Clinical trials: Electric Countershock
Atrial Fibrillation
Canakinumab for the Prevention of Recurrences After Electrical Cardioversion: CONVERT-AF
The purpose of this study is to test the efficacy of a single injection of Canakinumab on AF recurrences within 6 months after electrical cardioversion in patients with persistent AF.
- Trial name
- CONVERT-AF (NCT01805960)
- Testing
- Canakinumab
- Where
- 5 sites in Germany, Switzerland
- Volunteers
- 24 people
- Sponsor
- University Hospital, Basel, Switzerland
Atrial Fibrillation (AF)
Smartphone Based-PPG Assessment of REconversion in Persistent Atrial Fibrillation
This study investigates whether a smartphone application that measures heart rhythm using light, a technique known as photoplethysmography or PPG, can accurately detect when the cardiac arrhythmia atrial fibrillation (AF)…
- Trial name
- SPARE-AF (NCT07752940)
- Testing
- Smartphone-based PPG monitoring
- Where
- 2 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- Ziekenhuis Oost-Limburg
Cardiac Surgical Procedures
Lead Extract Study
The recent expansion of indications for implantable cardioverter defibrillators (ICDs) has changed the population of patients being implanted.
- Trial name
- EXTRACT (NCT01169441)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- St. Paul Heart Clinic
Atrial Fibrillation
Intravenous Cardioversion of Atrial Fibrillation (AF) With AZD1305
This study is being carried out to see which dose of AZD1305 is safe and effective in cardioverting atrial fibrillation into normal heart rhythm.
- Trial name
- NCT00915356
- Testing
- AZD1305
- Where
- 31 sites in Czechia, Denmark and 6 more
- Volunteers
- 228 people
- Sponsor
- AstraZeneca
Sudden Cardiac Death
'Effect of CRT on Defibrillation Threshold Estimates' Study
The purpose of this prospective study is to evaluate the effect of cardiac resynchronization therapy (CRT) on the defibrillation threshold (DFT) estimates in cardiac resynchronization therapy defibrillators (CRT-D) patients.
- Trial name
- NCT00626093
- Testing
- Cardiac Resynchronization Therapy - Defibrillator (CRT-D)
- Where
- 2 sites in United States
- Volunteers
- 77 people
- Sponsor
- Abbott Medical Devices
Atrial Fibrillation
Dronedarone Pattern of Use in Patients Scheduled for Elective Cardioversion (ELECTRA)
Primary Objective: To determine whether daily administration of dronedarone started 5-7 days before cardioversion is superior to dronedarone started only after cardioversion with respect to the absence of symptomatic, ECG…
- Trial name
- NCT01026090
- Testing
- Dronedarone
- Where
- 43 sites in Canada
- Volunteers
- 292 people
- Sponsor
- Sanofi
Out-of-hospital Cardiac Arrest (OHCA)
Trial of Mobile External Defibrillator for Out-of-hospital Cardiac Arrest in Singapore.
The goal of this clinical trial is to learn the feasibility of equipping the volunteer community responders (VCR) with the mobile external automated defibrillators (mAEDs) for the management of adults experiencing out-of-hospital…
- Trial name
- NCT07042061
- Testing
- Mobile external automated defibrillator
- Volunteers
- 1,000 people
- Sponsor
- Singapore General Hospital
Out-Of-Hospital Cardiac Arrest After Initial Successful Resuscitation, Out of Hospital Cardiac Arrest
RESTORE-ZG: Return of Effective Spontaneous Circulation Resuscitation Evaluation Canton of Zug
This study looked at cardiac arrest that happens outside a hospital. Cardiac arrest means the heart suddenly stops pumping blood. When this happens, a person collapses and needs help right away.
- Conditions
- Out-Of-Hospital Cardiac Arrest After Initial Successful Resuscitation, Out of Hospital Cardiac Arrest, Out of Hospital Setting, Defibrillation
- Trial name
- RESTORE-ZG (NCT07750119)
- Testing
- Prehospital resuscitation care
- Where
- Switzerland
- Volunteers
- 240 people
- Sponsor
- Felix Brinkmann
Cardioversion, Atrial Fibrillation
Heart Watch Study: a Pragmatic Randomized Controlled Trial
This will be a prospective multi-center, randomized, controlled trial of 150 patients conducted to assess the impact of individual use of the Apple Watch compared to the Withings Move on patient-reported and clinical outcomes at…
- Trial name
- NCT04468321
- Testing
- Apple Watch, Withings Move
- Where
- 3 sites in United States
- Volunteers
- 105 people
- Sponsor
- Yale University
Infections of the Implanted Material, Endocarditis
Diagnostic Accuracy of 18FDG-PET-CT for Pacing or Defibrillation Lead Infection
With aging of the general population and broadening indications, the number of pacemaker recipients is steadily increasing. The incidence of infections of the implanted material, a dreaded major complication, is also rising.
