Clinical trials: Elderly Persons
Diabetes Mellitus Type 2, Impaired Balance in Elderly
Improvement Through Movement - Balance Control and Somatosensory Function in People With Diabetes Mellitus Type 2
This study focuses on improving balance control and somatosensory functions in individuals aged 60 years and older with diabetes mellitus tyoe 2 (DMT2).
- Conditions
- Diabetes Mellitus Type 2, Impaired Balance in Elderly, Somatosensory Disorders, Balance Control in Elderly
- Trial name
- NCT07786194
- Testing
- Balance control and exercise training, Relaxation and exercise training
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Universiteit Antwerpen
Older People
The Effect of Exercise on Cognitive Status in Older Adults
The purpose of the study is to demonstrate the effectiveness of the different combinations of exercises on the cognitive status of older adults with cognitive decline.
- Trial name
- NCT05532371
- Testing
- Aerobic exercise training combined with lower limb strengthening, Dual-task training combined with lower limb strengthening group (DG), Aerobic exercise training combined with dual-task training and lower limb strengthening
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Muğla Sıtkı Koçman University
Type 1 Diabetes
COVID-19 Pandemic Lockdown Effect in Adolescents and Young Adults With Type 1 Diabetes: Positive Results of an Unpreceded Challenge for Telemedicine and Patient Self-management
Lockdown resulting from the COVID-19 pandemic was an unpreceded model of the impact of lifestyle on chronic diseases, especially for adolescents and young adults with type 1 diabetes (T1D) whose lifestyle is known to strongly…
- Trial name
- COVIDIABADO (NCT04669912)
- Testing
- glucose control and sensor usage
- Where
- France
- Volunteers
- 77 people
- Sponsor
- Centre Hospitalier Sud Francilien
Sedation, ED95
the 95% Effective Dose of Ciprofol for Adjunctive Sedation Undergoing Knee Arthroplasty in Elderly People
Regional anesthesia is a common clinical anesthesia method, and regional anesthesia-assisted sedation play a central role in promoting patient comfort and relieving anxiety.
- Conditions
- Sedation, ED95, Knee Arthroplasty
- Trial name
- NCT06293144
- Testing
- Ciprofol
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Second Hospital of Shanxi Medical University
Atrial Fibrillation, Thrombus Due to Heart Valve Prosthesis
Validation of International Warfarin Pharmacogenetics Consortium (IWPC) Algorithm in Elderly Patients With Comorbidity
The purpose of this study is to validate the International Warfarin Pharmacogenetics Consortium (IWPC) algorithm in a prospective cohort of elderly people (65 years or older) with heart valves and/or nonvalvular atrial…
- Trial name
- VIALE (NCT02069132)
- Testing
- Warfarin
- Where
- 3 sites in Italy
- Volunteers
- 376 people
- Sponsor
- University of Campania Luigi Vanvitelli
Fragility, Sarcopenia
Efficacy of an Intervention to Prevent Frailty in Obese Elderly People (PRE-FROB)
Rationale: There is increasing evidence that obesity may be a risk factor for frailty in the elderly. Obesity favors a state of chronic inflammation and insulin resistance, involves a fatty infiltration of the muscle and an…
- Conditions
- Fragility, Sarcopenia, Obese, Elderly
- Trial name
- PRE-FROB (NCT03000907)
- Testing
- Intervention
- Where
- Spain
- Volunteers
- 319 people
- Sponsor
- Consorci Sanitari del Maresme
Mild Cognitive Impairment, Mild Dementia
Computer-based Cognitive Rehabilitation Program for Healthy Older Adults, Older People With Mild Cognitive Impairment and Mild Dementia
This study will adopt a newly developed computer-based cognitive rehabilitation program targeting the encoding stage of memory. The aims of the study are: 1.
- Conditions
- Mild Cognitive Impairment, Mild Dementia, Healthy Older Adults
- Trial name
- NCT03430401
- Testing
- Perceptual-based memory encoding, Semantic-based memory encoding, Cognitive stimulation
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Western Sydney
HPV Infection, HPV-Related Carcinoma
A Phase I Clinical Trial to Evaluate the Safety of 15-valent HPV Vaccine in Healthy Chinese People Aged 18-45 Years
To evaluate the safety and tolerability of 15-valent HPV vaccine in 9-45year-old participants.
- Conditions
- HPV Infection, HPV-Related Carcinoma, Genital Wart, HPV-Related Intraepithelial Neoplasia
- Trial name
- NCT06454175
- Testing
- 15-valent recombinant human papillomavirus vaccine (Hansenulapolymorpha)
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shanghai Bovax Biotechnology Co., Ltd.
HIV Infections, Alcohol Drinking
Precision Microbiota Interventions for Senoreduction Trial
People with HIV who drink alcohol are at increased risk for accelerated aging biology, including increased immune senescence. This randomized, double-blind, crossover clinical trial evaluates two generally recognized as safe…
- Conditions
- HIV Infections, Alcohol Drinking, Aging, Immunosenescence
- Trial name
- PreMIS (NCT07462767)
- Testing
- Limosilactobacillus reuteri, Blueberry extract
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Cervical Cancer
Concurrent Chemoradiotherapy for Cervical Cancer in Elderly Women
The purpose of this study is to evaluate the efficiency and safety of weekly Cisplatin /Liposome paclitaxel concurrent chemoradiothrapy in the treatment of locally advanced cervical cancer in elderly women.
- Trial name
- NCT01594099
- Testing
- irradiation, Cisplatin, liposome paclitaxel
- Volunteers
- 45 people
- Sponsor
- Xi'an Jiaotong University
Human Papillomavirus Infection, HPV
Human Papillomavirus in Young People Epidemiological Research 4
Anal cancer is overrepresented among gay, bisexual and other men who have sex with men (MSM), particularly those living with HIV.
- Conditions
- Human Papillomavirus Infection, HPV, HPV Infection, Anal Cancer
- Trial name
- HYPER4 (NCT05587738)
- Where
- Australia
- Volunteers
- 500 people
- Sponsor
- Monash University
Neoplasms, Frailty
Ready for Safe Cancer Treatment (RESET): A Comprehensive Perioperative Program for Surgical Oncology
The goal of this randomized controlled clinical trial is to evaluate whether the Ready for Safe Cancer Treatment (RESET) program improves perioperative care and supports safe hospital discharge in two surgical populations: adult…
- Conditions
- Neoplasms, Frailty, Surgical Procedures, Operative
- Trial name
- RESET (NCT07727876)
- Testing
- RESET multimodal perioperative care pathway, Standard perioperative care
- Where
- 2 sites in Poland
- Volunteers
- 12,800 people
- Sponsor
- Regional Specialist Hospital in Wroclaw
Falls, Balance Assessment
Developing a Daily-use Fall Risk Assessment Device in Clinical Setting
Study Objectives Objective 1: Compare the fall risk assessment results between balance sensors, traditional tests, and clinical diagnoses.
- Trial name
- NCT06767163
- Testing
- iBalance
- Where
- Hong Kong
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Dysfunction of Vestibular System
Effectiveness of Computer Assisted Training for Older People With Vestibular Dysfunction
BACKGROUND A Cochrane review from 2003 found that about 30% of people 65 years or older each year fall and that number is even higher for elder people living in institutions.
- Trial name
- NCT01344408
- Testing
- Computer-training
- Where
- Denmark
- Volunteers
- 63 people
- Sponsor
- University of Aarhus
Accidental Falls, Elderly
Evaluation of a Fall Detection Device in Isolated Elderly
The objective of this study is to evaluate the evolution 6 months after a fall occurring at home in people over 75 equipped or non-equipped with a precocious detection device.
- Trial name
- VIGI91 (NCT01422252)
- Testing
- Vigi'Fall®
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dynapenia, Abdominal Obesity
Effectiveness of Whole Body Vibration on Health Outcomes in Older Adults With Dynapenic Abdominal Obesity
This study focuses on whole body vibration training (WBVT), a form of neuromuscular training that uses mechanical vibrations. WBVT has been shown to improve muscle function, bone mineral density, and quality of life.
- Trial name
- NCT07180485
- Testing
- whole body vibration training, control group
- Volunteers
- 120 people
- Sponsor
- Dalin Tzu Chi General Hospital
Aging
Growth Hormone Evaluation in the Elderly People
The aim of this study is to evaluate the growth hormone (GH) and adrenocorticotrophic hormone (ACTH) secretion in elderly without hypothalamic-pituitary disease using the glucagon stimulation test (using Glucagen® Hypokit, Novo…
- Trial name
- NCT02240043
- Testing
- growth hormone secretion
- Volunteers
- 48 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Polypharmacy, Frail Elderly Syndrome
Discontinuation of Long-term Medications in Older People Entering Nursing Home Care
Older people often have several chronic diseases requiring several medications all at once. Taking several medications all at once is called polypharmacy. Polypharmacy is common in nursing home residents.
- Conditions
- Polypharmacy, Frail Elderly Syndrome, Inappropriate Prescribing, Drug-Related Side Effects and Adverse Reactions
- Trial name
- STOPPFrail (NCT03501108)
- Testing
- STOPPFrail deprescribing criteria
- Where
- Ireland
- Volunteers
- 160 people
- Sponsor
- University College Cork
Exercise, Long Term Care Facilities
Partnered Multicomponent Exercise for Elderly in Long-term Care Facilities
This study aimed to explore the effects of a partnered multicomponent exercise program on improving the physical function and sense of well-being of elderly people in Long-term Care Facilities (LTCFs).
- Conditions
- Exercise, Long Term Care Facilities, Physical Function, Happiness
- Trial name
- NCT05021848
- Testing
- partnered multicomponent exercises program
- Where
- Taiwan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Healthy Adult Participants
Alcohol Sensitivity Among Older Adults Who Consume Alcohol
This is a proof-of-concept study exploring individual differences in sensitivity to alcohol among older healthy current drinkers aged 65 to 80.
- Trial name
- NCT07636447
- Testing
- Alcohol (Oral)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Florida
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