Clinical trials: Emergencies
Pregnancy Prevention
Oral Levonorgestrel Plus Meloxicam, IG-002 Delays Ovulation in Normal Menstruating Women by Seven Days
This clinical trial determines if an oral medication taken within 2 days of anticipated ovulation will delay ovulation by 7 days.
- Trial name
- OVULATION (NCT05695352)
- Testing
- Levonorgestrel 1.5mg, Meloxicam 15 mg
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- InnovaGyn, Inc.
Advance Care Planning
Evaluating the Integration of the Recommended Summary Plan for Emergency Care Treatment (ReSPECT) Into Primary Care
When a person becomes seriously ill health professionals treating them need to make decisions quickly. They may have limited information about the person's medical history or about their wishes about treatment.
- Trial name
- NCT05046197
- Where
- United Kingdom
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- University of Warwick
Colorectal Cancer
Text-based Colorectal Cancer Prevention Pilot
In this project, we intend to conduct a randomized pilot trial of a structured behavioral intervention, grounded in the Theory of Planned Behavior and Self-Determination Theory, to promote adherence of patients aged 45 - 75 to…
- Trial name
- NCT05004376
- Testing
- Text Messaging
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Chest Infection, Pulmonary Edema - Acute
Grasshopper: a Novel Clinical Dashboard for Radiologists
Does a radiology clinical dashboard increase radiologist use of specific reporting language for chest X-rays (CXRs) and thereby decrease rates of unnecessary Emergency Department (ED) prescriptions and follow-up imaging?
- Trial name
- Grasshopper (NCT06785246)
- Testing
- Grasshopper dashboard
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
High Intensity Users, Frequent Attenders
Exploring the Needs of HIU Patients Within the Emergency Department
The aim of this qualitative interview study is to explore the unmet needs of patients who frequently attend the emergency department and the challenges of the staff who support them.
- Trial name
- HIU ED (NCT06985979)
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- East Lancashire Hospitals NHS Trust
Emergency Contraception
Clinical Follow-up and Outcomes of Pregnancies Exposed to Ella
The study is aimed at assessing the clinical follow-up and the outcomes of pregnancies exposed to ella, whether due to failure of the emergency contraception or inadvertent exposure during pregnancy.
- Trial name
- ellipseII (NCT01569737)
- Testing
- ella
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- HRA Pharma
Postoperative Pain, Laparotomy
Transversus Abdominis Plane Block Versus Erector Spinae Plane Block
The TAP block, first described by Rafi in 2001, is comprised of deposition of a local anesthetic into the anatomical plane between the internal oblique and transverses abdominis muscles, where thess thoracoabdominal nerves…
- Trial name
- NCT03989570
- Testing
- transversus abdominis plane block, erector spinae plane block, control group
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hassan Mokhtar Elshorbagy Hetta
Rapid Sequence Intubation
Pre-oxygenation With Real Time End-tidal Oxygen Measurements Versus Single Breath Measurements
This study examines the performance of a nasal cannula end-tidal oxygen (EtO2) measurement as compared to the gold standard of single breath end-tidal oxygen measurements in healthy volunteers.
- Trial name
- NCT03840486
- Testing
- Non-rebreather mask (NRBM), Non-invasive ventilator mask (NIV), Nasal cannula EtO2 sensor
- Where
- 2 sites in United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Emory University
Brain Injuries, Pulmonary Embolism
Improving the Stewardship of Diagnostic Imaging Resources in Alberta Emergency Departments
Utilization of diagnostic imaging in the Emergency Department has increased dramatically over the past two decades, driven by an increased availability of advanced imaging, legal pressures to exclude serious diagnoses in low-risk…
- Trial name
- NCT02410941
- Testing
- Clinical decision support
- Where
- 16 sites in Canada
- Volunteers
- 52,058 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Reproductive Behavior, Sexual Behavior
Reducing Teen Pregnancy in the Emergency Department
This study will determine the feasibility, acceptability, and potential efficacy of an emergency department-based pregnancy prevention intervention targeting sexually active adolescent female emergency department patients.
- Conditions
- Reproductive Behavior, Sexual Behavior, Adolescent Behavior, Contraception
- Trial name
- ERICA (NCT03866811)
- Testing
- Dr. Erica
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Columbia University
Psychiatric Emergency, Aggression
TREC-Lebanon: A Trial for Rapid Tranquilisation for Agitated Patients in the Emergency Setting
This is a randomised controlled trial comparing haloperidol + promethazine versus haloperidol + promethazine + chlorpromazine for agitated patients in the emergency department.
- Conditions
- Psychiatric Emergency, Aggression, Agitation
- Trial name
- TREC (NCT03639558)
- Testing
- Haloperidol + Promethazine + Chlorpromazine, Haloperidol + Promethazine
- Where
- 2 sites in Lebanon
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Joseph Dib
LRTI, Sepsis
Prospective Study to Characterize Host-pathogen Related Factors in Hospitalized and ED Patients With LRTI and/or Sepsis
The TAILORED-Treatment consortium was established to develop new tools aimed to increase the effectiveness of antibiotic and antifungal therapy, reduce adverse events, and help limit the emergence of antimicrobial resistance in…
- Conditions
- LRTI, Sepsis, Fungal Infections, Bacteremia
- Trial name
- TailoredT (NCT02025699)
- Where
- Israel
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- MeMed Diagnostics Ltd.
Stress, Burnout
Music Therapy and Humanization in ED Healthcare Professionals
Background: Healthcare professionals in emergency departments frequently experience stressful situations that could jeopardize their mental health, sense of purpose, and ability to empathize with patients, families, and…
- Conditions
- Stress, Burnout, Quality of Life (QOL), Music Therapy
- Trial name
- NCT06939426
- Testing
- Music therapy intervention
- Where
- Colombia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Fundación Santa Fe de Bogota
Anxiety, Covid-19 Fear
Emotional Freedom Technique (EFT) Effect on Nurses
It has been planned to determine the effect of EFT, which effectiveness has been determined by the studies, on the covid-19 fear and anxiety experienced by the nurses working in the emergency department.
- Trial name
- EFT (NCT04910516)
- Testing
- Emotional Freedom Techniques (EFT)
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Marmara University
Pediatric Readiness
Pediatric Readiness Intervention in Manitoba
The goal of this clinical trial is to improve emergency care of children in Manitoba by increasing the weighted pediatric readiness scores (WPRS) of the general EDs through the implementation of provincially derived…
- Trial name
- NCT06257524
- Testing
- Education and training
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Cardiopulmonary Arrest, Resuscitation
Reducing Prehospital Medication Errors & Time to Drug Delivery by EMS During Simulated Pediatric CPR
The study investigators will recruit paramedics in many Emergency Medical Services (EMS) in Switzerland to prepare direct intravenous (IV) emergency drugs during a standardized simulation-based pediatric out-of-hospital cardiac…
- Conditions
- Cardiopulmonary Arrest, Resuscitation, Pediatrics, Medication Errors
- Trial name
- NCT03921346
- Testing
- Mobile device app (PedAMINES™) 1st drug, Mobile device app (PedAMINES™) 2nd drug, Mobile device app (PedAMINES™) 3rd drug
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Pediatric Clinical Research Platform
Performance
Physicians Performance After Night Shifts
Emergency medicine is one of the professional activities integrating a night activity into working time. Concerns about the sleep deprivation that this activity generates have been growing for the past thirty years.
- Trial name
- URGENCE24 (NCT05250089)
- Testing
- Simulation
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Hypobaric Hypoxia, Hypobaric Normoxia
Cognition at Altitude in HEMS - Part II
The aim of the current study is to evaluate under blinded conditions, both in a simulated environment and during helicopter flight, the effect of a rapid (within 20 minutes) exposure to altitude (4000 m asl) on physiological…
- Conditions
- Hypobaric Hypoxia, Hypobaric Normoxia, Cognitive Performance, Emergency Medicine
- Trial name
- HEMS II (NCT05073406)
- Testing
- Altitude exposure in hypobaric normoxic condition, Altitude exposure in hypobaric hypoxic condition
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Institute of Mountain Emergency Medicine
Abdominal Pain, Flank Pain
Real Time Remote Tele-Mentored Ultrasonography in the ED
The goal of this pilot study is to evaluate the use of real time remote tele-mentored ultrasound in the emergency department at hospitals with physician shortage designation.
- Trial name
- ED RTMUS (NCT05635214)
- Testing
- real time remote tele mentored ultrasound exam
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Headache, Intranasal Ketamine
"THINK Trial: Treatment of Headache With IntraNasal Ketamine: A Randomized Controlled Trial Evaluating the Efficacy of Intranasal Ketamine Versus Standard Therapy in the Management of Primary Headache Syndromes in the Emergency Department"
This is a randomized, single-blind, placebo controlled trial to evaluate the efficacy of sub-dissociative dose ketamine versus standard care therapy for acute headache management of in patients presenting to the emergency…
- Trial name
- THINK (NCT03081416)
- Testing
- Ketamine, Normal saline, Metoclopramide
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center