- Trial name
- ENDOTEP (NCT02251262)
- Testing
- Whole-body 18FDG-PET-CT scan
- Where
- 6 sites in France
- Volunteers
- 235 people
- Sponsor
- University Hospital, Bordeaux
Atrial Fibrillation
Continuous Data Collection and Analysis for Stroke Prevention Using a Wearable Sensor
The purpose of this study is to determine whether a wristband that detects your pulse can detect your heart rate and rhythm similar to electrocardiograms (ECG).
- Trial name
- NCT03441022
- Testing
- Amiigo Watch Only, Amiigo Watch + BodyGuardian
- Sponsor
- Mayo Clinic
Atrial Fibrillation
NATional TUnisian REgistry of Atrial Fibrillation
A non-interventional, national longitudinal study of atrial fibrillation performed with 91 cardiologists.
- Trial name
- NATURE-AF (NCT03085576)
- Where
- Tunisia
- Volunteers
- 910 people
- Sponsor
- Dacima Consulting
Electrical Cardioversion of Atrial Fibrillation, Pharmacological Cardioversion of Atrial Fibrillation
Cerebral Oxygen Saturation Measurement During Cardioversion Because of Atrial Fibrillation
Near infrared spectroscopy (NIRS) is a technique that measures regional cerebral oxygenation in a non-invasive manner. Through the use of near infrared light, the difference between oxygenated and deoxygenated hemoglobin can be…
- Trial name
- NCT02378155
- Testing
- SenSmart Model X-100, Nonin Medical
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Hasselt University
Atrial Fibrillation, SGLT2 Inhibitor
Clinical Impact of SGLT2 Inhibitor After DC Cardioversion in Persistent AF With HFpEF
SGLT2 inhibitors improve outcomes in heart failure across the ejection fraction spectrum, but their effect on maintenance of sinus rhythm after rhythm-control therapy is largely unknown.
- Conditions
- Atrial Fibrillation, SGLT2 Inhibitor, DC Cardioversion
- Trial name
- NCT07776054
- Testing
- SGLT2 inhibitors (Dapagliflozin and Empagliflozin)
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Out-Of-Hospital Cardiac Arrest, Ventricular Fibrillation
DOuble SEquential External Defibrillation for Refractory VF
Despite significant advances in resuscitation efforts, there are some patients who remain in refractory ventricular fibrillation (VF) during out-of-hospital cardiac arrest.
- Trial name
- DOSEVF (NCT04080986)
- Testing
- Double Sequential Defibrillation, Vector Change Defibrillation
- Where
- 6 sites in Canada
- Volunteers
- 405 people
- Sponsor
- Sunnybrook Health Sciences Centre
Out-Of-Hospital Cardiac Arrest
The HeartRunner Trial
The study will assess 30-day survival for cases where volunteer citizen responders ('heart runners') were activated through a smartphone app to retrieve an AED in case of suspected out-of-hospital cardiac arrest (OHCA) versus…
- Trial name
- NCT03835403
- Testing
- Activation of HeartRunners
- Where
- Denmark
- Volunteers
- 2,114 people
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Persistent Atrial Fibrillation, Cardiac Arrhythmia
Investigation of Cardioversion Versus Therapeutic Ablation for Persistent AF (ORBICA-AF)
The main aim of the research is to investigate whether patients undergoing pulmonary vein isolation with catheter ablation for persistent atrial fibrillation (AF) will have lower rates of AF recurrence than those treated by DC…
- Conditions
- Persistent Atrial Fibrillation, Cardiac Arrhythmia, Catheter Ablation
- Trial name
- ORBICA-AF (NCT06096246)
- Testing
- Pulmonary vein isolation, DC Cardioversion, Implantable loop recorder
- Where
- United Kingdom
- Volunteers
- 208 people
- Sponsor
- Barts & The London NHS Trust
Atrial Fibrillation, Atrial Flutter
Left Atrial Thrombus on Transesophageal Echocardiography
The aim of the study is to assess the prevalence of left atrial thrombus in patients with atrial fibrillation (AF) or atrial flutter (AFI), in whom transesophageal echocardiography is performed before AF/AFl cardioversion or…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Transesophageal Echocardiography, Ablation
- Trial name
- LATTEE (NCT03591627)
- Testing
- Transesophageal echocardiography
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Warsaw
Atrial Fibrillation
The Ottawa AF Cardioversion Protocol
Atrial fibrillation is an abnormal heart rhythm in which the top chambers of the heart (the atrial chambers) beat very fast. Electrical cardioversion is a technique to convert heart rhythm from AF to normal rhythm.
- Trial name
- NCT02192957
- Testing
- Lifepak 20E Defibrillator, Licence No: 61944
- Where
- Canada
- Volunteers
- 389 people
- Sponsor
- David Birnie
Atrial Fibrillation
Single vs. Dual-DCCV in Obese Patients
Currently, the usual initial strategy for direct current cardioversion (DCCV) typically involves delivering 200J of electricity between two pads placed in the anterior and posterior positions (i.e., one on the chest and one on…
- Trial name
- NCT04539158
- Testing
- Direct Current Cardioversion
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Dr. Daniel P Morin, MD MPH FHRS