Clinical trials: Electrophysiology Study
Arrythmia
Epicardial Access Study With Rook
The goal of this clinical trial is to test how how effective the Circa Scientific Rook® Epicardial Access Kit is at gaining guidewire access to the outside surface of the heart (epicardium).
- Trial name
- EASY-R (NCT06388629)
- Testing
- Rook Epicardial Access Kit
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- Circa Scientific, Inc.
Paroxysmal Atrial Fibrillation
Atrial Fibrillation Force Contact Ablation Study
This study will be divided into two phases. The purpose of the Phase I registry is to assess the current force being used for ablation of symptomatic paroxysmal AF in a wide range of operators in different Canadian centres with…
- Trial name
- CAFCAS (NCT01693107)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Cardiac Electrophysiology
Transvenous Lead Removal Post-Market Clinical Study
This prospective, multicenter, post-market clinical study was designed to evaluate the outcomes of lead extraction of cardiovascular implantable electronic devices (CIED) using Cook catheter and lead extraction devices for any…
- Trial name
- NCT03688412
- Testing
- Cook lead extraction devices
- Where
- 9 sites in United States, Germany and 2 more
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Cook Research Incorporated
Schizophrenia / Schizoaffective Disorder, Schizophrenia and Disorders With Psychotic Feature
Building a Computational Model of Auditory Hallucinations
Some people hear voices or sounds that other people cannot hear; these are called auditory hallucinations. The study aims to understand what is happening in the brain when this occurs and will use brain scans to learn more.
- Conditions
- Schizophrenia / Schizoaffective Disorder, Schizophrenia and Disorders With Psychotic Feature, Psychosis, SCHIZOPHRENIA 1 (Disorder)
- Trial name
- CLARITY WP1 (NCT07820553)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- King's College London
Cardiac Catheterization, Electrophysiology Procedure
Post Anesthesia Care Unit (PACU) Weighted Blanket Study
This study is being conducted to evaluate the safety and efficacy of weighted blankets to reduce agitation in patients in the post-procedural phase after cardiac catheterization and electrophysiology procedures in the post…
- Conditions
- Cardiac Catheterization, Electrophysiology Procedure, Pediatric Cardiology
- Trial name
- NCT05632640
- Testing
- Standard of Care, Weighted blanket
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Michigan
Atrial Fibrillation
Ultrasound-Based Renal Sympathetic Denervation as Adjunctive Upstream Therapy During Atrial Fibrillation Ablation
The purpose of the ULTRA-HFIB Pilot is to determine the role of adjunctive renal denervation (RDN) in the prevention of Atrial Fibrillation (AF) recurrence in patients scheduled for an AF ablation procedure.
- Trial name
- ULTRA-HFIB (NCT04182620)
- Testing
- renal denervation, Catheter ablation
- Where
- 13 sites in United States
- Volunteers
- 160 people
- Sponsor
- Vivek Reddy
Scleroderma, Hand Functionality
Ultrasound and Electrophysiology Study of Hand in Systemic Sclerosis Patients and Contributors of Hand Dysfunction
The goal of this research is to assess quality of life and hand function in systemic sclerosis patients via specific questionnaires, and to determine the main contributors to hand dysfunction via a thorough hand ultrasound study…
- Conditions
- Scleroderma, Hand Functionality, Quality of Life (QOL)
- Trial name
- NCT06776575
- Volunteers
- 45 people
- Sponsor
- Assiut University
Ventricular Tachycardia
Anti-arrhythmic Medication v. MRI-Merge Ablation in the Treatment of Ventricular Tachycardia
Ventricular tachycardia (VT) is a morbid arrhythmia responsible for many sudden deaths and ICD shocks. Despite much progress in the treatment of arrhythmia, VT remains a therapeutic challenge.
- Trial name
- NCT00721032
- Testing
- MRI guided VT ablation, Increased dose of amiodarone
- Where
- United States
- Sponsor
- Johns Hopkins University
Healthy Lifestyle
Improving Wellbeing Through the Brain-Gut-Microbiota Axis
Well-being is a state defined as the optimal psychological functioning and the experience associated with it, integrating physical and subjective factors.
- Trial name
- IBMA (NCT04823533)
- Where
- Chile
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
ALS
Spinal Interneuron Excitability in ALS
Amyotrophic lateral sclerosis (ALS) is due to neurodegeneration of upper and lower motor neurons, leading to muscle atrophy, paralysis and death.
- Trial name
- SpineBioMark (NCT02429492)
- Testing
- Electrophysiology
- Where
- France
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Guillain-Barré Syndrome, Miller Fisher Syndrome
International Guillain-Barré Syndrome Outcome Study
International GBS Outcome Study (IGOS) is a study conducted by the members of the Inflammatory Neuropathy Consortium (INC) and Peripheral Nerve Society (PNS) on disease course and outcome in Guillain-Barré syndrome (GBS).
