Clinical trials: Elderly Persons
Diabetes Mellitus Type 2
Effect of Continuous Glucose Monitoring System on Glycemic Control in Non-insulin-Treated Elderly People With Type 2 Diabetes
The goal of this clinical trial is to learn if continuous glucose monitoring system works to improve glucose control in non-insulin-treated older adults with type 2 diabetes.
- Trial name
- INTELLECT (NCT07007676)
- Testing
- real-time CGM
- Where
- 21 sites in China
- Volunteers
- 148 people
- Sponsor
- Shanghai 6th People's Hospital
Humoral and Cellular Immune Responses
Cellular and Humoral Immunity in Elderly After Immunization With a Japanese Encephalitis Vaccine
The aim of this project is to investigate humoral and cellular immune responses before and after immunisation with the Japanese encephalitis vaccine IXIARO in subjects above 60 years of age and 18-40 years old subjects.
- Trial name
- NCT01398540
- Testing
- IXIARO
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Transurethral Resection of Prostate Syndrome, Elderly (People Aged 65 or More)
Hemoglobin-to-red Blood Cell Distribution Width Ratio and Hypothermia for Elderly Patient
As individuals age, they often enter a phase of increased "frailty." Elderly and frail patients represent a population that requires heightened sensitivity and close monitoring during surgical procedures.
- Conditions
- Transurethral Resection of Prostate Syndrome, Elderly (People Aged 65 or More), General Anesthetic
- Trial name
- NCT06790017
- Testing
- body temperature
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Knee Osteoarthritis
Impact of Physical Activity and Vitamin D on Osteoarthritic Knee Pain
Knee Osteoarthritis (KOA) is a major cause of pain and disability, particularly in those of increasing age and body fat. As there are no very effective therapies for KOA, disease often progresses until knee replacement surgery is…
- Trial name
- NCT02293889
- Testing
- Vitamin D3 2000IU/daily 3 months, PA intervention People with Osteoarthritis Walking Programme
- Where
- 2 sites in United Kingdom
- Volunteers
- 45 people
- Sponsor
- Newcastle University
Undernutrition, Elderly Person
Finger Food, Pleasure at Your Fingertips: Randomized Pilot Study, Open-label and Parallel Groups
Food is available in easy-to-grip bites that allow residents in care settings to use their fingers for food. This new way of eating can help limit weight loss, increase food intake, gain independence and improve the enjoyment of…
- Trial name
- PLAID (NCT05389098)
- Testing
- Hand-Eating, Control
- Where
- 2 sites in France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Mild Cognitive Impairment
Board Game Intervention to Improve Cognitive and Daily Functioning
Background: With the rapid rise of the aging population, the number of seniors with mild cognitive impairment (MCI) has increased, and without timely interventions, participants are at high risk of developing dementia.
- Trial name
- NCT04964011
- Testing
- Board game intervention
- Where
- Taiwan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Yang Shang-Yu
Loss of Autonomy
Seniors'Health Paths " PAERPA ",
•Background: PAERPA experimentation implemented in the East-Herault region since September 2017 aims to identify fragility and prevent the risk of loss of autonomy in elderly persons older than 60 years by facilitating…
- Trial name
- PAERPA (NCT04165915)
- Where
- France
- Volunteers
- 137 people
- Sponsor
- University Hospital, Montpellier
Cognitive Decline, Osteoarthritis
Healthy Body & Mind Program for Older Adults Living With Osteoarthritis and Cognitive Decline
The goal of this pilot randomised clinical trial is to compare a 12-week Healthy Body \& Mind Program to usual care in older adults living with cognitive decline and osteoarthritis.
- Trial name
- NCT06070818
- Testing
- Healthy Body & Mind Program
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- The University of New South Wales
Urinary Incontinence, Pelvic Floor Muscle Weakness
The Effects of Pelvic Floor Muscle Training Combined With Otago Exercises in Elderly People With Incontinence
Pelvic floor muscle weakness is one of the most important causes of incontinence. There are many studies supporting that pelvic floor muscle training prevents incontinence and reduces symptom severity, and with A level of…
- Conditions
- Urinary Incontinence, Pelvic Floor Muscle Weakness, Muscle Weakness
- Trial name
- NCT06331039
- Testing
- PFMT, PFMT+Otago
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
COVID-19
A Study to Learn About the Study Medicines (Nirmatrelvir Plus Ritonavir) in People Aged 12 Years or Older With COVID-19 and a Compromised Immune System
The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called Nirmatrelvir/Ritonavir) for the possible treatment of COVID-19.
- Trial name
- NCT05438602
- Testing
- Nirmatrelvir, Ritonavir
- Where
- 84 sites in United States, Australia and 7 more
- Volunteers
- 158 people
- Sponsor
- Pfizer
Dementia
Montessori-Based Activities for Elderly Persons With Dementia
This study will determine whether montessori-based activities can help older adults with dementia become more responsive to others.
