Clinical trials: Electrocardiograph
Coronary Artery Disease
A Phase I Study in Healthy Volunteers to Evaluate the Safety of CardioPET™ in Detection of Coronary Artery Disease
Safety and dosimetry of CardioPET™ will be evaluated in normal healthy volunteers and CAD subjects both male and female between the ages of 50-85.
- Trial name
- NCT00413647
- Testing
- CardioPET
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Fluoropharma, Inc.
Coronary Heart Disease, Arrhythmia
ECG and VCG in Dependence of Body Posture
The electrocardiogram (ECG) is an important diagnostic procedure in medicine mainly to detect circulation disorders and problems of the spread of the electrical heart impulse.
- Trial name
- EVER (NCT02094989)
- Testing
- posture dependence of VCG-ECG-transformation
- Where
- Switzerland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
Pulmonary Embolism (Diagnosis), Respiratory Failure With Hypoxia
Screening for Pulmonary Embolism Using Single-channel Electrocardiogram
It is a prospective, controlled, single-center, observational, non-randomized study. The study is planned to include at least 500 patients 18 years old and older (300 patients in the training sample and 200 patients in the test…
- Conditions
- Pulmonary Embolism (Diagnosis), Respiratory Failure With Hypoxia, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- NCT07412418
- Where
- Russia
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Healthy
Performance and Accuracy of an AI Enhanced Smart Watch Single Lead ECG
The purpose of this study is to show the artificial intelligence enhanced single-lead ECG Apple Watch has similar, robust performance comparable to an AI enhanced 12 lead ECG and AI enhanced single lead (LI) of a 12 lead ECG.
- Trial name
- PROCESS (NCT05450809)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Drug Toxicity
Double-Blind Randomized Crossover Trial to Access Electrocardiogram Effects of HPN-100
Arm 1: Primary Objective: To determine the safety and tolerability of multiple ascending, supratherapeutic doses of HPN-100. Arm 2: Primary Objective: To assess the effects of steady-state levels of HPN-100 metabolites (4…
- Trial name
- NCT01135680
- Testing
- HPN-100, Moxifloxacin
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Amgen
HIV Infections
Effect of Therapeutic and Supratherapeutic Oral Doses of GSK3640254 on Cardiac Conduction Compared to Placebo and a Single Oral Dose of Moxifloxacin
This study will aim to evaluate the effect of therapeutic and supratherapeutic oral doses of GSK3640254 on cardiac conduction compared to placebo and a single oral dose of Moxifloxacin in healthy adult participants.
- Trial name
- NCT04563845
- Testing
- GSK3640254, Moxifloxacin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Healthy
A Study to Assess Electrocardiogram Results in Healthy Volunteers Receiving Canagliflozin (JNJ-28431754)
The purpose of this study is to assess the effect of canagliflozin (JNJ-28431754) on electrocardiogram results (recordings of the electrical activity of the heart) in healthy volunteers after a single therapeutic dose (300 mg)…
- Trial name
- NCT01787357
- Testing
- Canagliflozin (JNJ-28431754), Moxifloxacin
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Swimming Induced Pulmonary Edema (SIPE), Pulmonary Edema
Cardiac Function in Swimming-Induced Pulmonary Edema (SIPE)
Acute or chronic cardiac dysfunction could be a contributing factor to swimming-induced pulmonary edema (SIPE). Knowledge on cardiac function in SIPE is limited and recommendations for cardiac evaluation of patients with SIPE are…
- Conditions
- Swimming Induced Pulmonary Edema (SIPE), Pulmonary Edema, Lung Diseases, Heart Function Tests
- Trial name
- NCT05391737
- Testing
- Echocardiography, Electrocardiogram (ECG), Cardiac biomarkers
- Where
- Sweden
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Dalarna County Council, Sweden
Electrocardiography (ECG), Clinical Competence
Gamification Versus E-Learning for Electrocardiogram Education
This randomized controlled study aims to compare the effectiveness of a gamification educational method and an e-learning educational method for electrocardiogram (ECG) education.
- Trial name
- NCT07646236
- Testing
- Gamification Educational Method, E-learning Educational Method
- Where
- Taiwan
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Taiwan Municipal An-Nan Hospital-China Medical University
Anaesthesia, Toxicity
Sensitivity of ECG on Detection of Three Different Intravascular Applied Test Doses of Bupivacaine and Epinephrine
The purpose of this prospective randomised study is to investigate electrocardiographic alterations after intravascular injection of three different test solutions of bupivacaine and epinephrine in anaesthetised children up to 16…
- Trial name
- NCT01091766
- Testing
- intravenous injection of test solution
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Artificial Intelligence, Electrocardiogram
Artificial Intelligence-enabled ECG Detection of Congenital Heart Disease in Children: a Novel Diagnostic Tool
Congenital heart disease (CHD) is the most common congenital disease in children. The early detection, diagnosis and treatment of CHD in children is of great significance to improve the prognosis and reduce the mortality of…
- Conditions
- Artificial Intelligence, Electrocardiogram, Deep Learning, Congenital Heart Disease in Children
- Trial name
- AI-ECG-CHD (NCT06383546)
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Fetal Monitoring, Non-invasive
Intrapartum Non-invasive Electrophysiological Monitoring
Conventional cardiotocography (CTG) has been used extensively for more than 50 years to monitor the fetal condition during labour, but since the rate of operative deliveries keeps rising, its ability to improve neonatal outcomes…
- Conditions
- Fetal Monitoring, Non-invasive, Cardiotocography, Electrocardiography
- Trial name
- NIEM-II (NCT06135961)
- Testing
- eCTG monitoring with the NFMS
- Where
- Netherlands
- Volunteers
- 3,471 people, healthy volunteers welcome
- Sponsor
- Maxima Medical Center
Heart Failure, Arrhythmias, Cardiac
Evaluation of ECG Transmission and AI Models Using Apple Watch ECGs and Symptoms Data Collected Using a Mayo iPhone App
The purpose of the study is to determine if the Electrocardiograms (ECGs) and symptoms data obtained from an Apple Watch and transmitted to Mayo Clinic are of sufficient quality to guide a person's care.
- Conditions
- Heart Failure, Arrhythmias, Cardiac, Health Care Utilization
- Trial name
- NCT05324566
- Where
- United States
- Volunteers
- 4,163 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cardiac Arrhythmia, Cardiovascular Diseases
Autonomic Nerve Stimulation Using External Auditory Canal Electrodes
Purpose of the study This study aimed to investigate electrocardiogram measurement and subthreshold low-level autonomic nerve stimulation using external auditory canal electrodes among healthy adult participants Study design…
- Trial name
- NCT04884607
- Testing
- subthreshold low-level autonomic nerve stimulation using external auditory canal electrodes
- Where
- South Korea
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Electrocardiographic Signal Acquisition
Effects of Electrode Preparation on 12-Lead ECG R-Wave Amplitudes
This study evaluated whether different methods of preparing the skin before a standard 12-lead electrocardiogram (ECG) affect the recorded ECG wave amplitudes.
- Trial name
- NCT07787104
- Testing
- Electrode Preparation
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Heart Failure
Home-based Outpatient Multicenter Evaluation Using Electrocardiogram (HOME-ECG)
This prospective multicenter observational study will validate the accuracy of a previously developed artificial intelligence-enabled single-lead electrocardiogram (AI-ECG) model for identifying low ejection fraction and other…
- Trial name
- HOME-ECG (NCT07488052)
- Testing
- Single-Lead ECG Acquisition [Apple Watch and QOCA ECG102D]
- Where
- Taiwan
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Defense Medical Center, Taiwan
Safety, Peripheral Neuropathy
Xanamem™ in Healthy Elderly Subjects
Xanamem™ is being developed as a potential drug for Alzheimer's disease. This study drug has been designed to change the cortisol levels in the brain. Cortisol is a naturally occurring hormone in the body.
- Conditions
- Safety, Peripheral Neuropathy, Cortisol, Central Nervous System
- Trial name
- XanaHES (NCT03830762)
- Testing
- Xanamem
- Where
- Australia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Actinogen Medical
Chest Pain, Electrocardiography
Timely Acquirement of 12-lead ECG Using Patchy-type Wireless Device Among Patient With Chest Pain
In this study, the investigators compare timely acquirement of 12-lead ECG using patchy-type wireless versus using standard 12-lead ECG system among patient with chest pain in ED.
- Trial name
- NCT04048733
- Testing
- patchy-type wireless 12-lead ECG
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Infections, Respiratory Tract
Placebo and Moxifloxacin Controlled Cardiac Conduction Study of GSK2140944 in Healthy Volunteers
This is Phase I, 4-period, randomized, active-and placebo-controlled, double-blind crossover, single-dose study to evaluate the effects of a therapeutic (1000 milligram [mg]) and supratherapeutic (1800 mg) dose of GSK2140944 with…
- Trial name
- NCT02257398
- Testing
- GSK2140944, Moxifloxacin
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cardiovascular Diseases, Cardiovascular Diseases Risk
Cor360: Clinician-Facing Broad-Spectrum Cardiac Phenotyping and Risk Assessment Using COR® Wearable ECG to Inform Outcomes-Oriented Care Pathways
Cor360 is an observational study evaluating whether extended wearable electrocardiogram (ECG) data can support broad-spectrum cardiac phenotyping and risk assessment beyond conventional single-purpose ambulatory rhythm…
- Conditions
- Cardiovascular Diseases, Cardiovascular Diseases Risk, Cardiac Conduction System Disease, Bundle/Fascicular Abnormalities
- Trial name
- Cor360 (NCT07775976)
- Testing
- COR Wearable ECG Monitoring, Cor360 Clinician-Facing Decision-Aid Reporting
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peerbridge Health, Inc