Clinical trials: Elders
Influenza
A Clinical Trial With Influenza A/H1N1 Vaccines
A single center, stratified, randomized and double-blind phase IV clinical trial is to be conducted in healthy elders (equal to or more than 61 years), adults (18-60 years), adolescents (12-17 years) and children (3-11 years) to…
- Trial name
- NCT00956111
- Testing
- split-virion, adjuvanted H1N1 vaccine of 7.5 μg per dose, split-virion, adjuvanted H1N1 vaccine of 15 μg per dose, split-virion, non-adjuvanted H1N1 vaccine of 15 μg per dose
- Where
- China
- Volunteers
- 1,614 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
Elders
Respiratory Training Intervention
This study aims to examine the effect of abdominal diaphragmatic breathing combined with incentive spirometer breathing training on the lung capacity of elderly community residents.
- Trial name
- NCT05969678
- Testing
- breathing training
- Where
- Taiwan
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Elders
Turkish Version of Lower Extremity Functional Scale in Elders
This study was conducted in order to analyze the validity and reliability, and psychometric properties of the Turkish version of the Lower Extremity Functional Scale (LEFS-T) in elder adults.
- Trial name
- NCT05035329
- Testing
- Outcome measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Elder
Pharmacokinetics of Leritrelvir(Ray1216) in Elder Participants
The purpose of this study is to assess the safety, tolerability and PK of Leritrelvir in elder participants
- Trial name
- NCT06169085
- Testing
- Leritrelvir
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Guangdong Raynovent Biotech Co., Ltd
Depression, Anxiety, Fatigue
Feasibility Study of a Modified Yoga Program for Elders
The purpose of this study is to determine whether a modified yoga program helps improve pain and function in elders age 65 years or older living in an assisted living community.
- Conditions
- Depression, Anxiety, Fatigue, Pain, Chronic, Sleep
- Trial name
- NCT04343625
- Testing
- Modified yoga class
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Root Caries
Prevention and Arrest of Root Caries Lesions with High Fluoride Concentration Mouthwash Versus Normal Fluoride Concentration Mouthwash in Elderly Patients
The study evaluats the effectiveness of regular fluoride 220 ppm F with erythritol and high fluoride 500 ppm F with erythritol mouthwashes against a placebo (regular fluoride 220 ppm F mouthwash) in the prevention of new root…
- Trial name
- NCT06723054
- Testing
- regular fluoride 220 ppm F mouthwash without erythritol, regular fluoride 220 ppm F mouthwash with erythritol, high fluoride 500 ppm F mouthwash with erythritol
- Where
- Switzerland
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Murali Srinivasan, Dr. med. dent., BDS, MDS, MBA, MAS
Aging
CARESSES Testing and Evaluation Phases
The aim of this study is to conduct and evaluate a controlled experimental trial aimed at exploring whether, to what extent and how a socially-assistive Pepper robot that operates on a unique CARESSES cultural competence solution…
- Trial name
- CARESSES (NCT03756194)
- Testing
- Socially-assistive Pepper robot with a CARESSES cultural competence solution, Socially-assistive control Pepper robot with an alternative CARESSES solution
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Bedfordshire
Falls
Dane County Safety Assessment for Elders (SAFE) Research Study
This 3-year collaborative project will develop, implement, and test a comprehensive approach to the prevention of falls among high-risk older adults in Dane County, Wisconsin through two complementary strategies: 1.
- Trial name
- NCT00205114
- Testing
- Individualized multifactorial intervention for community-living high-risk older adults, Health professional education program about fall prevention
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Elder Abuse
Feasibility of VOICES Elder Abuse Intervention in Primary Care Setting (VOICES-PC Feasibility)
To test an interactive intervention to screen for Elder Abuse and Mistreatment (EM) in the Primary Care (PC) setting to promote self-identification and self-disclosure of EM.
- Trial name
- VOICES-PC (NCT05224843)
- Testing
- Virtual cOaching in making Informed Choices on Elder Mistreatment Self-Disclosure (VOICES)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yale University
Caregivers, Family Relations
Knowledge and Interpersonal Skills to Develop Exemplary Relationships
This pilot study will test the effect of an online asynchronous psychoeducational intervention to improve relationship quality and prevent verbal-type elder mistreatment in caregiving dyads.
