Clinical trials: Elevated Blood Sugar
Hyperglycaemia
Effects of Polyphenols Found in Pomegranate and Olives Food Supplements on Postprandial Blood Glucose in Vivo.
Consumption of carbohydrate containing foods or sugary drinks brings about changes to the blood glucose levels. After a meal or drink, blood glucose rises until it reaches a peak concentration usually after 30 minutes.
- Trial name
- NCT02486978
- Testing
- Control (109 g white bread), Dose 1, Dose 2
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Pre-diabetes, Type 2 Diabetes
Effect of Exenatide, Sitagliptin or Glimepiride on Functional ß -Cell Mass
This study evaluates exenatide, sitagliptin, and glimepiride for the treatment of high blood sugar in patients with impaired fasting glucose or early type 2 diabetes.
- Trial name
- NCT00775684
- Testing
- Exenatide, Sitagliptin, Glimepiride
- Where
- 3 sites in United States
- Volunteers
- 47 people
- Sponsor
- University of Pennsylvania
Body Composition, Beneficial, Paresis
Meal Patterning on Weight Loss With Changes to Body Comp, Muscle and Metabolic Health
About two-thirds of adults in the United States are overweight or obese with likely adverse health consequences. A Moderate weight loss by dieting and exercise is recommended to improve health.
- Conditions
- Body Composition, Beneficial, Paresis, Impaired Glucose Tolerance
- Trial name
- S38 (NCT02066948)
- Testing
- wt loss, Meal Pattern, even
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Purdue University
Weight Loss, Pre Diabetes
Healthy Body Healthy Souls in the Marshallese Population
The primary aim is to pilot test a weight-loss intervention for Marshallese adults, referred to throughout as Healthy Bodies Healthy Souls (HBHS).
- Conditions
- Weight Loss, Pre Diabetes, Overweight and Obesity
- Trial name
- NCT03377244
- Testing
- HBHS, HBHS Policy, WORD DPP
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Critical Illness, Hyperglycaemia
Intermittent Versus Continuous Glucose Monitoring in Intensive Care Unit
Glucose control is an important part of supportive care for critically ill patients. Achieving optimal glucose control in such situations is challenging due to frequent fluctuations in blood glucose levels.
- Conditions
- Critical Illness, Hyperglycaemia, Hypoglycaemia
- Trial name
- ICONS-ICU (NCT07088549)
- Testing
- Continuous glucose monitoring, Control Arm - standard of care
- Where
- Slovenia
- Volunteers
- 200 people
- Sponsor
- University Medical Centre Ljubljana
Metabolic Syndrome, Impaired Glucose Tolerance
Prevention of Type 2 Diabetes Mellitus by L-Arginine in Patients With Metabolic Syndrome
Aim The principal objective of this project is: To evaluate the efficacy of long term (18 months) L-Arginine therapy in preventing or delaying clinical onset of type 2 diabetes mellitus in subjects with impaired glucose tolerance…
- Conditions
- Metabolic Syndrome, Impaired Glucose Tolerance, Insulin Resistance, Endothelial Dysfunction
- Trial name
- L-arginine (NCT00917449)
- Testing
- L-arginine
- Where
- Italy
- Volunteers
- 142 people
- Sponsor
- IRCCS San Raffaele
Gestational Diabetes Mellitus in Pregnancy, Cognitive Impairment
Gestational Diabetes Mother-infant Cohort
The bi-directional dynamic cohort study is to learn about the effects of prenatal exposure to high blood glucose levels and postnatal nurturing environment factors on delayed language development in children.
- Conditions
- Gestational Diabetes Mellitus in Pregnancy, Cognitive Impairment, Cohort Study
- Trial name
- NCT06021691
- Testing
- Acquired nurturing environment
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gansu Provincial Maternal and Child Health Care Hospital
Diabetes
Controlling Hyperglycemia Among Minority Population
The purpose of this study is to compare the efficacy of three approaches in diabetes management: (1) community health worker (CHW) education; (2) text messaging; and (3) usual hospital-based care.
- Trial name
- CHAMP (NCT02681718)
- Testing
- Community health worker education, Cell phone text messaging
- Where
- United States
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Sinai Health System
Diabete Mellitus, Pre-diabetes
Investigating the Syndrome Differentiation of Diabetic and Pre-diabetic Using Digitalized TCM Diagnostic Tools
The investigators aim to objectively identify the Traditional Chinese Medicine (TCM) syndrome differentiation of type II diabetic and prediabetic patients in Singapore through modern technologies thereby potentially increasing…
- Conditions
- Diabete Mellitus, Pre-diabetes, Healthy, Hypertension
- Trial name
- NCT05563090
- Testing
- Questionnaires+Tongue diagnosis+Pulse diagnosis
- Where
- Singapore
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Singapore Chung Hwa Medical Institution
Hyperglycemia, Aneurysmal Subarachnoid Hemorrhage
Admission HbA1C in Aneurysmal Subarachnoid Hemorrhage
In patients suffering from aneurysmal subarachnoid hemorrhage (aSAH), hyperglycemia is considered an adverse prognostic factor. Glycated hemoglobin (or HbA1c) can be measured to estimate the average plasma glucose concentration…
- Trial name
- NCT02081820
- Where
- Germany
- Volunteers
- 89 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Gestational Diabetes Mellitus, Pregnancy Outcome
GDM and Its Consequences in Mothers and Offsprings
Gestational diabetes mellitus (GDM) is one of the most common disorders which occured during pregnancy. GDM is not only associated with short-term maternal and fetal adverse outcomes, but also related to a wide range of long-term…
- Conditions
- Gestational Diabetes Mellitus, Pregnancy Outcome, Neurodevelopment, Immune Development
- Trial name
- GDMCMO (NCT04529889)
- Where
- China
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Impaired Glucose Tolerance, Diabetes
Progression to Impaired Glucose Tolerance and Type 2 Diabetes in the Korean People-based KNDP Study
Impaired glucose tolerance is a metabolic state between normal glucose homeostasis and diabetes. Previously, prospective studies have shown higher progression rates from IGT to diabetes in other country.
- Trial name
- NCT01034826
- Volunteers
- 500 people
- Sponsor
- Korea University Guro Hospital
Diabetes Mellitus, Type 2
Treatment of Type 2 Diabetes With Immunonutrients
The purpose of this research study is to determine if the nutrients arginine and fish oil will reverse or improve diabetes and to find out what additional good or bad effects a combination of arginine and fish oil may have.
- Trial name
- NCT02462863
- Testing
- Arginine and fish oil
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- The Christ Hospital
Metabolic Syndrome (MetS), Inflammation
Comparing a Healthy Beef-Centric Diet to a Healthy U.S.-Style Diet on Metabolic Health Outcomes in Pre-Diabetic Adults
This randomized study will be conducted to compare the effect of a healthy beef-centric diet to a healthy U.S.-style dietary pattern on inflammation and other metabolic health outcomes in a metabolic syndrome and/or pre-diabetic…
- Conditions
- Metabolic Syndrome (MetS), Inflammation, Pre-Diabetes
- Trial name
- NCT07269847
- Testing
- Healthy Beef-Centric Diet, Healthy U.S.-Style Dietary Pattern
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- National Cattlemen's Beef Association, a contractor to the Beef Checkoff
Prediabetic State
Rimonabant In Prediabetic Subjects To Delay Onset Of Type 2 Diabetes
Primary objective: To evaluate the effect of long-term administration of Rimonabant on the time of progression to type 2 diabetes in patients with prediabetes (i.e.
- Trial name
- RAPSODI (NCT00325650)
- Testing
- Rimonabant
- Where
- United States
- Volunteers
- 2,420 people
- Sponsor
- Sanofi
Pre-diabetes, Overweight
Genetic Counseling and Lifestyle Change for Diabetes Prevention
This study will examine the impact diabetes genetic counseling on patient motivation and disease prevention behaviors among subjects with pre-diabetes.
- Conditions
- Pre-diabetes, Overweight, Metabolic Syndrome
- Trial name
- GC/LC (NCT01034319)
- Testing
- Diabetes Genetic Counseling, No genetic counseling
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Massachusetts General Hospital
Lipid Profile
Hypoglycemic Potential of Garcinia Cambogia (Garcinia Gummi-gutta (L.) N.Robson) Rind Powder Among Pre-diebetic Obese Patients
Garcinia cambogia, rich in hydroxycitric acid (HCA), has been suggested to promote weight loss and improve metabolic parameters. Evidence regarding its efficacy in pre-diabetic obese adults remains limited.
- Trial name
- NCT07419074
- Testing
- Garcinia cambogia rind powder
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Hyperglycemia, Hyperglycemia, Postprandial
NUTRACORE, Glycaemic Index and Appetite
In recent decades, the world prevalence of obesity and type 2 diabetes (DMT2) has increased dramatically, resulting in a global epidemic.
- Conditions
- Hyperglycemia, Hyperglycemia, Postprandial, Appetitive Behavior, Hyperinsulinism
- Trial name
- NTRCR-vivo (NCT05528874)
- Testing
- Same intervention for both groups: glycaemic index assessment of 3 biscuits recipes, Crossover: Recipe 4 before recipe 5, Crossover: Recipe 5 before recipe 4
- Where
- Italy
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Hyperglycemia
The Effect of American Ginseng Root and Its Components on Glycemia in Healthy Individuals
To determine the effect of polysaccharides from American ginseng root on postprandial glycemia in healthy individuals.
- Trial name
- NCT00367926
- Testing
- American ginseng root / polysaccharides
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Risk Factor Modification Centre
Diabetes Mellitus
Intraoperative Dexamethasone and Its Effect on Hyperglycemia
To study the effect of intra-operative dexamethasone on the management of post-operative blood sugar in diabetic patients.
- Trial name
- NCT03646916
- Testing
- Dexamethasone, No dexamethasone
- Where
- United States
- Sponsor
- Ascension Health
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