Clinical trials: Electrophysiology
Pain, Acute
Impact of Virtual Reality in Cardiac Electrophysiology
Pain during pacemaker or defibrillator implantation can increase patient discomfort, anxiety, and the need for deeper sedation. Using virtual reality (VR) as a non-pharmacological distraction tool may help reduce perceived pain…
- Trial name
- NCT07009951
- Testing
- Virtual reality
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Calabria
Neurological Disorder
Chart Review: Central Motor Conduction Time in Neurological Disorders
Background: TMS stands for transcranial magnetic stimulation. It is a non-invasive way to stimulate the brain. It helps researchers study the nervous system. TMS can assess central motor conduction time (CMCT).
- Trial name
- NCT03300856
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Posttraumatic Stress Disorder, Major Depressive Disorder
Predicting SSRI Efficacy in Veterans With PTSD
This is a research study to examine the effectiveness of a brief screening method that may predict which people with posttraumatic stress disorder (PTSD) or depression are most likely to show a positive response to selective…
- Trial name
- SSRI (NCT04183205)
- Testing
- LDAEP, sertraline
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- VA Office of Research and Development
Epilepsy
Human Intracranial Electrophysiology
This study will enroll patients with epilepsy who are being evaluated for epilepsy surgery and have electrodes implanted in the brain and/or have electrodes on the scalp.
- Trial name
- NCT05529264
- Testing
- Memory Tasks, Attention/arousal tasks, Language tasks
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Respiratory Depression, Blood Pressure
Cardiopulmonary Responses to Exposure to Ozone and Diesel Exhaust
The US EPA Clean Air Multiyear research program is moving toward a multi-pollutant approach to the assessment of air pollution in response to recommendations by the NRC 2004 and the BOSC in 2005.
- Trial name
- DEPOZ (NCT01874834)
- Testing
- ozone
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Depression
rTMS and Cognitive Training in Youth Depression
Youth depression is a highly prevalent disorder with tremendous personal and societal costs. Guideline supported treatments are limited in efficacy and associated with side effects.
- Trial name
- NCT03708172
- Testing
- Repetitive Transcranial Magnetic Stimulation, Cognitive Training
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre for Addiction and Mental Health
Stress, Psychological, Stress, Physiological
Stress Inoculation Through Virtual Reality in the Pediatric Electrophysiology Laboratory
The goal of this study is to assess the utility of virtual reality technology to aid in the mental health of patients with cardiac disease, specifically looking at decreasing anxiety and perceptions of pain from stressful…
- Conditions
- Stress, Psychological, Stress, Physiological, Anxiety, Pain Perception
- Trial name
- NCT02949401
- Testing
- Use of Virtual Reality App
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University
Intraoperative Awareness
Measurement of Bispectral Index and Awareness in Patients Undergoing Electrophysiology Studies With Isoproterenol
Isoproterenol is used as a cardiac stimulant in electrophysiology studies (EP). Preliminary data suggests that administration of isoproterenol increases the Bispectral index (BIS).
- Trial name
- NCT01377636
- Testing
- Isoproterenol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Neurocardiogenic Syncope, Vasovagal Syncope
Cardioneuroablation for Neurocardiogenic Syncope
The purpose of this study is to evaluate the effectiveness of cardioneuroablation for the treatment of neurocardiogenic syncope (NCS), also known as "vaso-vagal" syncope.
- Trial name
- Ablate-NCS (NCT02009982)
- Testing
- Cardioneuroablation, Biosense Webster Navistar ThermoCool Diagnostic/Ablation Deflectable Tip Catheter
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- David B. De Lurgio
Electrophysiology Study, Ablation
Torque Device Evaluation
This study will evaluate the safety and efficacy of a novel catheter torque device after the completion of a clinically-indicated electrophysiology study and/or ablation procedure in a pediatric patient.
- Trial name
- NCT07094256
- Testing
- Peritorq
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- University of Minnesota
Auditory Perceptual Impairment, Aging
Using Nicotine to Reverse Age-related Auditory Processing Deficits
The present study will evaluate the effects of both aging and nicotine on psychophysical tasks and electrophysiological measures.
- Trial name
- Nicotine (NCT04971954)
- Testing
- Nicotine gum
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Non Specific Chronic Low Back Pain
Clinical Electrophysiology Assessment for Low Back Pain
Non specific chronic low back pain (LBP) is a debilitating disorder characterized by tremendous personal and socioeconomic impact, with long-term sick leave, low quality of life, and very high financial costs.
- Trial name
- LBP (NCT03511404)
- Testing
- physiotherapy rehabilitation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
SARS-CoV 2
Exploring Brain Damages After COVID-19 Infection
Although direct evidence is currently lacking, the high identity between SARS-CoV-1 and SARS-CoV-2 suggests, that the latter viral strain could also infect the Central Nervous System (CNS).
- Trial name
- BRAINCOV (NCT04405986)
- Testing
- Auditory Evoked Potentials (AEP), Blink and Masseter Inhibitory Reflex
- Where
- France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Bordeaux
Focal Epilepsy, Temporal Lobe Epilepsy
Spatial Scene Recognition Memory in Epilepsy Surgery
This study investigates the anatomical and physiological basis of spatial scene recognition memory in patients with temporal lobe epilepsy and temporal lobe lesions.
- Conditions
- Focal Epilepsy, Temporal Lobe Epilepsy, Medically Refractory Epilepsy, Memory Disorders
- Trial name
- NCT07580183
- Testing
- Virtual Tour Recognition Memory Task, Intracranial EEG Recording with Research Electrodes (Aim III only), MRI Neuroimaging and Neuropsychological Assessment (Aim I)
- Where
- 2 sites in United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Tourette Syndrome, Deep Brain Stimulation
Multitarget Stereotactic Electrophysiological Recording and Stimulation for Tourette Syndrome
The goal of this clinical trial is to investigate the neural mechanisms underlying Tourette syndrome (TS) and see if personalized deep brain stimulation (DBS) can help reduce tics in TS patients and improve related issues like…
- Trial name
- MASTERS-TS (NCT06889480)
- Testing
- New Target DBS, CM-DBS
- Where
- China
- Volunteers
- 5 people
- Sponsor
- Beijing Tiantan Hospital
Atrial Fibrillation, Hypertension
Irbesartan for the Prevention of Atrial Arrhythmias and Cardiac Electrical Remodeling in Patients With Hypertension and Permanent Pacemakers
The purpose of this study is to determine whether irbesartan will reduce the rate of recurrent atrial high rate episodes and the development of clinical sustained atrial fibrillation in patients with hypertension and permanent…
- Trial name
- NCT00225667
- Testing
- Irbesartan
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Connolly, Stuart, M.D.
Premature Ejaculation
Research and Clinical Value of New Classification for Premature Ejaculation: Multi-Center Research
An observational study on the effect of new classification for premature ejaculation.
- Trial name
- NCT02572037
- Where
- 6 sites in China
- Volunteers
- 568 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Tensiomyography, Gastrocnemius Muscle Assessment
Tensiomyography of Gastrocnemius in Lumbar Radiculopathy
This cross-sectional study aims to evaluate the neuromuscular characteristics of the gastrocnemius muscles in individuals with chronic lumbar radiculopathy using tensiomyography (TMG).
- Conditions
- Tensiomyography, Gastrocnemius Muscle Assessment, Chronic Lumbar Radiculopathy
- Trial name
- TMGGLR (NCT06767280)
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Cairo University
Refractory Epilepsy, Neuromodulation
Characterising the Network-Specific Effects of Piriform Cortex Stimulation Via SEEG
The prospective study aims to characterize the network-specific modulatory effects of piriform cortex stimulation in patients undergoing stereotactic EEG for drug-resistant epilepsy.
- Trial name
- NCT07305311
- Testing
- SEEG recordings and SPES
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xuanwu Hospital, Beijing
Congenital Cataract
Electrophysiology in Congenital Cataract After Lensectomy and Anterior
In this prospective study , a cohort of 91 eyes with congenital cataract and 25 eyes normal eyes from Wenzhou medical university was erolled.91 eyes with congenital cataract was after lensectomy and anterior vitrectomy as test…
- Trial name
- NCT04427748
- Where
- China
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University