Clinical trials: Elective
Oophorectomy, Hysterectomy
Bilateral Oophorectomy Versus Ovarian Conservation
This is a pilot study to assess the feasibility of conducting a randomized, blinded, controlled trial of bilateral salpingo-oophorectomy (BSO, removal of the ovaries and fallopian tubes) versus ovarian conservation among…
- Trial name
- NCT01007305
- Testing
- Bilateral salpingo-oophorectomy, Ovarian conservation
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Morbid Obesity in Cardiac Surgery Patients, Postoperative Respiratory Dysfunction
Prophylactic Use of APRV Before Extubation in Morbidly Obese Patients After Cardiac Surgery.
Morbidly obese patients undergoing open heart surgery are at increased risk of breathing problems after removal of the breathing tube due to reduced lung function and chest wall restriction following surgery.
- Conditions
- Morbid Obesity in Cardiac Surgery Patients, Postoperative Respiratory Dysfunction, Mechanical Ventilation Strategies
- Trial name
- APRV-OBESE-CS (NCT07409324)
- Testing
- Airway Pressure Release Ventilation (APRV), Conventional Lung-Protective Mechanical Ventilation
- Volunteers
- 180 people
- Sponsor
- Ain Shams University
Juxtarenal Abdominal Aortic Aneurysm
University of Utah PS-IDE: Physician Modified Endovascular Grafts for the Treatment of Elective, Symptomatic or Ruptured Juxtarenal Aortic Aneurysms
The purpose of this study is to assess the effects of a physician-modified endovascular graft (PMEG) for juxtarenal aortic aneurysms by collecting data on its performance.
- Trial name
- NCT07065760
- Testing
- Endovascular Aneurysm Repair with Physician Modified Endograft
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Cali Johnson
Anesthetic Complication Spinal
Variable Rate Phenylephrine Infusion for Prevention of Spinal-induced Hypotension for Cesarean Delivery
Rapid administration of crystalloid immediately after induction of spinal anesthesia (coload) to be more effective in terms of managing hypotension as compared to administering crystalloid before spinal anesthesia (preload).
- Trial name
- NCT01378325
- Testing
- Phenylephrine, saline
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Smoking Cessation
A Pilot Study Of Smoking Cessation Treatment Including Varenicline In Patients Scheduled For Planned Surgery
It is possible to offer smoking cessation treatment including varenicline to patients scheduled for elective surgery. This study will evaluate whether or not this will enable some patients to quit smoking for up to 4 weeks prior…
- Trial name
- NCT00889720
- Testing
- Varenicline
- Where
- 2 sites in France, Italy
- Volunteers
- 16 people
- Sponsor
- Pfizer
Anxiety State, Child Behavior
Effect of Child Preference for Parental Selection During Induction
Induction of anesthesia can be distressing both for children and their parents. Nonpharmacological behavioral interventions can reduce the anxiety of children without significant adverse effects as seen with sedative drugs.
- Trial name
- NCT05646927
- Testing
- Selection of parent(mother or father) according to children preference, Selection of parent(mother or father) according to randomization
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Compliance, Treatment
Incidence of Compliance to the ASA Preoperative Fasting Guidelines in Elective Surgery
Patients scheduled for elective surgery with general anesthesia, regional anesthesia, or procedural sedation and analgesia will be interviewed about the last time having clear liquid drink light meal regular meal
- Trial name
- NCT04664751
- Testing
- Nil-per-Oral
- Where
- Thailand
- Volunteers
- 309 people
- Sponsor
- Mahidol University
General Anesthesia, Chronic Pain, Postoperative
Risk Factors for Chronic Postoperative Pain After Elective Nephrectomy
Chronic postoperative pain (CPP) is typically defined as pain persisting for 3 months or more after surgery[1]. CPP is a common and increasingly prevalent morbidity, leading to long-term psychological issues, reduced quality of…
- Conditions
- General Anesthesia, Chronic Pain, Postoperative, Acute Pain, Postoperative, Surgery
- Trial name
- NCT06673979
- Testing
- Numeric Rating Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 204 people
- Sponsor
- Istanbul University - Cerrahpasa
Morbid Obesity
The Ultrasound Guided Versus Land-mark Location Method for Performing Spinal Anesthesia in Obese Parturients
This study will be investigated whether an ultrasound-assisted technique is better than a classical land-mark technique to facilitate spinal anesthesia in the lateral position in morbidly obese pregnant women with BMI ≥ 40 who…
- Trial name
- NCT05342922
- Testing
- Ultrasound group, Landmark group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Post Operative Cognitive Dysfunction
Pre-operative Intra-nasal Dexmedetomidine or Insulin for Prevention of Early Post-operative Cognitive Dysfunction in Patients Undergoing Elective Coronary Artery Bypass Graft.
On pump coronary revascularization is a very common leading cause for post-operative cognitive dysfunction regarding patient age grouping and diffuse systemic inflammatory response induced by bypass machine .
- Trial name
- NCT06741566
- Testing
- intranasal saline group, intranasal insulin, Intranasal dexmedetomidine
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Minia University
Infection Prophylaxis in Colo Rectal Surgery
Orally Administered Trimethoprim-sulfamethoxazole and Metronidazole as Prophylaxis of Infection Following Elective Colorectal Surgery
The current standard Swedish infection prophylaxis in colorectal surgery is intravenously administered cefuroxime and metronidazole. this combination is well studied.
- Trial name
- NCT00613769
- Testing
- trimethoprim-sulfamethoxazole + metronidazole, cefuroxime and metronidazole
- Where
- 6 sites in Sweden
- Volunteers
- 1,073 people
- Sponsor
- Halmstad County Hospital
Acute Coronary Syndrome, Percutaneous Coronary Intervention
Bivalirudin in Elderly Patients Undergoing Elective Percutaneous Coronary Intervention.
The study is an investigator-sponsored, prospective, multicenter, randomized, open-label study designed to compare efficacy and safety between bivalirudin and heparin in elderly patients with acute coronary syndrome undergoing…
- Conditions
- Acute Coronary Syndrome, Percutaneous Coronary Intervention, Aging, Anticoagulants and Bleeding Disorders
- Trial name
- NCT04046029
- Testing
- Bivalirudin, Heparin
- Where
- China
- Volunteers
- 240 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Thoracic Aortic Aneurysm, Respiratory Insufficiency
Immunonutrition and Thoracoabdominal Aorta Aneurysm Repair
The purpose of this study is to determine whether immunonutrition and pre operative nutrition can reduce lenght of respirator support, lenght of stay in the ICU and incidence of post operative infections
- Trial name
- NCT00339053
- Testing
- Immunonutrition ( Impact)
- Where
- Netherlands
- Volunteers
- 142 people
- Sponsor
- St. Antonius Hospital
Complication of Anaesthesia During Labour and Delivery
Plethysmographic Variability Index in Post Spinal Anesthesia Hypotension in Cesarean Section
Full term pregnant female patients presented for elective C.S for single viable fetus will be included in this study. Before anesthesia, the patient will be attached to a monitor of: ECG , heart rate, non invasive blood pressure…
- Trial name
- NCT04010318
- Testing
- Spinal Anesthesia
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Coronary Artery Disease
Predictive Value of Allen's Test Result in Elective Patients Undergoing Coronary Catheterization Through Radial Approach
The study will evaluate the feasibility and safety of radial approach in patients undergoing coronary catheterisation without any restrictions based on the results of Allen's test.
- Trial name
- RADAR (NCT00597324)
- Testing
- coronary catheterisation
- Where
- Italy
- Volunteers
- 203 people
- Sponsor
- Marco Valgimigli
Major Elective Abdominal and Thoracic Surgery
Evaluation of Glycocalyx in Major Abdominal and Thoracic Surgery
Background: The glycocalyx is a fundamental component of the endothelial barrier and alterations at this level have been shown to exacerbate the inflammatory response in the microcirculation.
- Trial name
- NCT04900779
- Where
- Spain
- Volunteers
- 117 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Coronary Artery Disease
Aspirin and a PoTent P2Y12 Inhibitor Versus Aspirin and Clopidogrel in Patients Undergoing PCI for Complex Lesion
This study is a prospective, open label, two-arm, randomized multicenter trial to evaluate the efficacy and safety of aspirin plus prasugrel as compared with aspirin plus clopidogrel in patients undergoing elective percutaneous…
- Trial name
- ATTEMPT (NCT04014803)
- Testing
- Dual antiplatelet therapy with a P2Y12 inhibitor plus aspirin
- Where
- 2 sites in South Korea
- Volunteers
- 3,500 people
- Sponsor
- Samsung Medical Center
Prevention of Venous Thrombosis After TKA
Clinical Study on the Efficacy and Safety of Multiple Oral Administrations of SHR2285 Tablets in Patients Undergoing Elective Total Knee Arthroplasty
This study is a multi-center, randomized, open-label, double-blind, positive-controlled phase II clinical study evaluating the efficacy and safety of different doses of SHR2285 tablets vs.
- Trial name
- NCT05203705
- Testing
- SHR2285 tablet, Enoxaparin
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Shanghai Hengrui Pharmaceutical Co., Ltd.
Residual Neuromuscular Blockade, Diaphragm Dysfunction
Diaphragm Ultrasound and Neuromuscular Monitoring for Predicting Early Respiratory Events After Extubation
The goal of this prospective observational study is to learn whether diaphragm ultrasound and quantitative neuromuscular monitoring can predict early respiratory events after extubation in adults having elective surgery under…
- Conditions
- Residual Neuromuscular Blockade, Diaphragm Dysfunction, Postoperative Pulmonary Complications, Airway Extubation
- Trial name
- DIAPHEX (NCT07912437)
- Testing
- Diaphragm ultrasonography4
- Volunteers
- 100 people
- Sponsor
- Mustafa Duran
Severty of Hpotention
Comparing Sitting Versus Lateral Position During Spinal Anesthesia on the Severity of Hypotension:
This study aimed to assess the effect of sitting and lateral positions on the severity of hypotension during the initiation of spinal anesthesia in elective cesarean section. There will be Sitting and Lateral groups in the study.
- Trial name
- NCT06149572
- Testing
- lateral position procedure, sitting position porocedure
- Where
- Ethiopia
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Wollo University
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