Clinical trials: Elderly Persons
Cognitive Function, Metabolic Improvements
B-vitamins Treatment for Improvement of Cognitive Function
Observation studies documented a correlation between plasma concentrations of homocysteine and cognitive decline with age. The study hypothesis was that high doses of B-vitamins (as effective homocysteine lowering treatment) can…
- Trial name
- NCT01095211
- Testing
- B-vitamin complex
- Where
- Germany
- Volunteers
- 79 people
- Sponsor
- Universität des Saarlandes
Multimorbidity
Personal Resources of Elderly People With Multimorbidity
PREFER II aims at developing psychological targeted theory- and evidence-based intervention components, which support older people with multiple illnesses in performing more physical activity.
- Trial name
- PREFER (NCT01577134)
- Testing
- Social-cognitive resource intervention, no intervention
- Where
- Germany
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- German Centre of Gerontology
Coronavirus
Recombinant New Coronavirus Vaccine (CHO Cells) to Prevent SARS-CoV-2 Phase I Clinical Trial (≥60 Years Old)
Popular topic: Phase I clinical trial of recombinant new coronavirus vaccine (CHO cell) (≥60 years old) Research purpose: Main purpose: To evaluate the safety and tolerability of different doses of recombinant new coronavirus…
- Trial name
- NCT04550351
- Testing
- Biological/Vaccine: Recombinant new coronavirus vaccine (CHO cell) low-dose group, Biological/Vaccine: Recombinant new coronavirus vaccine (CHO cells) high-dose group
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Simulation Training, Anticoagulant Drugs
E-learning to Improve Oral Anticoagulant Use in Hospitalized Older People With AF
Atrial Fibrillation (AF) is the most common cardiac arrhythmia and the main cause of cardioembolic stroke. Oral Anticoagulation (OAC) has been shown to significantly prevent AF-related thromboembolism, however, despite convincing…
- Conditions
- Simulation Training, Anticoagulant Drugs, Elderly, Atrial Fibrillation
- Trial name
- SIM-AF (NCT03188211)
- Testing
- E-learning educational program, Control
- Where
- 20 sites in Italy
- Volunteers
- 247 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Dementia
The Effect of a Comprehensive Dementia Education Program on Improving Attitudes Toward People Living With Dementia
This randomized controlled trial focuses on Indonesian nursing students and examines the effectiveness of virtual reality (VR) dementia education programs. The study addresses the following research questions: 1.
- Trial name
- VReducationRCT (NCT07265856)
- Testing
- Comprehensive VR Program, Conventional Lecture Program (Non-VR)
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universitas Airlangga
COPD, Healthy Older Adults
Acute Effects of Supramaximal High-Intensity Interval Training in People With COPD
High-intensity exercise is essential for optimal development of cardiorespiratory fitness and health. This is, however, challenging for most people with chronic obstructive pulmonary disease (COPD) due to ventilatory limitations…
- Trial name
- COPD-HIIT-AC (NCT05874999)
- Testing
- Supramaximal High-Intensity Interval Training at 60% of MPO6, Moderate-Intensity Continuous Training, Supramaximal High-Intensity Interval Training at 80% of MPO6
- Where
- Sweden
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Umeå University
Healthy, Thalamic Pain Syndrome
Gait Parameters Analysis in Post-stroke Patients and in Elderly Fallers
A large proportion of falls in older people occurs when walking. Most studies have recently demonstrated correlation between the variations in spatiotemporal gait parameters and fall risk in elderly and in several diseases.
- Conditions
- Healthy, Thalamic Pain Syndrome, Fallers
- Trial name
- GAITRITE (NCT01443052)
- Testing
- Gait analysis
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infection, Bacterial
Effect of a Infection Control Program on the Reduction of Bacterial Contamination on NG Tube Feeding in RCHEs
Septicaemia is a potential complication of nasogastric (NG) tube feeding contamination (Leanne, 2014; Anderton, 2000) and a major cause of morbidity and mortality in residential care home for elders ( RCHEs) (Leanne, 2014).
- Trial name
- NCT04075344
- Testing
- Multimodal Infection control programme
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Depressive Symptoms
Collaborative Stepped-Care and Productive Ageing Program for Older People With Depressive Symptoms
The Jockey Club Holistic Support Project for Elderly Mental Wellness (JC JoyAge) has developed and implemented a collaborative stepped care model for older persons at-risk of or with depression in four districts in Hong Kong…
- Trial name
- JCJoyAge2 (NCT04863300)
- Testing
- Collaborative stepped care and peer support
- Where
- 43 sites in Hong Kong
- Volunteers
- 5,239 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Healthy
Diet and the Aging Brain
We investigate whether a change in diet could provide positive effects on general brain functions in healthy elderly people.
- Trial name
- NCT00463255
- Testing
- diet
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Suicide
Suicide in People Aged 45-60: A Case-control Psychological Autopsy Study
The purpose of this study is to learn about the possible causes of the negative trend in suicide rates in both males and females aged 45-60 in Flanders, Belgium. This will be carried out using a psychological autopsy study.
- Trial name
- NCT03703128
- Where
- Belgium
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University Ghent
Diabetes Mellitus
DiaFrail: A Short Duration Study in Older People ( DIAFRAIL Study)
1. Many patients with type 2 diabetes are not at glycaemic goal and require additional therapy in order to reduce vascular risk and improve symptom control 2.
- Trial name
- DiaFrail (NCT02484209)
- Testing
- Metformin, Glimepiride
- Sponsor
- Diabetes Frail Ltd
Mild Cognitive Impairment
Reducing Sedentary Behaviour and Cognition in Older People
Introduction Sedentary behaviour refers to activities of low energy expenditure in lying and sitting positions. Examples include driving, watching television, playing cards, puzzles and working on a computer.
- Trial name
- NCT04464538
- Testing
- WALC-R, Information leaflet
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Anglia Ruskin University
Elderly (People Aged 65 or More), Hip Fracture
The Role of Precision Anesthesia Strategy on Perioperative Organ Protection in Hip Surgery [PASPOP]
The goal of this clinical trial is to investigate the effect of three anesthetic strategies on organ protection in elderly patients undergoing hip fracture surgery.
- Conditions
- Elderly (People Aged 65 or More), Hip Fracture, Delirium - Postoperative, Organ Protection
- Trial name
- PASPOP (NCT06696404)
- Testing
- Combined Lumbar Plexus and Sacral Plexus Block, iliac fascial block, spinal anesthesia
- Where
- 2 sites in China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Metabolic Syndrome, Predisposition to Cardiovascular Disease
Analysis of the Postprandial Effects of a Vegetable Protein Mixture Rich in Arginine, Cysteine and Leucine on Endothelial Dysfunction and Inflammation at Low Noise in Elderly People With Cardiometabolic Risk
By 2050, the expanding world population will consume two-thirds more animal protein than it consumes today. The increase in chronic diseases associated with the generalization of these consumption patterns tend to understand the…
- Trial name
- P-PROBS CM (NCT04923555)
- Testing
- Vegetable proteins (VP) rich in leucine, cystein, arginine, Animal proteins (AP), No protein (T)
- Where
- France
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Elderly Persons
Hypoxia and Exercise in the Elderly
Ageing is the primary risk factor for most chronic diseases including type 2 diabetes mellitus. Sarcopenia and muscular mitochondrial dysfunction with aging are crucial mechanisms leading to decreased exercise tolerance and…
- Trial name
- NCT02196623
- Testing
- Hypoxic exercise, Normoxic Exercise
- Where
- Germany
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Influenza, Human, Influenza, Human Prevention
Phase III Clinical Trial of Quadrivalent Influenza Virus Split Vaccine
This is a randomized, blinded, active-controlled phase III clinical trial to evaluate the immunogenicity and safety of the Quadrivalent Influenza Virus Split Vaccine (QIV) in subjects (aged 3 years and above).
- Conditions
- Influenza, Human, Influenza, Human Prevention, Influenza a, Influenza B
- Trial name
- NCT06800950
- Testing
- QIV, QIV Control
- Where
- 3 sites in China
- Volunteers
- 4,400 people, healthy volunteers welcome
- Sponsor
- Institute of Medical Biology, Chinese Academy of Medical Sciences
ELDERLY PEOPLE
Effect of a Multi-component Training Program With Progressive Phases on the Elderly
The increase in life expectancy worldwide, added to the decrease in birth rates, has resulted in an increase in the aging population.
- Trial name
- NCT04118478
- Testing
- multi-component phased training program
- Where
- Spain
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Postural, Defect
TENS and Taping for Older People
Aim: To examine the acute effects of transcutaneous electrical nerve stimulation (TENS) and Kinesio Taping (KT) on lower limb joint proprioception, static standing balance, limits of stability and functional balance performance…
- Trial name
- NCT05596110
- Testing
- TENS and KT
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Balance; Distorted
Influence of an Exercise Program in the Elderly Balance
This study has the objective to determinate the effectiveness of a specific exercise program on balance and functional capacity of the daily activities of institutionalized elderly.
- Trial name
- NCT03521752
- Testing
- Specific Exercise Program
- Volunteers
- 21 people
- Sponsor
- Cooperativa de Ensino Superior, Politécnico e Universitário
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