Clinical trials: Electrophysiology
Major Depressive Disorder
Electrophysiologic Parameters and Biomarkers Predicting Treatment Response in Patients With Major Depressive Disorder
To explore electrophysiologic parameters and biomarkers predicting treatment response of patients with major depressive disorder To explore electrophysiologic parameters and biomarkers predicting suicide risk of patients with…
- Trial name
- NCT01997580
- Testing
- escitalopram
- Where
- South Korea
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Electrical Stimulation of Nerves Produces Muscle Reflexes
Effects of Uremia on Brachial Plexus Electrophysiology and Brachial Plexus Block
As a late stage of renal failure, uremia not only leads to severe impairment of renal function in patients, but also often leads to a variety of complications, among which multiple peripheral neuropathy is particularly common.
- Trial name
- NCT06931756
- Testing
- Neural Stimulator
- Volunteers
- 60 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Tensiomyography, Gastrocnemius Muscle Assessment
Tensiomyography of Gastrocnemius in Lumbar Radiculopathy
This cross-sectional study aims to evaluate the neuromuscular characteristics of the gastrocnemius muscles in individuals with chronic lumbar radiculopathy using tensiomyography (TMG).
- Conditions
- Tensiomyography, Gastrocnemius Muscle Assessment, Chronic Lumbar Radiculopathy
- Trial name
- TMGGLR (NCT06767280)
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Cairo University
Ventricular Tachycardia
Anesthetic Management in Patients Undergoing Epicardial Ablation
The study is a retrospective study and is descriptive in nature. In this study, the investigators aimed to emphasize the importance of anesthesia management by cardiac risk assessment of patients undergoing epicardial ablation…
- Trial name
- NCT06538987
- Testing
- percutaneous epicardial ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Prodromal Schizophrenia, Psychotic Episode
REtinal and VIsual Cortical Response in Early PSYchosis
The purpose of the REVIPSY study is to measure retinal and the visual cortical electrophysiological responses in situations at risk of psychosis in patients who have experienced a first psychotic episode.
- Conditions
- Prodromal Schizophrenia, Psychotic Episode, Prodromal Symptoms, Healthy Controls
- Trial name
- REVIPSY (NCT05167396)
- Testing
- Retinaute (BioSerenity), EEG Headset 64 electrodes (BioSemi), MonPackOne (Metrovision)
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Centre Psychothérapique de Nancy
Cardiac Arrhythmia
Measuring Hydration Levels of Healthy and Heart Failure Patients Before, During, and After an Electrophysiology (EP) Procedure
Subjects will be consented to wear the AleriTM sensor prior to, during, and after an Electrophysiology Procedure. During this time, the system will measure the following parameters from subjects: HR, temperature, saline…
- Trial name
- NCT04609683
- Testing
- AleriTM sensors
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- NYU Langone Health
Heart Failure
Optimization of Cardiac Resynchronization Therapy by Non-Invasive Imaging of Cardiac Electrophysiology
The principal aim is to analyze total left and right ventricular activation time in different CRT device programming algorithms (SyncAV) measured by non-invasive electrophysiology
- Trial name
- NICE CRT (NCT04662970)
- Testing
- Device programming
- Where
- Austria
- Volunteers
- 25 people
- Sponsor
- Medical University Innsbruck
Pompe Disease
Phrenic Nerve and Diaphragm Electrophysiology in Pompe Disease
Pompe disease is traditionally considered a lysosomal myopathy. However, increasing experimental and clinical evidence suggests involvement of the entire motor unit, including motor neurons, peripheral nerves, neuromuscular…
- Trial name
- NCT07664930
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Diaphragm Dysfunction
Ultrafast Ultrasound for the Functional Assessment of the Diaphragm
The aims of the current study are as follows: i) Investigate the relationships between indices derived from ultrafast ultrasound imaging and Pditw, ii) Investigate the relationships between indices derived from ultrafast…
- Trial name
- ECHOSTIM-EFR (NCT05265351)
- Testing
- Transdiaphragmatic pressure measurement, EMG
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Institut de Myologie, France
Cardiac Electrophysiology, Anesthesia
Prophylactic Non-invasive Ventilation During Surgical Procedure in Rhythmology
Acute respiratory failure is frequent during rhythmology procedure under light sedation in high risks selected patients. Non invasive ventilation (NIV) is recommended for acute cardiogenic pulmonary oedema and sleep apnea.
- Conditions
- Cardiac Electrophysiology, Anesthesia, Acute Respiratory Failure
- Trial name
- VNI-RYTHMO (NCT02779998)
- Testing
- non invasive ventilation, Standard oxygen therapy with facial mask
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Grenoble
Ventricular Tachycardia
Stereotaxis Study To Obliterate Persistent Ventricular Tachycardia
This is a prospective, non-randomized, multi-center clinical case series evaluating the outcomes of the magnetic navigation system in ventricular tachycardia (VT) cases.
- Trial name
- STOP-VT (NCT00851279)
- Testing
- Magnetic irrigated ablation catheter
- Where
- 4 sites in United States, Czechia and 1 more
- Volunteers
- 53 people
- Sponsor
- Stereotaxis
Neuromuscular Disease, Motor Neuron Disease
Electrical Impedance Myography: Natural History Studies inNeuromuscular Disorders and Healthy Volunteers
Background: Electrical impedance myography (EIM) is a new technique being studied to see if it is helpful in evaluating muscle disorders and nerve disorders.
- Conditions
- Neuromuscular Disease, Motor Neuron Disease, Inherited Neuromuscular Conditions, Inherited Neuropathies
- Trial name
- NCT01900132
- Testing
- EIM testing, Nerve & muscle ultrasonography, Nerve conduction studies
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Amyotrophic Lateral Sclerosis
Electrophysiology and Ultrasound of Respiratory Muscles and Respective Nerves to Predict Respiratory Insufficiency in ALS
Respiratory insufficiency is a common complication in amyotrophic lateral sclerosis (ALS). Survival can be prolonged with noninvasive ventilation (NIV).
- Trial name
- NCT06841341
- Testing
- electromyography, ultrasonography, Arterial blood gas analysis
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Jagiellonian University
Stroke
EEG Changes and DNA Markers Related to taVNS in Stroke Patients: a Preliminary Study
In the United States, more than 795,000 people have a stroke every year. Motor impairment after a stroke is common and can be debilitating.
- Trial name
- StrokeVNS (NCT06226493)
- Testing
- Transcutaneous vagus nerve stimulation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Addiction, Substance Use Disorder (SUD)
HABITS Study (Helping Addiction by Individualized Therapeutic Stimulation): Pilot Trial of Deep Brain Stimulation Guided By Stereoelectroencephalography for Treatment-Refractory Substance Use Disorders
Substance use disorder (SUD) or addiction to drugs/alcohol is a devastating disease. Over 40,000 overdose deaths have happened in Canada since 2016, 1 in 5 Canadians will have a SUD, and 70% of those with SUD continue to relapse…
- Trial name
- HABITS (NCT06973512)
- Testing
- deep brain stimulation and stereoelectroencephalography
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Centre for Addiction and Mental Health
Parkinson's Disease (PD)
Electrophysiology-based DBS Programming for PD
Deep brain stimulation (DBS) effectively alleviates motor symptoms in Parkinson's disease (PD). However, current programming is manual and time-consuming.
- Trial name
- NCT07348705
- Testing
- Clinician-based DBS programming, Maximum Beta power-based DBS programming, Broad-band electrophysiology-based DBS programming
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida
ALS
Spinal Interneuron Excitability in ALS
Amyotrophic lateral sclerosis (ALS) is due to neurodegeneration of upper and lower motor neurons, leading to muscle atrophy, paralysis and death.
- Trial name
- SpineBioMark (NCT02429492)
- Testing
- Electrophysiology
- Where
- France
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Parkinson Disease
Combined Deep Brain Stimulation for Parkinson's Disease
Background: Deep brain stimulation (DBS) in the subthalamic nucleus (STN) is an approved treatment for Parkinson s disease. It stimulates a part of the brain that helps control symptoms like tremor, stiffness, and slow movements.
- Trial name
- NCT01485276
- Testing
- DBS Surgery
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cardiac Arrhythmia, Atrial Fibrillation
The Role of Right Atrial Ectopy Triggering Ganglionated Plexuses in AF
Atrial fibrillation (AF) is the most common rhythm disturbance of the heart. It can affect people of any age but usually happens as we get older. It can cause palpitations, breathlessness, lethargy, and fainting attacks.
- Trial name
- RGanglia-AF (NCT05539040)
- Testing
- Right Atrial ganglionated plexus ablation, Holter Monitor, Pulmonary vein isolation
- Where
- United Kingdom
- Volunteers
- 116 people
- Sponsor
- Imperial College London
Atrial Fibrillation, Atrial Fibrillation, Persistent
Ablation of Focal Activation in Atrial Fibrillation
Recurrent focal electrical activation (or ectopy) superseding sinus activation is the only mechanism proven to drive paroxysmal atrial fibrillation (AF).
- Conditions
- Atrial Fibrillation, Atrial Fibrillation, Persistent, Arrhythmia, Arrhythmias, Cardiac
- Trial name
- RETRO-AF (NCT06402617)
- Testing
- Pulmonary vein isolation, RETRO-Mapping without adjunctive ablation, Adjunctive ablation guided by RETRO-Mapping
- Where
- United Kingdom
- Volunteers
- 110 people
- Sponsor
- Imperial College London