Clinical trials: Electrodes, Implanted
Brain Lesion, Head Trauma
Feasibility Study of Cortical Recording Depolarizations in Brain-injured Patients, and Their Use as Biomarkers of New Lesions.
The progression of brain lesions after severe head trauma or subarachnoid hemorrhage results from extra cranial aggression which is well controlled in intensive care and intracranial aggression which is less well known and…
- Conditions
- Brain Lesion, Head Trauma, Subarachnoid Hemorrhage
- Trial name
- SD-ICU (NCT04585503)
- Testing
- Electrode implantation
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Hearing Loss, Cochlear Implantation
Same-Day Cochlear Implant Activation (SDA-CI)
This randomized controlled study investigates whether activating a cochlear implant on the day of surgery (same-day activation) leads to faster stabilization of cochlear implant programming compared with the current standard…
- Trial name
- SDA-CI (NCT07681830)
- Testing
- Same-Day Cochlear Implant Activation, Standard Day-14 Cochlear Implant Activation
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Cochlear Hearing Loss
Safety and Performance of HiRes Ultra/Ultra 3D Cl Mid-Scala Electrodes in Adults With Severe-to-profound Hearing Loss
This is a prospective study designed to evaluate the safety and performance of the HiRes Ultra Cl HiFocus MS Electrode and HiRes Ultra 3D Cl HiFocus MS Electrode (Ultra X) under normal conditions of use as it is approved for this…
- Trial name
- NCT04610112
- Testing
- Cochlear implantation
- Where
- 3 sites in Germany
- Volunteers
- 30 people
- Sponsor
- Advanced Bionics AG
Inner Ear Malformations
A New Cochlear Implant Electrode For Inner Ear Malformations
The custom made device was produced by Med-El Company. It has a "cork" like stopper instead of the usual silicon ring to prevent gusher. There are two types of electrodes consisting of different length.
- Trial name
- NCT02011867
- Testing
- Cork Electrode
- Volunteers
- 50 people
- Sponsor
- Hacettepe University
Medication Refractory Epilepsy Patients With Electrodes Already Implanted Based on Clinical Criteria for Standard Monitoring
Model-based Electrical Brain Stimulation
Neuropsychiatric disorders are a leading cause of disability worldwide with depressive disorders being one of the most disabling among them.
- Trial name
- NCT05327387
- Testing
- model-based electrical brain stimulation
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- University of Southern California
Sudden Cardiac Death, Implantable Defibrillator
SCREENING FOR THE IMPLANTATION OF A SUBCUTANEOUS IMPLANTABLE AUTOMATIC DEFIBRILLATOR
S-ICD (subcutaneous implantable cardioverter-defibrillator) screening failure occurs in about 10% of cases. Predictors of screening failure are not yet well determined.
- Trial name
- SIS (NCT04101253)
- Testing
- new screening procedure with small variations in electrode positioning
- Where
- 16 sites in France
- Volunteers
- 480 people
- Sponsor
- Centre Hospitalier de PAU
Hearing Loss
Safety and Efficacy of a Drug Eluting Slim Modiolar Electrode Array
This clinical study will test a new type of cochlear implant known as CI632D. This experimental cochlear implant has been designed to slowly release a drug called dexamethasone.
- Trial name
- DEE-REX (NCT06598059)
- Testing
- Cochlear implant, Dexamethasone
- Where
- 11 sites in United States
- Volunteers
- 56 people
- Sponsor
- Cochlear
Atrial Fibrillation
Sensing Atrial High Rate Episodes With Implantable Cardioverter-Defibrillators Trial (The SENSE Trial)
The primary aim of the "Sensing Atrial High Rate Episodes with DX System in Implantable Cardioverter Defibrillators Trial" (SENSE Trial) is to assess the efficacy of a implantable cardioverter-defibrillator (ICD) lead with…
- Trial name
- SENSE (NCT02186704)
- Testing
- ICD with DX system
- Where
- 8 sites in United States
- Volunteers
- 450 people
- Sponsor
- Weill Medical College of Cornell University
Hearing Loss, Ear Diseases
Benefits of the HiResolution Bionic Ear System in Adults With Asymmetric Hearing Loss
The purpose of this feasibility study is to evaluate the benefit of unilateral implantation in adults who have severe to profound sensorineural hearing loss in one ear, and up to moderate sensorineural hearing loss in the other…
- Conditions
- Hearing Loss, Ear Diseases, Hearing Disorders, Otorhinolaryngologic Diseases
- Trial name
- NCT02811549
- Testing
- HiResolution Bionic Cochlear Implant
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Advanced Bionics
Sensorineural Hearing Loss, Bilateral
Study of a Minimally Invasive Cochlear Access for Cochlear Implantation Via a Robotic Procedure
The objectives of this study are to explore the efficacy and safety of a robotic procedure for a minimally invasive cochlear implantation.
- Trial name
- NCT04777565
- Testing
- Robotic surgery
- Where
- France
- Volunteers
- 10 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Hearing Loss
A Computational Approach to Optimal Deactivation of Cochlear Implant Electrodes
The goal of the present study is to use computationally driven models of speech understanding in cochlear implant (CI) users to guide the search for which combination of active electrodes can yield the best speech understanding…
- Trial name
- NCT05219474
- Testing
- Cochlear implant Computer Model Implementation
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Hearing Loss, Sensorineural
Investigating Stimulation Parameter and Electrode Mode Changes on Speech Perception in Experienced Adult Cochlear Implant Recipients
This study aims to investigate the effect of stimulation parameters and different electrode modes on speech perception in adult cochlear implant recipients.
- Trial name
- DUAL (NCT06298396)
- Testing
- Program using default MAP, Program using low-power 1 (LP1) MAP, Program using low-power 2 (LP2) MAP
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- Cochlear
Deafness
Perceptual Consequences of Cochlear Implant Electrode-neuron Interfaces
Despite the success of cochlear implants, devices surgically placed in the inner ears of patients with severe hearing loss, there remains substantial variability in the overall speech perception outcomes for the children and…
- Trial name
- NCT05867173
- Testing
- Experimental Speech Processing Strategy
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Chronic Pain, Hypertension
Epidural Spinal Cord Stimulation for Hypertension in Patients With Neuropathic Pain
The purpose of the ESCAPE Study is to determine the extent to which epidural spinal cord stimulation (SCS) reduces arterial blood pressure (BP) in patients which chronic low back pain and hypertension.
- Conditions
- Chronic Pain, Hypertension, Implanted Stimulation Electrodes
- Trial name
- ESCAPE (NCT04598035)
- Testing
- Diagnostic Tests
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- University of Kansas Medical Center
Cochlear Implantation, Robotics
Robotic-Assisted Versus Manual Electrode Array Insertion
Robotics-assisted electrode insertion overcomes many surgeon-related kinetic limitations such as insertion speed, tremor, drift, and lack of accurate force control.
- Trial name
- NCT06951594
- Testing
- Robotic
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Bruce J Gantz
Cochlear Implant
Subjective and Objective Results With CI Electrode Types
Background The authors' aim was to compare the influence of various electrode designs on selected objective and subjective clinical outcomes for cochlear implant recipients using the same model of receiver-stimulator, Cochlear™…
- Trial name
- NCT03515473
- Testing
- cochlear implant
- Where
- Hungary
- Volunteers
- 139 people
- Sponsor
- Szeged University
Hearing Loss, Sensorineural, Sensorineural Hearing Loss
Dexamethasone-Eluting Cochlear Implant Electrode
A newly developed MED-EL Cochlear Implant incorporates the anti-inflammatory agent dexamethasone (DEX) into the electrode array.
- Trial name
- CIDEX (NCT04450290)
- Testing
- CIDEXEL implant
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Low Intensity Focussed Ultrasound, Electrodes, Implanted
Mapping LIFU Responses Using iEEG Recordings
The current study presents a unique opportunity to measure the immediate neural responses to brief, non-therapeutic transcranial low-intensity focused ultrasound (LIFU) pulses using intracranial electrodes.
- Trial name
- NCT07518927
- Testing
- Low Intensity Focused Ultrasound
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pennsylvania
Hearing Loss, Cochlear Implant
Cochlear Trauma, Functional and Structural Preservation in Cochlear Implant Surgery
Prospective 2-arm cohort consisting of a preoperative visit and visits at the time of implantation (Day 0) and follow-up in patients for whom their treating physician indicated a perimodiolar or straight cochlear implant.
- Conditions
- Hearing Loss, Cochlear Implant, Cochlear Microphonics, Electrocochleography
- Trial name
- NCT05079867
- Testing
- Cochlear implantation
- Where
- Argentina
- Volunteers
- 40 people
- Sponsor
- Hospital Italiano de Buenos Aires
Defibrillators, Implantable, Electrodes, Implanted
Slew Rate As a Predictor for Optimal Lead Fixation
The goal of this observational study is to identify the most reliable electrical parameter measured at the time of implantation that can predict optimal lead fixation and long-term lead performance in patients undergoing…
- Conditions
- Defibrillators, Implantable, Electrodes, Implanted, Pacemaker, Artificial, Predictive Value of Tests
- Trial name
- SLEW REGISTRY (NCT06842940)
- Where
- Italy
- Volunteers
- 516 people
- Sponsor
- Paolo Pastori, MD