- Conditions
- Caregivers, Family Relations, Domestic Violence, Elder Abuse
- Trial name
- KINDER (NCT03593564)
- Testing
- KINDER
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Cognitive Impairment, Dementia
Randomized Trial of Exercise and Social Interaction in a Community-Based Sample of Non-Demented Chinese Elders
A pilot randomized clinical trial was conducted in a random sample of 120 non-demented Chinese elders (ages 60-79) living in a defined community in Shanghai, China to compare the effects of interventions (fast walking, Tai Chi…
- Conditions
- Cognitive Impairment, Dementia, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- SCIBHI (NCT01696019)
- Testing
- Fast walking, Tai Chi, Intellectual stimulation
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Muscular Atrophy, Sensitivity Training Groups
Effects of Inspiratory Muscle Training in Elders
Aging causes anatomical and physiological changes in the respiratory system and respiratory muscle strength with decline in its maximum function.
- Conditions
- Muscular Atrophy, Sensitivity Training Groups, Aging
- Trial name
- NCT01791010
- Testing
- Inspiratory muscle training
- Where
- Brazil
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Elder
Foodservice Robots Engaging Senior Health
The purpose of this study is to find better ways to help older adults living in rural areas get access to fresh fruits and vegetables.
- Trial name
- FRESH (NCT07896408)
- Testing
- Robot-Assisted Last-Mile Food Delivery (RALMFD)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Sleep Disturbances, Depression
Neurobiological Investigations of Mindfulness, Depression and Sleep Disturbances in Medical Staffs and Community Elders
The research team proposes a multi-year study with the first year focusing on the developmental phase. In this initial phase, we aim to recruit 40 participants (including healthcare staff and older adults) from Shuang-Ho Hospital…
- Trial name
- NIMDS (NCT07179172)
- Testing
- Mindfulness-Based Stress Reduction (MBSR) 8-Week Program
- Where
- Taiwan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Memory Deficits, tACS
tACS Improves Memory in Elders With Subjective Memory Complaints
Subjective memory complaints (SMC), the main cognitive component of which is event memory, is a predictor of Alzheimer's disease in elderly people.
- Trial name
- NCT05569902
- Testing
- active tACS
- Where
- Iran
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Tehran
Elderly
Eldercare Technology in a Silver Culture Village
The aim of this project is to create ten smart devices that involve combining an interactive art environment with IC technology, arts and health administration.
- Trial name
- NCT03084107
- Testing
- Questionnaire
- Where
- Taiwan
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Pneumonia
The Effect of Leukocyte Dna mEthylation and micRoBIOME Diversity on Host Defense Mechanisms During Community-acquired Pneumonia (ELDER-BIOME)
Community-acquired pneumonia (CAP) represents a major health care problem and mortality and morbidity associated with severe pneumonia remain considerable, despite state of the art care.
- Trial name
- ELDER-BIOME (NCT02928367)
- Testing
- rectal swab, nasopharyngeal swab, blood draw
- Where
- Netherlands
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Motoric Cognitive Risk Syndrome
ENGAGE for Brain Health
Age-related cognitive decline has a profound impact on the daily functioning of older adults, their families and healthcare systems.
- Trial name
- ENGAGE-B (NCT03750682)
- Testing
- Physical Activity (PA) Intervention, Healthy Aging Education (HE) Intervention
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Tufts University
Depression
Cognitive Correlates of Antidepressant Treatment Response in Elders
Major depression is a very common health problem affecting older persons. The present standard of treatment is with medications called "antidepressants".
- Trial name
- NCT01477268
- Testing
- Zoloft (antidepressant)
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Root Caries
Effectiveness on SDF Solution and PVP-I Combined NaF Varnish in Preventing Root Caries in Elders
The main objective of this study is to compare the effectiveness and cost-effectiveness of 4-monthly application of 10% povidone iodine solution followed by 5% sodium fluoride varnish with those of annual application of 38%…
- Trial name
- NCT03654820
- Testing
- PVP-I solution combined with NaF varnish, SDF solution
- Where
- China
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong