Clinical trials: Electric Countershock
Atrial Fibrillation (AF), Heart Failure (HF)
Diagnostic Electrical Cardioversion for Explaining Patient's AF and HF Symptoms
Rationale: The co-existence of Atrial Fibrillation (AF) and Heart Failure (HF) is associated with increased morbidity, mortality, and hospital admissions, significantly contributing to healthcare burden.
- Conditions
- Atrial Fibrillation (AF), Heart Failure (HF), Electrical Cardioversion
- Trial name
- DEEP-AF-HF (NCT07000942)
- Testing
- Electrical cardioversion (ECV)
- Where
- Netherlands
- Volunteers
- 112 people
- Sponsor
- M. Rienstra
Ventricular Arrythmia
Non-vascular ICD Electrode Configuration Feasibility Study
This study is designed to evaluate the energy requirements of two different Nonvascular ICD (NV-ICD) electrode configurations for achieving successful defibrillation of ventricular arrhythmias.
- Trial name
- NCT04809701
- Testing
- Temporary implantation of defibrillation coils and pulse generator, Defibrillation following induction of VA (Configuration A first), Defibrillation following induction of VA (Configuration B first)
- Where
- 3 sites in Chile, Czechia and 1 more
- Volunteers
- 30 people
- Sponsor
- Abbott Medical Devices
Tachyarrhythmia
Study to Verify Proper Detection of Supraventricular Tachyarrhythmia With Single-Lead Dual-Chamber Implantable Cardioverter-Defibrillators (ADRIA)
A unique single-lead dual-chamber implantable cardioverter-defibrillator (ICD) system (produced by Biotronik, Germany) features a conventional electrode in the ventricle (anchored in the ventricular apex) and a floating electrode…
- Trial name
- NCT00324662
- Testing
- Implantable cardioverter-defibrillator
- Where
- 10 sites in Germany, Switzerland
- Volunteers
- 260 people
- Sponsor
- Biotronik SE & Co. KG
Atrial Flutter
Antero-posterior Versus Antero-lateral Electrode Position for Electrical Cardioversion of Typical Atrial Flutter
The aim of this study is to identify the one electrode position out of two most commonly used for external electrical cardioversion of typical atrial flutter, which needs less delivered energy and less needed number of shocks for…
- Trial name
- APOVERSAL (NCT00860314)
- Testing
- external electrical cardioversion (with antero-posterior electrode position), external electrical cardioversion (with antero-lateral electrode position)
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Ventricular Arrythmia, Ventricular Tachycardia
Sub Chronic Evaluation for ATP With an Extravascular Placed ICD Lead (STEP ICD) Study
STEP ICD is a premarket, exploratory, early feasibility, interventional study designed to evaluate the preliminary safety and performance of the Investigational Devices.
- Conditions
- Ventricular Arrythmia, Ventricular Tachycardia, Ventricular Fibrillation
- Trial name
- NCT05791032
- Testing
- AtaCor EV-ICD Lead
- Where
- Paraguay
- Volunteers
- 21 people
- Sponsor
- AtaCor Medical, Inc.
Persistent Atrial Fibrillation
Acupuncture in Persistent Atrial Fibrillation
The aim of this trial is to evaluate the effect of acupuncture on prevention of atrial fibrillation (AF) recurrence after electrical cardioversion (EC) for persistent AF patients resistant to the antiarrhythmic drugs (AADs).
- Trial name
- NCT02110537
- Testing
- Active Acupuncture, flecainide
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Kyunghee University Medical Center
Atrial Fibrillation
n-3 Polyunsaturated Fatty Acids (PUFAs) in the Prevention of Atrial Fibrillation
The purpose of this study is to determine the effect of n-3 PUFAs in addition to amiodarone and renin-angiotensin-aldosterone system (RAAS) inhibitors on the maintenance of sinus rhythm after electrical conversion in patients…
- Trial name
- NCT01198275
- Testing
- n-3 PUFAs, RASS inhibitors and/or RAS blockers, Amiodarone
- Where
- Italy
- Volunteers
- 199 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Cardiomyopathy, Heart Failure
Evaluating Myocardial Injury for Defibrillation Threshold Testing Methods for ICD Implantation
The objective of this study is to evaluate myocardial injury, if any, as quantified by cardiac markers (Troponin-T) in defibrillation threshold (DFT) testing during implantation of implantable cardioverter defibrillators (ICDs)…
- Conditions
- Cardiomyopathy, Heart Failure, Cardiac Arrhythmia
- Trial name
- ULV (NCT02111993)
- Testing
- Standard Defibrillation Testing, Upper Limit of Vulnerability Testing
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Diego
Persistent Atrial Fibrillation
Evaluation of Two Different Regimens of the Antiarrhythmic Drug Amiodarone to Maintain Normal Sinus Rhythm After Electrical Cardioversion in Patients With Persistent Atrial Fibrillation
--- The goal of this clinical trial is to learn if reduced doses of amiodarone can treat atrial fibrillation (AF) effectively while minimizing toxic side effects in patients with persistent AF after electrical cardioversion.
- Trial name
- PERIVERSION-2 (NCT07273994)
- Testing
- Amiodarone Hydrochloride 200 MG, Amiodarone Hydrochloride 100 MG
- Where
- Spain
- Volunteers
- 312 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Cardioversion
Myocardial Injury Following Elective Direct Current Cardioversion for Atrial Arrhythmias
Researchers are trying to determine if heart injury occurs in subjects who undergo direct current cardioversion.
- Trial name
- NCT04151966
- Testing
- Blood sample collection
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Mayo Clinic
Cardiac Arrest, Resuscitation
Out-of-hospital Cardiopulmonary Resuscitation and AED Feedback
The purpose of this study is to determine whether an online automatic feedback improved CPR quality (No-flow time, compression depth, short-term survival and one year follow up) in this prospective randomised study of…
- Trial name
- NCT00449969
- Testing
- Zoll AED pro
- Where
- Germany
- Volunteers
- 312 people
- Sponsor
- University Hospital Muenster
Atrial Fibrillation
Chemical vs Electrical Cardioversion for Emergency Department Patients With Acute Atrial Fibrillation
Atrial fibrillation (AF) is the most common type of irregular heartbeat in emergency department (ED) patients. If the irregular heartbeat has been present for less than 48 hours, there is a chance that emergency treatment can…
- Trial name
- NCT01994070
- Testing
- Electrical-first, Chemical-first
- Where
- Canada
- Volunteers
- 86 people
- Sponsor
- University of British Columbia
Tachycardia, Ventricular Fibrillation
Safety and Performance Study of the RELIANCE 4-Front Passive Fixation Lead
The objective of this study is to gather data to establish the chronic safety, performance and effectiveness of the RELIANCE 4-FRONT™ Passive Fixation Defibrillation Leads.
- Conditions
- Tachycardia, Ventricular Fibrillation, Ventricular Flutter
- Trial name
- NCT01856491
- Testing
- RELIANCE 4-FRONT™ Passive Fixation lead implantation
- Where
- 11 sites in Germany, Israel and 1 more
- Volunteers
- 167 people
- Sponsor
- Boston Scientific Corporation
Atrial Fibrillation
Safety of Cardioversion of Acute Atrial Fibrillation
The purpose of this study is to investigate the complications of cardioversion of acute (<48 hours duration) atrial fibrillation (AF).
- Trial name
- FinCV (NCT01380574)
- Where
- 3 sites in Finland
- Volunteers
- 7,700 people
- Sponsor
- Turku University Hospital
Cardiac Disease
Combined Amiodarone and Electrical Cardioversion for Postoperative Atrial Fibrillation After Cardiac Surgery
To determine the efficacy of cardioversion and amiodarone for cardiac patients who develop postoperative atrial fibrillation
- Trial name
- NCT01558128
- Testing
- Amiodarone, Cardioversion
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Weill Medical College of Cornell University
Persistent Atrial Fibrillation
Electrical Cardioversion, Ablation or Pace and Ablate for Persistent Atrial Fibrillation
Comparison of (i) catheter ablation, (ii) electrical cardioversion and (iii) pacemaker implantation with AV node ablation for patients over 65 years of age with persistent Atrial Fibrillation.
- Trial name
- CAPAPAF-65 (NCT02528604)
- Testing
- Catheter ablation, Pacemaker and AV node ablation, DC Cardioversion
- Where
- 2 sites in United Kingdom
- Volunteers
- 75 people
- Sponsor
- East Sussex Healthcare NHS Trust
Cardiac Arrest
Biphasic Defibrillation Study: Trial to Compare Fixed Versus Escalating Energy
This study will compare the effect of constant low-level energy [150 joules] to an escalating energy [200-300-360 joules] regimen of biphasic waveform defibrillation on multiple patient outcomes.
- Trial name
- NCT00212992
- Testing
- Fixed lower-energy defibrillation, Escalating higher-energy defibrillation
- Where
- Canada
- Volunteers
- 221 people
- Sponsor
- Ottawa Hospital Research Institute
Atrial Fibrillation and Flutter, Heart Failure
Multimodal Cardiac Imaging Registry in Patients with Atrial Fibrillation
The goal of this observational registry is to collect a curated dataset of multimodal imaging data that will serve for development of artificial-intelligence based solutions for prediction of risk and outcomes in patients with…
- Conditions
- Atrial Fibrillation and Flutter, Heart Failure, Artificial Intelligence (AI), Echocardiography
- Trial name
- IMAGE-AF (NCT06584266)
- Testing
- Transoesophageal echocardiography, Catheter ablation
- Where
- 7 sites in Czechia, Poland
- Volunteers
- 3,000 people
- Sponsor
- University in Zielona Góra
Atrial Fibrillation
A First in Human Evaluation of a Novel Approach to Painless Cardioversion (NAPC) in Patients With Atrial Fibrillation
An assessment of the use of cold therapy to terminate atrial fibrillation.
- Trial name
- NAPC (NCT05324540)
- Testing
- Cool therapy
- Volunteers
- 30 people
- Sponsor
- MediCool Technologies
Atrial Fibrillation
Flecainide-Short Long Study (Flec-SL)
A randomized trial to test the hypothesis that short-term pharmacological reversal of electrical remodeling after cardioversion is equally efficient to prevent recurrent atrial fibrillation as standard long-term antiarrhythmic…
- Trial name
- NCT00215774
- Testing
- Flecainide
- Volunteers
- 760 people, healthy volunteers welcome
- Sponsor
- Atrial Fibrillation Network