Clinical trials: Embryo
Infertility, Endometriosis
Platelet Rich Plasma Uterine Infusion
Platelet Rich Plasma (PRP), a rich source of important growth factors, has been shown to significantly affect the body's ability to heal and regenerate tissues.
- Trial name
- NCT06621342
- Testing
- PRP Experimental
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
HCG Day Follicle Diameter, Reproduction Results
Comparison of Follicle Diameter on hCG Day and Follicle Diameters on OPU (Oocyte Pick up) Day and the Effect of Follicle Diameters on Embryo Development and Pregnancy Outcomes
Evaluation of follicle diameters on human chorionic gonadotrophin(hCG) day and oocyte pick up (OPU) day of follicles developing after gonadotropin treatment, the relationship between follicle diameter and maturation in oocytes…
- Trial name
- NCT04679688
- Testing
- descriptive
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Infertility, Miscarriage, Recurrent
ANXA5 M2 Haplotyping in IVF Patients and Embryos
This study aims to characterize the association between history of pregnancy complications and M2 carrier status in IVF patients and the utility of M2 haplotype preimplantation genetic testing (PGT) in embryos produced by carrier…
- Conditions
- Infertility, Miscarriage, Recurrent, Pregnancy Complications
- Trial name
- NCT04544462
- Testing
- M2 Test
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Genomic Prediction Inc.
Embryo Implantation, Infertility
Clinical Trial of Novel Implantation Promoting Medium (EmbryoGlue) to Improve IVF Success Rates
Hypothesis: a special solution for improving human embryo implantation, when added to the solution during embryo transfer, will improve implantation rates in embryo transfers using previously frozen embryos.
- Trial name
- NCT00588250
- Testing
- EmbryoGlue
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Infertility, Female, Frozen Embryo Transfer
Luteal Phase Support During Frozen Embryo Transfer Cycle
We aimed to decrease quantity of exogenous estrogen and evaluated the success rate of ongoing pregnancy in women undergone artificial FET who have a surplus embryos at previous fertility treatment cycles.
- Trial name
- NCT04013438
- Testing
- Strogen
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Embryonic Development, Retinal Anomalies
Mapping of the Developmental Atlas of the Visual System and Research on Embryonic Neurogenesis Phenomena
This research studies how nerve cells in the human embryonic retina, visual brain regions, and brain areas responsible for higher cognitive functions grow, develop, and form interconnected functional networks.
- Conditions
- Embryonic Development, Retinal Anomalies, Neural Development
- Trial name
- NCT07688538
- Testing
- Tissue collection and multi-omics sequencing analysis
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sheng Liu
Genetic Disorder, Fertility Disorders
Retrospective Study on Clinical Results of Preimplantation Genetic Screening at Different Embryo Stage
Preimplantational genetic screen (PGS) is tool for diagnosis of embryo chromosome abnormality before transfer. Under this tool, patients with a family history of genetic disease or special genetic disease could avoid to produce…
- Conditions
- Genetic Disorder, Fertility Disorders, Reproductive Disorder
- Trial name
- NCT03065114
- Testing
- PGS
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Yeh
Infertility, IVF
Quality of Human Embryos in IVF, Culturing in Differentiated Oxygen
The goal of this clinical trial is to evaluate the importance of differential O2 tension to the developing embryos. As a secondary aim, we investigate the levels of reactive oxygen species (ROS) in spent media from the developing…
- Conditions
- Infertility, IVF, Embryo
- Trial name
- NCT05737381
- Testing
- Differential oxygen tension
- Where
- Denmark
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Anxiety, Depression
Coping Intervention After Embryo Transfer
Background of the study: Undergoing an IVF or ICSI treatment is an emotional and physical burden for both the woman and her partner.
- Trial name
- NCT01701011
- Testing
- Coping intervention
- Where
- Netherlands
- Volunteers
- 377 people, healthy volunteers welcome
- Sponsor
- Bart CJM Fauser
Infertility
Natural Cycle/Progesterone Fortified Protocol for Endometrial Preparation for Frozen/Thawed Embryo Transfer
This is a pilot study of a novel protocol for preparation of the endometrium for frozen/thawed embryo transfer whereby estrogen is not administered during the proliferative phase and progesterone is administered through vaginal…
- Trial name
- NCT02749344
- Testing
- FET after endometrial preparation
- Where
- Israel
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Infertility
Assesment of Embryo Viability and Re-expansion After Thawing in Blastocyst Stage Embryos
In this prospective study, the possible effects of embryo viability and degree of blastocele re-expansion on pregnancy outcomes before vitrified/thawed blastocyst transfer will be evaluated.
- Trial name
- NCT05474833
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Infertility
Morphometrics and Morphokinetics of Thawed Oocytes and Embryos
The aim of this observational study is to describe for the first time a complete set of morphometric and morphokinetic parameters of frozen-thawed human embryos in order to select the embryo with the highest implantation…
- Trial name
- NCT02639715
- Volunteers
- 1,272 people, healthy volunteers welcome
- Sponsor
- Sophie Debrock
Pregnancy
The Effect of Acupuncture on Pregnancy Rates in Women Undergoing Embryo Transfer
The present study is designed to test the hypothesis that acupuncture, before and after embryo transfer, significantly improves pregnancy rates, compared to embryo transfer with sham acupuncture and no acupuncture at all.
- Trial name
- AcuIVF (NCT00722462)
- Testing
- Active acupuncture
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ottawa Fertility Centre
Embryo Transfer, Intrauterine Insemination (IUI)
Semi-quantitative Pregnancy Test to Monitor hCG Levels After Assisted Fertility Treatment
Given the potential of semi-quantitative pregnancy tests as part of assisted fertility care, the investigators would like to document the feasibility and acceptability of a semi-quantitative pregnancy test as an adjunct to or…
- Trial name
- NCT01919502
- Testing
- Semi-quantitative urine pregnancy test
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Colorectal Cancer
Efficacy of Single Incision (Embryonic NOTES) Laparoscopic Colorectal Surgery
Laparoscopic colon surgery has been performed widely. As a minimal invasive approach, single incision (Embryonic NOTES) colon surgery has been attempted.
- Trial name
- NCT01269060
- Testing
- Single Incision Laparoscopic Surgery
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
In Vitro Fertilization, Assisted Reproductive Techniques
Optimizing IVF Treatment - the Impact of Time-lapse Culture and Preimplantation Factor (PIF) on Embryo Development.
The aims of this study are to evaluate: 1. the possible effect of time-lapse culture from day zero (day of oocyte retrieval) on fertilisation rates and embryo quality in standard IVF. 2.
- Trial name
- NCT02222831
- Testing
- Day 0 denudation and time lapse culture on IVF-oocytes.
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Regionshospitalet Viborg, Skive
Recurrent Implantation Failure in Setting of Artifically Prepared Endometrium
Trial of Endometrial Scratch Prior to Frozen Embryo Transfer in Patients With Recurrent Implantation Failure
Patients with a history of recurrent implantation failure who are planning a frozen embryo transfer (FET) are enrolled into the program.
- Trial name
- NCT03157765
- Testing
- endometrial biopsy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brown Fertility
Infertility
Screening of Low Responders for Aneuploidy to Improve Reproductive Efficiency
The purpose of this study is to assess the impact of Comprehensive Chromosome Screening(CCS) on patients with low ovarian reserve in an effort to improve success during in vitro fertilization and decrease the time to successful…
- Trial name
- Solaire (NCT01977144)
- Testing
- Comprehensive Chromosomal Screening
- Where
- United States
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Poor Ovarian Response
SIRT3 Expression in Granulosa Cells and the Levels of Follicular Fluid Metabolites Among POR Subgroups
The goal of this prospective, observational study is to learn about the pathogenesis and biological target of the subtypes of poor ovarian response (POR) during In vitro fertilization and embryo transfer (IVF-ET).
- Trial name
- POR SIRT3 (NCT06617988)
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shandong University of Traditional Chinese Medicine
Infertility
Embryo Development Using Two Commercial Single-step Media
This prospective study with sibling oocytes will evaluate the efficiency of two commercial single-step media, namely Sage 1-step and Continuous Single Culture Medium (CSCM), in terms of embryo utilization rates, blastocyst…
- Trial name
- NCT02302638
- Testing
- embryo culture in different single-step media
- Where
- Greece
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Eugonia