Clinical trials: Elderly Persons
Old Person
Evaluate the Link Between the Characteristics of Oral Physiology and the Formation of the Food Bolus During the Consumption of Dairy Products in Elderly People
The aim of this study is to understand how dairy products enriched in minerals and proteins are broken down in the mouth. More specifically, investigators wish to evaluate the link between oral physiology (salivation and…
- Trial name
- AlimaSSenSLait (NCT03227913)
- Testing
- Two samples of saliva, Chewing behaviour, Study of the food bolus
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Critical Illness
Predictive Model for Mortality in Older People With Critical Illness
The present study aims to develop a predictive model to identify elderly patients with the highest likelihood of mortality upon admission to an intensive care unit.
- Trial name
- VITA (NCT06727903)
- Testing
- laboratory biomarker analysis
- Where
- 14 sites in Spain
- Volunteers
- 450 people
- Sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf
Polypharmacy, Cholinergic Antagonists
DBI - Tool for Medication Reviews in Older People
Older people often use medications with anticholinergic or sedative side effects which increase the risk of falling, fractures caused by falls and cognitive impairment.
- Trial name
- NCT02317666
- Testing
- Medication Review
- Where
- Netherlands
- Volunteers
- 157 people
- Sponsor
- University of Groningen
Lymphopenia, Covid19
Study of Lymphopenia as a Specific Biomarker or Prognostic Risk Factor for Disease Severity in Elderly Patients With COVID-19
Background: Lymphopenia is reported to be associated with the severity of disease progression in COVID-19. Low lymphocyte count is also associated with increasing age.
- Conditions
- Lymphopenia, Covid19, Older People
- Trial name
- NCT04800731
- Testing
- observation no intervention
- Where
- Belgium
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Elderly Persons
Biological MArkers of FRAilty in Elderly Subjects
Epidemiological data from Europe have shown that around 30% of subjects aged over 65 years of age are pre-frail, and 15% are frail.
- Trial name
- MAFRA (NCT02816580)
- Testing
- Blood collection
- Where
- France
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Fraility, Risk of Falling
Physical Activity Monitoring in Frailty and Falling
BioSensics has developed a Physical Activity Monitoring System (PAMSys) that consists of a single wearable motion sensor that is worn on the torso.
- Trial name
- NCT01880229
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- BioSensics
Postoperative Delirium
Study of Postoperative Delirium in Elderly People After Orthopedic Surgery
The purpose of this study is to investigate the possible relationship of microRNA and postoperative delirium.
- Trial name
- NCT02817386
- Testing
- interview
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zhongnan Hospital
Elderly
Biological & Fonctional Signatures for Muscle Failures, Aged People & Personalized Physical Activity
Physical activity is one of the most effective therapeutic interventions for frailty, sarcopenia or dynapenia. The benefits of physical activity processes are already widely documented.
- Trial name
- BioFaSt (NCT05343286)
- Testing
- blood sample, physical assessement, psychometric assessment
- Where
- France
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Activity
Effects of Fun Physical Activity on the Interest to Daily Physical Activity and Sarcopenia of Elderly People
In this research, the elderly living in nursing homes were selected in two group control and intervention. Intervention group 3 times a week for 20 minutes during 2 months, fun physical exercises (including activities carried out…
- Trial name
- NCT02259673
- Testing
- Fun exercise
- Where
- Iran
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Insomia Disorder
A Trial to See if Daridorexant Can Help Adults and Elderly People With Insomnia Sleep Better During the Night and Function Better During the Day
The purpose of this clinical trial is to collect more data about the effect of daridorexant in adults and elderly people with insomnia disorder.
- Trial name
- DARI-DREAM (NCT07843329)
- Testing
- Daridorexant
- Volunteers
- 344 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Age-related Cognitive Decline
A Group Study on the Effects of a Short Multi-Domain Cognitive Training in Healthy Elderly Italian People
Alongside physiological cognitive ageing, nowadays there is an alarming increase in the incidence of dementia that requires communities to invest in its prevention.
- Trial name
- NCT03771131
- Testing
- Multi-domain cognitive training
- Where
- Italy
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Atrial Fibrillation, Atrial Flutter
A Study to Determine if Identification of Undiagnosed Atrial Fibrillation in People at Least 70 Years of Age Reduces the Risk of Stroke
The purpose of this study is to determine if an AF detection intervention in men and women at least 70 years of age with undiagnosed atrial fibrillation (AF) or atrial flutter (AFL) reduces the person-years incidence rate of…
- Trial name
- GUARD-AF (NCT04126486)
- Testing
- Zio®XT Monitor
- Where
- 176 sites in United States
- Volunteers
- 11,931 people
- Sponsor
- Bristol-Myers Squibb
Food Allergy in Children
CBT Group Intervention for Children With Food Allergy and Anxiety
The research will design and evaluate a CBT based intervention to support children aged 11-17 with food allergies. The research on this population has shown that they can experience high levels of anxiety in management of their…
- Trial name
- NCT04770727
- Testing
- CBT workshop
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Hypertension, Old Age
Study on Blood Pressure Variability and Frailty in the Older People
Observational prospective single-center, non-profit study. Primary objective of the study: To determine if the hypotensive phenotype, defined as one episode of daytime systolic blood pressure (SBP) <90 mmHg (or two episodes of…
- Trial name
- HypoPHrail (NCT06868069)
- Testing
- Diagnostic tests and questionnaires
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- Istituto Auxologico Italiano
Undernutrition
Supplementation With Nutrients Modulating IGF-1 and Cytokines in Elderly People at Risk of Undernutrition
The purpose of this study was to determine the improvement in nutritional status, especially in the level of insulin-like growth factor-1 (IGF-1) and its relationship with changes in the circulating cytokine levels, after…
- Trial name
- NCT02656186
- Testing
- Pre-intervention, Liquid nutritional supplement
- Volunteers
- 60 people
- Sponsor
- Yonsei University
Influenza
Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Influenza Vaccine, Fluarix®/Influsplit SSW® (2013/2014 Season), in Adults 18 Years of Age and Older
The purpose of this study is to assess, in adults 18 years of age and above, the immunogenicity and reactogenicity of the seasonal influenza vaccine, Fluarix/Influsplit SSW 2013/2014, containing the three vaccine influenza…
- Trial name
- NCT01884519
- Testing
- Fluarix/Influsplit SSW® (2013-2014 season)
- Where
- 4 sites in Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Elderly People
Improving the Quality of Life of Elderly Individuals Living in Nursing Homes
The development of physical activity (PA) and exercise habits improves strength, flexibility, balance and coordination, activities such as walking, sleep quality and cognitive status in elderly people and supports their…
- Trial name
- NCT06520956
- Testing
- Video based exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul Galata University
Knee Osteoarthritis, Physical Performance Parameters
Knee Osteoarthritis in Elderly People - Gait Analysis
The investigators perform a prospective controlled study and assess gait parameters in bilateral knee osteoarthritis (KOA) elderly patients with wireless system - BTS G-WALK, pre- and post-rehabilitation program.
- Conditions
- Knee Osteoarthritis, Physical Performance Parameters, Ultrasound, Quality of Life (QOL)
- Trial name
- NCT07093229
- Testing
- Ultrasound exam of quadriceps muscles (left/right) and gait analysis, Electrotherapy measures: transcutaneous nerve stimulation, ultrasound and low intensity laser; each one daily , applied on both lower limbs, for 10 days. Kinetic measures daily, Gait training
- Where
- Romania
- Volunteers
- 120 people
- Sponsor
- Diana Kamal
Type 1 Diabetes Mellitus
The Diabetes Transition Study for Young People Aged Between 16-20 Years of Age.
Study into the use of a diabetes specialist transition nurse in the care of young people aged 16-20 years, with type 1 diabetes; undergoing transition from the paediatric to the adult diabetes services at the Northampton General…
- Trial name
- NCT04754919
- Testing
- Transition intervention group, Post transition group
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northampton General Hospital NHS Trust
Diabetes, Older Diabetic Persons Without Dementia
CCT for Older Diabetic Adults
The current study examines the efficiency of a home-based computerized cognitive training (CT) intervention targeting older adults with diabetes.The primary aim of the study is to evaluate the effects of CCT on cognitive and…
- Trial name
- NCT02709629
- Testing
- Individualized and adaptive computerized cognitive training, Active control
- Where
- Israel
- Volunteers
- 85 people
- Sponsor
- Sheba Medical Center
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