Clinical trials: Elective
Surgery
Goal-directed Fluid Management Versus Conventional Fluid Management in Laparoscopic Hysterectomy
Fluid management is critical in patients undergoing surgery. Goal-directed fluid management (GDFM) protocols have been shown to decrease the length of hospital stay.
- Trial name
- NCT03970928
- Testing
- PVI
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Conscious Sedation, Procedural Sedation
Propofol vs Remifentanil for Sedation in Gastroscopy
This prospective randomized study aims to compare propofol and remifentanil for sedation during elective diagnostic gastroscopy.
- Trial name
- ROPOGAST (NCT07336628)
- Testing
- Propofol (Astra-Zeneca), Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Postoperative Sore Throat, Cough, Hoarseness, Thyroid and Parathyroid Surgery
Sore Throat After Open Neck Elective Surgery
This randomized clinical trial aims to evaluate the effectiveness of two medications-hydrocortisone ointment and lidocaine solution-applied to the endotracheal tube in reducing postoperative throat pain, hoarseness, and cough…
- Trial name
- STONES (NCT07124650)
- Testing
- Hydrocortisone Acetate 1% Ointment, Lidocaine hydrochloride 0,05% with chlorhexidine
- Where
- Russia
- Volunteers
- 764 people
- Sponsor
- Saint Petersburg State University, Russia
Pediatric Sedation, Clonidine Sedation
Premedication in Children: a Clinical Trial Comparing Oral Ketamine and Oral Clonidine With Respect to Sedation Level and Opioid Consumption in Pediatrics Undergoing Elective Lower Abdominal Day-case Surgery.
Aim of the work Is to compare between oral ketamine and oral clonidine regarding the level of sedation pre and postoperatively in addition the need of opioids administration intraoperative in children undergoing elective lower…
- Conditions
- Pediatric Sedation, Clonidine Sedation, Ketamine Sedation
- Trial name
- NCT07461376
- Testing
- Oral Clonidine (OC)
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cirrhosis, Umbilical Hernia
Elective Umbilical Hernia Repair in Patients With Cirrhosis
Liver cirrhosis is a frequent and severe chronic disease. About 20 % of patients with liver cirrhosis develop umbilical hernias. In comparison, the prevalence in the general population is around 2 %.
- Trial name
- NCT04687579
- Testing
- Screening, Preoperative optimization, Umbilical hernia repair
- Volunteers
- 51 people
- Sponsor
- Hvidovre University Hospital
Elective Major Abdominal Surgery
Lidocaine Infusion for Major Abdominal Pediatric Surgery
In this study, the investigators hypothesized that perioperative i.v. infusion of lidocaine in major abdominal pediatric surgery, may have a beneficial effect on hemodynamic and hormonal responses.
- Trial name
- NCT01387568
- Testing
- Lidocaine Infusion, saline Infusion
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Acute Kidney Injury, Obesity
Does the Presence of Preoperative Proteinuria Predict Postoperative Acute Kidney Injury in Obese Patients Undergoing Elective Laparoscopic Surgery?
Acute kidney injury (AKI) is a common, but significant complication after elective surgery which is associated with an increased risk of mortality, major adverse cardiac events, prolonged length of hospital stay, and increased…
- Conditions
- Acute Kidney Injury, Obesity, Proteinuria
- Trial name
- NCT02798042
- Testing
- Urine Sample
- Where
- United States
- Volunteers
- 1,434 people
- Sponsor
- NYU Langone Health
Risk
Remembering Risk: Using Visual Risk Display of MINS to Obtain Informed Consent to Undergo Elective Surgery
Disclosure of anticipated risks to individuals considering undergoing an operative procedure is an important aspect of informed consent process.
- Trial name
- NCT04247841
- Testing
- Visual Aid, Scripted Risk Discussion
- Where
- Canada
- Volunteers
- 456 people
- Sponsor
- Dr. Michael McMullen
Anemia, Venous Thrombosis
A Study to Confirm the Safety and Efficacy of Epoetin Alfa (PROCRIT) Administered Perioperatively vs. the Standard of Care in Blood Conservation in Patients Undergoing Major Elective Spinal Surgery (SPINE Study)
This study is designed to investigate the incidence of deep vein thrombosis in patients receiving a perisurgical regimen of epoetin alfa (PROCRIT®) as compared to patients receiving standard of care blood conservation management.
- Trial name
- NCT00211146
- Testing
- epoetin alfa
- Volunteers
- 680 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Postoperative Nausea and Vomiting
Cannabidiol Oil Extract for Prevention of Postoperative Nausea and Vomiting
Cannabidiol oil has been shown to be effective in treating chemotherapy induced nausea and vomiting, but there is limited information on its usefulness in nausea and vomiting that can occur after surgery.
- Trial name
- NCT06137027
- Testing
- Cannabidiol Oil
- Where
- Jamaica
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Infrarenal Abdominal Aortic Aneurysm
Arterial Stiffness, Blood Pressure and Cardiac Output Study
Comparison of non-invasively obtained central blood pressure using SphygmoCor and invasively recorded central blood pressure in patients with an AAA that will be treated with EVAR.
- Trial name
- ABC (NCT03469388)
- Testing
- Pulse wave analyses; central blood presaure parameters
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Rijnstate Hospital
Pruritus
Effect of Granisetron on Morphine Induced Pruritus in Cesarean Section
Neuraxial anesthesia, which includes epidural anesthesia and intrathecal anesthesia, is a frequent anesthetic approach for caesarean delivery and other lower abdominal and lower limb anesthetic procedures.
- Trial name
- NCT03483870
- Testing
- Morphine Sulfate, Granisetron
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Opioid Use, Postoperative Pain
Analgesic Effects of Intrathecal Morphine and Bilateral Erector Spina Plane Block in Elective Cesarean Section
Cesarean section cause severe pain due to surgical incision, abdominal wall retraction and visceral organ movements. Cesarean section can be performed with general anesthesia, spinal anesthesia, epidural anesthesia and combined…
- Trial name
- NCT05698927
- Testing
- Erector Spinae Plane Block (bilaterally, via 20ml % 0.25 bupivacain) and Intrathecal Morphine (100 mcg)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Marmara University
Cerclage, Cervical
Comparison of Cervical Cerclage by Vaginal and by Laparoscopic Transabdominal Routes in the Periconceptional Period
The goal of this observational study is to compare two different surgical techniques of performing elective cervical cerclage in the prevention of preterm delivery, both of which are already widely used in common clinical…
- Trial name
- NCT06788873
- Testing
- Data comparison
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Vaginal Microbiome
Does Elective Amniocentesis Change Vaginal Microbiome?
the aim of this study is to check if elective amniocentesis change vaginal microbiome
- Trial name
- NCT03884361
- Testing
- Vaginal Microbiome as result of aminocentesis
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Pregnancy, Cesarean Section
Gastric Volumes by US in Term Parturients Undergoing CS With and Without Metoclopramide
Our objective is to compare gastric volumes (mL) between women who receive metoclopramide versus placebo prior to scheduled cesarean delivery in appropriately fasted patients.
- Conditions
- Pregnancy, Cesarean Section, Aspiration
- Trial name
- NCT05033041
- Testing
- Study drug metoclopramide
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Northwestern University
Atrial Fibrillation
FINnish CardioVersion Study II
This is a retrospective multi-center patient cohort study investigating patients with persistent atrial fibrillation (AF) and elective cardioversion (ECV).
- Trial name
- FinCV2 (NCT02850679)
- Where
- Finland
- Volunteers
- 1,342 people
- Sponsor
- University of Turku
Intrauterine Device
Misoprostol for Cervical Ripening Before Copper Intrauterine Device Removal
Intrauterine devices are the most common used method of contraception in the world, mostly in developing countries, because they offer long-term, reversible and relatively safe contraception.
- Trial name
- NCT03600064
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Intra-abdominal Surgery
Stem Cells Found in the Abdominal Cavity in Humans
The purpose of this research study is to determine the genotype (genetic composition) and phenotype (physical appearance) of cells derived from the abdominal cavity to determine whether stem cells are present.
- Trial name
- NCT00576264
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Cedars-Sinai Medical Center
Wound Infection
Abdominal Wall Closure With Triclosan-coated Suture (TCS09-10)
After open colo-rectal surgery the surgical site infection (SSI) is very high among abdominal surgeries. The goal of the investigators randomized, prospective, multicentric, internet-based study is to compare rate of SSI after…
- Trial name
- NCT01123616
- Testing
- abdominal wall closure
- Where
- Hungary
- Volunteers
- 1 people
- Sponsor
- University of Pecs
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