Clinical trials: Elderly Persons
Alzheimer Disease, Mild Cognitive Impairment
Evaluation of the Effectiveness and Safety of Transcranial Direct Current Stimulation in Combination With Nasal Near Infrared Stimulation to Improve Cognitive Functions and Quality of Life in Elderly People With Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD).
Alzheimer's disease (AD) and mild cognitive impairment (MCI) are progressive neurodegenerative conditions with limited therapeutic options. Today, around 30 million people worldwide suffer from Alzheimer's dementia.
- Trial name
- NCT07290686
- Testing
- tDCS stimulation, tDCS, iNIRS stimulation
- Where
- Poland
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Aging, Healthy Aging
Physical Fitness in Elderly
Aging decreases the physical fitness levels in living beings. The environmental factors also have a major effect on the physical fitness levels.
- Conditions
- Aging, Healthy Aging, Physical Fitness
- Trial name
- NCT04250870
- Testing
- Senior Fitness Test
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Baskent University
Norovirus Infections, Norwalk Gastroenteritis
Phase III Clinical Trial to Evaluate the Human Norovirus Bivalent (GⅠ.1/GⅡ.4)Vaccine,Recombinant (Hansenula Polymorpha)
The purpose of this study is to evaluate the Efficacy, Safety and Immunogenicity of the Human Norovirus Bivalent (GⅠ.1/GⅡ.4)Vaccine,Recombinant (Hansenula polymorpha) in Healthy People Aged 6 Months to 13 Years After Vaccination
- Trial name
- NCT05916326
- Testing
- Human Norovirus Bivalent (GⅠ.1/GⅡ.4)Vaccine,Recombinant (Hansenula polymorpha)
- Where
- 3 sites in China
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- National Vaccine and Serum Institute, China
Fall, Fractures
Prevention of Falls and Fractures in Old People by Administration of Calcium and Vitamin D. Randomized Clinical Trial
The first objective is to determine the efficacy of calcium and vitamin D supplementation at doses of 1200 mg and 800 IU, respectively, to reduce the incidence of falls and fractures in non-institutionalized elderly people.
- Trial name
- ANVITAD (NCT01452243)
- Testing
- Vitamin D and calcium suplementation
- Where
- Spain
- Volunteers
- 704 people
- Sponsor
- Gerencia de Atención Primaria, Albacete
Older People
The Effects of Moderate Intensity Cycle Ergometer vs. Treadmill Training on Physiological Resilience in Older Adults
Government guidelines suggest that we should all take part in approximately two and a half hours each week of moderate-intensity aerobic exercise.
- Trial name
- MICeT (NCT06955676)
- Testing
- treadmill exercise, cycle ergometer exercise
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Falls
VISIBLE Study (Visual Intervention Strategy Incorporating Bifocal & Long-distance Eyewear)
The purpose of this study is to determine whether the provision of supplementary plain distance glasses for outdoor use to older users multifocal glasses will reduce falls rates over a 12 month period.
- Trial name
- VISIBLE (NCT00350389)
- Testing
- Outdoor use of plain distance glasses with counselling
- Where
- Australia
- Volunteers
- 606 people, healthy volunteers welcome
- Sponsor
- The University of New South Wales
Multiple Chronic Conditions;Diabetes;Hypertension
Effectiveness of Health Literacy Enhancement Program Among Older Persons With Physical Multimorbidity
The study aims to examine the effectiveness of individual and family health literacy enhancement program among older persons with physical multimorbidity. Specific objectives are: 1.
- Trial name
- NCT06313138
- Testing
- The Individual and Family Enhancement Program
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Nantong University
Dementia
Managing Time With Dementia: Effects of Time Assistive Products in People With Dementia
Sweden, like most countries, is undergoing population ageing. This is accompanied by an epidemiologic transition of equal importance, leading to a greater number of people than ever before affected by dementia.
- Trial name
- MTD (NCT03677284)
- Testing
- Time assistive products, Information brochure
- Where
- Sweden
- Volunteers
- 74 people
- Sponsor
- Uppsala University
Mild Cognitive Impairment, Depressive Symptoms
Homebound Elderly People Psychotherapeutic Intervention
This study aims to develop, implement, and assess the feasibility, acceptability, and preliminary efficacy of a 10-week structured and individualized cognitive-emotional intervention program for homebound older adults with Mild…
- Conditions
- Mild Cognitive Impairment, Depressive Symptoms, Anxiety State
- Trial name
- HEPPI (NCT04967378)
- Testing
- HEPPI
- Where
- Portugal
- Volunteers
- 51 people
- Sponsor
- University of Coimbra
Dance Therapy, Self Neglect
Dance and Movement Therapy Techniques in Elderly People
Aim: To investigate the effects of dance and movement therapy or walking interventions for elderly people aged 65 and over who are registered to the family health center located in the city center of Amasya, on the loneliness and…
- Conditions
- Dance Therapy, Self Neglect, Loneliness
- Trial name
- NCT05655455
- Testing
- walking group: 1.group, dance and movement therapy group: 2.group
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Amasya University
COVID-19
Safety and Immunogenicity Study of an Inactivated SARS-CoV-2 Vaccine for Preventing Against COVID-19 in People Aged ⩾60 Years
This study is a randomized, double-blinded, and placebo-controlled phase Ib/IIb clinical trial of the Inactivated SARS-CoV-2 Vaccine to evaluate the safety and immunogenicity of the vaccine in healthy people aged ⩾60 Years.
- Trial name
- NCT04470609
- Testing
- Low dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 28-day schedule, Medium dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 28-day schedule, High dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 28-day schedule
- Where
- China
- Volunteers
- 471 people, healthy volunteers welcome
- Sponsor
- Institute of Medical Biology, Chinese Academy of Medical Sciences
Pressure Injury, Fall Prevention
Clinical Investigation Evaluating the Use of NETSmart Solution , Incorporated to NETSoins Software, in the Care and Support of Elderly People Living in Nursing Homes
NETSmart software is designed to help doctors, nurses and care assistants adapt the care of elderly people living in nursing homes to the following risks: pressure injuries undernutrition interactions between different drugs…
- Conditions
- Pressure Injury, Fall Prevention, Undernutrition, Drug Interaction
- Trial name
- NETSMART DM (NCT07027358)
- Testing
- NETSmart software
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Teranga Software
Insulin Resistance, Obesity
Metformin Effect on Brain Function in Insulin Resistant Elderly People
Alzheimer's disease (AD) and other forms of dementia are rapidly increasing with the aging of the population, and show a clear preponderance among people with insulin resistance.
- Conditions
- Insulin Resistance, Obesity, Obesity, Abdominal
- Trial name
- NCT03733132
- Testing
- Metformin Hydrochloride
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Frail Elderly People Hospitalized
Predictors of Physical Improvement in Frail Hospitalized Elders After Nutrition and Exercise
This study aims to evaluate whether a 12-week program combining oral nutritional supplements (ONS) with resistance exercises can improve nutritional status, muscle strength, and physical mobility in hospitalized older adults with…
- Trial name
- NCT07429630
- Testing
- Combined ONS and Resistance Training Program
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Zhejiang Hospital
Healthy
Association Between the Individual Chronotype and Body Composition in German Students - The ChroNu Study
Chronotype is defined as the midpoint of sleep and describes a biological construct of an organism's temporal organisation. Misalignment between the individual chronotype and socially determined schedules may result in a…
- Trial name
- ChroNuCohort (NCT04302922)
- Where
- Germany
- Volunteers
- 327 people, healthy volunteers welcome
- Sponsor
- Paderborn University
Metabolic Abnormality, Metabolic Disorders
Evaluating Metabolic Health in People Aged 18 to 60 by Nutrilite Metabolic Health Index
The goal of this observational study is to evaluate Metabolic Health by fit analysis between calculated Nutrilite Metabolic Health Index and the result of Metabolomics analysis from blood plasma samples in healthy adult…
- Trial name
- NCT07161557
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Amway (China) R&D Center
Fall, Old Age; Atrophy
Measuring the Impact of a Multimodal Intervention on Falls and Fear Falls Among People 65 Years Old, Residents at Home
Measuring the Impact of a Multimodal Intervention on Falls and Fear Falls among People 65 Years Old, Residents at Home in Boulogne city
- Trial name
- KitPA (NCT03968536)
- Testing
- fall prevention
- Where
- France
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Gérond'if
Mild Cognitive Impairment (MCI), Dementia
Exercise Workshop, Skill-Based Art Approaches, and Awareness Studies for Elderly Individuals
Purpose: The aim of the project is to contribute to the physical, social, and psychological well-being of elderly individuals with cognitive impairment within a multidisciplinary approach framework, and to increase the level of…
- Conditions
- Mild Cognitive Impairment (MCI), Dementia, Alzheimer Disease, Geriatric Rehabilitation
- Trial name
- NCT07016893
- Testing
- Healthy aging interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Istanbul University - Cerrahpasa
Old Age; Cachexia, Dietary Habits
The Nutritionist's Educational Intervention on the Protein Intake in Hospitalized Elderly People
The food intake is often compromised in the elderly, and during hospitalization, dietary restrictions may be imposed, making them more susceptible to the risk of malnutrition and sarcopenia.
- Conditions
- Old Age; Cachexia, Dietary Habits, Sarcopenia, Protein Malnutrition
- Trial name
- NCT05502445
- Testing
- educational intervention
- Where
- Brazil
- Volunteers
- 58 people
- Sponsor
- Hospital Israelita Albert Einstein
Aged
The Foot Posture and Falling Risk in Older People
This research will be conducted to examine the relationship between the foot postures and fall risks of elderly individuals living in nursing homes, to identify the factors that most affect the risk of falling, and to inform…
- Trial name
- NCT06153732
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Bahar Anaforoglu Külünkoglu
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