Clinical trials: Emergency Contraception
Contraceptive Usage
Disparities in Emergency Contraceptive Metabolism Dictate Efficacy
The purpose of this study is to learn more about why some people are at greater risk for oral emergency contraceptive failure while others are not.
- Trial name
- NCT05674513
- Testing
- Ulipristal acetate
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Pregnancy in Adolescence, Counseling
Reducing Adolescent Pregnancy
This multi-site study is employing a brief contraception counseling intervention in the Emergency Department (ED) to shed light on factors that affect decision making as well as barriers and facilitators to conception initiation…
- Conditions
- Pregnancy in Adolescence, Counseling, Contraception Behavior
- Trial name
- NCT04120376
- Testing
- Contraception Counseling
- Where
- 2 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Pregnancy Prevention
Oral Levonorgestrel Plus Meloxicam, IG-002 Delays Ovulation in Normal Menstruating Women by Seven Days
This clinical trial determines if an oral medication taken within 2 days of anticipated ovulation will delay ovulation by 7 days.
- Trial name
- OVULATION (NCT05695352)
- Testing
- Levonorgestrel 1.5mg, Meloxicam 15 mg
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- InnovaGyn, Inc.
Contraception, Body Weight
Emergency Contraception and Body Weight: Pilot Study
The purpose of this research study is to determine how body weight changes the drug level of an emergency contraceptive pill containing a hormone called levonorgestrel (LNG).
- Trial name
- NCT02408692
- Testing
- ECx1, ECx2
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Contraception
Study Comparing Emergency Contraception Effectiveness in Women Who Weight ≥ 80 kg
The proposed research study is a Phase IIb, multi-center, single-blind, randomized study of UPA 30 mg, LNG 1.5 mg and LNG 3.0 mg to evaluate EC effectiveness in women with weight ≥ 80 kg who present within 72 hours of unprotected…
- Trial name
- NCT03537768
- Testing
- Ulipristal Acetate, Levonorgestrel
- Where
- 18 sites in United States
- Volunteers
- 532 people, healthy volunteers welcome
- Sponsor
- Kimberly Myer
Contraception Behavior
Hormonal Contraceptive Health Education for Adolescent Males
Prospective randomized control trial of an educational electronic application on female hormonal contraception for adolescent males in the pediatric emergency department.
- Trial name
- NCT03400410
- Testing
- Education Arm
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Contraception
Administration of Oral Contraceptives at Different Times of the Follicular Phase of the Menstrual Cycle
We hypothesize that administration of OCs at varying follicular diameters will provide an appropriate model for the study of follicular atresia in women.
- Trial name
- NCT00204438
- Testing
- 0.15mg desogestrel /0.03mg ethinyl estradiol
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Obesity
Effects of Obesity on Pharmacokinetics of the Levonorgestrel Emergency Contraceptive Pill
The purpose of this study is to determine the effects of obesity on the pharmacokinetics of the levonorgestrel (LNG) only emergency contraceptive (EC) regimen and on markers of ovulation Primary hypothesis: 1) Obese users of…
- Trial name
- NCT02104609
- Testing
- Levonorgestrel 1.5mg by mouth once
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Contraception
Impact of Combined Hormonal Contraceptives on UPA
The purpose of this research study is to determine if taking a birth control pill effects how well an emergency contraceptive pill called Ulipristal acetate (UPA) works.
- Trial name
- NCT02577601
- Testing
- Ulipristal Acetate, Levonorgestrel (LNG)/Ethinyl estradiol birth control pill
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Pregnancy, Sexually Transmitted Diseases
Increased Access to Emergency Contraceptive Pills
This study will evaluate the effect of easy access to emergency contraceptive pills (ECPs) on the rates of pregnancy and sexually transmitted infections (STIs).
- Trial name
- NCT00060463
- Testing
- Increased access to emergency contraceptive pills
- Where
- 2 sites in United States
- Volunteers
- 1,490 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Ovulation, Luteal Development
The Effect of a Non-hormonal Cox-2 Inhibitor (Celebrex) on Ovulation
The purpose of this study is to assess the effect that Celebrex (a COX-2 inhibitor and non-steroidal anti-inflammatory drug) has on ovulation.
- Trial name
- NCT01129245
- Testing
- Celebrex
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Obesity
Effectiveness of Orally Dosed Emergency Contraception in Obese Women - LNG
Obese women are significantly more likely than their normal BMI counterparts to experience failure of orally-dosed emergency contraceptives.
- Trial name
- EC-Obesity (NCT02863445)
- Testing
- Levonorgestrel-based emergency contraception 1.5 mg, Levonorgestrel-based emergency contraception 3.0mg
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Unmet Need for Contraception, Uptake of HIV Prevention
Mobile Health Supported Self-care Among Tertiary Education Students in Zimbabwe
Young people of ages 15-24 years, particularly those in Sub-Saharan Africa, do not optimally take up HIV services (HIV testing, HIV prevention and HIV treatment) and contraception.
- Conditions
- Unmet Need for Contraception, Uptake of HIV Prevention, Healthy Participants
- Trial name
- MASCOT (NCT07403318)
- Testing
- MASCOT
- Where
- Zimbabwe
- Volunteers
- 16,000 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Pregnancy, Unplanned, Pregnancy; Accident
Levonorgestrel Intrauterine System For Emergency Contraception
The purpose of this research study is to test the levonorgestrel intrauterine system as a method for emergency contraception. Emergency contraception refers to pregnancy prevention after an act of intercourse.
- Trial name
- LIFE (NCT01539720)
- Testing
- Ulipristal acetate, levonorgestrel IUS
- Where
- 3 sites in United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood of the St. Louis Region and Southwest Missouri
Obesity, Contraception
Effectiveness of Orally Dosed Emergency Contraception in Obese Women - UPA
Obese women are significantly more likely than their normal BMI counterparts to experience failure of orally-dosed emergency contraceptives.
- Trial name
- UPA-Obesity (NCT02859337)
- Testing
- UPA-ECx1, UPA-ECx2
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Emergency Contraception, Healthy, Reproductive Age Women
Application for the Etonogestrel/Ethinyl Estradiol Ring
This study is enrolling healthy women ages 18-39yo who are not pregnant or breastfeeding, and are not using hormonal birth control.
- Trial name
- AFTER (NCT03120728)
- Testing
- Etonogestrel/ethinyl estradiol contraceptive vaginal ring
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Postcoital Contraception
Emergency Contraception - User's Profile
Retrospective analysis of requests of emergency hormonal contraception using pharmacy protocols registered in 2003 and 2006.
- Trial name
- NCT01771016
- Volunteers
- 729 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Post Partum
Advance Supply of Emergency Contraception Compared to Routine Postpartum Care in Teens
This is a pilot randomized controlled trial to assess the effects of advanced supply of emergency contraception versus routine care in a teen postpartum population.
- Trial name
- NCT00433004
- Testing
- Plan B (Levonorgestrel)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Contraception
Drospirenone-only Pill as Emergency Contraception
Emergency contraception (EC) provides an additional measure to help prevent pregnancy after unprotected intercourse or contraceptive failure.
- Trial name
- NCT05675644
- Testing
- Drospirenone-only pill
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Contraception
Human Ovarian Follicular Dynamics and Emergency Contraception
The researchers hypothesize that emergency contraception (EC) will initiate the changes associated with atresia or ovulatory failure at all stages of follicular development and that the image attributes associated with atresia…
- Trial name
- NCT00204451
- Testing
- 0.75 levonorgestrel, 50 mg ethinyl estradiol/0.5 mg levonorgestrel
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan