Clinical trials: Embryo
Chromosomal Abnormalities
Preimplantation Genetic Screening in Women of Advanced Maternal Age
An increased incidence of aneuploid pregnancies has been reported in women of advanced maternal age, with higher miscarriage rates.
- Trial name
- NCT00795795
- Testing
- Preimplantation Genetic Screening, IVF without PGS
- Where
- Spain
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Aneuploidy
Aneuploidies and Different Stimulation Protocols
Our working hypothesis is that patients undergoing "in vitro" fertilization (IVF) with higher response to ovarian stimulation protocols recover a higher number of oocytes and, this elevated response could be translated into…
- Trial name
- NCT00802295
- Testing
- Gonadotrophins, Low dosis Gonadotrophin
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
IVF
Immediate Versus Postponed Freeze-all Embryo Transfer in Hyperresponders
This is a multicenter, randomised controlled trial. The investigators plan to randomise 836 participants to the immediate FET or the postponed FET from the day of oocyte retrieval to the last day of that menstrual cycle in a 1:1…
- Trial name
- NCT05483270
- Testing
- the timing of embryo transfer in freeze-all cycles
- Where
- China
- Volunteers
- 845 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Vaginal Flora Imbalance
Vaginal Microbiome and IVF Pregnancy Outcome
The aim of this prospective, observational study is to investigate the prevalence of vaginal dysbiosis among women undergoing IVF procedures in the US.
- Trial name
- NCT05150639
- Testing
- IVF
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Freya Biosciences ApS
Infertility
The Effect of Baseline Bilateral Uterine Artery Doppler Velocimetry on Obstetric Outcomes in HRT-FET Cycles
Researchers aim to determine how baseline (pre-conceptional) uterine perfusion characteristics affect implantation rates and obstetric complications in women who underwent high-quality blastocyst transfer.
- Trial name
- NCT05526014
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Clinical Pregnancy Rate
Does the Volume of the Embryo Culture Medium During Embryo Transfer Affects the IVF Outcomes?
The aim of this study was to evaluate if higher volume (40-45μl VS 20-25 μl) of media used for embryo transfer affects the clinical outcomes in fresh IVF cycles.Patients who fulfilled the inclusion criteria and agreed to…
- Trial name
- NCT03350646
- Testing
- Volume of medium during embryo transfer
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Aretaieion University Hospital
Infertility
Comparison of 5 Day Embryo Transfer With 2-3 Day Transfer in Patients With Previous In Vitro Fertilization Failure
The purpose of this study is to determine whether embryo transfer on day 3 versus day 5 shows a significant difference in implantation, clinical pregnancy, live birth, miscarriage and multiple pregnancy rates among women with at…
- Trial name
- NCT01107002
- Testing
- Day 5 embryo transfer group
- Where
- Iran
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Infertility
Metabolomics Non Selection Study - Vitrolife Media
In this study, study investigators will collect embryo culture media on day 5 of vitro fertilization (IVF) culture, prior to vitrification and embryo transfer for testing via Metabolomic screening.
- Trial name
- NCT04976920
- Testing
- Overture Metabolomics Embryo Selection
- Where
- 2 sites in Argentina, Spain
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Overture Life
Infertility
Comparison of Transfers of Thawed Blastocysts Versus Blastocysts Derived From Thawed Bipronuclear Oocytes
The purpose of this study is to determine if cryopreservation at the blastocyst stage followed by embryo thaw and transfer is as effective as cryopreservation of bipronuclear oocytes followed by post-thaw extended culture (PTEC)…
- Trial name
- NCT01247987
- Testing
- Blastocyst cryopreservation, Bipronuclear oocyte cryopreservation
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Bruce Shapiro M.D.
Low Oxygen Tension
The Effect of Embryo Culture Under Low Oxygen Tension on Pregnancy Rates
This study will determine whether the use of low oxygen tension during "in vitro" embryo culture may increase the pregnancy rates in women undergoing egg donation.
- Trial name
- NCT01532193
- Testing
- Decreased oxygen concentration
- Where
- Spain
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Implantation, Embryo
A Novel Approach to Endometrial Preparation in Recipients of Donor Eggs
This study compares two different methods to prepare the uterine lining of recipients for implantation in cycles using donor eggs. The study method requires less time than the standard method.
- Trial name
- NCT01424618
- Testing
- Leuprolide, Ganirelix
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kelly, Maureen, M.D.
Infertility
Application of Two Different Synthetic Sequential Media for the Human IVF-Embryo Transfer (IVF-ET) Program
Quality-controlled commercial media have been used in many in-vitro fertilization (IVF) laboratories. However, commercial media are costly and difficult to compare directly because their exact compositions are not clearly…
- Trial name
- NCT01356238
- Testing
- MRC media, Sydney IVF media
- Where
- South Korea
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Maria Fertility Hospital
in Vitro Fertilization
Embryo Transfer With Self-spent Culture Medium
Embryo Transfer With Self-spent Culture Medium or new Culture Medium in Vitro Fertilization - Embryo Transfer Process, to analyze which way can improve clinical pregnancy outcomes, is there a significant difference between the…
- Trial name
- NCT03728140
- Testing
- Self-spent Culture Medium
- Where
- China
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- Bin Wu
Clinical Pregnancy After Single Embryo Transfer
Embryo Selection by Time Lapse Monitoring for Single Embryo Transfer ("SET")
A multiple pregnancy is an undesired outcome of assisted reproduction. Current embryo selection technologies are inefficient in identifying the embryo with the highest implantation potential.
- Trial name
- NCT01694641
- Testing
- time-lapse morphokinetic evaluation
- Where
- 2 sites in Hungary
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Dunamenti REK Istenhegyi IVF Center
Infertility, Infertility, Female
The Outcome of Two Protocols Used to Prepare Endometrium for Frozen Embryo Transfer
This is a RCT to test the outcome of two protocols used for preparation of the endometrium for frozen blastocyst embryo transfer
- Conditions
- Infertility, Infertility, Female, Infertility, Male
- Trial name
- NCT04507022
- Testing
- Estradiol Valerate, Progesterone, Aromatase inhibitor
- Where
- Egypt
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Rahem Fertility Center
Fertilization in Vitro, Infertility
The Impact of the Timing of Trigger on IVF Success
The aim of this study is to examine the length of ovarian stimulation with the timing of trigger in an IVF cycle and its potential to impact patient outcomes.
- Conditions
- Fertilization in Vitro, Infertility, Embryonic Development
- Trial name
- NCT02990949
- Testing
- Timing of trigger
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Colorado Center for Reproductive Medicine
Infertility, Aneuploidy
Invasive PGT-A Embryo Selection Versus Non Invasive PGT-A Assisted Embryo Selection
This is a prospective randomised study of the evaluation of the clinical IVF results after invasive PGT-A embryo selection versus Non-invasive PGT-A assisted embryo selection in subfertile women.
- Conditions
- Infertility, Aneuploidy, Chromosome Abnormality
- Trial name
- NCT05547555
- Testing
- embryo selection
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assisting Nature
Infertility
Vaginal Culture Using INVOcell Compared to Traditional IVF Incubation
The purpose of this study is to evaluate intravaginal culture using the medical device INVOcell to generate day 5 blastocysts in comparison to traditional IVF.
- Trial name
- NCT02363426
- Testing
- INVOcell Culture Device, IVF Incubation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Invaron Pharmaceuticals Inc.
Early Pregnancy, Early Pregnancy Loss
EARLY-PREG: A Preconception Cohort Study Based on Counterfactuals to Study Maternal-Embryonic Molecular Interactions
EARLY-PREG is an open-cohort clinical study with a preconception, longitudinal, bidirectional and counterfactual design. The aim of this cohort is to investigate the proteomic signatures of maternal-embryonic communication by…
- Conditions
- Early Pregnancy, Early Pregnancy Loss, Childbirth, Healthy
- Trial name
- EARLY-PREG (NCT07358026)
- Testing
- EMBRYO EXPOSURE
- Where
- Chile
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- MELISA Institute Genomics & Proteomics Research SpA
Infertility, Obesity
Metabolomic Embryo Profiles of Obese in Vitro Fertilization (IVF) Patients and Their Relationship With Polycystic Ovary Syndrome (PCO)
The present study aims to elucidate if there is a metabolomic profile alteration in the embryos of obese women in order to understand if the reduced implantation rate observed in these patients is directly related to this factor.
- Trial name
- NCT01448863
- Testing
- Culture medium metabolomic analysis
- Where
- 2 sites in Spain
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA