Clinical trials: Elderly People
Elderly (People Aged 65 or More), Neurocognition
Assessment of Informal Support Provided by Caregivers at Different Stages of Alzheimer's Disease
In France, approximately 1,200,000 people aged 65 and over suffer from Alzheimer's disease or related disorders, of which Alzheimer's disease (AD) accounts for 70% of cases. This prevalence could double by 2050.
- Conditions
- Elderly (People Aged 65 or More), Neurocognition, Alzheimer s Disease
- Trial name
- ICAD (NCT07409506)
- Testing
- " Ressources Utilisation in Dementia " (RUD) questionnaire.
- Where
- France
- Volunteers
- 312 people
- Sponsor
- Hospices Civils de Lyon
Frail Elderly Syndrome
Protocols and Guidelines for the Use of Digital Twins in Frail Older People
The Proto-Aging study aims to define experimental protocols and guidelines to enable the development of musculoskeletal models (digital twins) of elderly people, with the ultimate goal to comprehensively characterize frail elders…
- Trial name
- Proto-Aging (NCT05854316)
- Testing
- Comprehensive Biomechanical assessment
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Aged
The Foot Posture and Falling Risk in Older People
This research will be conducted to examine the relationship between the foot postures and fall risks of elderly individuals living in nursing homes, to identify the factors that most affect the risk of falling, and to inform…
- Trial name
- NCT06153732
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Bahar Anaforoglu Külünkoglu
Coronary Arteriosclerosis, Endothelial Dysfunction
Effect of Aged Garlic Extract (AGE) on Improving Coronary Atherosclerosis in People With Type 2 Diabetes Mellitus
The purpose of this research study is to see the effect of taking Aged Garlic Extract (AGE) on the progression of coronary plaque, a condition called atherosclerosis, in people diagnosed with Diabetes.
- Conditions
- Coronary Arteriosclerosis, Endothelial Dysfunction, Type 2 Diabetes Mellitus
- Trial name
- NCT03931434
- Testing
- Aged Garlic Extract (AGE)
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Infection, Bacterial
Effect of a Infection Control Program on the Reduction of Bacterial Contamination on NG Tube Feeding in RCHEs
Septicaemia is a potential complication of nasogastric (NG) tube feeding contamination (Leanne, 2014; Anderton, 2000) and a major cause of morbidity and mortality in residential care home for elders ( RCHEs) (Leanne, 2014).
- Trial name
- NCT04075344
- Testing
- Multimodal Infection control programme
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Enteral Nutrition
Assessment of the Effects of Probiotic Supplementation on Gut Microbiota Composition and Short-chain Fatty Acid Production in Frail Elderly Patients Receiving Home Enteral Nutrition With an Oligomeric Formula.
This is an investigator-initiated, spontaneous, non-profit, randomized intervention study with two parallel arms. The study aims to evaluate the effect of a 30-days probiotic supplementation on the composition of the intestinal…
- Trial name
- MICROBIOTA (NCT07437352)
- Testing
- probiotic supplementation
- Where
- Italy
- Volunteers
- 27 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Gastrointestinal Dysfunction
The Effect of Probiotic Supported Yogurt Consumption on Gastrointestinal Symptoms
Probiotics have beneficial effect on Gastrointestinal Symptoms. The aim of this study is to determine the effect of probiotic yogurt consumptions on the people who have gastrointestinal symptoms mainly constipation.
- Trial name
- NCT05566171
- Testing
- Activia Probiotic Yogurt
- Where
- Cyprus
- Sponsor
- Eastern Mediterranean University
Osteoporosis, Cognitive Decline
Vitamin B12 and Folic Acid Supplementation for Preventing Fractures in Elderly People
It is hypothesized that vitamin B12 and folic acid supplementation reduces the number of incident fractures. The proposed study, a randomized placebo-controlled intervention trial, compares daily supplementation with folic acid…
- Trial name
- B-PROOF (NCT00696514)
- Testing
- Vitamin B12, folic acid, Vitamin D3
- Where
- 3 sites in Netherlands
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Aged 65 Years or Older, Community Dwelling Older Adults
Validating a Multifactorial Algorithm to Predict Fall Risk in Community Dwelling Older Persons Aged 65 Years or Older
Falls in older adults have an annual incidence between 23 and 34% for persons of 65 years and older. The lack of transfer of promising research results on falls prevention to daily practice may have several explanations.
- Conditions
- Aged 65 Years or Older, Community Dwelling Older Adults, Falls Risk, Falls (Accidents) in Old Age
- Trial name
- NCT06961799
- Testing
- Multifactorial algorithm to predict fall risk
- Where
- Belgium
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- University Ghent
COVID-19
Geriatric COVID-19 Serology
Coronaviruses are important human and animal pathogens. At the end of 2019, a new coronavirus was identified as the cause of a cluster of pneumonia cases in Wuhan, a city in China's Hubei province.
- Trial name
- SeroGerCov (NCT05109546)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Quadrivalent Influenza Virus Vaccine
Safety Study of Quadrivalent Influenza Virus Vaccine in Healthy People Aged 3 Years and Older
This study evaluates the safety of Quadrivalent Influenza Virus Vaccine in Healthy People Aged years 3 to 60.40 Subjects will be equally divided into 2 groups,including 3-17 years old and 18-60 years old.Adult group first receive…
- Trial name
- NCT02708173
- Testing
- One dose of Quadrivalent Influenza Virus Vaccine
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beijing Chaoyang District Centre for Disease Control and Prevention
Tuberculosis
Phase IIb Clinical Study of Recombinant Mycobacterium Tuberculosis Allergen ESAT6-CFP10 on Healthy People Aged 18-65
The investigators select 500 subjects who meet the standard and are considered as study population I. Do specific gamma-interferon detection before the skin test， then inject intradermally with two dosage ESAT6-CFP10 and…
- Trial name
- IIb-healthy (NCT02389322)
- Testing
- 5μg/ml ESAT6-CFP10, 10μg/ml ESAT6-CFP10, BCG
- Where
- China
- Volunteers
- 1,044 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Elderly (People Aged 65 or More)
Relationship Between Cervical Pain According to Cervical Proprioceptive Awareness Level in the Healthy Elderly
Aging is a progressive and irreversible process characterized by changes occurring at the cellular level, in organs and systems.
- Trial name
- NCT07238595
- Testing
- Cervical Joint Position Error Test (CJPE)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
LLM-based AI Dialogue Bot, Depression
Young People Aged 18-25 With Depression or Anxiety Mood Participate in an LLM-based Digital Dialogue Intervention Study
This study is a 28-day randomized controlled trial (RCT). Residents were randomly assigned to an intervention group or a waiting group according to the order in which they were successfully contacted by the staff, and each user…
- Conditions
- LLM-based AI Dialogue Bot, Depression, Anxiety
- Trial name
- NCT06346496
- Testing
- Douyin Xinqing AI dialog bot, Douyin Xinqing AI dialog bot for delayed intervention
- Where
- China
- Volunteers
- 657 people, healthy volunteers welcome
- Sponsor
- Institute of Psychology, Chinese Academy of Sciences
Atrial Fibrillation
Effectiveness of Patch-Electrocardiogram Recorders in Screening for Atrial Fibrillation in Elderly People in the Chinese Community
This prospective, multicenter, single-arm study evaluates the effectiveness of a single-lead patch electrocardiogram (ECG) recorder in screening for atrial fibrillation (AF) among community-dwelling elderly individuals aged ≥60…
- Trial name
- NCT07627672
- Testing
- Single-lead patch ECG recorder
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Beijing Anzhen Hospital
Healthy Elder People
Feasibility Clinical Study of NLA Tool
The study is to evaluate the feasibility of the NLA tool, a combined assessment of nutritional and physical functional status, to provide personalized advice for the independence and mobility of elderly.
- Trial name
- NCT01985282
- Testing
- Nutrition Status Questionnaires and Physicial Function Test
- Where
- Japan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
COVID-19
Omicron BA.4/5-Delta COVID-19 Vaccine Phase I Clinical Trial
The purpose of this study is to evaluate the safety of Omicron BA.4/5-Delta strain recombinant novel coronavirus protein vaccine (CHO cells) after vaccination in people aged 18 and over.
- Trial name
- NCT06043388
- Testing
- Omicron BA.4/5-Delta strain recombinant novel coronavirus protein vaccine (CHO cells)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Older Women, Older Adults, Balance
Line Dancing With Blood Flow Restriction for Balance and Gait of Older Women (In-Person vs Online)
Falls are a leading cause of injury-related hospitalization among older women. Age-related declines in gait speed and postural stability are known risk-factors for falls.
- Conditions
- Older Women, Older Adults, Balance, Older Adults, Healthy Older Adults in the Community
- Trial name
- NCT07860541
- Testing
- Wearing blood flow restriction, Online dance classes, In-person dance classes
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Concordia University, Montreal
Diabetes Mellitus, Type 2, Sense of Coherence
BEYO Project to Promote Sense of Coherence and Self-care of Elderly People With Type 2 Diabetes
1. Objectives of the Project The BEYO project is designed based on the middle range theory of self-care of chronic illness and salutogenic theory.
- Conditions
- Diabetes Mellitus, Type 2, Sense of Coherence, Self Care, Strengths-based Intervention
- Trial name
- BEYO (NCT03237975)
- Testing
- Be the Expert for Your Own (BEYO), Routine health education
- Where
- 2 sites in China
- Volunteers
- 132 people
- Sponsor
- Chinese University of Hong Kong
Type 1 Diabetes Mellitus
The Diabetes Transition Study for Young People Aged Between 16-20 Years of Age.
Study into the use of a diabetes specialist transition nurse in the care of young people aged 16-20 years, with type 1 diabetes; undergoing transition from the paediatric to the adult diabetes services at the Northampton General…
- Trial name
- NCT04754919
- Testing
- Transition intervention group, Post transition group
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northampton General Hospital NHS Trust