- Trial name
- NCT00079651
- Testing
- Montessori-based dementia programming
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- Menorah Park
Sclerosis, Multiple
Effects of Blood Flow Restriction Training on Middle-aged People With Multiple Sclerosis.
To analyze the effects of a resistance training program based on the blood flow restriction modality on muscle strengthening and functionality in people over 45 years of age with multiple sclerosis (MS).
- Trial name
- NCT06061939
- Testing
- Blood Flow Restriction training with Oclussion Cuff.
- Where
- Spain
- Volunteers
- 94 people
- Sponsor
- University of Jaén
Malnutrition, Intestinal Integrity
Changes in Circulatory I-FABP in Elderly Persons in Daily Life
The purpose of this study is to detect changes in circulatory I-FABP values (50% increase) in elderly volunteers following the combination of moderate physical activity and a standard meal.
- Conditions
- Malnutrition, Intestinal Integrity, Intestinal Fatty Acid Binding Protein (IFABP)
- Trial name
- NCT02831400
- Testing
- Walking test, Standard Meal
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Non-muscular Invasive Bladder Cancer
BCG for Therapeutic Use Phase I Clinical Trial
This clinical study adopted a single-arm, open, single-centertrial design. The purpose of this study was to evaluate the safety and tolerability, PK characteristics, shedding and immune response characteristics of BCG for…
- Trial name
- NCT06100653
- Testing
- BCG for therapeutic use
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Healthy Participants, Young Healthy Adults
CanCan Body Composition Study
The aim of this study is to develop a dataset with reference body composition measurements using criterion methods. This dataset will be used to develop new protocols to study patients with cancer.
- Conditions
- Healthy Participants, Young Healthy Adults, Elderly (People Aged 65 or More)
- Trial name
- Cancan (NCT07305753)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Healthy Older Adults, Postural Balance
INDIVIDUALIZED DUAL-TASK TRAINING FOR BALANCE AND MOBILITY IN OLDER ADULTS
The goal of this clinical trial is to prevent functional decline and improve mobility in healthy older adults aged 65 and over. The main questions it aims to answer are: What is the effect of individualized dual-task training on…
- Conditions
- Healthy Older Adults, Postural Balance, Dual Task Exercises in Elderly People, Dual Task Cost
- Trial name
- NCT07448961
- Testing
- Individualized Dual-Task Training, Standardized Dual-Task Training, Single-Task Motor Training
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Sezen Karaborklu Argut
Community-dwelling Elderly
Exploring the Relationship Between ICOPE Framework and Frailty Among Community-dwelling Elderly Individuals
This study aims to (1) compare the assessment outcome of the ICOPE-I and ICOPE-S, and (2) investigate the correlation between both versions of the ICOPE step 1 screening tools and frailty in Taiwan.
- Trial name
- NCT06140212
- Testing
- Montreal Cognitive Assessment (MoCA), Chinese ICOPE screening tool (self-administration and interview versions), Frailty status assessment (Edmonton frail scale and Frailty criteria by Dr. Fried)
- Where
- Taiwan
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Non-small Cell Lung Cancer, Older People
Carbon Ion Radiotherapy for Locally Advanced Lung Cancer in Elderly Patients
To observe the effect and toxicity of carbon ion radiotherapy on local advanced non-small cell lung cancer over 75 years old patients. Systemic therapy could be targeted therapy, chemotherapy or immunotherapy.
- Conditions
- Non-small Cell Lung Cancer, Older People, Carbon Ion Radiotherapy, Radiotherapy Side Effect
- Trial name
- NCT06311981
- Testing
- carbon ion radiotherapy, targeted therapy, single regimen chemotherapy in sequence with radiotherapy
- Where
- China
- Volunteers
- 29 people
- Sponsor
- Jian Chen
Swallowing Disorder
The Effect of Active Breathing Exercises for Elderly People in the Community
The goal of this clinical trial is to explore the impact of Active Breathing Exercises on swallowing function and quality of life in community-dwelling elderly individuals (≥60 year old) with swallowing disorders.
- Trial name
- ABE (NCT06232031)
- Testing
- Active Breathing Exercises
- Sponsor
- Zeng Changhao
Older People
The Effect of Big Amplitude Calisthenic Group Exercises on Balance and Dual Task Performance in Older Adults
The subject of this research is to investigate the effect of high amplitude calisthenic group exercises with music on balance and dual task performance in elderly individuals.
- Trial name
- NCT06713551
- Testing
- Big Amplitude Calisthenic Group Exercise with Music, Big Amplitude Calisthenic Group Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Biruni University
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