB Clinical Study.This study aims to evaluate the efficacy and safety of dose-attenuated IST combined with Hetrombopag in elderly patients (≥65 years) with VSAA/SAA.
- Conditions
- Sever Aplastic Anaemia, Elderly (People Aged 65 or More), Immunosuppressive Treatment
- Trial name
- NCT07010237
- Testing
- Dose-attenuated IST and Hetrombopag
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Aged, Patient Admission
Impact of Collaborative Pharmaceutical Care on Hospital Admission Drug Prescriptions for Patients 65 Years of Age and Older
The primary objective of this study is to evaluate the impact of the implementation of collaborative pharmaceutical care on drug support at admission for patients 65 years of age and older.
- Conditions
- Aged, Patient Admission, Hospitalization
- Trial name
- MEDREV (NCT02598115)
- Testing
- Collaborative Pharmaceutical Care
- Where
- 6 sites in France
- Volunteers
- 622 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Obesity, Morbid, Surgery
Sleeve Versus Bypass in Older Patients: a Randomized Controlled Trial
The aim of the study is to compare two different bariatric procedures performed in patients with 65 years or more: gastric bypass and sleeve gastrectomy.
- Conditions
- Obesity, Morbid, Surgery, Elderly
- Trial name
- BaSE (NCT03339791)
- Testing
- Sleeve Gastrectomy, Gastric Bypass
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- University of Sao Paulo General Hospital
Loneliness
Compartiendo Salud: Community-Based Intervention for Loneliness
Unwanted loneliness is the gap between the social relations a person has and those they want. The main objective of this research is to assess the impact of a multidimensional community-based intervention on the feeling of…
- Trial name
- SoledadLP (NCT06829758)
- Testing
- Compartiendo Salud
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Servicio Canario de Salud
Metastatic Melanoma
Tolerance of Targeted Therapy Used in Metastatic Melanoma in Patients Aged Over 65 and 75-year-old
Since 2013, therapeutic care of metastatic melanoma (MM) has greatly improved, especially thanks to BRAF and MEK targeted therapies.
- Trial name
- TOLBRIPA (NCT03155217)
- Where
- France
- Volunteers
- 358 people
- Sponsor
- University Hospital, Montpellier
Acute Myeloid Leukemia
Treatment of Older Adult Acute Myeloid Leukemia Patients Aged 55 to 65 Years
The purpose of this study is to determine whether the escalation dosage of Daunorubicin and cytarabine is effective and safety in the treatment of older adult Chinese acute myeloid leukemia（AML） patients aged 55 to 65 years.
- Trial name
- NCT02432872
- Testing
- Daunorubicin, Cytarabine
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Jianxiang Wang
Non-squamous Non-small Cell Lung Cancer
Efficacy Study of Avastin® With Pemetrexed +/- Carboplatin to Treat Elderly Patients With Non-small Cell Lung Cancer
Multi-center, open, randomized (parallel) and comparative phase III. Eligible patients will receive bevacizumab + chemotherapy for a minimum of 4 cycles followed by bevacizumab (+ pemetrexed, if appropriate) maintenance therapy…
- Trial name
- 65plus (NCT00976456)
- Testing
- Bevacizumab + Pemetrexed, Bevacizumab + Pemetrexed + Carboplatin
- Where
- Germany
- Volunteers
- 271 people
- Sponsor
- PD Dr. med. Wolfgang Schuette
Hip Osteoarthritis, Hip Pain Chronic
PENG Block Variants With Dexamethasone and Dexmedetomidine in Older Adults
This study will compare three different versions of the Pericapsular Nerve Group (PENG) block in adults aged 65 years and older who are undergoing surgery for hip conditions.
- Trial name
- NCT07327931
- Testing
- Dexamethasone (intravenous), Dexamethasone (intravenous) with Dexmedetomidine (perineural), Dexamethasone (perineural) with Dexmedetomidine (perineural)
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Poznan University of Medical Sciences