- Trial name
- IGOS (NCT01582763)
- Where
- 138 sites in United States, Argentina and 19 more
- Volunteers
- 2,000 people
- Sponsor
- Erasmus Medical Center
Cardiac Arrhythmia
Sedation Regimen in Patients Undergoing Cardiac Electrophysiology Study and Ablation : a Comparison Between Dexmedetomidine-remifentanil and Midazolam-remifentanil Combinations
Cardiac ablation is an invasive procedure requiring anesthetic support for immobility and analgesia. Benzodiazepines and opioids are the most commonly used agents, while they are associated with respiratory depression and…
- Trial name
- NCT01652586
- Testing
- dexmedetomidine-remifentanil, midazolam-remifentanil
- Volunteers
- 90 people
- Sponsor
- Yonsei University
Coma, Disorder of Consciousness
Development of a Point of Care System for Automated Coma Prognosis
Electroencephalogram/event-related potentials (EEG/ERP) data will be collected from 50 participants in coma or other disorder of consciousness (DOC; i.e., Unresponsive Wakefulness Syndrome [UWS] or Minimally Conscious State…
- Conditions
- Coma, Disorder of Consciousness, Minimally Conscious State, Vegetative State
- Trial name
- NCT03826407
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- McMaster University
Cardiac Arrhythmia
The Objective of This Multicentre Study is to Collect Operative Data on the Related Clinical Functional Outcomes and Complications and of Market Approved Alcis Electrophysiology Catheters to Demonstrate Safety and Performance of These Devices in a Real-world Setting
The objective of this multicentre study is to collect operative data on the related clinical functional outcomes and complications and of market approved Alcis electrophysiology catheters to demonstrate safety and performance of…
- Trial name
- NCT05314218
- Testing
- Electrophysiology catheters and cables
- Where
- 2 sites in France
- Volunteers
- 168 people
- Sponsor
- Alcis
PVC - Premature Ventricular Complex, Ablation
Virtual Reality in Electrophysiology Laboratory (EP)
The purpose of this study is to evaluate the use of virtual reality (VR) technology as adjunct to routine anesthesia care for patients undergoing electrophysiology (EP) procedures.
- Trial name
- NCT04893278
- Testing
- Virtual reality
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Stroke
EEG Changes and DNA Markers Related to taVNS in Stroke Patients: a Preliminary Study
In the United States, more than 795,000 people have a stroke every year. Motor impairment after a stroke is common and can be debilitating.
- Trial name
- StrokeVNS (NCT06226493)
- Testing
- Transcutaneous vagus nerve stimulation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Pre-excitation Syndromes, Paroxysmal Tachycardia
Routine Mini-invasive Electrophysiology Study for Patients Feeling Tachycardia, With a Negative Holter ECG
Patients complaining of tachycardia but with a negative Holter ECG, are for a limited time period offered a simplified electrophysiological(EP) examination.
- Conditions
- Pre-excitation Syndromes, Paroxysmal Tachycardia, Atrial Fibrillation, Atrial Flutter
- Trial name
- NCT00251121
- Testing
- Mini-invasive electrophysiological study, Atrial pacing
- Where
- Norway
- Volunteers
- 51 people
- Sponsor
- Sykehuset Telemark
Electrical Stimulation of Nerves Produces Muscle Reflexes
Effects of Uremia on Brachial Plexus Electrophysiology and Brachial Plexus Block
As a late stage of renal failure, uremia not only leads to severe impairment of renal function in patients, but also often leads to a variety of complications, among which multiple peripheral neuropathy is particularly common.
- Trial name
- NCT06931756
- Testing
- Neural Stimulator
- Volunteers
- 60 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Stroke, Hemiplegia
Relationship Between Clinical Status and Nerve Conduction Test Findings in Patients With Unilateral Hemiplegia
Stroke-related hemiplegia may be accompanied by peripheral nerve conduction abnormalities, which may contribute to motor impairment and functional limitations.
- Conditions
- Stroke, Hemiplegia, Intracranial Hemorrhage, Spontaneous
- Trial name
- NCT07685691
- Testing
- Nerve Conduction Study
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Baskent University
Atypical Atrial Flutter, Atrial Flutter
Pulsed-Field Ablation for Recurrent Atypical Atrial Flutter
Recurrent atypical atrial flutter (AFL) after prior atrial fibrillation or flutter ablation remains challenging to treat, and conventional radiofrequency ablation may be limited by incomplete lesion formation and risk of…
- Trial name
- NCT07362134
- Testing
- Point-by-point pulsed-field catheter ablation
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan